Day: October 13, 2021

An article Effects of anise, clove and thyme essential oils supplementation on rumen fermentation, blood metabolites, milk yield and milk composition in lactating goats WOS:000612162700024 published article about VITRO GAS-PRODUCTION; BERRY ESSENTIAL OILS; RUMINAL FERMENTATION; NUTRIENT DIGESTIBILITY; MICROBIAL FERMENTATION; GROWTH-PERFORMANCE; CONTINUOUS-CULTURE; DAIRY-COWS; METHANE EMISSION; LIPID-SYNTHESIS in [El-Essawy, Abeer M.; Abdel-Wahed, A. M.; Abdou, Ahlam R.] Desert Res Ctr, Anim & Poultry Nutr Dept, Cairo 11753, Egypt; [Anele, U. Y.] North Carolina Agr & Tech State Univ, Greensboro, NC 27411 USA; [Khattab, I. M.] Matrouh Univ, Fac Desert & Environm Agr, Dept Anim & Fish Prod, Matrouh 51744, Egypt in 2021.0, Cited 76.0. Category: indole-building-block. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

The present study evaluated the effects of essential oil (EO) from anise (AO), clove (CO) and thyme (TO) on the performance of lactating Shame goats. Eight lactating Shame goats with average body weight 34.90 +/- 0.9 kg and 3 years old were randomly assigned to four treatments in a duplicated 4 x 4 Latin square design, with four periods of 22 days. In each period, the goats were adapted to the treatments for 15 days and the remaining 7 days was used for sample collection. Goats were fed a basal diet without supplementation (control) or supplemented with anise (AO), thyme (TO) or clove (CO) at a daily dose of 2 mL/head/d. Feed intake was not affected by EO supplementations. Digestibility of organic matter, ether extract and acid detergent fibre was higher (P < 0.05) with EO supplementations when compared with the control. Supplementations of EO had no effect on milk (g/d) yield, protein and lactose, as well as the composition (g/kg) of protein and lactose. Fat yield (g/d) and fat content (g/kg) were greater (P < 0.05) in EO supplemented goats versus those on the control diet. Compared with control, ruminal ammonia-N was not affected whereas, ruminal pH was increased (P = 0.02) with EO supplementations. Rumen total volatile fatty acid concentration and molar proportion of acetate (C2) were higher (P < 0.05) in goats fed CO and TO compared to control, whereas propionate (C3) and butyrate (C4) and C2:C3 proportions were unchanged with EO inclusion. With the exception of a decrease (P = 0.05) in blood urea nitrogen (BUN) with EO supplementations, other blood parameters were not affected. Milk C8 and C12 fatty acids (FA) were lower (P < 0.05) with EO supplementations compared with control. Composition of unsaturated and monounsaturated FA was higher (P < 0.05) and polyunsaturated FA was decreased (P < 0.05) with EO supplementations compared with control. Proportions of C18:1 n-9 C18:3 n-3 and n-3 FA were increased (P < 0.05) and proportions of C18:3 n-6 C20:4 n-6 and n-6 FA were decreased (P < 0.05) in goats fed EO compared to the control group. Overall, all three EOs tested in this study had beneficial effects on digestion, rumen fermentation parameters and milk composition including milk FA profile. Supplementation of CO and TO tended to increase PUFA concentration in the milk which supports their recommendation in the diet of lactating ruminants. Category: indole-building-block. About 4-Methoxybenzaldehyde, If you have any questions, you can contact El-Essawy, AM; Anele, UY; Abdel-Wahed, AM; Abdou, AR; Khattab, IM or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Name: Benzyl Alcohol. Recently I am researching about BIOLOGICAL EVALUATION; INHIBITORS; NUCLEOTIDE; ISOFLAVONES; ANALOGS; T-705, Saw an article supported by the National Science Foundation for Young Scientists of China [21502209]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2016T90395]. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Guo, S; Xu, MS; Guo, Q; Zhu, FQ; Jiang, XR; Xie, YC; Shen, JS. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol

To explore the application potential of dual prodrug strategies in the development of anti-HCV agents, a variety of sofosbuvir derivatives with modifications at the C4 or N3 position of the uracil moiety were designed and synthesized. Some compounds exhibited potent anti-HCV activities, such as 4e and 8a-8c with similar EC50 values (0.20-0.22 mu M) comparative to that of sofosbuvir (EC50= 0.18 mu M) in a genotype 1b based replicon Huh7 cell line. Moreover, 8b displayed a good human plasma stability profile, and was easily metabolized in human liver microsomes expectantly. On the other hand, aiming to discover novel anti-HCV nucleosides, pyrazin-2(1H)-one nucleosides and their phosphoramidate prodrugs were investigated. Several active compounds were discovered, such as 25e (EC50= 7.3 mu M) and S-29b (EC50= 19.5 mu M). This kind of nucleosides were interesting and would open a new avenue for the development of antiviral agents.

Name: Benzyl Alcohol. About Benzyl Alcohol, If you have any questions, you can contact Guo, S; Xu, MS; Guo, Q; Zhu, FQ; Jiang, XR; Xie, YC; Shen, JS or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about NONFERROUS METALS; CARBON-STEEL; M HCL; ADSORPTION; BEHAVIOR; COMPOUND; DFT, Saw an article supported by the AICTE, New Delhi; TEQIP-II of VSSUT, Burla, India. Published in ELSEVIER in AMSTERDAM ,Authors: Upadhyay, A; Purohit, AK; Mahakur, G; Dash, S; Kar, PK. The CAS is 123-11-5. Through research, I have a further understanding and discovery of 4-Methoxybenzaldehyde. Formula: C8H8O2

Corrosion inhibition of mild steel (MS) by a series of 4-aminoantipyrine-based Schiff base has been studied in 1 N HCl aqueous medium adopting electrochemical method at different concentration (10(-2)-10(-5) M) and temperature (303-333 K). All of the inhibitors were found to be dominated by cathodic/anodic in nature (mixed type). Electrochemical impedence and polarization studies were in agreement with each other. The surface morphology (smoothness and roughness) was characterized by SEM, which indicates the formation of protective layer on the MS surface. The substituents on the Schiff bases influence their corrosion inhibition properties. Schiff bases having -OCH3, -OH and -NMe2 substituents exhibit more inhibition tendency as compared to other substituents. The role of cross conjugation in electron donating as well as accepting properties by heteroatom (N, O) and pi-electrons in corrosion inhibition was clearly observed from DFT calculations. Monolayer formation on the MS surface has been confirmed from the Langmuir isotherm fitting. Thermodynamic modeling has been done to understand the nature of adsorption. The values of Delta G (>-30 kJ/mol/K) indicate the existence of both physical and chemical interactions between the Schiff base molecules and metal surface. (C) 2021 Elsevier B.V. All rights reserved.

Formula: C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Upadhyay, A; Purohit, AK; Mahakur, G; Dash, S; Kar, PK or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Exploring the potential of wine industry by-products as source of additives to improve the quality of aquafeed WOS:000527371500101 published article about VITIS-VINIFERA L.; VOLATILE COMPOUNDS; ACID-COMPOSITION; GRAPE; EXTRACT; POMACE; WASTE; FOOD in [Camara, Jose S.; Silva, Catarina; Perestrelo, Rosa] Univ Madeira, CQM, Campus Penteada, P-9020105 Funchal, Portugal; [Camara, Jose S.] Univ Madeira, Fac Ciencias Exatas & Engn, Dept Quim, Campus Univ Penteada, P-9020105 Funchal, Portugal; [Lourenco, Silvia] Inst Politecn Leiria, MARE Marine & Environm Sci Ctr, Av Porto de Pesca, P-2520641 Peniche, Portugal; [Lourenco, Silvia; Andrade, Carlos] Univ Porto, Ctr Interdisciplinar Invest Marinha & Ambiental, CIIMAR CIMAR, Av Gen Norton de Matos S-N, P-4450208 Matosinhos, Portugal; [Lopes, Andre; Andrade, Carlos] OOM, Edificio Madeira Tecnopolo,Piso0, P-9020105 Funchal, Portugal; [Lopes, Andre] Univ Algarve, CCMAR Ctr Ciencias Mar, Campus Gamhelas, P-8005139 Faro, Portugal in 2020.0, Cited 41.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6. Formula: C7H8O

The recent growing concern driven by consumer interest in the safety and quality of seafood, has boosted the search for healthy and functional aquafeeds. The current study represents the first approach to assess the potential of volatile composition of the wine industry by products (e.g., grape pomace, grape stems, lees), as additives for improving the quality of fish feeds in terms of organoleptic characteristics (e.g., aroma and flavor) and health benefits. Headspace solid-phase microextraction followed by gas chromatography-mass spectrometry (HS-SPME/GC-MS) was used to establish the volatile profile of wine industry by-products. A total of 153 volatile organic compounds (VOCs), which belong to different chemical families, comprising 36 esters, 31 carbonyl compound, 20 alcohols, 18 terpenoids, 17 acids, 11 furanic compounds, four volatile phenols, two lactones, and 14 miscellaneous, were identified. Esters and terpenoids showed a positive contribution to the aquafeeds aroma with fruity, sweet, green, fresh, and berry notes, whereas some acids (e.g., hexanoic acid) and terpenoids (e.g., limonene) could be used as antimicrobial, antioxidant and antiproliferative agents. Our findings confirmed the potential of wine industry by-products as a rich source of essential compounds to enhance the quality of aquafeeds towards the valorization of winery waste based on the concept of circular economy. Further investigation on the extraction, isolation and purification of VOCs from a natural bio-source will guarantee the safety of the aquafeed and compliance with the requirements of the animal feed industry.

Formula: C7H8O. About Benzyl Alcohol, If you have any questions, you can contact Camara, JS; Lourenco, S; Silva, C; Lopes, A; Andrade, C; Perestrelo, R or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Zhang, ZW; Rakesh, KP; Liu, J; Qin, HL; Tang, HL in ROYAL SOC CHEMISTRY published article about FDA-APPROVED DRUGS; CATALYZED FLUOROSULFONYLVINYLATION; HYDROLYSIS; SUFEX in [Qin, Hua-Li; Tang, Haolin] Wuhan Univ Technol, Sch Chem Chem Engn & Life Sci, Wuhan 430070, Peoples R China; Wuhan Univ Technol, State Key Lab Adv Technol Mat Synth & Proc, Wuhan 430070, Peoples R China in 2021.0, Cited 40.0. Formula: C7H8O2. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5

Both cis and trans relative configurations of functionalized cyano cyclopropane bearing sulfonyl fluoride moiety were accessed by Corey-Chaykovsky cyclopropanation reactions. This protocol used mild conditions, and obtained good yields with excellent functional group compatibility. Further application of this class of compounds in SuFEx reactions and cyano reductions were also successfully achieved in good yields.

Formula: C7H8O2. About Mequinol, If you have any questions, you can contact Zhang, ZW; Rakesh, KP; Liu, J; Qin, HL; Tang, HL or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Category: indole-building-block. In 2021 ORG BIOMOL CHEM published article about ASSISTED ONE-POT; MULTICOMPONENT SYNTHESIS; ULTRASOUND; WATER; NANOPARTICLES; DERIVATIVES; SCAFFOLDS; CHEMISTRY; PYRAZOLE; DESIGN in [Nazeri, Mohammad Taghi; Shaabani, Ahmad; Notash, Behrouz] Shahid Beheshti Univ, Fac Chem, GC, POB 19396-4716, Tehran, Iran; [Shaabani, Ahmad] RUDN Univ, Peoples Friendship Univ Russia, 6 Miklukho Maklaya St, Moscow 117198, Russia in 2021, Cited 74. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

Small-ring heterocycles comprising pyrrole and pyrazole are well known for their rich biological properties. In this article, an efficient green sonochemical approach was designed for the synthesis of novel, fully substituted pyrroles connected to pyrazole scaffolds via a one-pot, four-component isocyanide-based sequential reaction. This reaction was carried out using various 5-amino-pyrazoles, aldehydes, dialkyl acetylenedicarboxylates and isocyanides for the synthesis of fully functionalized pyrroles with high chemoselectivity in the presence of a catalytic amount of PTSA center dot H2O, in good to excellent yields under ultrasound irradiation. This waste-free (-H2O) reaction exhibited a high atom economy and step economy via creating four new bonds, including two C-N and two C-C bonds, and the formation of two five-member heterocycles which are connected in a single operation. The mechanism of this four-component domino process involved sequential imination-dipolar cyclization-[1,5]-H shift reactions. The synthesized compounds possess interesting fluorescence features, and the bioactive scaffolds might attract great interest in the fields of clinical diagnostics and biomedical research in the future.

Category: indole-building-block. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Nazeri, MT; Shaabani, A; Notash, B or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

I found the field of Chemistry very interesting. Saw the article Rapid and green synthesis of 4H-benzo[b]pyrans using triethanolamine as an efficient homogeneous catalyst under ambient conditions published in 2020.0. Product Details of 100-83-4, Reprint Addresses Moradi, L (corresponding author), Univ Kashan, Dept Organ Chem, Fac Chem, POB 8731753153, Kashan, Iran.. The CAS is 100-83-4. Through research, I have a further understanding and discovery of 3-Hydroxybenzaldehyde

4H-benzo[b]pyrans were obtained rapidly in high yields using triethanolamine as an efficient, eco-friendly and low-cost basic catalyst. One-pot three-component condensation reaction of a series of aldehydes, malononitrile and 1,3-diketones was performed at room temperature. All the products were obtained in high-to-excellent yields and characterized in detail. Green, rapid and mild process, very short reaction times (1-12 min) and simple workup are some of the advantages of this method.

Product Details of 100-83-4. About 3-Hydroxybenzaldehyde, If you have any questions, you can contact Rahnamafa, R; Moradi, L; Khoobi, M or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Rao, RN; Chanda, K in ROYAL SOC CHEMISTRY published article about in [Rao, Ramdas Nishanth; Chanda, Kaushik] Vellore Inst Technol, Sch Adv Sci, Dept Chem, Vellore 632014, Tamil Nadu, India in 2021, Cited 30. Computed Properties of C8H8O2. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

An expeditious microwave assisted one-pot sequential route to synthesize pyrido fused imidazo[4,5-c]quinolines via the Pictet-Spengler cyclization strategy has been developed. In this study, substituted 2-amino pyridines are condensed with 2-bromo-2 ‘-nitroacetophenone to generate imidazo[1,2-a]pyridines with nitro group functionality at C-2 position. Reduction of nitro group to its amine congener in green media followed by the Pictet-Spengler cyclization strategy with substituted aldehydes led to the formation of new C-C and C-N bonds in a one-pot sequential manner. The cyclization proceeds through the CO(carbonyl)-C(H) cleavage of the aldehyde group via oxidative cross-coupling, transamination, cyclization and aromatization steps. Low cost reagents and a green solvent were used to facilitate the architecturally beautiful pyrido fused imidazo[4,5-c]quinoline scaffolds in high yields. The key features of this synthetic protocol are the use of microwave-assisted mild reaction conditions, one-pot sequential pathway, broad substrate scope and green media, which make it feasible for the synthesis of fused polyheterocycles. Moreover, the synthetic manipulation proceeded well with heteroaromatic and aliphatic aldehydes also in good yields.

Computed Properties of C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Rao, RN; Chanda, K or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Heteroleptic copper(I) complexes as energy transfer photocatalysts for the intermolecular [2+2] photodimerization of chalcones, cinnamates and cinnamamides WOS:000650994000030 published article about CYCLOBUTANE; CYCLOADDITION; PHOTOCYCLOADDITION; DERIVATIVES; REDUCTION; FLOW in [Wu, Qing-An; Ren, Chen-Chao; Chen, Feng; Wang, Tian-Qi; Zhang, Yu; Luo, Shu-Ping] Zhejiang Univ Technol, State Key Lab Breeding Base Green Chem Synth Tech, Chaowang Rd 18, Hangzhou 310014, Peoples R China; [Liu, Xue-Fen] Hangzhou Normal Univ, Qianjiang Coll, Hangzhou 310006, Peoples R China; [Chen, Jian-Bin] Qilu Univ Technol, Sch Chem & Chem Engn, Shandong Prov Key Lab Mol Engn, Shandong Acad Sci, Jinan 250353, Peoples R China in 2021.0, Cited 41.0. Formula: C8H8O2. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

The [2 + 2] photodimerization of chalcones, cinnamates and cinnamamides can be effectively catalyzed by heteroleptic copper(I) complexes. The reactions were carried out under mild reaction conditions and the products were obtained in 20-72% yield under visible light irradiation. The copper-based photocatalyst comprised of the rigid phenanthroline ligand with substituents at the 2,9-positions and the 4,7-positions showed high activity in the photodimerization via an energy transfer pathway. (C) 2021 Elsevier Ltd. All rights reserved.

About 4-Methoxybenzaldehyde, If you have any questions, you can contact Wu, QA; Ren, CC; Chen, F; Wang, TQ; Zhang, Y; Liu, XF; Chen, JB; Luo, SP or concate me.. Formula: C8H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Efficient solvent- and temperature-tuned access to aldoxime ethers and phenolic functions by Pd-catalyzed C-O cross-coupling of aldoximes with aryl bromides and bromo-chalcones WOS:000509895700019 published article about ARYLOXIME ETHERS; OXIME ETHERS; PHENYLBORONIC ACIDS; REARRANGEMENT; BENZOFURANS; CYCLIZATION; ARYLATION; DERIVATIVES; COMPLEX in [Reeta; Kaushik, Kumar; Singh, Raj Pal] DRDO, Ctr Fire Explos & Environm Safety, Delhi, India; [Reeta] Univ Delhi, Dept Chem, Delhi, India; [Rangarajan, T. M.; Singh, Rishi Pal] Univ Delhi, Sri Venkateswara Coll, Dept Chem, New Delhi, India; [Singh, Manjula] Univ Delhi, Shivaji Coll, Dept Chem, New Delhi, India in 2020.0, Cited 69.0. HPLC of Formula: C8H8O2. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4

A single method with a functionality switching option was developed for the first time for the Pd-catalyzed C-O cross-coupling of aryl bromides and bromo-chalcones with aldoximes. The ligand tBuXPhos (L2) was found to be an effective supporting ligand for the Pd-catalyzed coupling of aldoximes with bromo coupling partners. The functionality switching from oxime ethers to a phenolic or hydroxy group was driven by solvent or temperature. This method offers the products in good to excellent yields in short reaction times.

HPLC of Formula: C8H8O2. About 4′-Hydroxyacetophenone, If you have any questions, you can contact Reeta; Rangarajan, TM; Kaushik, K; Singh, RP; Singh, M; Singh, RP or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles