Month: November 2021

An article Polyacrylonitrile Nanofibers Incorporating Silver-Decorated Graphitic Carbon Nitride for the Visible-Light-Activated Selective Oxidation of Styrene, Benzylic Methylene Groups, and Benzene WOS:000517856800105 published article about C-H ACTIVATION; CUCR2O4 SPINEL NANOPARTICLES; PHOTOCATALYTIC ACTIVITY; PHOTOCHEMICAL-REACTIONS; AT-RESIN; CATALYST; FABRICATION; MECHANISMS; OXIDE; ESTERIFICATION in [Shah, Akshara P.; Shimpi, Navinchandra G.] Univ Mumbai, Dept Chem, Mumbai 400098, Maharashtra, India; [Sharma, Anuj S.] Gujarat Univ, Sch Sci, Dept Chem, Ahmadabad 380009, Gujarat, India; [Sharma, Vinay S.] Madhav Univ, Fac Basic & Appl Sci, Dept Chem, Pindwara 307026, India in 2020.0, Cited 72.0. Application In Synthesis of 4′-Hydroxyacetophenone. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4

A polyacrylonitrile nanofiber (PAN NF) supported silver nanoparticles-graphitic carbon nitride (Ag NPs/g-C3N4) nanoparticles catalyst was fabricated by electrospinning technique. Structural and morphological studies indicate that the spherical Ag NPs present in the g-C3N4 material were well dispersed on the surfaces of the PAN NFs or embedded in the PAN NFs without agglomerating. The catalytic potential of PAN/Ag NPs/g-C3N4 NFs was developed for oxidation of organic substrate such as styrene, -CH2 bonded molecules, and benzene under visible light. The visible-light-mediated activity of the catalyst could be aided by the photoactive nature of the g-C3N4 surface. PAN/Ag NPs/g-C3N4 NFs show good selectivity toward epoxide with higher conversion (98%) in the case of styrene oxidation. Further, ethylbenzene was oxidized to acetophenone with 99% conversion using H2O2. Additionally, the present material also shows excellent C-H oxidation of benzene (99%) into the desired phenol with higher selectivity. PAN/Ag NPs/g-C3N4 NFs possess mesoporous properties with excellent absorptive performance. This hybrid NFs exhibited enhanced activity, excellent stabilization,and recyclability.

Welcome to talk about 99-93-4, If you have any questions, you can contact Shah, AP; Sharma, AS; Sharma, VS; Shimpi, NG or send Email.. Application In Synthesis of 4′-Hydroxyacetophenone

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Lardy, SW; Luong, KC; Schmidt, VA in WILEY-V C H VERLAG GMBH published article about NICKEL-CATALYZED AMINATION; CROSS-COUPLING REACTIONS; LONG-LIVED CATALYSTS; ONE-POT CONVERSION; C-H AMINATION; ARYL MIGRATION; AROMATIC-COMPOUNDS; METAL; CLEAVAGE; COPPER in [Lardy, Samuel W.; Luong, Kristine C.; Schmidt, Valerie A.] Univ Calif San Diego, Dept Chem & Biochem, 9500 Gilman Dr, La Jolla, CA 92093 USA in 2019, Cited 75. Category: indole-building-block. The Name is 3-(Trifluoromethyl)phenol. Through research, I have a further understanding and discovery of 98-17-9

Phenolic, lignin-derived substrates have emerged as desirable biorenewable chemical feedstocks for coupling reactions. A radical-mediated conversion of phenol derivatives to anilines is reported, using unfunctionalized hydroxamic acids as the N-centered radical source. The applicability of this triethyl phosphite mediated O-atom transfer approach, which tolerates a range of steric and electronic demands to naturally occurring phenols and lignin models, has been demonstrated in this work to access the corresponding aniline derivatives.

Bye, fridends, I hope you can learn more about C7H5F3O, If you have any questions, you can browse other blog as well. See you lster.. Category: indole-building-block

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Application In Synthesis of 3,4-Dimethoxybenzaldehyde. Authors Kumar, M; Joshi, G; Arora, S; Singh, T; Biswas, S; Sharma, N; Bhat, ZR; Tikoo, K; Singh, S; Kumar, R in MDPI published article about in [Kumar, Manvendra; Joshi, Gaurav; Arora, Sahil; Biswas, Sajal; Kumar, Raj] Cent Univ Punjab, Sch Hlth Sci, Dept Pharmaceut Sci & Nat Prod, Lab Drug Design & Synth, Bathinda 151401, Punjab, India; [Joshi, Gaurav] Graph Era Hill Univ, Sch Pharm, Dehra Dun 248171, Uttarakhand, India; [Singh, Tashvinder; Singh, Sandeep] Cent Univ Punjab, Dept Human Genet & Mol Med, Bathinda 151401, Punjab, India; [Sharma, Nisha; Bhat, Zahid Rafiq; Tikoo, Kulbhushan] Natl Inst Pharmaceut Educ & Res, Dept Pharmacol & Toxicol, Sas Nagar 160062, Punjab, India in 2021.0, Cited 33.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

A series of 30 non-covalent imidazo[1,2-a]quinoxaline-based inhibitors of epidermal growth factor receptor (EGFR) were designed and synthesized. EGFR inhibitory assessment (against wild type) data of compounds revealed 6b, 7h, 7j, 9a and 9c as potent EGFR(WT) inhibitors with IC50 values of 211.22, 222.21, 193.18, 223.32 and 221.53 nM, respectively, which were comparable to erlotinib (221.03 nM), a positive control. Furthermore, compounds exhibited excellent antiproliferative activity when tested against cancer cell lines harboring EGFR(WT); A549, a non-small cell lung cancer (NSCLC), HCT-116 (colon), MDA-MB-231 (breast) and gefitinib-resistant NSCLC cell line H1975 harboring EGFR(L858R/T790M). In particular, compound 6b demonstrated significant inhibitory potential against gefitinib-resistant H1975 cells (IC50 = 3.65 mu M) as compared to gefitinib (IC50 > 20 mu M). Moreover, molecular docking disclosed the binding mode of the 6b to the domain of EGFR (wild type and mutant type), indicating the basis of inhibition. Furthermore, its effects on redox modulation, mitochondrial membrane potential, cell cycle analysis and cell death mode in A549 lung cancer cells were also reported.

Application In Synthesis of 3,4-Dimethoxybenzaldehyde. Bye, fridends, I hope you can learn more about C9H10O3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Facile mechanochemical synthesis of Co@NC catalysts for oxidative esterification of benzyl alcohol with methanol WOS:000519664200016 published article about ACTIVE-SITES; SELECTIVE OXIDATION; DISPERSED CO; DOPED CARBON; METAL; EFFICIENT; DEHYDROGENATION; HYDROGENATION; NANOPARTICLES; NANOMATERIALS in [Astrakova, Tatiana, V; Sobolev, Vladimir, I; Koltunov, Konstantin Yu] Russian Acad Sci, Boreskov Inst Catalysis, Pr Akad Lavrentieva 5, Novosibirsk 630090, Russia; [Astrakova, Tatiana, V; Koltunov, Konstantin Yu] Novosibirsk State Univ, Pirogova 2, Novosibirsk 630090, Russia in 2020.0, Cited 35.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6. Computed Properties of C7H8O

A robust and solvent-free mechanochemical approach for the synthesis of cobalt-nitrogen-carbon nanocomposite by simple mixing of cobalt(II) salts, nitrogen-containing ligands and carbon black, followed by thermal treatment is suggested. The catalysts obtained were tested in the oxidative esterification of benzyl alcohol, demonstrating highly competitive performance.

Welcome to talk about 100-51-6, If you have any questions, you can contact Astrakova, TV; Sobolev, VI; Koltunov, KY or send Email.. Computed Properties of C7H8O

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Wang, ZQ; Tang, XS; Yang, ZQ; Yu, BY; Wang, HJ; Sang, W; Yuan, Y; Chen, C; Verpoort, F in [Wang, Zhi-Qin; Wang, Hua-Jing; Sang, Wei; Yuan, Ye; Chen, Cheng; Verpoort, Francis] Wuhan Univ Technol, State Key Lab Adv Technol Mat Synth & Proc, 122 Luoshi Rd, Wuhan 430070, Peoples R China; [Wang, Zhi-Qin; Sang, Wei] Wuhan Univ Technol, Sch Mat Sci & Engn, 122 Luoshi Rd, Wuhan 430070, Peoples R China; [Tang, Xiao-Sheng] Chongqing Univ, Minist Educ, Key Lab Optoelect Technol & Syst, Coll Optoelect Engn, Chongqing 400044, Peoples R China; [Yang, Zhao-Qi] Jiangnan Univ, Sch Pharmaceut Sci, Wuxi 214122, Jiangsu, Peoples R China; [Yu, Bao-Yi] Beijing Agr Univ, Minist Agr, Key Lab Urban Agr North China, Beinong Rd 7, Beijing 102206, Peoples R China; [Verpoort, Francis] Natl Res Tomsk Polytech Univ, Lenin Ave 30, Tomsk 634050, Russia; [Verpoort, Francis] Ghent Univ Global Campus, 119 Songdomunhwa Ro, Incheon 21985, South Korea published Highly active bidentate N-heterocyclic carbene/ruthenium complexes performing dehydrogenative coupling of alcohols and hydroxides in open air in 2019, Cited 45. Recommanded Product: 100-51-6. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.

Eight bidentate NHC/Ru complexes, namely [Ru]-1-[Ru]-8, were designed and prepared. In particular, [Ru]-2 displayed extraordinary performance even in open air for the dehydrogenative coupling of alcohols and hydroxides. Notably, an unprecedentedly low catalyst loading of 250 ppm and the highest TON of 32 800 and TOF of 3200 until now were obtained.

Recommanded Product: 100-51-6. About Benzyl Alcohol, If you have any questions, you can contact Wang, ZQ; Tang, XS; Yang, ZQ; Yu, BY; Wang, HJ; Sang, W; Yuan, Y; Chen, C; Verpoort, F or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Safety of m-Methoxyphenol. Zaitceva, O; Beneteau, V; Ryabukhin, DS; Eliseev, II; Kinzhalov, MA; Louis, B; Vasilyev, AV; Pale, P in [Zaitceva, Olesia; Beneteau, Valerie; Louis, Benoit; Pale, Patrick] Univ Strasbourg, Inst Chim, UMR 7177, CNRS, 4 Rue B Pascal, F-67000 Strasbourg, France; [Eliseev, Ivan I.; Kinzhalov, Mikhal A.; Vasilyev, Aleksander V.] St Petersburg State Univ, 7-9 Univ Skaya Nab, St Petersburg 199034, Russia; [Zaitceva, Olesia; Ryabukhin, Dmitry S.; Vasilyev, Aleksander V.] St Petersburg State Forest Tech Univ, 5 Inst Skii Per, St Petersburg 194021, Russia; [Louis, Benoit] Univ Strasbourg, Inst Chim & Proc Energie Environm & Sante, ECPM, 25 Rue Becquerel, F-67087 Strasbourg 2, France published Cyclization of aryl 3-aryl propynoates into 4-arylcoumarins catalyzed by cyclometalated Platinum(II) complexes in 2020.0, Cited 66.0. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6.

Cyclometalated (ppy)Pt-II complexes (ppy = 2-phenylpyridinato-C-2,N) catalyze the intramolecular cyclization of aryl propynoates to form coumarins and benzocoumarins. The complex [(ppy)PtCl(MeCN)] (5 mol %) was the most active and efficient catalyst for such reaction, especially in the presence of AgSbF6 (15 mol %) in 1,2-dichloroethane. With this catalytic system, a wide range of substituents and functional groups proved compatible with the cyclization process, leading to a large variety of substituted coumarins and benzocoumarins (22 examples, 77-99%) (C) 2020 Elsevier Ltd. All rights reserved.

Safety of m-Methoxyphenol. Bye, fridends, I hope you can learn more about C7H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Synthesis and applications of carbohydrate based chiral ionic liquids as chiral recognition agents and organocatalysts WOS:000512219300036 published article about SODIUM-BOROHYDRIDE REDUCTIONS; CAPILLARY-ELECTROPHORESIS; ENANTIOSEPARATION in [Kaur, Nirmaljeet; Chopra, Harish Kumar] St Longowal Inst Engn & Technol, Dept Chem, Longowal 148106, India in 2020.0, Cited 38.0. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4. Quality Control of 4′-Hydroxyacetophenone

Chiral ionic liquids (CILs) have shown a wide range of applications in variety of domains in chemistry. Because of this, synthesis and applications of CILs have always been areas of interest for research in the last 20 years. Present work describes, the synthesis of six carbohydrate based chiral ionic liquids (CCILs) by following simple procedures and their applications. Structures of the cats were confirmed through various analytical techniques like NMR spectroscopy (H-1, C-13, B-11, P-31,F-19), El-MS, and polarimetry. Designed CCILs were tested as chiral recognising agents using sodium salt of Mosher’s acid as model substrate through (FNMR)-F-19-N- spectroscopy. Further, Cats were used as organocatalyst in the enantioselective reduction of aromatic prochiral ketones to achieve corresponding chiral secondary alcohols. (C) 2019 Elsevier B.V. All rights reserved.

Quality Control of 4′-Hydroxyacetophenone. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Tamuli, KJ; Sahoo, RK; Bordoloi, M in [Tamuli, Kashyap J.; Sahoo, Ranjan K.; Bordoloi, Manobjyoti] CSIR North East Inst Sci & Technol, Chem Sci & Technol Div, Jorhat 785006, Assam, India; [Bordoloi, Manobjyoti] Assam Univ, Dept Chem, Silchar 788011, Assam, India published Biocatalytic green alternative to existing hazardous reaction media: synthesis of chalcone and flavone derivatives via the Claisen-Schmidt reaction at room temperature in 2020.0, Cited 80.0. SDS of cas: 99-93-4. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4.

Owing to the increasing amount of waste materials around the globe, the conversion of waste or secondary by-products to value-added products for various applications has gained significant interest. Herein, two novel agro-food waste products, Musa sp. ‘Malbhog’ peel ash (MMPA) and Musa Champa Hort. ex Hook. F. peel ash (MCPA) are used as catalysts to promote an inexpensive, efficient and eco-friendly carbon-carbon bond forming crossed aldol reaction at room temperature in solvent free conditions. Furthermore, the resulting products were subjected to reactions with these promoters in an oxygen atmosphere and led to the formation of novel flavone derivatives. Moreover, the used catalysts were properly characterized using different sophisticated analytical techniques such as Fourier-transform infrared spectroscopy (FT-IR), X-ray diffractometry (XRD), Brunauer-Emmett-Teller analysis (BET), Raman spectroscopy, scanning electron microscopy energy dispersive X-ray spectroscopy (SEM-EDS), transition electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS) and thermogravimetric analysis (TGA) along with element detection using atomic absorption spectroscopy and ion chromatographic methods. These two approaches are metal free, as well as being devoid of any extra additives, co-catalysts, harsh conditions, the use of column chromatography for purification and result in a higher yield of the product within a short space of time. The catalytic abilities of the promoter were also examined to synthesize important bioactive molecules such as butein and apigenin at room temperature. With gram scale synthesis of the chalcone derivatives, the used catalysts (MMPA and MCPA) were further reused for five cycles and did not demonstrate any loss in catalytic activity.

SDS of cas: 99-93-4. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In 2019.0 ACS CHEM NEUROSCI published article about POTENTIAL ANTICANCER AGENTS; BIOLOGICAL EVALUATION; PATHWAY ACTIVATION; OXIDATIVE STRESS; CURCUMIN; PIPLARTINE; MECHANISMS; INHIBITORS; DISCOVERY; OCCLUSION in [Li, Ge; Zheng, Yuantie; Yao, Jiali; Hu, Linya; Liu, Qunpeng; Ke, Furong; Feng, Weixiao; Zhao, Ya; Yan, Pencheng; He, Wenfei; Qiu, Peihong; Wu, Jianzhang] Wenzhou Med Univ, Sch Pharmaceut Sci, Chem Biol Res Ctr, Wenzhou 325035, Zhejiang, Peoples R China; [Feng, Weixiao; Li, Wulan] Wenzhou Med Univ, Affiliated Hosp 1, Wenzhou 325035, Zhejiang, Peoples R China; [Zhao, Ya; Deng, Hui] Wenzhou Med Univ, Dept Periodont, Hosp & Sch Stomatol, 373 West Xueyuan Rd, Wenzhou 325035, Zhejiang, Peoples R China; [Liu, Qunpeng] Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325035, Zhejiang, Peoples R China in 2019.0, Cited 50.0. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4. Recommanded Product: 3-Hydroxybenzaldehyde

The supplementation of exogenous antioxidants to scavenge excessive reactive oxygen species (ROS) is an effective treatment for cerebral ischemia-reperfusion injury (CIRI) in stroke. Piperlongumine (PL), a natural alkaloid, has a great potential as a neuroprotective agent, but it also has obvious toxicity. Moreover, its neuroprotective effects remain to be improved. In this study, we designed a series of novel PL analogs by hybridizing the screened low-toxicity diketene skeleton with antioxidant effect and the 3,4,5-trimethoxyphenyl group, which may increase the antioxidant activity of PL. The intermediate was synthesized by a novel green synthesis method, and 34 compounds were obtained. The compounds without obvious cytotoxicity have remarkable antioxidant effects, especially compared with diketene skeletons and PL. The cytoprotection of the active compound decreased significantly by reduction of the carbon-carbon double bonds of the Michael acceptor in the diketene skeleton. More importantly, further study revealed that compound A9, which has the best activity, can confer protection for cells against oxidative stress and attenuate brain injury in vivo. Overall, this study provided a promising drug candidate for the treatment of CIRI and guided the further development of drug research in oxidative stress-mediated diseases.

Recommanded Product: 3-Hydroxybenzaldehyde. Bye, fridends, I hope you can learn more about C7H6O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: C8H8O2. Awad, SM; Mohamed, MS; Khodair, MA; Abd El-Hameed, RH in [Awad, Samir M.; Mohamed, Mosaad S.; Khodair, Marwa Abd El-Fattah; Abd El-Hameed, Rania H.] Helwan Univ, Dept Organ Pharmaceut Chem, Fac Pharm, Cairo, Egypt; [Awad, Samir M.] Al Zahrawi Univ Coll, Dept Pharm, Carbalaa, Iraq published Synthesis and Evaluation of Cytotoxic Activity of Certain Benzo[h]chromene Derivatives in 2021.0, Cited 53.0. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

Background: Benzo[h]chromenes attracted great attention because of their widespread biological activities, including anti-proliferate activity, and the discovery of novel effective anti-cancer agents is imperative. Objective: The main objective was to synthesize new benzo[h]chromene derivatives and some reported derivatives, and then test all of them for their anti-cancer activities Methods: The structures of the newly synthesized derivatives were confirmed by elemental and spectral analysis (IR, Mass, H-1-NMR and C-13-NMR). 35 compounds were selected by the National Cancer Institute (NCI) for single-dose testing against 60 cell lines and 3 active compounds were selected for 5-doses testing. Also, these 3 compounds were tested as EGFR-inhibitors; using sorafenib as standard, and as Tubulin polymerization inhibitors using colchicines as a standard drug. Moreover, molecular docking study for the most active derivative on these 2 enzymes was also carried out. Results: Compounds 1a, 1c and 2b have the highest activities among all 35 tested compounds especially compound 1c. Conclusion: compound 1c has promising anti-cancer activities compared to the used standards and may need further modification and investigations.

Welcome to talk about 123-11-5, If you have any questions, you can contact Awad, SM; Mohamed, MS; Khodair, MA; Abd El-Hameed, RH or send Email.. HPLC of Formula: C8H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles