Month: December 2021

Sheet, D; Bera, A; Jana, RD; Paine, TK in [Sheet, Debobrata; Bera, Abhijit; Jana, Rahul Dev; Paine, Tapan Kanti] Indian Assoc Cultivat Sci, Sch Chem Sci, 2A & 2B Raja SC Mullick Rd, Kolkata 700032, India; [Sheet, Debobrata] Presidency Univ, Dept Chem, 86-1 Coll St, Kolkata 700073, India published Oxidizing Ability of a Dioxygen-Activating Nonheme Iron(II)-Benzilate Complex Immobilized on Gold Nanoparticles in 2019.0, Cited 74.0. SDS of cas: 100-51-6. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.

An iron(II)-benzilate complex [(TPASH)Fe-II(benzilate)]ClO4@C8Au (2) (TPASH = 11-((6-((bis(pyridin-2-ylmethyl)amino)methyl)pyridin-2-yl)methoxy)undecane-1-thiol) immobilized on octanethiol stabilized gold nanoparticles (C8Au) of core diameter less than 5 nm has been prepared to evaluate its reactivity toward O-2-dependent oxidations compared to a nonimmobilized complex [(TPA-O-Allyl)Fe-II(benzilate)]ClO4 (1a) (TPA-O-Allyl = N-(6-(allyloxymethyl)pyridin-2-yl)methyl)(pyridin-2-yl)-N-(pyridin-2-ylmethyl)methanamine). X-ray crystal structure of the nonimmobilized complex la reveals a six-coordinate iron(II) center in which the TPA-O-Allyl acts as a pentadentate ligand and the benzilate anion binds in monodentate fashion. Both the complexes (1a and 2) react with dioxygen under ambient conditions to form benzophenone as the sole product through decarboxylation of the coordinated benzilate. Interception studies reveal that a nucleophilic iron-oxygen intermediate is formed in the decarboxylation reaction. The oxidants from both the complexes are able to carry out oxo atom transfer reactions. The immobilized complex 2 not only performs faster decarboxylation but also exhibits enhanced reactivity in oxo atom transfer to sulfides. Importantly, the immobilized complex 2, unlike 1a, displays catalytic turnovers in sulfide oxidation. However, the complexes are not efficient to carry out cis-dihydroxylation of alkenes. Although the immobilized complex yields a slightly higher amount of cis-diol from 1-octene, restricted access of dioxygen and substrates at the coordinatively saturated metal centers of the complexes likely makes the resulting iron-oxygen species less active in oxygen atom transfer to alkenes. The results implicate that surface immobilized nonheme iron complexes containing accessible coordination sites would exhibit better reactivity in O-2-dependent oxygenation reactions.

SDS of cas: 100-51-6. About Benzyl Alcohol, If you have any questions, you can contact Sheet, D; Bera, A; Jana, RD; Paine, TK or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

COA of Formula: C9H10O3. Authors Kulkarni, MR; Lad, NP; Khedkar, VM; Gaikwad, ND in WILEY published article about in [Kulkarni, Mahesh R.; Lad, Nitin P.; Gaikwad, Nitin D.] KRT Arts BH Commerce & AM Sci Coll, Dept Chem, Organ Chem Res Ctr, Gangapur Rd, Nasik 422002, India; [Khedkar, Vijay M.] Vishwakarma Univ, Sch Pharm, Pune, Maharashtra, India in 2021.0, Cited 22.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

With the aim of expanding the scope of SAR on piperlongumine (PL), a naturally occurring anticancer molecule, we have designed a novel hybrid molecule bearing 3,4-dihydroisoquinolin-1(2H)-one and trans-cinnamic acids. The structure, based on hybridization strategy, is used for hybridization of naturally occurring scaffolds. We have synthesized 14 hybrid molecules by coupling 3,4-dihydroisoquinolin-1(2H)-one core with cinnamic acids using the mix anhydride approach. The newly synthesized inhibitors were evaluated for cell viability against breast cancer MCF-7 and cervical cancer HeLa cell lines. Furthermore, the active compounds were screened for their potential in breast cancer MDA-MB-231, cervical cancer C33A cell lines, prostate cancer DU-145, PC-3, and normal VERO cells. From the series, compound 10g was seen to inhibit MCF-7 cell growth significantly with GI(50) < 0.1 mu M along with growth inhibition in MDA-MB-231 (GI(50) = 20 mu M) and C33A (GI(50) = 3.2 mu M). While the inhibitor 10i inhibits MCF-7 breast cancer cell growth GI(50) = 3.42 mu M along with inhibition of cell growth in MDA-MB-231 (GI(50) = 30 mu M), HeLa (GI(50) = 7.67 mu M), C33A (GI(50) = 13 mu M), DU-145 (GI(50) = 6.45 mu M), PC-3 (GI(50) = 8.68 mu M), and VERO (GI(50) = 2.93 mu M), respectively. Furthermore, molecular docking study demonstrated these compounds could bind tightly to the colchicine domain of tubulin through a network of favorable steric and electrostatic interactions and thus act as a tubulin polymerization inhibitor. Welcome to talk about 120-14-9, If you have any questions, you can contact Kulkarni, MR; Lad, NP; Khedkar, VM; Gaikwad, ND or send Email.. COA of Formula: C9H10O3

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Product Details of 123-11-5. I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study published in 2021.0, Reprint Addresses Ibrahim, TS (corresponding author), King Abdulaziz Univ, Fac Pharm, Dept Pharmaceut Chem, Jeddah 21589, Saudi Arabia.; Mohamed, MFA (corresponding author), Sohag Univ, Fac Pharm, Dept Pharmaceut Chem, Sohag 82524, Egypt.. The CAS is 123-11-5. Through research, I have a further understanding and discovery of 4-Methoxybenzaldehyde.

New antibacterial drugs are urgently needed to tackle the rapid rise in multi-drug resistant bacteria. DNA gyrase is a validated target for the development of new antibacterial drugs. Thus, in the present investigation, a novel series of 1,2,4-oxadiazole-chalcone/oxime (6a-f) and (7a-f) were synthesized and characterized by IR, NMR (1H and 13C) and elemental analyses. The title compounds were evaluated for their in-vitro antimicrobial activity by the modified agar diffusion method as well as their E. coli DNA gyrase inhibitory activity. The minimum inhibitory concentration (MIC) and the structure activity relationships (SARs) were evaluated. Among all, compounds 6a, 6c-e, 7b and 7e were the most potent and proved to possess broad spectrum activity against the tested Gram-positive and Gram-negative organisms. Additionally, compounds 6a (against S. aureus), 6c (against B. subtilis and E. hirae), 6e (against E. hirae), 6f, 7a and 7c (against E. coli) and 7d (against B. subtilis), with MIC value of 3.12 mu M were two-fold more potent than the standard ciprofloxacin (MIC = 6.25 mu M). Mechanistically, compounds 6c, 7c, 7e and 7b had good inhibitory activity against E. coli gyrase with IC50 values of 17.05, 13.4, 16.9, and 19.6 mu M, respectively, in comparison with novobiocin (IC50 = 12.3 mu M) and ciprofloxacin (IC50 = 10.5 mu M). The molecular docking results at DNA gyrase active site revealed that the most potent compounds 6c and 7c have binding mode and docking scores comparable to that of ciprofloxacin and novobiocin suggesting their antibacterial activity via inhibition of DNA gyrase. Finally, the predicted parameters of Lipinski’s rule of five and ADMET analysis showed that 6c and 7c had good drug-likeness and acceptable physicochemical properties. Therefore, the hybridization of the chalcone and oxadiazole moieties could be promising lead as antibacterial candidate which merit further future structural optimizations.

Welcome to talk about 123-11-5, If you have any questions, you can contact Ibrahim, TS; Almalki, AJ; Moustafa, AH; Allam, RM; Abuo-Rahma, GEDA; El Subbagh, HI; Mohamed, MFA or send Email.. Product Details of 123-11-5

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Product Details of 100-51-6. Singh, R; Ryu, I; Yadav, H; Park, J; Jo, JW; Yim, S; Lee, JJ in [Singh, Ranbir; Ryu, Ilhwan; Yadav, Hemraj; Park, Jongdeok; Jo, Jea Woong; Lee, Jae-Joon] Dongguk Univ, Res Ctr Photoenergy Harvesting & Convers Technol, Dept Energy Mat & Engn, Seoul 04620, South Korea; [Yim, Sanggyu] Kookmin Univ, Dept Chem, Seoul 02707, South Korea published Non-hydrolytic sol-gel route to synthesize TiO2 nanoparticles under ambient condition for highly efficient and stable perovskite solar cells in 2019.0, Cited 46.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.

For developing low-temperature processed electron-transporting layer in perovskite solar cells, titanium oxide (TiO2) nanoparticle was synthesized through the non-hydrolytic sol-gel route. TiO2 nanoparticles showed uniform film coverage, high transparency in the visible region with wide optical bandgap, and high electrical conductivity after systematically optimizing the synthetic reaction time, the thermal annealing temperature, and the concentration of Nb doping. When TiO2 nanoparticle was introduced as an electron-transporting layer through low-temperature deposition process, the perovskite solar cells fabricated in ambient conditions showed high efficiencies of 18.97% and 13.51% on the rigid glass and the flexible plastic substrate, respectively. An impressively high open circuit voltage of 1.17 V and short circuit current density of 22.21 mA cm(-2) were achieved due to the well aligned work function and better electrical conductivity of Nb-doped LT-TiO2 layer. Importantly, solar cells fabricated with TiO2 nanoparticle showed high thermal stability, negligible hysteresis, and reduced charge recombination loss at electron-transporting layer/perovskite interfaces. This study shows that TiO2 nanoparticle can be obtained through the low cost and facile synthesis and has high potential as an electron-transporting layer for low-temperature processable perovskite solar cells.

Welcome to talk about 100-51-6, If you have any questions, you can contact Singh, R; Ryu, I; Yadav, H; Park, J; Jo, JW; Yim, S; Lee, JJ or send Email.. Product Details of 100-51-6

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Sequential Functionalization of meta-C-H and ipso-C-O Bonds of Phenols WOS:000458348300019 published article about NICKEL-CATALYZED AMINATION; ARYL 2-PYRIDYL ETHERS; ARENES; ACTIVATION; BORYLATION; OLEFINATION; ARYLATION; LIGAND; ALKYLATION; CLEAVAGE in [Xu, Jiancong; Chen, Jingjing; Gao, Feng; Xie, Shuguang; Xu, Xiaohua; Jin, Zhong] Nankai Univ, Coll Chem, State Key Lab, Tianjin 300071, Peoples R China; [Xu, Jiancong; Chen, Jingjing; Gao, Feng; Xie, Shuguang; Xu, Xiaohua; Jin, Zhong] Nankai Univ, Coll Chem, Inst Elementoorgan Chem, Tianjin 300071, Peoples R China; [Xu, Xiaohua; Jin, Zhong] Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China; [Yu, Jin-Quan] Scripps Res Inst, Dept Chem, 10550 North Torrey Pines Rd, La Jolla, CA 92037 USA in 2019, Cited 48. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6. Application In Synthesis of m-Methoxyphenol

The use of a template as a linchpin motif in directed remote C-H functionalization is a versatile yet relatively underexplored strategy. We have developed a template-directed approach to realizing one-pot sequential palladium-catalyzed meta-selective C-H olefination of phenols, and nickel-catalyzed ipso-C-O activation and arylation. Thus, this bifunctional template converts phenols to synthetically useful 1,3-disubstituted arenes.

Bye, fridends, I hope you can learn more about C7H8O2, If you have any questions, you can browse other blog as well. See you lster.. Application In Synthesis of m-Methoxyphenol

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article 3,7-bis-benzylidene hydrazide ciprofloxacin derivatives as promising antiproliferative dual TOP I & TOP II isomerases inhibitors published in 2021. Category: indole-building-block, Reprint Addresses Abdel-Aziz, M (corresponding author), Menia Univ, Fac Pharm, Dept Med Chem, Al Minya 61519, Egypt.; Abuo-Rahma, GEDA (corresponding author), Deraya Univ, Fac Pharm, Dept Pharmaceut Chem, New Minia, Minia, Egypt.. The CAS is 120-14-9. Through research, I have a further understanding and discovery of 3,4-Dimethoxybenzaldehyde

We report herein design and synthesis of a new series of 3,7-bis-benzylidenes of ciprofloxacin. Most of the target compounds revealed good cytotoxic activity; the most potent 4e and 4i achieved strong broad spectrum antiproliferative activity with comparable activity to Doxorubicin with IC50 (M-mu) of 1.21 +/- 0.02, 0.87 +/- 0.04, 1.21 +/- 0.02; 0.41 +/- 0.02, 0.57 +/- 0.06, 1.31 +/- 0.04 and 1.26 +/- 0.01, 1.79 +/- 0.04, 0.63 +/- 0.01 against leukemia cancer cell line HL-60 (TB), colon cancer cell line HCT-116 and breast cancer cell line MCF7, respectively. Moreover, the most potent derivative 4i induced apoptosis at G2/M phase Investigating the mechanism of action of compounds 4e, 4 h and 4i exhibited promising dual TOP I alpha and TOP IIB % inhibition comparable to Camptothecin and Etoposide; respectively. Docking of 4e, 4 h and 4i into the active site of topo I and II proteins compared to Camptothein and Etoposide revealed acceptable binding score and augmented enzyme assay data. Hence, 4e and 4i are promising targeted antiproliferative dual acting TOP I alpha TOP IIB inhibitors that require further optimization.

Welcome to talk about 120-14-9, If you have any questions, you can contact Samir, M; Ramadan, M; Abdelrahman, MH; Abdelbaset, MS; Abourehab, MAS; Abdel-Aziz, M; Abuo-Rahma, GEDA or send Email.. Category: indole-building-block

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Ullah, H; Rahim, F; Taha, M; Hussain, R; Wadood, A; Nawaz, M; Wahab, Z; Kanwal; Khan, KM in BENTHAM SCIENCE PUBL LTD published article about BIOLOGICAL EVALUATION; ANALOGS; ACETYLCHOLINESTERASE; HYDRAZIDE; ETHER in [Ullah, Hayat; Rahim, Fazal; Hussain, Raffaqat; Nawaz, Mohsan] Hazara Univ, Dept Chem, Mansehra 21300, Pakistan; [Taha, Muhammad; Khan, Khalid M.] Imam Abdulrahman Bin Faisal Univ, Inst Res & Med Consultat IRMC, Dept Clin Pharm, POB 31441, Dammam, Saudi Arabia; [Wadood, Abdul] Abdul Wali Khan Univ Mardan, Dept Biochem, Mardan 23200, Pakistan; [Wahab, Zainul] Hazara Univ, Dept Conservat Sci, Mansehra 21300, Pakistan; [Kanwal; Khan, Khalid M.] Univ Karachi, Int Ctr Chem & Biol Sci, HEJ Res Inst Chem, Karachi 75270, Pakistan in 2020.0, Cited 37.0. Product Details of 100-83-4. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4

Background: In the recent past, we have synthesized and repotted different derivatives of oxadiazoles as potential alpha-glucosidase inhibitors, keeping in mind, the pharmacological aspects of oxadiazole moiety and in continuation of our ongoing research on the chemistry and bioactivity of new heterocyclic compounds. Methods: 1,3,4-Oxadiazole derivatives (1-14) have been synthesized and characterized by different spectroscopic techniques such as H-1,-C-1(3)-NMR and HREI-MS. Results: The synthetic derivatives were screened for alpha-glucosidase inhibitory potential. All compounds exhibited good inhibitory activity with IC50 values ranging between 0.80 +/- 0.1 to 45.1 +/- 1.7 mu M in comparison with the standard acarbose having IC50 value 38.45 + 0.80 mu M. Conclusion: Thirteen compounds 1-6 and 8-14 showed potential inhibitory activity as compared to the standard acarbose having IC50 value 38.45 1 0.80 mu M, however, only one compound 7 (IC50 = 45.1 +/- 1.7 mu M) was found to be less active. Compound 14 (IC50 – 0.80 +/- 0.1 mu M) showed promising inhibitory activity among all synthetic derivatives. Molecular docking studies were also conducted for the active compounds to understand the ligand-enzyme binding interactions.

Product Details of 100-83-4. Welcome to talk about 100-83-4, If you have any questions, you can contact Ullah, H; Rahim, F; Taha, M; Hussain, R; Wadood, A; Nawaz, M; Wahab, Z; Kanwal; Khan, KM or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

I found the field of Chemistry very interesting. Saw the article Nucleophile-assisted cyclization of beta-propargylamino acrylic compounds catalyzed by gold(I): a rapid construction of multisubstituted tetrahydropyridines and their fused derivatives published in 2020.0. Name: m-Methoxyphenol, Reprint Addresses Pour, M (corresponding author), Charles Univ Prague, Fac Pharm Hradec Kralove, Dept Organ & Bioorgan Chem, Heyrovskeho 1203, Hradec Kralove 50005, Czech Republic.. The CAS is 150-19-6. Through research, I have a further understanding and discovery of m-Methoxyphenol

Au(I)-catalyzed cyclization of beta-propargylamino acrylic derivatives 1, carried out in the presence of methanol, afforded tetrahydropyridines 3 in high isolated yields. An intramolecular version, using substrates with pending OH, NHBoc and 3-MeOC6H4 groups as internal O-, N-, and C-nucleophiles, yielded the orthofused cyclic derivatives, namely furo[2,3-b]pyridine derivative 14, pyrrolo[2,3-b]pyridine 18, and an unusual chromeno[3,4-c]pyridine 22 with a new quaternary carbon center. Synthetic utilization of the tetrahydropyridines 3 has been demonstrated by their conversion into substances with privileged pharmacophore scaffold. Thus, four 4-aryl piperidine derivatives 23a,b,f,g were obtained on catalytic hydrogenation of the representative 4-aryl tetrahydropyridines 3a,b,f,g; furthermore, the Diels-Alder cycloaddition of dimethyl acetylene dicarboxylate (DMAD) to dienes 3r-3u, possessing a masked dendralene framework, afforded tetrahydroisoquinolines 25r-25u that can be aromatized to produce polysubstituted isoquinolines, as demonstrated by the conversion of 25r into 27r. These domino transformations thus offer numerous variations of this methodology and reveal its potential for synthetic applications.

Name: m-Methoxyphenol. Welcome to talk about 150-19-6, If you have any questions, you can contact Matous, P; Kadanik, M; Timoracky, M; Kunes, J; Marikova, J; Ruzicka, A; Kocovsky, P; Pour, M or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Human Odour Coding in the Yellow Fever Mosquito, Aedes aegypti WOS:000485861500061 published article about ANTENNAL TRICHOID SENSILLA; HUMAN SKIN EMANATIONS; ANOPHELES-GAMBIAE; MALARIA MOSQUITO; OLFACTORY RESPONSES; ATTRACTION; NEURONS; IDENTIFICATION; RECEPTORS; INHIBITION in [Chen, Zhou; Liu, Feng; Liu, Nannan] Auburn Univ, Dept Entomol & Plant Pathol, Auburn, AL 36849 USA in 2019, Cited 45. The Name is (E)-2-Methylbut-2-enoic acid. Through research, I have a further understanding and discovery of 80-59-1. Formula: C5H8O2

Insects use their olfactory systems to obtain chemical information on mating partners, oviposition sites and food. The yellow fever mosquito Aedes aegypti, an important vector of human infectious diseases, shows strong preference for human blood meals. This study investigated the chemical basis of host detection by characterizing the neuronal responses of antenna! olfactory sensilla of female Ae. aegypti to 103 compounds from human skin emanations. The effect of blood feeding on the responses of olfactory sensilla to these odorants was examined as well. Sensilla SBTII, GP, and three functional subtypes of SST (SST1, SST2, and SST3) responded to most of the compounds tested. Olfactory receptor neurons (ORNs) ‘A’ and ‘B’ in the trichoid sensilla, either activated or inhibited, were involved in the odour coding process. Compounds from different chemical classes elicited responses with different temporal structures and different response patterns across the olfactory sensilla. Except for their increased responses to several odorants, blood-fed mosquitoes generally evoked reduced responses to specific aldehydes, alcohols, aliphatics/aromatics, ketones, and amines through the SST1, SST2, SBTI, SBTII and GP sensilla. The odorants eliciting diminished responses in female mosquitoes after blood feeding may be important in Ae. aegypti host-seeking activity and thus can be candidates for mosquito attractants in the process of this disease vector management.

Bye, fridends, I hope you can learn more about C5H8O2, If you have any questions, you can browse other blog as well. See you lster.. Formula: C5H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about IONIC LIQUID; EFFICIENT; CATALYST, Saw an article supported by the Inha University Research Grant. Published in ELSEVIER in AMSTERDAM ,Authors: Taher, A; Lumbiny, BJ; Lee, IM. The CAS is 100-83-4. Through research, I have a further understanding and discovery of 3-Hydroxybenzaldehyde. Computed Properties of C7H6O2

An amine-functionalized metal organic framework (MOF) was used as highly efficient and recyclable heterogeneous catalyst for Knoevenagel condensation of various aromatic aldehydes and ketones in ethanol. The catalytic efficiency was demonstrated by the high conversion of the reactants with 100% selectivity under microwave (mu W) irradiation, while dramatically reduced the reaction time as compared to the conventional heating method. Importantly, the MOF maintained its structural integrity after catalytic reactions and it could be reused several times without remarkable loss of activity.

Computed Properties of C7H6O2. Welcome to talk about 100-83-4, If you have any questions, you can contact Taher, A; Lumbiny, BJ; Lee, IM or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles