Month: January 2022

An article Screening of the Au:Pt Atomic Ratio Supported in SrCO3: Effects in the Performance of the Solvent-Free Oxidation of Benzyl Alcohol WOS:000511995800007 published article about CRYSTALLOGRAPHY OPEN DATABASE; OPEN-ACCESS COLLECTION; SELECTIVE OXIDATION; GOLD NANOPARTICLES; CATALYSTS; METAL; PLATINUM; GLYCEROL; CRYSTAL; OXIDE in [Batista, Francisco S. C. L.; Melo, Itaciara E. M. S.; Pereira, Laise N. S.; Lima, Alexia G. P.; Costa, Jean C. S.; Magalhaes, Janildo L.; Moura, Carla V. R.; Garcia, Marco A. S.; Moura, Edmilson M.] Univ Fed Piaui, Dept Quim, BR-64049550 Teresina, PI, Brazil; [Bashal, Ali H.] Taibah Univ, Fac Sci, Dept Chem, Al Madinah Al Mounawara 30002, Saudi Arabia; [Lima, Francisco C. A.] Univ Fed Piaui, Programa Posgrad Biotecnol RENORBIO, BR-64049550 Teresina, PI, Brazil; [Lima, Francisco C. A.] Univ Estadual Piaui, Lab Quant Computac & Planejamento Farmacos, BR-64002150 Teresina, PI, Brazil in 2020, Cited 46. HPLC of Formula: C7H8O. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6

We have prepared, by a sol-immobilization method, bimetallic catalysts with different Au:Pt atomic ratios supported on commercial SrCO3. The catalytic performance for the oxidation reaction of benzyl alcohol of such materials was compared to the monometallic counterparts. aiming at the obtaining of the best composition of the material. It was found that the Au:Pt atomic ratio presents a remarkable effect on the system performance, i.e., Pt-rich systems arc more selective; however, less active. Thus, an equilibrium related to the activity and selectivity of the system was obtained by considering the yield of the system. Also, some density functional theory (DFT) insights were obtained by using a cluster of 14 atoms of Au and 1 or 2 atoms of Pt. X-ray photoelectron spectroscopy, elemental mapping in scanning transmission electron microscopy before and after catalyst usage, flame atomic absorption spectroscopy, Rietveld refinement, among other techniques, were used and associated to the experimental data, which allowed us to propose a catalytic mechanism for the system, which was important since SiCO3 has not been considered before as catalyst support for alcohol oxidation reactions.

Bye, fridends, I hope you can learn more about C7H8O, If you have any questions, you can browse other blog as well. See you lster.. HPLC of Formula: C7H8O

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: C8H8O2. Recently I am researching about COLCHICINE BINDING; TUBULIN INHIBITORS; COMBRETASTATIN; POTENT; SITE; CHALCONOIDS; CANCER, Saw an article supported by the Research Council of Mazandaran University of Medical Sciences, Sari, Iran [2572]. Published in ACADEMIC PRESS INC ELSEVIER SCIENCE in SAN DIEGO ,Authors: Ansari, M; Shokrzadeh, M; Karima, S; Rajaei, S; Hashemi, SM; Mirzaei, H; Fallah, M; Emami, S. The CAS is 99-93-4. Through research, I have a further understanding and discovery of 4′-Hydroxyacetophenone

Several flexible and rigid analogs of 4H-1,2,4-triazoles (compounds 8a-g and 9a-g) bearing trimethoxyphenyl pharmacophoric unit, were designed and synthesized as potential anticancer agents. The in vitro cytotoxic assay indicated that both flexible and rigid analogs (8 and 9, respectively) can potentially inhibit the growth of cancerous cells (A549, MCF7, and SKOV3), with IC50 values less than 5.0 mu M. Furthermore, compounds 10a-l as regional isomers of compounds 9 exhibited remarkable cytotoxic activity with IC50 values ranging from 0.30 to 5.0 mu M. The rigid analogs 9a, 10h and 10k were significantly more potent than etoposide against MCF7, SKOV3 and A549 cells, respectively. These compounds showed high selectivity towards cancer cells over normal cells, as they had no significant cytotoxicity against L929 cells. In addition, the representative compounds 9a and 10h could inhibit the tubulin polymerization at micro-molar levels. By determining changes in the colchicine-tubulin fluorescence, it was suggested that compound 10h could bind to the tubulin at the colchicine pocket. The molecular docking study further confirmed the inhibitory activity of promising compounds 9a, 10h and 10k on tubulin polymerization through binding to the colchicine-binding site.

HPLC of Formula: C8H8O2. About 4′-Hydroxyacetophenone, If you have any questions, you can contact Ansari, M; Shokrzadeh, M; Karima, S; Rajaei, S; Hashemi, SM; Mirzaei, H; Fallah, M; Emami, S or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region WOS:000592529800004 published article about ACID PHENETHYL ESTER; DRUG DISCOVERY; DERIVATIVES; IMIDAZOLE; INDUCERS; ANALOGS in [Floresta, Giuseppe; Fallica, Antonino N.; Romeo, Giuseppe; Sorrenti, Valeria; Salerno, Loredana; Rescifina, Antonio; Pittala, Valeria] Univ Catania, Dept Drug Sci, Vle Doria 6, I-95125 Catania, Italy; [Floresta, Giuseppe] Kings Coll London, Dept Analyt Environm & Forens, Stamford St, London SE1 9NH, England in 2020.0, Cited 54.0. Formula: C8H8O2. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4

The enzymatic family of heme oxygenase (HO) is accountable for heme breakdown. Among the two isoforms characterized to date, HO-2 is poorly investigated due to the lack of potent HO-2 chemical modulators and the greater attentiveness towards HO-1 isoform. In the present paper, we report the rational design and synthesis of HO-2 inhibitors achieved by modulating the volume of known HO-1 inhibitors. The inhibition preference has been moved from HO-1 to HO-2 by merely increasing the volume of the substituent in the western region of the inhibitors. Docking studies demonstrated that new derivatives soak differently in the two binding pockets, probably due to the presence of a Tyr187 residue in HO-2. These findings could be useful for the design of new selective HO-2 compounds.

Formula: C8H8O2. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Gold(i)-catalyzed nucleophilic cyclization of beta-monosubstituted o-(alkynyl)styrenes: a combined experimental and computational study WOS:000501609000011 published article about CATALYZED CYCLOISOMERIZATION; ENANTIOSELECTIVE SYNTHESIS; DENSITY FUNCTIONALS; GOLD CATALYSIS; 1,5-ENYNES; CARBENE; ALKOXYCYCLIZATIONS; 1,3-DIEN-5-YNES; PERFORMANCE; 1,6-ENYNES in [Virumbrales, Cintia; Solas, Marta; Suarez-Pantiga, Samuel; Fernandez-Rodriguez, Manuel A.; Sanz, Roberto] Univ Burgos, Fac Ciencias, Dept Quim, Area Quim Organ, Pza Misael Banuelos S-N, Burgos 09001, Spain; [Marin-Luna, Marta; Silva Lopez, Carlos] Univ Vigo, Dept Quim Organ, AS Lagoas Marcosende S-N, Vigo 36310, Spain; [Silva Lopez, Carlos] Univ Vigo, CITACA, Orense 32004, Spain; [Fernandez-Rodriguez, Manuel A.] Univ Alcala De Henares, Fac Farm, Dept Quim Organ & Quim Inorgan, Campus Cient Tecnol,Autovia A-2,Km 33-1, Madrid, Spain in 2019, Cited 64. Computed Properties of C7H8O. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6

The stereospecific gold(i)-catalyzed nucleophilic cyclization of beta-monosubstituted o-(alkynyl)styrenes to produce C-1 functionalized 1H-indenes including challenging substrates and nucleophiles, such as beta-(cyclo)alkyl-substituted o-(alkynyl)styrenes and a variety of alcohols as well as selected electron-rich aromatics, is reported. DFT calculations support the stereochemical outcome of the process that involves the formation of a key cyclopropyl gold carbene intermediate through a regiospecific 5-endo cyclization.

Computed Properties of C7H8O. Bye, fridends, I hope you can learn more about C7H8O, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Gomes, LR; Low, JN; Wardell, JL in ELSEVIER published article about in [Gomes, Ligia R.] Univ Fernando Pessoa, FP ENAS Fac Ciencias Saude, Escola Super Saude UFP, Rua Carlos da Maia 296, P-4200150 Porto, Portugal; [Gomes, Ligia R.] Univ Porto, Dept Quim & Bioquim, REQUIMTE, LAQV,Fac Ciencias, Rua Campo Alegre 687, P-4169007 Porto, Portugal; [Low, John N.; Wardell, James L.] Univ Aberdeen, Dept Chem, Meston Walk AB24 3UE, Old Aberdeen, Scotland; [Wardell, James L.] Fundacao Oswaldo Cruz, Inst Tecnol Farmacos & Farmanguinhos, BR-21041250 Rio De Janeiro, RJ, Brazil in 2021, Cited 33. Recommanded Product: 4-Methoxybenzaldehyde. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

The crystal structures, Hirshfeld surface analysis and PIXEL calculations are reported for (E)-3-(4-methoxyphenyl)-1-(2-hydroxy-5-isoproproxyphenyl)prop-2-en-1-one, 1, and (E)-3-(3-methoxy-4-isopropoxyphenyl)-1-(2-hydroxy-4,6-diisoproproxyphenyl)prop-2-en-1-one, 2. Different sets of C-H…O, C-H…pi, off-set, face-to-face pi…pi and/or C=O…pi intermolecular interactions are displayed by each compound. Due to the bulk of the isoproproxy unit and the consequent steric hindrance in forming aggregates in the solid state, compounds 1 and 2 exhibit larger interplanar angles than do corresponding chalcones with methoxy units. The total stabilization energies of the crystal packing, E-tot distributed as Coulombic (E-coul), polarization (E-pol), dispersion (E-disp), and repulsion (E-rep) have been computed by PIXEL. For compound 1, six motifs (molecule pairs) and for compound 2, with two independent molecules in the asymmetric unit, thirteen motifs are identified by the PIXEL calculations to have energies, -E-tot, above the cut-offvalue of 10 kJ.mol(-1). For each of these motifs, the largest contributor to the E-tot value is the E-disp term, irrespective of the type(s) of interaction(s) connecting the two molecules, if any, in the motifs. (C) 2021 Elsevier B.V. All rights reserved.

Welcome to talk about 123-11-5, If you have any questions, you can contact Gomes, LR; Low, JN; Wardell, JL or send Email.. Recommanded Product: 4-Methoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Name: Benzyl Alcohol. Recently I am researching about VOLATILES, Saw an article supported by the New Zealand Institute for Plant & Food Research by Core Funding (Viticulture Sector) from the Ministry of Business Innovation and Employment; New Zealand Institute for Plant & Food Research by Core Funding (Better Border Biosecurity) from the Ministry of Business Innovation and Employment. Published in WALTER DE GRUYTER GMBH in BERLIN ,Authors: El-Sayed, AM; Sporle, A; Gemeno, C; Josvai, JK; Simmons, GS; Suckling, DM. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol

We recently identified unique caterpillar-induced plant volatile compounds emitted from apple leaves infested with the larvae of various leafroller species. In subsequent field tests, binary blends of phenylacetonitrile + acetic acid and 2-phenylethanol +acetic acid were found to be attractive to a range of tortricid leafroller species (Tortricidae: Tortricinae) in both the Southern and Northern Hemispheres. In this work, the caterpillar-induced plant volatiles from the apple-leafroller system were tested in two vineyards in Spain and Hungary for their attractiveness to the grape frugivore Lobesia botrana (Tortricidae: Olethreutinae). As seen for Tortricinae species, a binary blend of phenylacetonitrile +acetic acid attracted significantly more male and female L. botrana to traps than acetic acid or blank lures. Traps baited with other caterpillar-induced plant volatile compounds (benzyl alcohol, 2-phenylethanol, indole, and (E)-nerolidol, each as a binary blend with acetic acid) did not catch significantly more moths than traps containing acetic acid alone. The catches of male and female moths support an optimistic future for new products in female tortricid surveillance and control that are based on combinations of kairomone compounds released from larval-damaged foliage.

Welcome to talk about 100-51-6, If you have any questions, you can contact El-Sayed, AM; Sporle, A; Gemeno, C; Josvai, JK; Simmons, GS; Suckling, DM or send Email.. Name: Benzyl Alcohol

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Adamek, J; Zielezny, P; Erfurt, K in [Adamek, Jakub; Zielezny, Paulina] Silesian Tech Univ, Dept Organ Chem Bioorgan Chem & Biotechnol, PL-44100 Gliwice, Poland; [Erfurt, Karol] Silesian Tech Univ, Dept Chem Organ Technol & Petrochem, PL-44100 Gliwice, Poland; [Adamek, Jakub] Silesian Tech Univ, Biotechnol Ctr, PL-44100 Gliwice, Poland published Synthesis of N-Protected 1-Aminoalkylphosphonium Salts from Amides, Carbamates, Lactams, or Imides in 2021.0, Cited 39.0. Quality Control of 4-Methoxybenzaldehyde. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

This report describes the development and optimization of the one-pot method for the synthesis of N-protected 1-aminoalkylphosphonium salts based on the three-component coupling of aldehydes and either amides, carbamates, lactams, imides, or urea in the presence of triarylphosphonium salts. The proposed strategy is very efficient and easy to carry out even on a larger scale (20 g) in any typical laboratory. Most reactions occur at temperatures between 50 and 100 degrees C in a short time (1-2 h) without requiring any catalyst, and simple workup procedures afford good to excellent yields. The exceptions are condensations with imides, which require much higher temperatures (150-170 degrees C) and longer reaction times (even 30 h). The possibility of carrying out the synthesis under solvent-free conditions (neat reactions) is also demonstrated. It is especially important for less reactive substrates (imides), and reactions required high temperature (or generally harsher conditions). Finally, we prove the developed one-pot methodology can be successfully applied for the synthesis of structurally diverse N-protected 1-aminoalkylphosphonium salts. Mechanistic studies showed the intermediate products of described couplings are 1-hydroxyalkylphosphonium salts, not N-hydroxyalkylamides, -imides, etc., as initially expected.

Quality Control of 4-Methoxybenzaldehyde. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Adamek, J; Zielezny, P; Erfurt, K or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Selective synthesis of 1-halonaphthalenes by copper-catalyzed benzannulation WOS:000604923900027 published article about REGIOSELECTIVE SYNTHESIS; NAPHTHALENE DERIVATIVES; O-ALKYNYLBENZALDEHYDES; PLATINUM(II)-CATALYZED REACTION; CARBONYL-COMPOUNDS; ALKYNES; ANNULATION; ETHERS; 2-ALKYNYLBENZOATES; FUNCTIONALIZATION in [Umeda, Rui; Ueda, Ryo; Tanaka, Taiki; Hayashi, Akitsugu; Nishiyama, Yutaka] Kansai Univ, Fac Chem Mat & Bioengn, Suita, Osaka 5648680, Japan; [Ikeshita, Masahiro; Suzuki, Shuichi; Naota, Takeshi] Osaka Univ, Grad Sch Engn Sci, Dept Chem, Toyonaka, Osaka 5608531, Japan in 2021.0, Cited 48.0. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5. Computed Properties of C7H8O2

The synthesis of 1-halonaphthalenes by the Cu-catalyzed benzannulation reaction of 2-(phenylethynyl) benzaldehyde and alkynes in the presence of the halogen reagents such as NBS, NCS, and NIS, was developed. This protocol afforded various type of 1-halonaphthalenes in moderate to excellent yields and the cross coupling reactions of 1-bromo-2-phenylnaphthalene prepared by this method with various reagents occurred to give the corresponding 1,2-disubstituted naphthalenes. (C) 2020 Elsevier Ltd. All rights reserved.

Welcome to talk about 150-76-5, If you have any questions, you can contact Umeda, R; Ueda, R; Tanaka, T; Hayashi, A; Ikeshita, M; Suzuki, S; Naota, T; Nishiyama, Y or send Email.. Computed Properties of C7H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 123-11-5. Authors Yang, GP; Li, K; Zeng, K; Li, YJ; Yu, T; Liu, YF in ROYAL SOC CHEMISTRY published article about in [Yang, Guoping; Li, Ke; Zeng, Kai; Li, Yijin; Liu, Yufeng] East China Univ Technol, Jiangxi Prov Key Lab Synthet Chem, Nanchang 330013, Jiangxi, Peoples R China; [Yu, Tao] East China Univ Technol, Sch Nucl Sci & Engn, Nanchang 330013, Jiangxi, Peoples R China in 2021.0, Cited 45.0. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

A recyclable and efficient heterogeneous, green catalyst based on the synthesis of Keggin-type polyoxometalate (H3PMo12O40) and vitamin B1 analogue 3-ethyl-5-(2-hydroxyethyl)-4-methylthiazol-3-ium (HEMT), i.e., [HEMTH]H-2[PMo12O40] was prepared. Oxa-Pictet-Spengler cyclization of arylethanols and aldehydes were catalyzed to afford various substituted isochromans in moderate conditions with excellent yields using dimethyl carbonate (DMC) as a green solvent. Furthermore, this protocol was applicable in a gram-scale reaction, and the catalyst could be recycled eight times without significant loss of activity.

SDS of cas: 123-11-5. Welcome to talk about 123-11-5, If you have any questions, you can contact Yang, GP; Li, K; Zeng, K; Li, YJ; Yu, T; Liu, YF or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: C9H10O3. In EUR GERIATR MED published article about EYE CATARACT-SURGERY; SELF-REPORTED VISION; RISK-FACTORS; OLDER-ADULTS; VISUAL IMPAIRMENT; PEOPLE; WOMEN; PREDICTOR; INJURIES; FRAILTY in [Ogliari, Giulia; Masud, Tahir] Nottingham Univ Hosp NHS Trust, Queens Med Ctr, Dept Hlth Care Older People HCOP, Derby Rd, Nottingham NG7 2UH, Notts, England; [Ryg, Jesper; Andersen-Ranberg, Karen; Masud, Tahir] Odense Univ Hosp, Dept Geriatr Med, Sdr Blvd 29, DK-5000 Odense, Denmark; [Ryg, Jesper; Andersen-Ranberg, Karen] Univ Southern Denmark, Dept Clin Res, Geriatr Res Unit, Sdr Blvd 29, DK-5000 Odense, Denmark; [Qureshi, Nadeem] Univ Nottingham, Sch Med, Div Primary Care, Nottingham, England; [Andersen-Ranberg, Karen; Scheel-Hincke, Lasse Lybecker] Univ Southern Denmark, Dept Publ Hlth, Epidemiol Biostat & Biodemog, JB Winslowvej 9B, DK-5000 Odense, Denmark in , Cited 48.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9.

Purpose To investigate the association between vision and hearing impairment and falls in community-dwelling adults aged >= 50 years. Methods This is a prospective study on 50,986 participants assessed in Waves 6 and 7 of the Survey of Health, Ageing and Retirement in Europe. At baseline, we recorded socio-demographic data, clinical factors and self-reported vision and hearing impairment. We classified participants as having good vision and hearing, impaired vision, impaired hearing or impaired vision and hearing. We recorded falls in the six months prior to the baseline and 2-year follow-up interviews. The cross-sectional and longitudinal associations between vision and hearing impairment categories and falls were analysed by binary logistic regression models; odds ratios (OR) and 95% confidence intervals (CI) were calculated. All analyses were adjusted for socio-demographic and clinical factors. Results Mean age was 67.1 years (range 50-102). At baseline, participants with impaired vision, impaired hearing, and impaired vision and hearing had an increased falls risk (OR (95% CI)) of 1.34 (1.22-1.49), 1.34 (1.20-1.50) and 1.67 (1.50-1.87), respectively, compared to those with good vision and hearing (all p < 0.001). At follow-up, participants with impaired vision, without or with impaired hearing, had an increased falls risk of 1.19 (1.08-1.31) and 1.33 (1.20-1.49), respectively, compared to those with good vision and hearing (both p < 0.001); hearing impairment was longitudinally associated with falls in middle-aged women. Conclusion Vision impairment was cross-sectionally and longitudinally associated with an increased falls risk. This risk was highest in adults with dual sensory impairment. Key summary pointsAim To investigate the relationship between self-reported vision and hearing impairment and falls risk in community-dwelling adults aged >= 50 years in the cross-national Survey of Health, Ageing and Retirement in Europe (SHARE). Findings Self-reported vision impairment, versus no impairment, was cross-sectionally and longitudinally associated with an increased falls risk in adults, independent of age, sex, self-rated health, co-morbidities and medications. The risk was highest when vision and hearing impairment coincided. Message Simple questions on self-reported sensory impairment can be used to assess the risk of falls in adults.

HPLC of Formula: C9H10O3. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Ogliari, G; Ryg, J; Qureshi, N; Andersen-Ranberg, K; Scheel-Hincke, LL; Masud, T or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles