Day: February 9, 2022

Safety of Mequinol. In 2021 NAT COMMUN published article about PHOTODYNAMIC THERAPY; ACTIVATABLE PHOTOSENSITIZER; DERIVATIVES; U87 in [Benson, Sam; de Moliner, Fabio; Fernandez, Antonio; Bravo, Isabel R.; Elliot, Abigail M.; Feng, Yi; Vendrell, Marc] Univ Edinburgh, Queens Med Res Inst, Ctr Inflammat Res, Edinburgh, Midlothian, Scotland; [Kuru, Erkin] Harvard Med Sch, Dept Genet, Boston, MA 02115 USA; [Kuru, Erkin] Wyss Inst Biol Inspired Engn, Boston, MA USA; [Asiimwe, Nicholas L.] Korea Inst Sci & Technol KIST, Mol Recognit Res Ctr, Seoul, South Korea; [Asiimwe, Nicholas L.] UST, KIST Sch, Biomed Program, Seoul, South Korea; [Lee, Jun-Seok] Korea Univ, Dept Pharmacol, Coll Med, Seoul, South Korea; [Hamilton, Lloyd; Sieger, Dirk] Univ Edinburgh, Ctr Discovery Brain Sci, Edinburgh, Midlothian, Scotland in 2021, Cited 63. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5.

Metabolites can distinguish pathogenic from healthy cells, but they are hard to couple to current photosensitizers without altering their biological activity. Here the authors design a new family of photosensitizers that retain metabolite function to target pathogenic cells and ablate them by photodynamic therapy. Photoactivatable molecules enable ablation of malignant cells under the control of light, yet current agents can be ineffective at early stages of disease when target cells are similar to healthy surrounding tissues. In this work, we describe a chemical platform based on amino-substituted benzoselenadiazoles to build photoactivatable probes that mimic native metabolites as indicators of disease onset and progression. Through a series of synthetic derivatives, we have identified the key chemical groups in the benzoselenadiazole scaffold responsible for its photodynamic activity, and subsequently designed photosensitive metabolic warheads to target cells associated with various diseases, including bacterial infections and cancer. We demonstrate that versatile benzoselenadiazole metabolites can selectively kill pathogenic cells – but not healthy cells – with high precision after exposure to non-toxic visible light, reducing any potential side effects in vivo. This chemical platform provides powerful tools to exploit cellular metabolic signatures for safer therapeutic and surgical approaches.

Welcome to talk about 150-76-5, If you have any questions, you can contact Benson, S; de Moliner, F; Fernandez, A; Kuru, E; Asiimwe, NL; Lee, JS; Hamilton, L; Sieger, D; Bravo, IR; Elliot, AM; Feng, Y; Vendrell, M or send Email.. Safety of Mequinol

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Iron-Promoted Synthesis of (2-Oxy/Thio)benzothiazole WOS:000594505700026 published article about COPPER(I)-CATALYZED CASCADE SYNTHESIS; OXIDATION-REDUCTION CONDENSATION; CROSS-COUPLING REACTIONS; ALKYL ARYL SULFIDES; S BOND FORMATION; C-S; ELEMENTAL SULFUR; SUBSTITUTED BENZOTHIAZOLES; NUCLEOPHILIC-SUBSTITUTION; HIGHLY EFFICIENT in [Parvathi, Edalada Venkata Krishna; Rudraraju, Ramesh Raju] Acharya Nagarjuna Univ, Dept Chem, Guntur 522510, Andhra Pradesh, India; [Pinapati, Srinivasa Rao] SVRM Coll, Dept Chem, Nagaram 522268, Andra Pradesh, India; [Tamminana, Ramana] GITAM Deemed Univ, Dept Chem, Nagadenahalli 562163, Karnataka, India in 2020.0, Cited 97.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6. Computed Properties of C7H8O

The synthesis of (2-Phenoxy)benzothiazole and (2-Phenylthio)benzothiazole has been demonstrated in the presence of iron catalyst under mild reaction conditions. Library of target compounds are prepared under optimized reaction conditions. Both electron donating and electron withdrawing substituent’s are readily carried out the reaction to provide their respective target products in moderate to good yield. Mechanistic studies have suggested that the methodology involves intra molecular C-S cross-coupling approach.

Computed Properties of C7H8O. Welcome to talk about 100-51-6, If you have any questions, you can contact Parvathi, EVK; Pinapati, SR; Tamminana, R; Rudraraju, RR or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about RESISTANT STAPHYLOCOCCUS-AUREUS; SOFT ACIDS; HARDNESS; ELECTRONEGATIVITY; COMBINATION; MECHANISM, Saw an article supported by the Fundacao Cearense de Apoio ao Desenvolvimento Cientifico e Tecnologico – FUNCAPFundacao Cearense de Apoio ao Desenvolvimento Cientifico e Tecnologico (FUNCAP) [BP2-0107- 00026.01.00/15, BP4-00172-00017.01.00/20, BP4-00172-00065.01.01/20]; Conselho Nacional de Desenvolvimento Cientifico e Tecnologico – CNPqConselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ) [305719/2018-1]; Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior – CAPESCoordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) [001]; program of the government of India – Research Training Fellowship for Developing Country Scientist (RTF- DCS) [DCS/2019/000192]. Published in ELSEVIER in AMSTERDAM ,Authors: Xavier, JD; de Almeida-Neto, FWQ; Rocha, JE; Freitas, TS; Freitas, PR; de Araujo, ACJ; da Silva, PT; Nogueira, CES; Bandeira, PN; Marinho, MM; Marinho, ES; Kumar, N; Barreto, ACH; Coutinho, HDM; Juliao, MSS; dos Santos, HS; Teixeira, AMR. The CAS is 123-11-5. Through research, I have a further understanding and discovery of 4-Methoxybenzaldehyde. Computed Properties of C8H8O2

Six 2′-hydroxychalcones were synthesized and characterized by NMR, FT-Raman, ATR-FTIR, and UV-Vis. These chalcones alone and in combination with the ciprofloxacin, penicillin, and erythromycin antibiotics were tested against multiresistant strains of Staphylococcus aureus. It was also verified by in vitro and in silico studeis the capacity of these chalcones to inhibit the NorA efflux pump. The MICs values of ciprofloxacin were reduced in the presence of all tested chalcones. For norfloxacin antibiotic, the chalcones A1, A4, A5 and A6 promoted the reduced in the MIC values. The A2 chalcone was the only one to reduce the MIC values when associated with penicillin. Any chalcones were not able to reduce MIC values when associated with erythromycin. These results indicate that the synergistic effects demonstrated for the synthesized chalcones were influenced by the introduction of a furanic ring (A1), a chlorine atom and a methoxy group at the C4 position (A2 and A4), a second double bond (A5), and a fluorine atom at the C2 position (A6). The ADMET analysis predicts that the chalcones A2, A3, A5 and A6 have easier cell permeation. The nucleophilic region makes the A5 chalcone capable of covalently bonding with plasma proteins, and the presence of oxygenated aromatic substitutions makes the chalcones A1 and A4 more water-soluble and consequently easier to excrete. On the other hand, the substitution of the methoxy group of the A4 chalcone makes it more susceptible to O-demethylation reactions by the CYP3A4 isoenzyme. The molecular docking revealed that all six chalcones could hinder the binding of norfloxacin to the NorA efflux pump. (c) 2021 Elsevier B.V. All rights reserved.

Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.. Computed Properties of C8H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Molecular docking, pharmacokinetic studies, and in vivo pharmacological study of indole derivative 2-(5-methoxy-2-methyl-1H-indole-3-yl)-N ‘-[(E)-(3-nitrophenyl) methylidene] acetohydrazide as a promising chemoprotective agent against cisplatin induced organ damage WOS:000667581800045 published article about ALPHA-LIPOIC ACID; NF-KAPPA-B; INDUCED NEPHROTOXICITY; INDUCED HEPATOTOXICITY; OXIDATIVE STRESS; STAT3; ANTIOXIDANT; DESIGN; INTERLEUKIN-6; CYTOKINES in [Razak, Suhail; Afsar, Tayyaba; Abulmeaty, Mahmoud; Almajwal, Ali; Al Disi, Dara] King Saud Univ, Coll Appl Med Sci, Dept Community Hlth Sci, Riyadh, Saudi Arabia; [Bibi, Nousheen; Inam, Anam] Shaheed Benazir Bhutto Women Univ, Dept Bioinformat, Peshawar, Pakistan; [Qamar, Wajhul] King Saud Univ, Coll Pharm, Dept Pharmocol & Toxicol, Cent Lab, Riyadh 11451, Saudi Arabia; [Bhat, Mashooq Ahmad] King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, Riyadh 11451, Saudi Arabia; [Shabbir, Maria] Natl Univ Sci & Technol, Atta Ur Rahman Sch Appl Biosci, Islamabad, Pakistan in 2021.0, Cited 76.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9. COA of Formula: C9H10O3

Cisplatin is an efficient anticancer drug against various types of cancers however, its usage involves side effects. We investigated the mechanisms of action of indole derivative, 2-(5-methoxy-2-methyl-1H-indol-3-yl)-N’-[(E)-(3-nitrophenyl) methylidene] acetohydrazide (MMINA) against anticancer drug (cisplatin) induced organ damage using a rodent model. MMINA treatment reversed Cisplatin-induced NO and malondialdehyde (MDA) augmentation while boosted the activity of glutathione peroxidase (GPx), and superoxide dismutase (SOD). The animals were divided into five groups (n=7). Group1: Control (Normal) group, Group 2: DMSO group, Group 3: cisplatin group, Group 4: cisplatin+MMINA group, Group 5: MMINA group. MMINA treatment normalized plasma levels of biochemical enzymes. We observed a significant decrease in CD4(+)COX-2, STAT3, and TNF-alpha cell population in whole blood after MMINA dosage. MMINA downregulated the expression of various signal transduction pathways regulating the genes involved in inflammation i.e. NF-kappa B, STAT-3, IL-1, COX-2, iNOS, and TNF-alpha. The protein expression of these regulatory factors was also downregulated in the liver, kidney, heart, and brain. In silico docking and dynamic simulations data were in agreement with the experimental findings. The physiochemical properties of MMINA predicted it as a good drug-like molecule and its mechanism of action is predictably through inhibition of ROS and inflammation.

COA of Formula: C9H10O3. Welcome to talk about 120-14-9, If you have any questions, you can contact Razak, S; Afsar, T; Bibi, N; Abulmeaty, M; Qamar, W; Almajwal, A; Inam, A; Al Disi, D; Shabbir, M; Bhat, MA or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: 86-95-3. In 2019 MOLECULES published article about FLUOROQUINOLONES; DERIVATIVES; INHIBITORS; MECHANISM; DESIGN; SIGNAL in [Aly, Ashraf A.; Hassan, Alaa A.; Mohamed, Nasr K.; Abd El-Haleem, Lamiaa E.] Menia Univ, Fac Sci, Chem Dept, El Minia 61519, Egypt; [Braese, Stefan] Karlsruhe Inst Technol, Inst Organ Chem, D-76131 Karlsruhe, Germany; [Braese, Stefan] Karlsruhe Inst Technol, Inst Toxicol & Genet, D-76344 Eggenstein Leopoldshafen, Germany; [Polamo, Mika; Nieger, Martin] Univ Helsinki, Dept Chem, POB 55,AI Virtasen Aukio 1, Helsinki 00014, Finland; [Brown, Alan B.] Florida Inst Technol, Chem Program, Melbourne, FL 32901 USA in 2019, Cited 31. The Name is 4-Hydroxyquinolin-2(1H)-one. Through research, I have a further understanding and discovery of 86-95-3.

Herein, we report the synthesis of 5,12-dihydropyrazino[2,3-c:5,6-c ‘]difuro[2,3-c:4,5-c ‘]-diquinoline-6,14(5H,12H)diones, 2-(4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-1,4-diphenyl- butane-1,4-diones and 4-(benzo-[d]oxazol-2-yl)-3-hydroxy-1H-[4,5]oxazolo[3,2-a]pyridine-1-one. The new candidates were synthesized and identified by different spectroscopic techniques, and X-ray crystallography.

Bye, fridends, I hope you can learn more about C9H7NO2, If you have any questions, you can browse other blog as well. See you lster.. Recommanded Product: 86-95-3

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article High-efficient synthesis of 2-imino-2H-chromenes and dihydropyrano[c]chromenes using novel and green catalyst (CaO@SiO2@AIL) WOS:000578875700001 published article about ONE-POT SYNTHESIS; 3-COMPONENT SYNTHESIS; CHROMENE DERIVATIVES; MULTICOMPONENT; MALONONITRILE; NANOPARTICLES; BISCOUMARIN; RECOVERY; WASTE in [Sameri, Fatemeh; Mobinikhaledi, Akbar; Bodaghifard, Mohammad Ali] Arak Univ, Fac Sci, Dept Chem, Arak 3815688138, Iran; [Sameri, Fatemeh; Mobinikhaledi, Akbar; Bodaghifard, Mohammad Ali] Arak Univ, Inst Nanosci & Nanotechnol, Arak 3815688138, Iran in 2021, Cited 54. Safety of 3-Hydroxybenzaldehyde. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4

In this work, 1,3,5,7-tetraazaadamantan-1-ium chloride (AIL) functionalized silica-coated calcium oxide hybrid nanocatalyst (CaO@SiO2@AIL) as a novel, efficient, green and recyclable heterogeneous ionic liquid catalyst was synthesized. Catalytic activity of the CaO@SiO2@AIL hybrid nanoparticles was investigated for synthesis of the pharmaceutically valuable 2-imino-2H-chromene and dihydropyrano[c]chromene derivatives. A wide range of amines and aromatic aldehydes containing either electron-withdrawing or electron-donating substituent were examined using optimized conditions to produce the desired products. 2-Imino-2H-chromenes were synthesized under solvent-free condition, and dihydropyrano[c]chromenes were prepared in aqueous medium as green conditions within short reaction times, high yields and using easy workup procedures. Structure confirmation and surface properties of the core/shell hybrid nanoparticles were considered via Fourier transform infrared spectroscopy, X-ray powder diffraction, scanning electron microscope, energy-dispersive X-ray spectroscopy, WDS map scan, thermogravimetric and elemental analyses. This IL-supported heterogeneous nanocatalyst can be reused at least six times without considerable loss of its performance.

Welcome to talk about 100-83-4, If you have any questions, you can contact Sameri, F; Mobinikhaledi, A; Bodaghifard, MA or send Email.. Safety of 3-Hydroxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about ALKENE HYDROGENATION; GRIGNARD-REAGENTS; COBALT; METAL; TEMPERATURE; SCOPE, Saw an article supported by the European Research CouncilEuropean Research Council (ERC)European Commission [CoG 683150]; University of Hamburg. Product Details of 80-59-1. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Bernauer, J; Wu, GJ; Jacobi von Wangelin, A. The CAS is 80-59-1. Through research, I have a further understanding and discovery of (E)-2-Methylbut-2-enoic acid

An iron-catalysed allylation of organomagnesium reagents (alkyl, aryl) with simple allyl acetates proceeds under mild conditions (Fe(OAc)(2) or Fe(acac)(2), Et2O, r.t.) to furnish various alkene and styrene derivatives. Mechanistic studies indicate the operation of a homotopic catalyst. The sequential combination of such iron-catalysed allylation with an iron-catalysed hydrogenation results in overall C(sp(3))-C(sp(3))-bond formation that constitutes an attractive alternative to challenging direct cross-coupling protocols with alkyl halides.

Product Details of 80-59-1. About (E)-2-Methylbut-2-enoic acid, If you have any questions, you can contact Bernauer, J; Wu, GJ; Jacobi von Wangelin, A or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Synthesis, characterization and antichagasic evaluation of thiosemicarbazones prepared from chalcones and dibenzalacetones WOS:000632867700003 published article about CHAGAS-DISEASE; BENZNIDAZOLE; POSACONAZOLE; CHALLENGES; COMPLEXES; DESIGN in [da Silva, Aline Alves; Valle, Marcelo Siqueira] Univ Fed Sao Joao Del Rei, Dept Ciencias Nat, BR-36301160 Sao Joao Del Rei, MG, Brazil; [Maia, Pedro Ivo da Silva] Univ Fed Triangulo Mineiro, Dept Quim, BR-38025440 Uberaba, MG, Brazil; [Lopes, Carla Duque; de Albuquerque, Sergio] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Dept Anal Clin Toxicol & Bromatol, Ave Cafes S-N, BR-14040903 Ribeirao Preto, SP, Brazil; [Lopes, Carla Duque; de Albuquerque, Sergio] Univ Sao Paulo, USP, FCFRP, Ave Cafes S-N, BR-14040903 Ribeirao Preto, SP, Brazil; [Lopes, Carla Duque] Ctr Univ Estacio Ribeirao Preto, Abraao Issa Halach St 980, BR-14096160 Ribeirao Preto, SP, Brazil in 2021, Cited 28. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9. COA of Formula: C9H10O3

Chagas disease is a neglected disease, being one of the leading causes of death from infectious diseases. In view of the severity of this pathology, this work describes the synthesis of new thiosemicarbazones derived from chalcones and dibenzalacetones as potential drugs for the treatment of this disease. The structures of all compounds were elucidated by infrared (IR) and nuclear magnetic resonance (H-1 and C-13 NMR) spectroscopies. The chalcone derived thiosemicarbazones 10-14 were tested against the intracellular amastigote form of the protozoan Trypanosoma cruzi and had their cytotoxicity assessed using LLC-MK2 cells. The compound 10 (IC50 = 12.25 mu M) presented the best activity when compared with the standard drug benznidazole (IC50 = 5.64 mu M). (C) 2021 Elsevier B.V. All rights reserved.

COA of Formula: C9H10O3. Bye, fridends, I hope you can learn more about C9H10O3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Experimental and Computational Studies of Palladium-Catalyzed Spirocyclization via a Narasaka-Heck/C(sp(3) or sp(2))-H Activation Cascade Reaction WOS:000657212800032 published article about C-H ALKYLATION; ARYLATION; FUNCTIONALIZATION; CONSTRUCTION; CYCLIZATION; ALKENES; ARENES in [Wei, Wan-Xu; Wen, Ya-Ting; Li, Ming; Li, Xue-Song; Wang, Cui-Tian; Liu, Hong-Chao; Jiao, Rui-Qiang; Liang, Yong-Min] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China; [Li, Yuke] Chinese Univ Hong Kong, Dept Chem, Shatin, Hong Kong, Peoples R China; [Li, Yuke] Chinese Univ Hong Kong, Ctr Sci Modeling & Computat, Shatin, Hong Kong, Peoples R China; [Xia, Yu] Xinjiang Univ, Coll Chem, Urumqi Key Lab Green Catalysis & Synth Technol, Urumqi 830046, Peoples R China; [Zhang, Bo-Sheng] Northwest Normal Univ, Coll Chem & Chem Engn, Lanzhou 730070, Gansu, Peoples R China in 2021, Cited 91. Recommanded Product: 123-11-5. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

The first synthesis of highly strained spirocyclobutane-pyrrolines via a palladium-catalyzed tandem Narasaka-Heck/C(sp(3) or sp(2))-H activation reaction is reported here. The key step in this transformation is the activation of a delta-C-H bond via an in situ generated sigma-alkyl-Pd(II) species to form a five-membered spiro-palladacycle intermediate. The concerted metalation-deprotonation (CMD) process, rate-determining step, and energy barrier of the entire reaction were explored by density functional theory (DFT) calculations. Moreover, a series of control experiments was conducted to probe the rate-determining step and reversibility of the C(sp(3))-H activation step.

About 4-Methoxybenzaldehyde, If you have any questions, you can contact Wei, WX; Li, YK; Wen, YT; Li, M; Li, XS; Wang, CT; Liu, HC; Xia, Y; Zhang, BS; Jiao, RQ; Liang, YM or concate me.. Recommanded Product: 123-11-5

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Aerobic photooxidative hydroxylation of boronic acids catalyzed by anthraquinone-containing polymeric photosensitizer WOS:000519586300057 published article about TRANSITION-METAL-FREE; ARYLBORONIC ACIDS; VISIBLE-LIGHT; OXIDATIVE HYDROXYLATION; IPSO-HYDROXYLATION; PHOTOREDOX CATALYSIS; ORGANIC FRAMEWORK; ARYL; EFFICIENT; PHENOLS in [Chen, Yang; Hu, Jianhua] Fudan Univ, Dept Macromol Sci, State Key Lab Mol Engn Polymers, 2005 Songhu Rd, Shanghai 200438, Peoples R China; [Ding, Aishun] Fudan Univ, Dept Chem, 2005 Songhu Rd, Shanghai 200438, Peoples R China in 2020, Cited 48. Recommanded Product: 3-(Trifluoromethyl)phenol. The Name is 3-(Trifluoromethyl)phenol. Through research, I have a further understanding and discovery of 98-17-9

We report herein the synthesis of a polymeric photosensitizer and its application in aerobic photooxidative hydroxylation of boronic acids. The polymeric photosensitizer was synthesized by the condensation of anthraquinone-2-carbonyl chloride (AQ-2-COCl) with poly (2-hydroxyethyl methacrylate) (PHEMA). The photo-oxidative hydroxylation of boronic acids using anthraquinone-containing-poly (2-hydroxyethyl methacrylate) (AQ-PHEMA) was then explored and shown to exhibit high efficiency and broad scope. Moreover, AQ-PHEMA could be easily recovered and reused for more than 20 times without significant loss of the catalytic activity.

Recommanded Product: 3-(Trifluoromethyl)phenol. About 3-(Trifluoromethyl)phenol, If you have any questions, you can contact Chen, Y; Hu, JH; Ding, AS or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles