On October 15, 2018, Uredi, Dilipkumar; Motati, Damoder Reddy; Watkins, E. Blake published an article.Recommanded Product: 1,5-Dimethyl-1H-indole-2-carbaldehyde The title of the article was A Unified Strategy for the Synthesis of β-Carbolines, γ-Carbolines, and Other Fused Azaheteroaromatics under Mild, Metal-Free Conditions. And the article contained the following:
An efficient, unified approach for the synthesis of β-carbolines, γ-carbolines, and other fused azaheteroaroms. has been realized under metal-free conditions, from propargylic amines and (hetero)aromatic aldehydes. This unified strategy provides β- and γ-carbolines as well as a range of fused azaheteroaroms. with a broad substrate scope and excellent functional group compatibility. The formal synthesis of oxopropalines D and G has been achieved on gram scale using I, in a one-pot reaction from com. available materials (previous shortest reported route to I was 5 steps). NMR studies of the conversion of imine intermediate II to β-carboline I were conducted and revealed that the reaction proceeded through an allene intermediate. The experimental process involved the reaction of 1,5-Dimethyl-1H-indole-2-carbaldehyde(cas: 883526-76-9).Recommanded Product: 1,5-Dimethyl-1H-indole-2-carbaldehyde
The Article related to propargylic amine heteroaromatic aldehyde isomerization azacyclization proton shift, carboline preparation metal free, fused azaheteroarom preparation, oxopropalines d formal synthesis, formal synthesis oxopropalines g and other aspects.Recommanded Product: 1,5-Dimethyl-1H-indole-2-carbaldehyde
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles