On July 31, 1997, Nilsson, Kurt G.I.; Pan, Hefeng; Larsson-Lorek, Ulla published an article.Recommanded Product: 130539-43-4 The title of the article was Synthesis of modified carbohydrates with glycosidases: stereo- and regiospecific syntheses of lactosamine derivatives and related compounds. And the article contained the following:
Different lactosamine derivatives, modified in the 2-N- and anomeric positions and suitable as intermediates for synthesis of Lewis-x and related compounds, were prepared with high specificity on a multigram scale directly from lactose, employing different D-glucosamine derivatives as acceptors and the abundant β-D-galactosidase from Bullera singularis as catalyst. Thus, Me O-β-D-galactopyranosyl-(1→4)-2-azido-2-deoxy-β-D-glucopyranoside, Et O-β-D-galactopyranosyl-(1→4)-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside and Et O-β-D-galactopyranosyl-(1→4)-2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-1-thio-β-D-glucopyranoside were formed in 20-40% yield as calculated based on added acceptor. The 2-phthalimido derivative was isolated in crystalline form without chromatog. (extraction/crystallization procedure). The trisaccharide derivative Et O-β-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside was also isolated. The corresponding cellobiosamine derivatives were similarly obtained from cellobiose using the same type of catalyst and acceptors. The β-D-galactosidase from bovine testes was found to catalyze the highly specific formation of the β(1→6)-linked derivative Et O-β-galactopyranosyl-(1→6)-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside from lactose and Et 2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside. Et O-α-L-fucopyranosyl-(1→4)-2-amino-6-O-benzyl-2-deoxy-1-thio-β-D-glucopyranoside, suitable as an intermediate for preparation of Lewis-a and related compounds, was obtained from p-nitrophenyl α-L-fucopyranoside and 2-amino-6-O-benzyl-2-deoxy-1-thio-β-D-glucopyranoside, employing α-L-fucosidase from bovine testes as catalyst. The experimental process involved the reaction of Ethyl 2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-thio-beta-D-glucopyranoside(cas: 130539-43-4).Recommanded Product: 130539-43-4
The Article related to galactopyranosylazidodeoxyglucopyranoside fucopyranosylaminodeoxythioglucopyranoside preparation glycosidase, lactose transglycosidation galactosidase, oligosaccharide stereochem preparation glycosidase and other aspects.Recommanded Product: 130539-43-4
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles