Zhang, Wen-Qian’s team published research in Organic Letters in 2022-09-16 | CAS: 57663-18-0

Organic Letters published new progress about Benzoyl chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 57663-18-0 belongs to class indole-building-block, name is Methyl 2-methyl-1H-indole-5-carboxylate, and the molecular formula is C11H11NO2, Product Details of C11H11NO2.

Zhang, Wen-Qian published the artcileDearomative Arylcyanation of Indoles via C-CN Bond Activation Enabled by Ni/Lewis Acid Cooperative Catalysis, Product Details of C11H11NO2, the main research area is isoindoloindole carbonitrile preparation stereoselective nickel Lewis acid cooperative catalysis; indolecarbonyl benzonitrile intramol dearomative arylcyanation.

A nickel/Lewis acid cooperatively catalyzed intramol. dearomative arylcyanation of indoles is presented. The reaction proceeds through a C-CN bond activation, dearomatization, and benzylic cyanation sequence, affording 3-cyano fused indolinyl heterocycles in good to excellent yields and excellent diastereoselectivity. The asym. version of the reaction can be established in moderate enantioselectivity by using a chiral ligand.

Organic Letters published new progress about Benzoyl chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 57663-18-0 belongs to class indole-building-block, name is Methyl 2-methyl-1H-indole-5-carboxylate, and the molecular formula is C11H11NO2, Product Details of C11H11NO2.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles