Synthesis, characterization and evaluation of antioxidant activity of N-([1,3,4]oxadiazino[6,5-b] substituted indol-3-ylmethyl)aniline was written by Padma, Bairy;Gadea, Sammaiah. And the article was included in Pharma Innovation in 2020.Computed Properties of C8H4N2O4 This article mentions the following:
A novel series of N-([1,3,4]oxadiazino[6,5-b] substituted indol-3-ylmethyl)anilines I [R = H, 5-Me, 7-Br, etc.] were synthesized in good yields and characterized by IR, NMR and mass spectral analyses. Synthesized compounds I were evaluated for their antioxidant activity by standard DPPH assay method. By taking ascorbic acid as standard drug, among the series the compounds I [R = 7-Cl, 5-COOEt, 7-OH] were potent antioxidant and remaining compounds showed significant antioxidant activity. In the experiment, the researchers used many compounds, for example, 7-Nitroindoline-2,3-dione (cas: 112656-95-8Computed Properties of C8H4N2O4).
7-Nitroindoline-2,3-dione (cas: 112656-95-8) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Computed Properties of C8H4N2O4
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles