Selective reduction of carbonyl groups in the presence of low-valent titanium reagents was written by Lin, Wei;Hu, Ming-Hua;Feng, Xian;Fu, Lei;Cao, Cheng-Pao;Huang, Zhi-Bin;Shi, Da-Qing. And the article was included in Tetrahedron Letters in 2014.Reference of 774-47-0 This article mentions the following:
The chemoselective reduction of several structurally diverse compounds containing carbonyl groups was achieved in the presence of low-valent Ti reagents. This novel synthetic method provides easy access to highly selective reduction of carbonyl groups, and possesses several advantages including one-step procedure, convenient manipulation, good to excellent yields, and short reaction times. In the experiment, the researchers used many compounds, for example, 5,6-Difluoroindoline-2,3-dione (cas: 774-47-0Reference of 774-47-0).
5,6-Difluoroindoline-2,3-dione (cas: 774-47-0) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Reference of 774-47-0
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles