AlCl3-mediated aromatic phenylthiation with N-phenylthiophthalimide was written by Suwa, Satoshi;Sakamoto, Takeshi;Kikugawa, Yasuo. And the article was included in Chemical & Pharmaceutical Bulletin in 1999.Electric Literature of C14H9NO2S This article mentions the following:
N-Phenylthiophthalimide reacts with AlCl3 or TiCl4 in arenes to give phenylthiated arenes alone via a phenylsulfenium ion intermediate. MNDO MO calculations revealed that the pos. charge preferentially populates the sulfur atom rather than the Ph group in the phenylsulfenium ion. In the experiment, the researchers used many compounds, for example, 2-(Phenylthio)isoindoline-1,3-dione (cas: 14204-27-4Electric Literature of C14H9NO2S).
2-(Phenylthio)isoindoline-1,3-dione (cas: 14204-27-4) belongs to indole derivatives. The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Electric Literature of C14H9NO2S
Referemce:
Indole alkaloid derivatives as building blocks of natural products from闂佽壈浜崹淇沜illus thuringiensis闂佽壈浜粋鍧闂佽壈浜崹淇沜illus velezensis闂佽壈浜粋鍧 their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles