Isoindoles from phthalimidines. N-Arylisoindoles was written by Kovtunenko, V. A.;Kucherenko, T. T.;Kornilov, M. Yu.;Tyltin, A. K.;Turov, A. V.;Babichev, F. S.. And the article was included in Khimiya Geterotsiklicheskikh Soedinenii in 1987.Electric Literature of C14H11NO This article mentions the following:
N-Arylisoindoles I (R = Ph, 4-MeC6H4, 4-BrC6H4) were prepared by reduction of the resp. phthalimidines II (same R) with Li[(MeOCH2CH2O)2AlH2]. In the experiment, the researchers used many compounds, for example, 2-Phenylisoindolin-1-one (cas: 5388-42-1Electric Literature of C14H11NO).
2-Phenylisoindolin-1-one (cas: 5388-42-1) belongs to indole derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Electric Literature of C14H11NO
Referemce:
Indole alkaloid derivatives as building blocks of natural products from闂佽壈浜崹淇沜illus thuringiensis闂佽壈浜粋鍧闂佽壈浜崹淇沜illus velezensis闂佽壈浜粋鍧 their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles