Microwave-Assisted Reductive Amination of 2-Carboxybenzaldehydes with Amines for the Synthesis of N-Substituted Isoindolin-1-ones was written by Muvvala, Subhashini;Kumari, Krishnaiah;Miriyala, Venkatesh;Mogili, Padma;Chidara, Sridhar;Maddirala, Shambabu Joseph;Saxena, Abhishek;Behera, Manoranjan. And the article was included in ChemistrySelect in 2022.Name: 2-Phenylisoindolin-1-one This article mentions the following:
Microwave-assisted, transition metal free methodol. for the synthesis of N-substituted isoindolin-1-ones I [R1 = H, F; R2 = i-Pr, Ph, PhCH2, 2-(piperidin-1-yl)ethyl, etc.] from 2-carboxybenzaldehydes II and various amines R2NH2 by reductive amination reaction using formic acid has been described. This method is relatively simple, benign, safe and tolerates a variety of functional groups. In the experiment, the researchers used many compounds, for example, 2-Phenylisoindolin-1-one (cas: 5388-42-1Name: 2-Phenylisoindolin-1-one).
2-Phenylisoindolin-1-one (cas: 5388-42-1) belongs to indole derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Name: 2-Phenylisoindolin-1-one
Referemce:
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Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles