Synthetic Route of 776-41-0, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.776-41-0, Name is Ethyl 1H-indole-3-carboxylate, molecular formula is C11H11NO2. In a article£¬once mentioned of 776-41-0
A method for catalytic synthesis of indole compounds (by machine translation)
The invention discloses a process for catalytic synthesis of indole compounds, comprising the following steps : (1) the adjoining nitrostyrolene or its derivatives, frequency that alcohol esterjoint boric acid, alkali and lower saturated monohydric alcohol reaction stirring under a nitrogen atmosphere ; (2) the step (1) cooling to room temperature, the reaction product of, adding ethyl acetate to be fully mixed, filtered, washed with ethyl acetate ; (3) steps turns on lathe does (2) the organic phase of the material of the lower saturated monohydric alcohol, a silica gel column, then by the petroleum ether and ethyl acetate for the elution agent leaching the above-mentioned silica gel column, the product to be purified, i.e. the indole compound. Process for catalytic synthesis of this invention under the neutral condition, by utilizing cheap joint boric acidfrequency that ester as the raw material, by friendly lower saturated monohydric alcohol used as a solvent, by a simple operation to obtain the indole compound, cheap raw material cost, high efficiency, good safety, has a wide range of expansibility, and good industrial application prospects. (by machine translation)
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 776-41-0, and how the biochemistry of the body works.Synthetic Route of 776-41-0
Reference£º
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles