Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 100-51-6, Name is Benzyl Alcohol, molecular formula is , belongs to indole-building-block compound. In a document, author is Thien Phuc Le, COA of Formula: C7H8O.
Revisiting the Cu-ll-Catalyzed Asymmetric Friedel-Crafts Reaction of Indole with Trifluoropyruvate
A Cu-II complex of bisamidine ligand L-s catalyzes the Friedel-Crafts (FC) reaction of indole with trifluoropyruvate with high generality, yielding the highly enantiomerically enriched FC adduct. Electron-rich indoles have high reactivity due to a dual activation mechanism showing second-order kinetics for Cu-II, whereas indoles with a soft substituent at C(4) proceed at a rate that is three orders of magnitude lower via a coordination mechanism, which reverses the sense of enantioselectivity.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 100-51-6, in my other articles. COA of Formula: C7H8O.
Reference:
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles