The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 50-35-1, Name is Thalidomide, SMILES is O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3)=O, in an article , author is Petko, Kirill I., once mentioned of 50-35-1, Recommanded Product: Thalidomide.
New N-difluoromethylindoles: features of N-difluoromethylation of indoles with electron-donor or electron-withdrawing substituents
The study of the difluoromethylation of various indole derivatives containing both electron-donating and electron-withdrawing groups was carried out. N-Difluoromethyl derivatives of indole with methoxy, methyl, nitro, cyano, amino groups and bromine atom were isolated and fully characterized.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles