The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 148-53-8, Name is 3-Methoxysalicylaldehyde, SMILES is OC1=C(OC)C=CC=C1C=O, in an article , author is Jafarpour, Farnaz, once mentioned of 148-53-8, Product Details of 148-53-8.
A Fast Track to Ind les and Annulated Indoles through ortho- vs ipso-Amination of Aryl Halides
A complementary site selective ortho- vs ipsoamination of aryl halides using non-electrophilic amine sources for construction of indole scaffolds is reported. A palladium-catalyzed alkyne insertion/C H activation/palladacycle amination via merger of three easily diversified components including iodoarenes, alkynes, and amines delivers indoles with different substitution patterns even in gram scales. By employing ortho-bromoanilines, a consecutive annulative pi-extension of indoles proceeds to construct indolo[1,2-f]phenanthridine scaffolds via four C-C and C-N bond formations in one pot.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles