COA of Formula: C7H8O. In 2019.0 BIOORGAN MED CHEM published article about BRIDGED NUCLEIC-ACID; ANTISENSE OLIGONUCLEOTIDES; ANALOGS; LNA in [Fujisaka, Aki; Hari, Yoshiyuki; Takuma, Hiroko; Rahman, S. M. Abdur; Yoshikawa, Haruhisa; Pang, Juanjuan; Imanishi, Takeshi; Obika, Satoshi] Osaka Univ, Grad Sch Pharmaceut Sci, 1-6 Yamadaoka, Suita, Osaka 5650871, Japan; [Fujisaka, Aki] Osaka Ohtani Univ, Fac Pharm, Nishikiori Kita 3-11-1, Tondabayashi, Osaka 5848540, Japan; [Hari, Yoshiyuki] Tokushima Bunri Univ, Fac Pharmaceut Sci, Yamashiro, Tokushima 7708514, Japan; [Rahman, S. M. Abdur] Univ Dhaka, Fac Pharm, Dept Clin Pharm & Pharmacol, Dhaka 1000, Bangladesh; [Yoshikawa, Haruhisa; Imanishi, Takeshi] BNA Inc, 7-7-20 Saito Asagi, Osaka 5670085, Japan in 2019.0, Cited 34.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.
We efficiently synthesized 2′-O,4′-C-aminomethylene-bridged nucleic acid (2′,4′-BNA(NC)) monomers bearing the four nucleobases, guanine, adenine, thymine, and 5-methylcytosine and incorporated these monomers into oligonucleotides. Initially, we carried out the transglycosylation reaction on several 2′-O-substituted 5-methyluridines to evaluate the effects of 2′-substitutions on this reaction. Under the optimized conditions, purine nucleobases were successfully introduced, and 2′,4′-BNA(NC) monomers bearing adenine or guanine were obtained over several steps. In addition, the improved synthesis of the 2′,4′-BNA(NC) monomers bearing thymine or 5-methylcytosine was also achieved. The obtained 2′,4′-BNA(NC) monomers were subsequently incorporated into oligonucleotides and the duplex-forming abilities of the modified oligonucleotides were investigated. Duplexes containing 2′,4′-BNA(NC) monomers in both or either strands were found to possess excellent thermal stabilities.
About Benzyl Alcohol, If you have any questions, you can contact Fujisaka, A; Hari, Y; Takuma, H; Rahman, SMA; Yoshikawa, H; Pang, J; Imanishi, T; Obika, S or concate me.. COA of Formula: C7H8O
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles