COA of Formula: C8H8O2. In 2021 BIOORG MED CHEM LETT published article about CATALYZED N-ALKYLATION; BIOLOGICAL-ACTIVITIES; ANTIOXIDANT ACTIVITY; DERIVATIVES; ANTICONVULSANT; FILMS; ALCOHOLS; DESIGN; AMINES in [Kumar, C. B. Pradeep] Malnad Coll Engn, Dept Chem, Hassan 573202, India; [Raghu, M. S.; Parashuram, L.] New Horizon Coll Engn, Dept Chem, Bengaluru 560103, India; [Prathibha, B. S.; Prashanth, M. K.] BNM Inst Technol, Dept Chem, Bengaluru 560070, India; [Kanthimathi, G.] Ramco Inst Technol, Dept Chem, Rajapalayam 626117, Tamil Nadu, India; [Kumar, K. Yogesh] Jain Univ, Sch Engn & Technol, Dept Chem, Ramanagara 562112, India; [Alharthi, Fahad A.] King Saud Univ, Coll Sci, Dept Chem, Riyadh 11451, Saudi Arabia in 2021, Cited 50. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.
A Ta2O5-anchored-piperidine-4-carboxylic acid (PPCA) nanoparticle has been synthesized and characterized. It was then used as a highly effective nanocatalyst for the synthesis of quinolin-2(1H)-one derivatives through C-O bond functionalization. The special advantage of this heterogeneous solid catalyst is the reusability of the catalyst for up to five cycles without any noticeable reduction in product yields. In comparison, healthy reaction profiles, wide substrate scope, excellent yields and easy workup conditions are the notable highlights of this approach. All the compounds were tested for their anticancer activity against MCF-7 (human breast), HepG2 (human liver), HCT116 (human colorectal), and PC-3 (human prostate) cancer cell lines with the MTT assay. All the compounds were shown to have moderate to good inhibitory effects on tested cancer cell lines. Besides, compounds 5b, 5c and 5d showed good selectivity against epidermal growth factor receptor-tyrosine kinase (EGFR-TK). Molecular docking results showed that active compounds showed a good affinity towards EGFR kinase (PDB ID: 6V6O) by forming two hydrogen bonds with Cys-797 and Tyr-801. All the compounds were screened for computational ADMET and Lipinski analysis.
COA of Formula: C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Kumar, CBP; Raghu, MS; Prathibha, BS; Prashanth, MK; Kanthimathi, G; Kumar, KY; Parashuram, L; Alharthi, FA or concate me.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles