Recently I am researching about STAPHYLOCOCCUS-AUREUS MRSA; METHICILLIN-RESISTANT; ANALOGS, Saw an article supported by the . Published in SPRINGER in DORDRECHT ,Authors: Narwal, S; Kumar, S; Verma, PK. The CAS is 99-93-4. Through research, I have a further understanding and discovery of 4′-Hydroxyacetophenone. Product Details of 99-93-4
Chalcones are open-chain flavonoids which contains two aromatic rings are joined by 3-carbons alpha-, beta-unsaturated carbonyl chain. The, beta-unsaturated ketonic group which is liable for the antimicrobial activity of the chalcone is additionally of vast use in further chemical modification into a variety of heterocyclic compounds. A new series of chalcone derivatives was synthesized and characterized by spectral analysis (IR, 1H-NMR, 13C-NMR, MS and elemental analysis) and evaluated for its in vitro antimicrobial activity against bacterial (Gram negative and Gram positive) and fungal strains using tube dilution method. The antimicrobial screening results revealed that some compounds of the series 1 (MICpa = 1.16 mu M), 3 (MICbs = 1.82 mu M), 6 (MICan = 2.09 mu M), 8 (MICec and se = 0.94 and 1.88 mu M) and 17 (MICsa and ca = 0.91 and 1.81 mu M) showed the most promising antimicrobial activity against both Gram-positive as well as Gram-negative bacterial and fungal strains, and comparable to the standard drugs used as positive control (cefadroxil and fluconazole).
Product Details of 99-93-4. About 4′-Hydroxyacetophenone, If you have any questions, you can contact Narwal, S; Kumar, S; Verma, PK or concate me.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles