An article Oxidative Cross-Coupling of Alcohols and Amines Catalyzed by TEMPO under Transition-Metal-Free Condition WOS:000542426900008 published article about ONE-POT SYNTHESIS; AEROBIC OXIDATION; SECONDARY-AMINES; 2-SUBSTITUTED QUINAZOLINES; MICHAEL-ADDITION; N-ALKYLATION; IMINES; EFFICIENT; RUTHENIUM; ALDEHYDES in [Chandrasekaran, Revathi; Carlose, Elgin; Muthu, Ajun E.; Suresh, Athira; Chinnusamy, Tamilselvi] Indian Inst Sci Educ & Res Thiruvananthapuram, Sch Chem, Thiruvananthapuram 695551, Kerala, India in 2020.0, Cited 76.0. Name: Benzyl Alcohol. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6
The transition-metal-free catalytic system TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl)/NaOCl promotes an efficient oxidative cross-coupling of alcohols and amines to imines4as well as 1,2,3,4-tetrahydroquniazolines6. A wide variety of alcohols and amines were well tolerated in the catalytic condition. This protocol was operationally very simple, efficiently scaled up to 100 mmol with as low as 0.5 mol% of catalyst loading and applied to the synthesis of biologically important diuretic drug molecule thiabutazide9in 98% yield. The recyclable TEMPO catalyst was showed similar reactivity. Moreover, it was reused upto five runs without much drop in the activity. The green chemistry metrics of the estabilished method (E-factor value 17.80, Atom economy 90.7%, Carbon efficiency 98% and Overall efficiency 97.95%) proved to be efficient to the existing methods.
About Benzyl Alcohol, If you have any questions, you can contact Chandrasekaran, R; Carlose, E; Muthu, AE; Suresh, A; Chinnusamy, T or concate me.. Name: Benzyl Alcohol
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles