Recently I am researching about ENANTIOSELECTIVE SYNTHESIS; ASYMMETRIC HECK; OXINDOLES; ARYLATION; POTENT, Saw an article supported by the ARIADME, part of the European FP7 ITN Community’s Seventh Framework Programme [607517]. Product Details of 100-51-6. Published in GEORG THIEME VERLAG KG in STUTTGART ,Authors: Adeyemi, A; Wetzel, A; Bergman, J; Branalt, J; Larhed, M. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol
A method for highly regio- and stereoselective intramolecular Mizoroki-Heck 5- exo cyclization of aryl iodides to the corresponding spirooxindoles has been developed. Electron-rich and electron-deficient aryl iodide precursors were selectively ring-closed with high stereoselectivity and good yields. The double-bond position in the cyclopentene ring was controlled by careful choice of reaction conditions. These rare spiro compounds were further functionalized to rigidified unnatural amino acid derivatives by a subsequent gas-free Pd(0)-catalyzed alkoxycarbonylation, followed by selective O – and N -deprotections.
About Benzyl Alcohol, If you have any questions, you can contact Adeyemi, A; Wetzel, A; Bergman, J; Branalt, J; Larhed, M or concate me.. Safety of Benzyl Alcohol
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles