Product Details of 150-76-5. Recently I am researching about HYDROXAMIC ACID; EUGENOL; DERIVATIVES; ANTIOXIDANT; 5-LIPOXYGENASE; REARRANGEMENT; LIPOXYGENASE; DESIGN; PHENOL; SAR, Saw an article supported by the Research Council of Mashhad University of Medical Science [980124]. Published in WILEY in HOBOKEN ,Authors: Alavi, SJ; Seyedi, SM; Saberi, S; Safdari, H; Eshghi, H; Sadeghian, H. The CAS is 150-76-5. Through research, I have a further understanding and discovery of Mequinol
In this study, a series of mono- and diallylphenol derivative were designed, synthesized, and evaluated as potential human 15-lipoxygenase-1 (15-hLOX-1) inhibitors. Radical scavenging potency of the synthetic allylphenol derivatives was assessed and the results were in accordance with lipoxygenase (LOX) inhibition potency. It was found that the electronic natures of allyl moiety andparasubstituents play the main role in radical scavenging activity and subsequently LOX inhibition potency of the synthetic inhibitors. Among the synthetic compounds, 2,6-diallyl-4-(hexyloxy)phenol (42) and 2,6-diallyl-4-aminophenol (47) showed the best results for LOX inhibition (IC50= 0.88 and 0.80 mu M, respectively).
About Mequinol, If you have any questions, you can contact Alavi, SJ; Seyedi, SM; Saberi, S; Safdari, H; Eshghi, H; Sadeghian, H or concate me.. Product Details of 150-76-5
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles