An article Design, synthesis and antimicrobial activity of novel 2-aminothiophene containing cyclic and heterocyclic moieties WOS:000660488600004 published article about THIOPHENE; DERIVATIVES; FACILE in [Asiri, Yahya, I] King Khalid Univ, Coll Pharm, Dept Pharmacol, POB 960, Abha 61421, Saudi Arabia; [Bin Muhsinah, Abdullatif; Alsayari, Abdulrhman] King Khalid Univ, Coll Pharm, Dept Pharmacognosy, Abha, Saudi Arabia; [Venkatesan, Kumar; Mabkhot, Yahia N.] King Khalid Univ, Coll Pharm, Dept Pharmaceut Chem, Abha 61441, Saudi Arabia; [Al-Ghorbani, Mohammed] Taibah Univ, Coll Sci & Arts, Dept Chem, Madina Monora, Saudi Arabia; [Al-Ghorbani, Mohammed] Thamar Univ, Coll Educ, Dept Chem, Thamar, Yemen in 2021, Cited 19. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5. Safety of 4-Methoxybenzaldehyde
One of the major challenges in the community and healthcare was an impedance of pathogenic bacteria to antibiotics. This work developed 2-aminothiophene derivatives as novel antimicrobial agents. Various 2-aminothiophene derivatives (3a-f, 5a-c, 6a, b, 7, 8a, b and 9) with cyclic and heterocyclic moieties at 5-position were synthesized, and characterized using NMR, IR, and mass spectroscopic techniques. The newly synthesized compounds were evaluated for their antimicrobial activity against bacteria S. pneumoniae, B. subtilis, P. aeruginosa, E. coli, and fungi A. fumigatus, S. mracemosum, G. candidum, C. albicans. Compound 3a with OH group at para position of phenyl ring exhibited significant antibacterial activity stronger than that of the drug standards Ampicillin and Gentamicin. Compound 6b possess pyrazole ring and compound 9 bearing pyridine ring showed promising antifungal activity compare to the standard drug Amphotericin B. The remaining compounds exhibited good to moderate inhibitory activities. In summary, the results suggest that the compounds from 2-aminothiophene derivatives can be used as antimicrobial agents.
Safety of 4-Methoxybenzaldehyde. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Asiri, YI; Bin Muhsinah, A; Alsayari, A; Venkatesan, K; Al-Ghorbani, M; Mabkhot, YN or concate me.
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles