An article Gold-Catalyzed Skeletal Rearrangement of Alkenes: Regioselective Synthesis of Skeletally Diverse Tricyclic Heterocycles and Mechanistic Investigations WOS:000664333800023 published article about BOND-CLEAVAGE; CYCLOADDITION; CONSTRUCTION in [Qin, Xiao-Yan; Meng, Fan-Tao; Tu, Shu-Jiang; Hao, Wen-Juan; Jiang, Bo] Jiangsu Normal Univ, Sch Chem & Mat Sci, Jiangsu Key Lab Green Synthet Chem Funct Mat, Xuzhou 221116, Jiangsu, Peoples R China; [Wang, Mian; Wang, Jianyi] Guangxi Univ, Med Coll, Nanning 530004, Peoples R China in 2021, Cited 90. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5. Recommanded Product: 123-11-5
Transition metal-catalyzed skeletal rearrangement reactions have rapid advances in organic community. Their development benefits synthetic methodologies by providing versatile and flexible approaches toward special molecular scaffolds with high selectivity. Herein, a gold-catalyzed skeletal rearrangement of alkenes with alkynyl bromides is reported, enabling direct and regioselective generation of more than 50 examples of skeletally diverse tricyclic heterocycles, namely, syn-tetrahydrocyclopenta[b]indoles and benzofuro[3,2-b]pyridines, with generally good yields. This protocol could tolerate terminal unactivated and internal activated alkenes under air conditions, which is hitherto unreported in gold catalysis and scarcely realized by other metal-catalyzed reactions, thus opening avenues for the regioselective assembly of heterocyclic systems with high efficiency. Aside from examining the scope of this skeletal rearrangement, mechanistic investigations to explain the regioselectivity of forming syn-tetrahydrocyclopenta[b]indoles and benzofuro[3,2-b]pyridines were conducted by systematic theoretical calculations.
Recommanded Product: 123-11-5. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles