Category: indole-building-block. Authors Fan, J; Mah, JQ; Yang, MC; Su, MD; So, CW in AMER CHEMICAL SOC published article about in [Fan, Jun; Mah, Jian-Qiang; So, Cheuk-Wai] Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, Singapore 637371, Singapore; [Yang, Ming-Chung; Su, Ming-Der] Natl Chiayi Univ, Dept Appl Chem, Chiayi 60004, Taiwan; [Su, Ming-Der] Kaohsiung Med Univ, Dept Med & Appl Chem, Kaohsiung 80708, Taiwan in 2021.0, Cited 42.0. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5
The use of the N-phosphinoamidinato NHC-diborene catalyst 2 for hydroboration is described. The N-phosphinoamidine tBu(2)PN(H)C(Ph)=N(2,6-iPr(2)C(6)H(3)) was reacted with nBuLi in Et2O to afford the lithium derivative, which was then treated with B2Br4(SMe2)(2) in toluene to form the N-phosphinoamidinate-bridged diborane 1. It was reacted with the N-heterocyclic carbene IMe (:C{N(CH3)C(CH3)}(2)) and excess potassium graphite at room temperature in toluene to give the N-phosphinoamidinato NHC-diborene compound 2. It can stoichiometrically activate ammonia-borane and carbon dioxide. It also showed catalytic capability. A 2 mol % portion of 2 catalyzed the hydroboration of carbon dioxide (CO2) with pinacolborane (HBpin) in deuterated benzene (C6D6) at 110 degrees C (conversion >99%), which afforded the methoxyborane [pinBOMe] (yield 97.8%, TOF 33.3 h(-1)) and the bis(boryl) oxide [(pinB)(2)O]. In addition, 5 mol % of 2 catalyzed the N-formylation of secondary and primary amines by carbon dioxide and pinacolborane to yield the N-formamides (average yield 91.6%, TOF 25.9 h(-1)). Moreover, 2 showed chemoselectivity toward catalytic hydroboration of carbonyl compounds. In mechanistic studies, the B=B double bond in compound 2 activated the substrates, the intermediates of which then underwent hydroboration with pinacolborane to yield the products and regenerate catalyst 2.
Category: indole-building-block. Welcome to talk about 123-11-5, If you have any questions, you can contact Fan, J; Mah, JQ; Yang, MC; Su, MD; So, CW or send Email.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles