An article Deep Eutectic Solvent Mediated One-Pot Synthesis of Hydrazinyl-4-Phenyl-1,3-Thiazoles WOS:000477274800001 published article about ANTIMICROBIAL ACTIVITY; 2,4-DISUBSTITUTED THIAZOLES; 3-COMPONENT SYNTHESIS; DERIVATIVES; ANTIBACTERIAL; WATER in [Kaldareh, Mahdiye Foroughi; Mokhtary, Masoud; Nikpassand, Mohammad] Islamic Azad Univ, Rasht Branch, Dept Chem, Rasht, Iran in 2021, Cited 27. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4. Recommanded Product: 99-93-4
One-pot synthesis of hydrazinyl-4-phenyl-1,3-thiazole derivatives was developed by three-component reaction of various ketones or aldehydes, phenacyl chloride, and thiosemicarbazid in the presence of choline chloride/urea as a deep eutectic solvent (DES) at 70 degrees C. The products formed in excellent yields over short reaction times under an environmentally friendly condition. This method develops by using an environmentally benign synthetic method along with the use of a cost-effective catalyst. The study of antibacterial activity revealed that the compounds (4j, 4k, 4l, 4m, 4s, and 4t) showed good inhibition toward Escherichia coli.
About 4′-Hydroxyacetophenone, If you have any questions, you can contact Kaldareh, MF; Mokhtary, M; Nikpassand, M or concate me.. Recommanded Product: 99-93-4
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles