An article Nanoporous AlSBA-15 catalysed Claisen-Schmidt condensation for the synthesis of novel and biologically active chalcones WOS:000540213400017 published article about HUMAN SERUM-ALBUMIN; MICROWAVE IRRADIATION; DERIVATIVES; ANTIOXIDANT; CURCUMIN; ANTICANCER; DESIGN in [Chandrasekar, Govindasamy] Imam Abdhulrahman Bin Faisal Univ, Coll Sci, Basic & Appl Sci Res Ctr, POB 31441, Dammam, Saudi Arabia; [Elamathi, Palani; Balamurali, M. M.] Vellore Inst Technol, Sch Adv Sci, Chem Div, Chennai, Tamil Nadu, India in 2020.0, Cited 35.0. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4. Recommanded Product: 4′-Hydroxyacetophenone
Mesoporous AlSBA-15 catalysts (n(Si)/n(Al)ratios of 41, 129 and 210) were synthesized by sol-gel method. These materials were characterized by XRD, N(2)sorption, FTIR, TPD-NH3, FESEM, EDX, and TEM analysis. XRD analysis of AlSBA-15 catalysts confirmed the existence of well-ordered crystalline structure havingp6mmsymmetry. N(2)sorption isotherm of AlSBA-15 catalysts showed a type IV adsorption isotherm with H1 hysteresis loops. SEM analysis of AlSBA-15 (41) indicated worm-like particle morphology with a size range of 3 mu m with co-occurrence of smaller particles of size ca. 1 mu m. TEM analysis of AlSBA-15 (41) showed existence of uniform array of tubular nano-channels. The catalytic application of AlSBA-15 catalysts was tested on industrially important chalcones synthesis via Claisen-Schmidt condensation reaction in environment friendly approach. The reaction parameters such as time, temperature,n(Si)/n(Al)ratio, catalyst amount, and catalyst stability were investigated. AlSBA-15 (41) catalyst showed an excellent catalytic performance with 98% 1-tetralone conversion with 100% selectivity of compound 1c (91% yield) within 120 min AlSBA-15 (129) and AlSBA-15 (210) catalysts. The anti-oxidant activity of the synthesised chalcones were investigated by various in-vitro procedures, including radical scavenging potentials-1, 1-diphenyl-2-picryl-hydrazil, hydrogen peroxide scavenging, and ferric reducing potential assay. The new chalcone derivatives synthesised in this work showed a very good antioxidant activity and some were found to be more active than the parent chalcones, (E)-3-(4-hydroxy-3-methoxyphenyl)-1-phenylprop-2-en-1-one (compound 8c), and standard antioxidant (curcumin).
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles