Authors Simm, PE; Sekar, P; Richardson, J; Davies, PW in AMER CHEMICAL SOC published article about FORMAL 3+2 CYCLOADDITION; RAPID ACCESS; YNAMIDES; DERIVATIVES in [Simm, Peter E.; Sekar, Prakash; Davies, Paul W.] Univ Birmingham, Sch Chem, Birmingham B15 2TT, W Midlands, England; [Richardson, Jeffery] Lilly UK, Windlesham GU20 6PH, Surrey, England in 2021.0, Cited 56.0. HPLC of Formula: C8H8O2. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5
The combination of nucleophilic nitrenoids and pacid catalysis has emerged as a powerful tool in heterocycle synthesis. Accessing more varied heterocycle-substitution patterns by maintaining the same reaction pathways across different alkynes remains a challenge. Here we show that Au(I) catalysis of isoxazole-based nitrenoids with alkynyl thioethers provides controlled access to (3 + 2) annulation by a regioselective addition beta to the sulfenyl group. The reaction with isoxazole-containing nitrenoids delivers sulfenylated pyrroles and indoles as single regioisomers bearing useful functional groups and structural variety.
HPLC of Formula: C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Simm, PE; Sekar, P; Richardson, J; Davies, PW or concate me.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles