Synthesis and reactions of N-aroyloxycyclohex-4-ene-1,2-dicarboximides was written by Aly, N. F.;Fahmy, A. F. M.;Aly, N. Y.;Essawy, S. A.. And the article was included in Egyptian Journal of Chemistry in 1989.Application In Synthesis of 2-Hydroxy-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione This article mentions the following:
The reaction of N-hydroxy-4-cyclohexene-1,2-dicarboximide with RC6H4COCl (R = H, 4-Me, 4-Cl) gave N-(aroyloxy)-4-cyclohexene-1,2-dicarboximides which reacted with N2H4 or PhNHNH2 to give phthalazinedione derivatives In the experiment, the researchers used many compounds, for example, 2-Hydroxy-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione (cas: 7151-24-8Application In Synthesis of 2-Hydroxy-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione).
2-Hydroxy-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione (cas: 7151-24-8) belongs to indole derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Application In Synthesis of 2-Hydroxy-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione
Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles