Analyzing the synthesis route of 31241-19-7

31241-19-7 5-Methoxy-2,3,3-trimethyl-3H-indole 11095392, aindole-building-block compound, is more and more widely used in various fields.

31241-19-7, 5-Methoxy-2,3,3-trimethyl-3H-indole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A synthetic procedure was based on the literature method [15] with some modifications. A solution of 5-methoxy-2,3,3-trimethyl-3H-indole (0.502 g, 1.60 mmol) and 2-bromoethanol (0.198 g, 2.00 mmol) in MeCN (20 mL) was maintained under N2 and heated under reflux for 1 day. After the mixture was cooled to ambient temperature, the solvent was distilled off under reduced pressure. The resulting solid was recrystallized from CHCl3 (35 mL), then filtered and dried, to afford the targeted compound in high yield (68%)., 31241-19-7

31241-19-7 5-Methoxy-2,3,3-trimethyl-3H-indole 11095392, aindole-building-block compound, is more and more widely used in various fields.

Reference:
Article; Li, Hong; Pang, Meili; Wu, Bianpeng; Meng, Jiben; Journal of Molecular Structure; vol. 1087; (2015); p. 23 – 29;,
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