Synthetic Route of 121-79-9, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 121-79-9, Name is Propyl Gallate, SMILES is O=C(OCCC)C1=CC(O)=C(O)C(O)=C1, belongs to indole-building-block compound. In a article, author is Mitra, Bijeta, introduce new discover of the category.
Humic acid, a biodegradable, non-toxic and easily accessible high molecular weight organocatalyst has been explored for the straightforward and environmentally benign approach towards the preparation of diverse array of functionalized bis(indolyl)methanes, bis(pyrazolyl)methanes, bis-coumarins and bis-lawsones by the reaction of a vast range of aldehydes with indole, 3-methyl-1-phenyl pyrazolone, 4-hydroxycoumarin and 2-hydroxynaphthalene-1,4-dione respectively under solvent-free condition. These protocols proceed without any hazardous solvents, toxic metal catalysts and harsh reaction conditions. In addition, low catalyst loading, good yield and excellent functional group tolerance are the key advantages of these protocols. The used catalyst and solvent-free approach make this strategy safe to our mother earth. For the first time reusability of humic acid was investigated and found that it can be recycled up to fifth run without any significant loss of its activity at the end of the reaction. Some bioactive molecules such as arundine, trisindoline and vibribdole A were easily synthesized in our lab by utilizing this designed strategy.
Synthetic Route of 121-79-9, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 121-79-9.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles