B(C6F5)3-Catalyzed Direct C3 Alkylation of Indoles and Oxindoles was written by Basak, Shyam;Alvarez-Montoya, Ana;Winfrey, Laura;Melen, Rebecca L.;Morrill, Louis C.;Pulis, Alexander P.. And the article was included in ACS Catalysis in 2020.Formula: C10H10BrN This article mentions the following:
A new approach to the direct C3-alkylation of indoles and oxindoles using a B(C6F5)3 catalyst and amine-derived alkylating agents to give arylated indole derivatives I [R = H, Me, n-hexyl, Bn; R1 = H, Me, Ph; R2 = H, 4-Me, 5-Cl, etc.; R3 = Me, Et, Bn, etc.] and oxindole derivatives II [R4 = H, 5-F, 6-Me, etc.; R5 = CO2Et, Ph, 4-MeC6H4, etc.] were reported. Also this borane-catalyzed strategy in alkylation-ring opening cascade process to afford functionalized indoles III [R6 = H, Me; R7 = H, Me; R8 = H, 5-OMe; R9 = 2,4,6-(Me)3C6H2, 2-MeOC6H4, 2-Me-4-MeOC6H3, 2,6-(Me)2-4-MeOC6H2] was reported. In the experiment, the researchers used many compounds, for example, 5-Bromo-2,3-dimethyl-1H-indole (cas: 4583-55-5Formula: C10H10BrN).
5-Bromo-2,3-dimethyl-1H-indole (cas: 4583-55-5) belongs to indole derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Formula: C10H10BrN
Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles