A Bu4N[Fe(CO)3(NO)]-Catalyzed Hemetsberger-Knittel Indole Synthesis was written by Baykal, Aslihan;Plietker, Bernd. And the article was included in European Journal of Organic Chemistry in 2020.Recommanded Product: 210345-56-5 This article mentions the following:
The nucleophilic Fe complex Bu4N[Fe(CO)3(NO)] (TBA[Fe]) catalyzes the direct intramol. amination of aryl vinyl azides RCH=C(N3)C(O)R1 (R = 3,4-dimethoxyphenyl, 4,5-dimethylfuran-2-yl, naphthalen-1-yl, etc.; R1 = Ph, OMe, morpholin-4-yl, etc.) to give the corresponding indole derivatives I (R2 = H, F, CN, dimethylaminyl, etc.; R3 = H, Br, OMe; R4 = H, Br, Me, OMe; R3R4 = -(CH=CH-CH=CH)-; R5 = H, Me), Me 2,3-dimethyl-4H-furo[3,2-b]pyrrole-5-carboxylate and Me pyrazolo[1,5-a]pyridine-2-carboxylate in good to excellent yields. In the experiment, the researchers used many compounds, for example, Methyl 5-bromo-1H-indole-2-carboxylate (cas: 210345-56-5Recommanded Product: 210345-56-5).
Methyl 5-bromo-1H-indole-2-carboxylate (cas: 210345-56-5) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Recommanded Product: 210345-56-5
Referemce:
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Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles