Category: 120-14-9

Quality Control of 3,4-Dimethoxybenzaldehyde. Neacsu, M; Vaughan, NJ; Perri, V; Duncan, GJ; Walker, R; Coleman, M; Russell, WR in [Neacsu, Madalina; Vaughan, Nicholas J.; Perri, Valentina; Russell, Wendy R.] Univ Aberdeen, Rowett Inst, Aberdeen AB25 2ZD, Scotland; [Duncan, Gary J.] Univ Aberdeen, Rowett Inst, Sci Serv, Aberdeen AB25 2ZD, Scotland; [Walker, Robin] SRUC Aberdeen, Craibstone Estate, Aberdeen AB21 9YA, Scotland; [Coleman, Max] Royal Bot Garden Edinburgh, 20A Inverleith Row, Edinburgh EH3 5LR, Midlothian, Scotland published Nutritional and chemical profiling of UK-grown potato bean (Apios americana Medik) reveal its potential for diet biodiversification and revalorisation in 2021.0, Cited 86.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9.

Apios americana Medik, a native American plant has potential as a commercially viable Northern European-grown motcrop, mainly due to its resistance to extreme climate and nutritional quality. Analysis of A. americana sourced from two UK sites; South (51.4690 degrees N, 1.1150 degrees W) and North (55.9661 degrees N, 3.2063 degrees W) showed that the tubers were a complete source of amino acids (UPLC-TUV analysis), were rich in protein (15.0 +/- 0.0160 and 17.3 +/- 0.0779%; Vario Max CN analysis), fibre (total non-starch polysaccharides, 10.4 +/- 0.570 and 10.6 +/- 0.280%; GC analysis) and micronutrients (calcium, manganese, iron, zinc, molybdenum, potassium and phosphorus; ICP-MS analysis). Apios americana tubers were also rich in bioactive phytochemicals. From the 156 plant metabolites measured using LC-MS/MS analysis, genistein was the major phytophenol in both the Southern- and Northern UK tubers (259 +/- 12.2 mg Kg(-1) and 356 +/- 29.9 mg Kg(-1) respectively); the peel having similar phytochemical profiles. The protein and fibre content of the leaves (17.3 +/- 0.0434% and 11.7 0.0445%) and rhizomes (18.4 +/- 0.0152% and 13.5 +/- 0.590%) were significantly higher (p < 0.05) than the tubers. The leaves were also a good source of anthocyanins; delphinidin and cyanidin (840 +/- 137 and 3934 +/- 176 mg Kg(-1) respectively). Cultivation of A. americana as a high-protein staple-crop has enormous potential in Northern European countries for human nutrition, diet diversification, and use in livestock diets. Quality Control of 3,4-Dimethoxybenzaldehyde. Bye, fridends, I hope you can learn more about C9H10O3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: C9H10O3. Authors Kaur, R; Kumar, R; Dogra, N; Kumar, A; Yadav, AK; Kumar, M in FUTURE SCI LTD published article about in [Kaur, Ramandeep; Yadav, Ashok Kumar; Kumar, Manoj] Panjab Univ, Univ Inst Pharmaceut Sci, Chandigarh 160014, India; [Kumar, Rajnish] Indian Inst Technol, Dept Pharmaceut Engn & Technol, Varanasi 221005, Uttar Pradesh, India; [Dogra, Nilambra; Kumar, Ashok] Panjab Univ, Ctr Syst Biol & Bioinformat, Chandigarh 160014, India in 2021, Cited 66. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

Aim: Keeping in view the side effects associated with clinically used alpha-glucosidase inhibitors, novel thiazolidinedione-isatin hybrids were synthesized and evaluated by in vitro, in vivo and in silico procedures. Materials & methods: Biological evaluation, cytotoxicity assessment, molecular docking, binding free energy calculations and molecular dynamics studies were performed for hybrids. Results: The most potent inhibitor A-10 (IC50 = 24.73 +/- 0.93 mu M) was competitive in manner and observed as non-cytotoxic. A-10 possessed higher efficacy than the standard drug (acarbose) during in vivo biological testing. Conclusion: The enzyme inhibitory potential and safety profile of synthetic molecules was recognized after in vitro, in vivo, in silico and cytotoxicity studies. Further structural optimization of A-10 can offer potential hit molecules suitable for future investigations.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Kaur, R; Kumar, R; Dogra, N; Kumar, A; Yadav, AK; Kumar, M or concate me.. HPLC of Formula: C9H10O3

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Preparation of some chromeno[4,3-d]pyrido[1,2-a]pyrimidine derivatives by ultrasonic irradiation using NiFe2O4@SiO2 grafted di(3-propylsulfonic acid) nanoparticles WOS:000655659400001 published article about MAGNETICALLY RETRIEVABLE CATALYSTS; POT MULTICOMPONENT SYNTHESIS; BIOLOGICAL EVALUATION; EFFICIENT; PYRIMIDINE; DESIGN; NANOCOMPOSITE; NANOMATERIALS; OPTIMIZATION; INHIBITORS in [Khalaj, Mehdi] Islamic Azad Univ Buinzahra, Dept Chem, Buinzahra Branch, Buin Zahra, Iran; [Taherkhani, Mahboubeh] Islamic Azad Univ, Coll Sci, Dept Chem, Takestan Branch, Takestan, Iran; [Kalhor, Mehdi] Payame Noor Univ, Dept Organ Chem, Tehran 193954697, Iran in 2021, Cited 44. Formula: C9H10O3. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

NiFe2O4@SiO2 grafted di(3-propylsulfonic acid) was prepared by a facile method and characterized using XRD, FT-IR, SEM-EDX, TGA, and BET techniques. The XRD pattern shows the characteristic peaks of the cubic structure for NiFe2O4. The presence of sulfonic acid groups was confirmed by FT-IR analysis. The catalyst was used for the preparation of chromeno[4,3-d]pyrido[1,2-a]pyrimidine derivatives via the three-component condensation reaction of 4-hydroxycoumarin, aldehydes, and 2-aminopyridines under US irradiation. The effects of solvent, temperature, and catalyst dosage on product formation under the reaction conditions were investigated. The simple procedure, good yields, short reaction times, and catalyst recovery are some of the key advantages of this method.

Bye, fridends, I hope you can learn more about C9H10O3, If you have any questions, you can browse other blog as well. See you lster.. Formula: C9H10O3

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

COA of Formula: C9H10O3. Authors Holota, S; Komykhov, S; Sysak, S; Gzella, A; Cherkas, A; Lesyk, R in MDPI published article about in [Holota, Serhii; Sysak, Stepan; Lesyk, Roman] Danylo Halytsky Lviv Natl Med Univ, Dept Pharmaceut Organ & Bioorgan Chem, Pekarska 69, UA-79010 Lvov, Ukraine; [Holota, Serhii] Lesya Ukrainka Volyn Natl Univ, Dept Organ Chem & Pharm, Volya Ave 13, UA-43025 Lutsk, Ukraine; [Komykhov, Sergiy] Natl Acad Sci Ukraine, Inst Single Crystals, State Sci Inst, Nauky Ave 60, UA-61072 Kharkiv, Ukraine; [Komykhov, Sergiy] Kharkov Natl Univ, Appl Chem Dept, Svobody Sq 4, UA-61022 Kharkiv, Ukraine; [Gzella, Andrzej] Poznan Univ Med Sci, Dept Organ Chem, Grunwaldzka 6, PL-60780 Poznan, Poland; [Cherkas, Andriy] Danylo Halytsky Lviv Natl Med Univ, Dept Internal Med 1, Pekarska 69, UA-79010 Lvov, Ukraine; [Lesyk, Roman] Univ Informat Technol & Management Rzeszow, Fac Med, Dept Publ Hlth Dietet & Lifestyle Disorders, Sucharskiego 2, PL-35225 Rzeszow, Poland; [Cherkas, Andriy] Sanofi Aventis Deutschland GmbH, Team Early Projects Type Diabet 1, Therapeut Area Diabet & Cardiovasc Med, Res & Dev, Ind Pk Hochst H831, D-65926 Frankfurt, Germany in 2021.0, Cited 55.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

The present paper is devoted to the search for drug-like molecules with anticancer properties using the thiazolo[3,2-b][1,2,4]triazole-6-one scaffold. A series of 24 novel thiazolo-[3,2-b][1,2,4]triazole-6-ones with 5-aryl(heteryl)idene- and 5-aminomethylidene-moieties has been synthesized employing three-component and three-stage synthetic protocols. A mixture of Z/E-isomers was obtained in solution for the synthesized 5-aminomethylidene-thiazolo[3,2-b]-[1,2,4]triazole-6-ones. The compounds have been studied for their antitumor activity in the NCI 60 lines screen. Some compounds present excellent anticancer properties at 10 mu M. Derivatives 2h and 2i were the most active against cancer cell lines without causing toxicity to normal somatic (HEK293) cells. A preliminary SAR study had been performed for the synthesized compounds.

COA of Formula: C9H10O3. Welcome to talk about 120-14-9, If you have any questions, you can contact Holota, S; Komykhov, S; Sysak, S; Gzella, A; Cherkas, A; Lesyk, R or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Formula: C9H10O3. Authors Kumar, M; Joshi, G; Arora, S; Singh, T; Biswas, S; Sharma, N; Bhat, ZR; Tikoo, K; Singh, S; Kumar, R in MDPI published article about in [Kumar, Manvendra; Joshi, Gaurav; Arora, Sahil; Biswas, Sajal; Kumar, Raj] Cent Univ Punjab, Sch Hlth Sci, Dept Pharmaceut Sci & Nat Prod, Lab Drug Design & Synth, Bathinda 151401, Punjab, India; [Joshi, Gaurav] Graph Era Hill Univ, Sch Pharm, Dehra Dun 248171, Uttarakhand, India; [Singh, Tashvinder; Singh, Sandeep] Cent Univ Punjab, Dept Human Genet & Mol Med, Bathinda 151401, Punjab, India; [Sharma, Nisha; Bhat, Zahid Rafiq; Tikoo, Kulbhushan] Natl Inst Pharmaceut Educ & Res, Dept Pharmacol & Toxicol, Sas Nagar 160062, Punjab, India in 2021.0, Cited 33.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

A series of 30 non-covalent imidazo[1,2-a]quinoxaline-based inhibitors of epidermal growth factor receptor (EGFR) were designed and synthesized. EGFR inhibitory assessment (against wild type) data of compounds revealed 6b, 7h, 7j, 9a and 9c as potent EGFR(WT) inhibitors with IC50 values of 211.22, 222.21, 193.18, 223.32 and 221.53 nM, respectively, which were comparable to erlotinib (221.03 nM), a positive control. Furthermore, compounds exhibited excellent antiproliferative activity when tested against cancer cell lines harboring EGFR(WT); A549, a non-small cell lung cancer (NSCLC), HCT-116 (colon), MDA-MB-231 (breast) and gefitinib-resistant NSCLC cell line H1975 harboring EGFR(L858R/T790M). In particular, compound 6b demonstrated significant inhibitory potential against gefitinib-resistant H1975 cells (IC50 = 3.65 mu M) as compared to gefitinib (IC50 > 20 mu M). Moreover, molecular docking disclosed the binding mode of the 6b to the domain of EGFR (wild type and mutant type), indicating the basis of inhibition. Furthermore, its effects on redox modulation, mitochondrial membrane potential, cell cycle analysis and cell death mode in A549 lung cancer cells were also reported.

Formula: C9H10O3. Welcome to talk about 120-14-9, If you have any questions, you can contact Kumar, M; Joshi, G; Arora, S; Singh, T; Biswas, S; Sharma, N; Bhat, ZR; Tikoo, K; Singh, S; Kumar, R or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 120-14-9. Authors Mohamadpour, F in SPRINGER WIEN published article about in [Mohamadpour, Farzaneh] Apadana Inst Higher Educ, Sch Engn, Shiraz, Iran in 2021.0, Cited 32.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

Catalyst-free and solvent-free three-component tandem approach can synthesize 2-amino-4H-chromene scaffolds by Knoevenagel-Michael cyclocondensation of aryl aldehydes, malononitrile, and resorcinol via visible light irradiation as a green promoter at room temperature. The significant advantages of the present protocol include energy-effectiveness, catalyst-free, excellent yields, solvent-free, operational simplicity, and high atom-economy, commercially accessible inexpensive preliminary substances, so it meets some features of sustainable and green chemistry.

SDS of cas: 120-14-9. Welcome to talk about 120-14-9, If you have any questions, you can contact Mohamadpour, F or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 120-14-9. Recently I am researching about DERIVATIVES, Saw an article supported by the . Published in BENTHAM SCIENCE PUBL LTD in SHARJAH ,Authors: Suryawanshi, VB; Momin, KI; Dawle, JK; Mathapati, SR. The CAS is 120-14-9. Through research, I have a further understanding and discovery of 3,4-Dimethoxybenzaldehyde

Solvent free synthesis of dihydropyrano[3,2-b]chromenediones was formulated via multicomponent reactions of kojic acid, dimedone and several substituted aromatic aldehydes catalyzed with BCl3. Reactions progressed efficiently and the corresponding heterocyclic products were obtained in good to high yields within short period. The developed protocol is one of the better and efficient alternative methods for the synthesis of dihydropyrano[3,2-b]chromenediones. The simple reaction procedure, easy separation of products, radially available catalyst are certain benefits of this reported protocol.

Welcome to talk about 120-14-9, If you have any questions, you can contact Suryawanshi, VB; Momin, KI; Dawle, JK; Mathapati, SR or send Email.. SDS of cas: 120-14-9

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Shaibuna, M; Sreekumar, K in TAYLOR & FRANCIS INC published article about in [Shaibuna, M.; Sreekumar, K.] Cochin Univ Sci & Technol, Dept Appl Chem, Cochin, Kerala, India in 2021.0, Cited 44.0. Safety of 3,4-Dimethoxybenzaldehyde. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

Deep eutectic solvents are a class of new generation green solvents formed from two or more components, which furnish a new homogeneous liquid phase with lower melting point than the individual components. Here, for the first time, dual role of DES as catalyst and reaction medium was studied for the synthesis of symmetric dihydropyridine derivatives from aldehyde, ethyl acetoacetate and ammonium acetate. The present article reports the suitability of six DESs for Hantzsch dihydropyridine synthesis at room temperature. Among this, DES 2 (ZrOCl2.8H(2)O and ethylene glycol at 1:2 ratio) was found to be the catalyst of choice with excellent recyclability. The role of DES in the present protocol was to activate the reactants through strong hydrogen bonding interaction and provide suitable medium for the reaction. The major advantages of DESs for the titled reaction are the easy preparation, low cost, non-volatility, biodegradability, simple catalytic process, excellent conversion and the reusability.

Safety of 3,4-Dimethoxybenzaldehyde. Bye, fridends, I hope you can learn more about C9H10O3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

COA of Formula: C9H10O3. In 2021.0 RSC ADV published article about THIACROWN ETHERS; X-RAY; COMPLEXATION; MALONONITRILE; DERIVATIVES; SCAFFOLDS; BEHAVIOR; SULFUR in [Akhmadiev, Nail S.; Mescheryakova, Ekaterina S.; Akhmetova, Vnira R.; Ibragimov, Askhat G.] Russian Acad Sci, Inst Petrochem & Catalysis, 141 Praspekt Octyabrya, Ufa 450075, Russia in 2021.0, Cited 37.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9.

The first synthesis of 5,12-diamino-7,14-bis(aryl)-1,4,8,11-tetrathiacyclotetradeca-5,12-diene-6,13-dicarbonitriles was performed as a multicomponent macroheterocyclization of malononitrile, aryl aldehydes, and 1,2-ethanedithiol in the presence of a catalytic amount of triethylamine in ethanol. The structures of the obtained macroheterocycles were confirmed by spectral methods, X-ray diffraction, and MALDI TOF mass spectrometry.

Bye, fridends, I hope you can learn more about C9H10O3, If you have any questions, you can browse other blog as well. See you lster.. COA of Formula: C9H10O3

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Pfeffer, C; Wannenmacher, N; Frey, W; Peters, R in AMER CHEMICAL SOC published article about TO-HEAD DIMERIZATION; NONAROMATIC CATECHOL BIOISOSTERES; AZA-CLAISEN REARRANGEMENT; TERMINAL ARYL ALKYNES; CONJUGATED ENYNES; SELECTIVE DIMERIZATION; CATALYZED DIMERIZATION; PALLADIUM COMPLEXES; TAIL DIMERIZATION; PALLADACYCLE in [Pfeffer, Camilla; Wannenmacher, Nick; Frey, Wolfgang; Peters, Rene] Univ Stuttgart, Inst Organ Chem, D-70569 Stuttgart, Germany in 2021, Cited 69. Application In Synthesis of 3,4-Dimethoxybenzaldehyde. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

Enynes are important motifs in bioactive compounds. They can be synthesized by alkyne-alkyne couplings for which a number of mechanisms have been suggested depending on catalyst type and dominant product isomers. Regarding bimetallic pathways, hydrometalations and anti-carbopalladations have been discussed to account for the formation of geminally substituted and (Z)-configured enynes, respectively. Here we report a bimetallic alkyne-alkyne coupling that yields (E)-configured enynes. An unusual type of acetylide Pd bridging was found in putative catalytic intermediates which is arguably responsible for the regio- and stereochemical reaction outcome. Mechanistic studies suggest that a double mu-kappa:eta(2) acetylide bridging enables a bimetallic syn-carbometalation. Interestingly, depending on the reaction conditions, it is also possible to form the geminal regioisomer as major product with the same catalyst. This regiodivergent outcome is explained by bi-versus monometallic reaction pathways.

Application In Synthesis of 3,4-Dimethoxybenzaldehyde. Welcome to talk about 120-14-9, If you have any questions, you can contact Pfeffer, C; Wannenmacher, N; Frey, W; Peters, R or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles