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About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Iioka, R; Yorozu, K; Sakai, Y; Kawai, R; Hatae, N; Takashima, K; Tanabe, G; Wasada, H; Yoshimatsu, M or concate me.. Quality Control of 3,4-Dimethoxybenzaldehyde

In 2021.0 EUR J ORG CHEM published article about C-H ACTIVATION; NITRENE INSERTIONS; INDOLE ALKALOIDS; CYCLOADDITION; CONSTRUCTION; INHIBITORS; DISCOVERY; DERIVATIVES; ANTAGONISTS; CARBOLINES in [Iioka, Ryoya; Yorozu, Kohei; Sakai, Yoko; Kawai, Rika; Yoshimatsu, Mitsuhiro] Gifu Univ, Fac Educ, Dept Chem, Yanagido 1-1, Gifu 5011193, Japan; [Hatae, Noriyuki] Yokohama Univ Pharm, Fac Pharmaceut Sci, Totsuka Ku, 601 Matano, Yokohama, Kanagawa 2450066, Japan; [Takashima, Katsuki; Tanabe, Genzoh] Kinki Univ, Fac Pharm, 3-4-1 Kowakae, Higashiosaka, Osaka 5778502, Japan; [Wasada, Hiroaki] Gifu Univ, Fac Reg Study, Dept Chem, Yanagido 1-1, Gifu 5011193, Japan in 2021.0, Cited 81.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9. Quality Control of 3,4-Dimethoxybenzaldehyde

Lewis acid-catalyzed [6+1] annulation reactions of 2-cyano-1-propargyl- and 2-alkynyl-1-cyanomethyl-indoles with Reformatsky reagent are described. 8-Aryl, 8-alkyl-, 8-hetaryl-, 9-aryl, and 9-alkyl-azepino[1,2-a]indole amines were obtained through a 7-endo-mode cyclization of the beta-aminoacrylate intermediates. The antiproliferative activity of the azepino[1,2-a]indoles analogs against the HCT-116 cells were also examined.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Iioka, R; Yorozu, K; Sakai, Y; Kawai, R; Hatae, N; Takashima, K; Tanabe, G; Wasada, H; Yoshimatsu, M or concate me.. Quality Control of 3,4-Dimethoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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HPLC of Formula: C9H10O3. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Yadav, U; Vanjari, Y; Laxmikeshav, K; Tokala, R; Niggula, PK; Kumar, M; Talla, V; Kamal, A; Shankaraiah, N or concate me.

HPLC of Formula: C9H10O3. Authors Yadav, U; Vanjari, Y; Laxmikeshav, K; Tokala, R; Niggula, PK; Kumar, M; Talla, V; Kamal, A; Shankaraiah, N in BENTHAM SCIENCE PUBL LTD published article about in [Yadav, Upasana; Vanjari, Yogesh; Laxmikeshav, Kritika; Tokala, Ramya; Niggula, Praveen K.; Shankaraiah, Nagula] Natl Inst Pharmaceut Educ & Res NIPER, Dept Med Chem, Hyderabad 500037, India; [Kumar, Manoj; Talla, Venu] Natl Inst Pharmaceut Educ & Res NIPER, Dept Pharmacol & Toxicol, Hyderabad 500037, India; [Kamal, Ahmed] Jamia Hamdard, Sch Pharmaceut Educ & Res SPER, New Delhi 110062, India in 2021, Cited 66. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

Objective: To synthesize a series of phenanthrene-thiazolidinedione hybrids and explore their cytotoxic potential against human cancer cell lines of A-549 (lung cancer), HCT-116 and HT-29 (colon cancer), MDA MB-231 (triple-negative breast cancer), BT-474 (breast cancer) and (mouse melanoma) B16F10 cells. Methods: A new series of phenanthrene-thiazolidinedione hybrids was synthesized via Knoevenagel condensation of phenanthrene-9-carbaldehyde and N-alkylated thiazolidinediones. The cytotoxicity (IC50) of the synthesized compounds was determined by MTT assay. Apoptotic assays like (AO/EB) and DAPI staining, cell cycle analysis, JC-1 staining and Annexin V binding assay studies were performed for the most active compound (Z)- 3-(4-bromobenzyl)-5-((2,3,6,7-tetramethoxyphenanthren-9-yl)methylene)thiazolidine-2,4-dione (17b). Molecular docking, dynamics and evaluation of pharmacokinetic (ADME/T) properties were also carried out by using Schrodinger. Results and Discussion: From the series of tested compounds, 17b unveiled promising cytotoxic action with an IC50 value of 0.985 +/- 0.02 mu M on HCT-116 human colon cancer cells. The treatment of HCT-116 cells with 17b demonstrated distinctive apoptotic morphology like shrinkage of cells, horseshoe-shaped nuclei formation and chromatin condensation. The flow-cytometry analysis revealed the G(0)/G(1) phase cell cycle arrest in a dosedependent fashion. The AO/EB, DAPI, DCFDA, Annexin-V and JC-1 staining studies were performed in order to determine the effect of the compound on cell viability. Computational studies were performed by using Schrodinger to determine the stability of the ligand with the DNA. Conclusion: The current study provides an insight into developing a series of phenanthrene thiazolidinedione derivatives as potential DNA interactive agents which might aid in colon cancer therapy.

HPLC of Formula: C9H10O3. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Yadav, U; Vanjari, Y; Laxmikeshav, K; Tokala, R; Niggula, PK; Kumar, M; Talla, V; Kamal, A; Shankaraiah, N or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Aziz, MW; Kamal, AM; Mohamed, KO; Elgendy, AA or concate me.. Safety of 3,4-Dimethoxybenzaldehyde

An article Design, synthesis and assessment of new series of quinazolinone derivatives as EGFR inhibitors along with their cytotoxic evaluation against MCF7 and A549 cancer cell lines WOS:000651228800015 published article about GROWTH-FACTOR RECEPTOR; BIOLOGICAL EVALUATION in [Aziz, Marian W.; Elgendy, Adel A.] Misr Int Univ, Fac Pharm, Dept Pharmaceut Chem, Cairo, Egypt; [Kamal, Aliaa M.; Mohamed, Khaled O.] Cairo Univ, Fac Pharm, Dept Pharmaceut Organ Chem, Cairo, Egypt; [Kamal, Aliaa M.] October Univ Modern Sci & Arts MSA, Fac Pharm, Dept Pharmaceut Chem, Giza, Egypt in 2021.0, Cited 43.0. Safety of 3,4-Dimethoxybenzaldehyde. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

New acetamide (IV a-e) and 1,3-thiazolidinone derivatives (VII a-e) were designed, synthesized and assessed for their cytotoxic activity against MCF-7 and A549 cell lines along with their lead compounds (erlotinib and gefitinib). The newly designed compounds were prepared according to the adopted procedures in schemes 1 and 2 from their quinazolinone parents. 3D QSAR pharmacophore and docking molecular modeling protocols were conducted using Discovery Studio program, beside a full biological assay for these compounds. The cytotoxicity evaluation demonstrated that compounds IVb, IVc, VIIa, VIIb, VIId exhibited potent cytotoxic activities against both MCF-7 and A549 cell lines. Moreover, the molecular modeling studies corroborated to the affinity of the compounds towards EGFR. Consequently, these five compounds were then screened for their EGFR inhibition and evaluated as well for their toxicity to normal cells, which revealed that the acetamide derivative IVc and the thiazolidinone derivative VIIa were the most potent and least toxic. DNA flow cytometry analysis was conducted for compounds IVc and VIIa, which indicated that they both induced arrest at G2/M phase of the cell cycle.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Aziz, MW; Kamal, AM; Mohamed, KO; Elgendy, AA or concate me.. Safety of 3,4-Dimethoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Milovic, E; Jankovic, N; Vranes, M; Stefanovic, S; Petronijevic, J; Joksimovic, N; Muskinja, J; Ratkovic, Z or concate me.. Recommanded Product: 3,4-Dimethoxybenzaldehyde

Recommanded Product: 3,4-Dimethoxybenzaldehyde. Milovic, E; Jankovic, N; Vranes, M; Stefanovic, S; Petronijevic, J; Joksimovic, N; Muskinja, J; Ratkovic, Z in [Milovic, Emilija; Petronijevic, Jelena; Joksimovic, Nenad; Ratkovic, Zoran] Univ Kragujevac, Fac Sci, Dept Chem, Radoja Domanovica 12, Kragujevac 34000, Serbia; [Jankovic, Nenad; Muskinja, Jovana] Univ Kragujevac, Inst Informat Technol Kragujevac, Dept Sci, Kragujevac 34000, Serbia; [Vranes, Milan] Univ Novi Sad, Fac Sci, Dept Chem Biochem & Environm Protect, Trg Dositeja Obradovica 3, Novi Sad 21000, Serbia; [Stefanovic, Srdan] Inst Meat Hyg & Technol, Kacanskog 13, Belgrade 11000, Serbia published Green one-pot synthesis of pyrido-dipyrimidine DNA-base hybrids in water in 2021.0, Cited 67.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9.

Reactions in water as a safe and cheap solvent is a major goal of green chemistry. Actual synthesis of pyrido-dipyrimidine scaffold, named DNA-base hybrids, involves catalysis in hazardous solvents. Here we synthesised pyrido-dipyrimidines by one-pot heterocyclization of thiobarbituric acid, vanillic aldehydes and amines in water. Enamine and vanillidene are key intermediates of the Biginelli-like reaction mechanism. Our synthetic method displays several benefits such as the use of a green medium and various substrates, and yields up to 99%.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Milovic, E; Jankovic, N; Vranes, M; Stefanovic, S; Petronijevic, J; Joksimovic, N; Muskinja, J; Ratkovic, Z or concate me.. Recommanded Product: 3,4-Dimethoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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HPLC of Formula: C9H10O3. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Chauhan, DS; Quraishi, MA; Qurashi, A or concate me.

Authors Chauhan, DS; Quraishi, MA; Qurashi, A in ELSEVIER published article about in [Chauhan, Dheeraj Singh; Quraishi, M. A.] King Fahd Univ Petr & Minerals, Ctr Res Excellence Corros, Res Inst, Dhahran 31261, Saudi Arabia; [Qurashi, Ahsanulhaq] Khalifa Univ Sci & Technol, Dept Chem, Main Campus,POB 127788, Abu Dhabi, U Arab Emirates in 2021.0, Cited 133.0. HPLC of Formula: C9H10O3. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

The oil and gas industry suffers from severe economic impact due to the corrosion of pipelines during the industrial oil-well acidizing process and because of the sweet corrosion of steel. One of the most common solutions to counter this issue is applying organic compounds as corrosion inhibitors. Conventionally used inhibitors are quite cumbersome to synthesize, are costly, and most are toxic. Therefore, there exists a need for research and development of novel, cost-effective, and eco-friendly corrosion inhibitors showing efficient inhibition performance. The present work describes the basics of corrosion, its economic impact, and the main strategies to counter this issue. Fundamentals of sweet corrosion, the mechanism involved, the influence of various governing factors, and the limitations of the existing inhibitor chemistries are explained. Some of the prominent classes of the environmentally benign sweet corrosion inhibitors such as the biopolymers, heterocyclic molecules, and pharmaceutical products are also outlined. The focus is on the recent research work in this area, and some of the prospective research aspects are envisaged. (C) 2020 Published by Elsevier B.V.

HPLC of Formula: C9H10O3. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Chauhan, DS; Quraishi, MA; Qurashi, A or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Pugachev, MV; Pavelyev, RS; Nguyen, TNT; Gabbasova, RR; Bulatov, TM; Iksanova, AG; Aljondi, B; Bondar, OV; Grishaev, DY; Yamaleeva, ZR; Kataeva, ON; Nikishova, TV; Balakin, KV; Shtyrlin, YG or concate me.. Recommanded Product: 3,4-Dimethoxybenzaldehyde

Authors Pugachev, MV; Pavelyev, RS; Nguyen, TNT; Gabbasova, RR; Bulatov, TM; Iksanova, AG; Aljondi, B; Bondar, OV; Grishaev, DY; Yamaleeva, ZR; Kataeva, ON; Nikishova, TV; Balakin, KV; Shtyrlin, YG in PERGAMON-ELSEVIER SCIENCE LTD published article about PHOSPHONIUM SALTS in [Pugachev, Mikhail, V; Pavelyev, Roman S.; Nguyen, Thang N. T.; Gabbasova, Raylya R.; Bulatov, Timur M.; Iksanova, Alfiya G.; Aljondi, Bashar; Bondar, Oksana, V; Grishaev, Denis Yu; Nikishova, Tatyana, V; Balakin, Konstantin, V; Shtyrlin, Yurii G.] Kazan Volga Reg Fed Univ, Kremlyovskaya 18, Kazan 420008, Russia; [Yamaleeva, Zilya R.; Kataeva, Olga N.] RAS, AE Arbuzov Inst Organ & Phys Chem, FRC Kazan Sci Ctr, Arbuzov Str 8, Kazan 420088, Russia in 2021.0, Cited 26.0. Recommanded Product: 3,4-Dimethoxybenzaldehyde. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

A new efficient approach to the synthesis of 6-alkenyl substituted pyridoxine derivatives has been developed. A series of 31 novel alkenyl pyridoxine derivatives, stilbene-based bioisosteric analogs of estradiol, were synthesized. In vitro cytotoxicity of the obtained compounds against MCF-7 (ER+) breast cancer tumor cells was studied using the MTT assay. The most active compounds with IC50, MCF-7 < 10 mu M were also tested for cytotoxicity in vitro against MDA-MB-231 (ER-) breast adenocarcinoma cells and conditionally normal human skin fibroblasts (HSF). The patterns of structure-antitumor activity relationships of the obtained compounds were analyzed. The most active compounds were found to contain a six-membered ketal ring, a methyl group in position 5, a 3,4-dimethoxystyryl fragment in positions 2 or 6 of the pyridoxine ring, and a trans-configuration of the double bond. Using the most active compound 5a as a representative cytotoxic agent, we have demonstrated that it has high specificity and antiproliferative activity against MCF-7 (ER+) tumor cells (IC50 < 5 mu M), and a higher therapeutic index compared to the reference compound raloxifene (48 versus 5.8). Compound 5a decreased the mitochondrial membrane potential and increased the level of reactive oxygen species in MCF-7 cells, but not MDA-MB-231 cells. Compound 5a did not affect the distribution of cell cycle phases and induced apoptosis in MCF-7 cells, but not MDA-MB-231. Unlike compound 5a, raloxifene decreased mitochondrial potential, increased the ROS level, and induced apoptosis in both MCF-7 and MDA-MB-231 cells, which indicated a lack of selectivity for cells with estrogen receptor expression. It was also shown that compound 5a reduced the level of ER alpha expression in cells to a lesser extent than raloxifene and, unlike the latter, did not activate the PI3K/Akt signaling pathway. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Pugachev, MV; Pavelyev, RS; Nguyen, TNT; Gabbasova, RR; Bulatov, TM; Iksanova, AG; Aljondi, B; Bondar, OV; Grishaev, DY; Yamaleeva, ZR; Kataeva, ON; Nikishova, TV; Balakin, KV; Shtyrlin, YG or concate me.. Recommanded Product: 3,4-Dimethoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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Recommanded Product: 3,4-Dimethoxybenzaldehyde. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Hajjami, M; Sheikhaei, S; Gholamian, F; Yousofvand, Z or concate me.

An article Synthesis and Characterization of Magnetic Functionalized Ni and Cu Nano Catalysts and Their Application in Oxidation, Oxidative Coupling and Various Multi-Component Reactions WOS:000604191500004 published article about ONE-POT SYNTHESIS; RECYCLABLE CATALYST; EFFICIENT CATALYST; 5-SUBSTITUTED 1H-TETRAZOLES; SELECTIVE OXIDATION; HYDROGEN-PEROXIDE; IRON-OXIDE; NANOPARTICLES; SULFIDES; COMPLEX in [Hajjami, Maryam] Bu Ali Sina Univ, Dept Organ Chem, Fac Chem, Hamadan 6517838683, Hamadan, Iran; [Sheikhaei, Shiva; Gholamian, Fatemeh; Yousofvand, Zakieh] Ilam Univ, Fac Sci, Dept Chem, POB 69315516, Ilam, Iran in 2021.0, Cited 47.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9. Recommanded Product: 3,4-Dimethoxybenzaldehyde

Two magnetic nano catalysts of nickel and copper, Fe3O4@SiO2@DOP-BenPyr-M(II), (M=Ni and Cu) have been synthesized. These catalysts were applied as recoverable, efficient and new heterogeneous catalysts for the high yielding and room temperature one-pot procedure of selective oxidation of sulfides to sulfoxides and oxidative coupling of thiols to disulfides. In addition, the catalytic activity of Fe3O4@SiO2@DOP-BenPyr-Ni(II) was investigated as heterogeneous nanocatalyst for synthesis of 2,3-dihydroquinazolin-4(1H)-ones, 5-substituted 1H-tetrazoles and polyhydroquinolines. The synthesized catalysts were characterized by FT-IR, TGA, XRD, VSM, EDX, ICP and SEM techniques. These catalysts were recovered by an external magnet and reused several times without significant loss of catalytic efficiency. [GRAPHICS] .

Recommanded Product: 3,4-Dimethoxybenzaldehyde. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Hajjami, M; Sheikhaei, S; Gholamian, F; Yousofvand, Z or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Yang, BW; Zuo, LH; Chang, XW; Liu, T; Cui, MY; Liu, Y; Sun, HY; Chen, WP; Guo, WS or concate me.. Application In Synthesis of 3,4-Dimethoxybenzaldehyde

An article Kinetically Controllable Pd-Catalyzed Decarboxylation Enabled [5+2] and [3+2] Cycloaddition toward Carbocycles Featuring Quaternary Carbons WOS:000643163800019 published article about ENANTIOSELECTIVE CONSTRUCTION; VINYLETHYLENE CARBONATES; NAZAROV CYCLIZATION; BOND; DESYMMETRIZATION; HETEROCYCLES; REACTIVITY; ALCOHOL; CENTERS; SYSTEM in [Yang, Biwei; Zuo, Linhong; Chang, Xiaowei; Liu, Teng; Cui, Manying; Liu, Yang; Sun, Haiyu; Chen, Weipeng; Guo, Wusheng] Xi An Jiao Tong Univ, Frontier Inst Sci & Technol FIST, Xian 710045, Peoples R China in 2021.0, Cited 71.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9. Application In Synthesis of 3,4-Dimethoxybenzaldehyde

A decarboxylative protocol has been developed toward a range of carbocycles. The key success is based on the use of a batch of newly designed cyclic carbonates as substrates that can provide carbon-carbon zwitterion intermediate under palladium catalysis. The kinetics of the reactions are controllable toward either strained seven- or thermodynamically more favored five-membered carbocycles. The release of this chemistry will shed light on the synthesis of complex and valuable cyclic structures.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Yang, BW; Zuo, LH; Chang, XW; Liu, T; Cui, MY; Liu, Y; Sun, HY; Chen, WP; Guo, WS or concate me.. Application In Synthesis of 3,4-Dimethoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Duan, SZ; Deng, GG; Zi, YJ; Wu, XM; Tian, X; Liu, ZF; Li, MY; Zhang, HB; Yang, XD; Walsh, PJ or concate me.. SDS of cas: 120-14-9

SDS of cas: 120-14-9. Authors Duan, SZ; Deng, GG; Zi, YJ; Wu, XM; Tian, X; Liu, ZF; Li, MY; Zhang, HB; Yang, XD; Walsh, PJ in ROYAL SOC CHEMISTRY published article about in [Duan, Shengzu; Deng, Guogang; Zi, Yujin; Wu, Xiaomei; Tian, Xun; Liu, Zhengfen; Zhang, Hongbin; Yang, Xiaodong] Yunnan Univ, Sch Chem Sci & Technol, Yunnan Prov Ctr Res & Dev Nat Prod, Key Lab Med Chem Nat Resource,Minist Educ, Kunming 650091, Yunnan, Peoples R China; [Li, Minyan; Walsh, Patrick J.] Univ Penn, Dept Chem, Penn Merck Lab High Throughput Expt, Roy & Diana Vagelos Labs, 231 South 34th St, Philadelphia, PA 19104 USA in 2021.0, Cited 67.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

A unique enantioselective nickel-catalyzed vinylation of 2-azaallyl anions is advanced for the first time. This method affords diverse vinyl aryl methyl amines with high enantioselectivities, which are frequently occurring scaffolds in natural products and medications. This C-H functionalization method can also be extended to the synthesis of enantioenriched 1,3-diamine derivatives by employing suitably elaborated vinyl bromides. Key to the success of this process is the identification of a Ni/chiraphos catalyst system and a less reducing 2-azaallyl anion, all of which favor an anionic vinylation route over a background radical reaction. A telescoped gram scale synthesis and a product derivatization study confirmed the scalability and synthetic potential of this method.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Duan, SZ; Deng, GG; Zi, YJ; Wu, XM; Tian, X; Liu, ZF; Li, MY; Zhang, HB; Yang, XD; Walsh, PJ or concate me.. SDS of cas: 120-14-9

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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COA of Formula: C9H10O3. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Chen, L; Lin, ZY; Zhang, XF; Tan, LS; Zhang, M; Li, YB or concate me.

Chen, L; Lin, ZY; Zhang, XF; Tan, LS; Zhang, M; Li, YB in [Chen, Lu; Lin, Zhenyuan; Zhang, Xuefang; Tan, Leshi; Zhang, Min; Li, Yibiao] Wuyi Univ, Sch Biotechnol & Hlth Sci, Jiangmen, Peoples R China published Catalyst-free visible-light induced synthesis of nitrogen- and oxygen-containing heterocycles from 1,3-diketones in 2021.0, Cited 40.0. COA of Formula: C9H10O3. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9.

The synthesis of nitrogen- and oxygen-containing heterocycles has found many applications in the preparation of biomedical intermediates, yet actual synthetic procedures display limitations such as high-loading catalysts, harsh reaction conditions and tedious preparation of heterogeneous catalysts. Alternatively, photocatalysis allows to access functional products with minimum synthetic procedures and waste generation. Here, we present an efficient, simple, green protocol for the synthesis of N- and O-containing six-membered-ring compounds under mild conditions under visible blue light. Various aldehydes and 1,3-diketones can be reacted to afford eight series of corresponding 1,4-dihydropyridines and 4H-benzo[b]pyrans. This protocol has some merits such as the use of abundant and sustainable aqueous ethanol as solvent, short reaction time (within 60 min), no need of catalyst and broad functional group tolerance to afford 81 different series of target molecules in 75-96% yield under mild conditions.

COA of Formula: C9H10O3. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Chen, L; Lin, ZY; Zhang, XF; Tan, LS; Zhang, M; Li, YB or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles