Category: 120-14-9

An article Design and synthesis of quinoline-pyrimidine inspired hybrids as potential plasmodial inhibitors WOS:000643683200007 published article about MOLECULAR-DYNAMICS; ASSAY in [Kayamba, Francis; Kushwaha, Narva Deshwar; Mahlalela, Mavela; Karpoormath, Rajshekhar] Univ KwaZulu Natal, Coll Hlth Sci, Dept Pharmaceut Chem, ZA-4000 Durban, South Africa; [Malimabe, Teboho; van Zyl, Robyn L.] Univ Witwatersrand, Fac Hlth Sci, Dept Pharm & Pharmacol, Pharmacol Div, ZA-2193 Johannesburg, South Africa; [Malimabe, Teboho; van Zyl, Robyn L.] Univ Witwatersrand, Fac Hlth Sci, WITS Res Inst Malaria WRIM, ZA-2193 Johannesburg, South Africa; [Ademola, Idowu Kehinde; Gordon, Michelle] Univ KwaZulu Natal, Coll Hlth Sci, Sch Lab Med & Med Sci, ZA-4000 Durban, South Africa; [Pooe, Ofentse Jacob] Univ KwaZulu Natal, Sch Life Sci, Discipline Biochem, ZA-4000 Durban, South Africa; [Mudau, Pertunia T.; Zininga, Tawanda] Univ Venda, Sch Math & Nat Sci, Dept Biochem, ZA-0950 Thohoyandou, South Africa; [Zininga, Tawanda; Shonhai, Addmore] Stellenbosch Univ, Dept Biochem, ZA-7600 Stellenbosch, South Africa; [Nyamori, Vincent O.] Univ KwaZulu Natal, Sch Chem & Phys, Westville Campus, ZA-4000 Durban, South Africa in 2021, Cited 43. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9. Application In Synthesis of 3,4-Dimethoxybenzaldehyde

Presently, artemisinin-based combination therapy (ACT) is the first-line therapy of Plasmodium falciparum malaria. With the emergence of malaria parasites that are resistant to ACT, alternative antimalarial therapies are urgently needed. In line with this, we designed and synthesised a series of novel N-(7chloroquinolin-4-yl)-N’-(4,6-diphenylpyrimidin-2-yl)alkanediamine hybrids (6a-7c) and evaluated their inhibitory activity against the NF54 chloroquine-susceptible strain as a promising class of antimalarial compounds. The antiplasmodial screening revealed that seven analogues showed promising to good activity with half-maximal inhibitory concentration ( IC50) = 0.32 mu Me4.30 mM. Compound 7a with 1,4-diamine butyl linker and 4-hydroxyl phenyl on fourth and sixth position of pyrimidine core showed the most prominent activity with an IC50 value of 0.32 +/- 0.06 mM, with a favourable safety profile of 9.79 to human kidney epithelial (HEK293) cells. The remaining six analogues showed moderate activity with IC50 values ranging from 7.50 mM to 83.01 mM. We further investigated the binding affinities of the molecules to two essential cytosolic P. falciparum heat shock protein 70 homologues; PfHsp70-1 and PfHsp70-z. Compound 7a exhibited the highest binding affinity for both PfHsp70s with K-D in a lower nanomolar range (4.4-11.4 nM). Furthermore, molecular docking revealed that compounds 6, 6k, 7b and 7a exhibited better fitness in PfHsp70-1 with compound 7a showing the highest and lowest binding scores of similar to 9.8 kcal/mol. Therefore, we speculate that PfHsp70-1 is one of the targets of these inhibitors. The bioisoteric replacement of the groups at phenyl ring at the fourth and sixth position of the pyrimidine core had a constructive association with antiplasmodial activity. The promising antiplasmodial activity of the synthesised analogues illustrates how crucial molecular hybridisation is as a strategy in the development of quinoline-pyrimidine hybrids as prospective antiprotozoal agents. (C) 2021 Elsevier Masson SAS. All rights reserved.

Application In Synthesis of 3,4-Dimethoxybenzaldehyde. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Kayamba, F; Malimabe, T; Ademola, IK; Pooe, OJ; Kushwaha, ND; Mahlalela, M; van Zyl, RL; Gordon, M; Mudau, PT; Zininga, T; Shonhai, A; Nyamori, VO; Karpoormath, R or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

I found the field of Physiology; Respiratory System very interesting. Saw the article E-cigarettes and health risks: more to the flavor than just the name published in 2021.0. Name: 3,4-Dimethoxybenzaldehyde, Reprint Addresses Ween, MP (corresponding author), Royal Adelaide Hosp, Dept Thorac Med, Adelaide, SA, Australia.; Ween, MP (corresponding author), Univ Adelaide, Sch Med, Adelaide, SA, Australia.. The CAS is 120-14-9. Through research, I have a further understanding and discovery of 3,4-Dimethoxybenzaldehyde

The growing interest in regulating flavored E-liquids must incorporate understanding of the flavoring profile of each E-liquid-which flavorings (flavoring chemicals) are present and at what concentrations not just focusing on the flavor on the label. We investigated the flavoring profile of 10 different flavored E-liquids. We assessed bronchial epithelial cell viability and apoptosis, phagocytosis of bacteria and apoptotic cells by macrophages after exposure to E-cigarette vapor extract (EVE). We validated our data in normal human bronchial epithelial cells (NHBE) and alveolar macrophages (AM) from healthy donors. We also assessed cytokine release and validated in the saliva from E-cigarette users. Increased necrosis/apoptosis (16.1-64.5% apoptosis) in 16HBE cells was flavor dependent, and NHBEs showed an increased susceptibility to flavors. In THP-1 differentiated macrophages phagocytosis was also flavor dependent, with AM also showing increased susceptibility to flavors. Further, Banana and Chocolate were shown to reduce surface expression of phagocytic target recognition receptors on alveolar macrophages. Banana and Chocolate increased IL-8 secretion by NHBE, whereas all 4 flavors reduced AM IL-1 beta secretion, which was also reduced in the saliva of E-cigarette users compared with healthy controls. Flavorant profiles of E-liquids varied from simple 2 compound mixtures to complex mixtures containing over a dozen flavorants. E-liquids with high benzene content, complex flavoring profiles, high chemical concentration had the greatest impacts. The Flavorant profile of E-liquids is key to disruption of the airway status quo by increasing bronchial epithelial cell apoptosis, causing alveolar macrophage phagocytic dysfunction, and altering airway cytokines.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Ween, MP; Moshensky, A; Thredgold, L; Bastian, NA; Hamon, R; Badiei, A; Nguyen, PT; Herewane, K; Jersmann, H; Bojanowski, CM; Shin, J; Reynolds, PN; Alexander, LEC; Hodge, SJ or concate me.. Name: 3,4-Dimethoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Application In Synthesis of 3,4-Dimethoxybenzaldehyde. In 2021.0 MOL DIVERS published article about DERIVATIVES; FLAVONES; TUBULIN; DESIGN; ARREST in [Thorat, Nitin M.; Thopate, Shankar R.] Ahmednagar Coll, Prof John Barnabas Post Grad Sch Biol Studies, Dept Chem, Stn Rd, Ahmednagar 414001, Maharashtra, India; [Thorat, Nitin M.] Maharaja Jivajirao Shinde Arts Sci Commerce Coll, Dept Chem, Shrigonda 413701, Maharashtra, India; [Sarkate, Aniket P.] Dr Babasaheb Ambedkar Marathwada Univ, Dept Chem Technol, Aurangabad 431004, Maharashtra, India; [Lokwani, Deepak K.] RC Patel Inst Pharmaceut Educ & Res, Dept Pharmaceut Chem, Shirpur 425405, Maharashtra, India; [Tiwari, Shailee V.] Durgamata Inst Pharm, Dept Pharmaceut Chem, Parbhani 431401, Maharashtra, India; [Azad, Rajaram] Univ Hyderabad, Dept Anim Biol, Hyderabad 500046, India; [Thopate, Shankar R.] Shri Sadguru Gangageer Maharaj Sci Gautam Arts &, Dept Chem, Ahmednagar 423601, Maharashtra, India in 2021.0, Cited 31.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9.

Series of novel N-benzyl derivatives of 6-aminoflavone (9a-n) were synthesized and evaluated for anticancer and topoisomerase II enzyme inhibition activity. All the synthesized compounds were screened for in vitro anticancer activity against human breast cancer cell line (MCF-7) and human lung cancer cell line (A-549). Among the synthesized compounds, 9f and 9g were found to be the most potent anticancer agents against human breast cancer cell line (MCF-7) with IC50 values of 9.35 mu M and 9.58 mu M, respectively. Compounds 9b, 9c and 9n exhibited promising anticancer activity against human lung cancer cell line (A-549) with 43.71%, 46.48% and 44.26% inhibition at the highest concentration of 10 mu M, respectively. Compounds 9c, 9f and 9g have ability to inhibit the topoisomerase II enzyme. Compound 9f showed most potent topoisomerase II enzyme inhibition activity with IC50 value of 12.11 mu M. Further, these compounds have a high potential to be developed as a promising topoisomerase II inhibitors.

Application In Synthesis of 3,4-Dimethoxybenzaldehyde. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Thorat, NM; Sarkate, AP; Lokwani, DK; Tiwari, SV; Azad, R; Thopate, SR or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 120-14-9. Authors Mohamadpour, F in SPRINGER WIEN published article about in [Mohamadpour, Farzaneh] Apadana Inst Higher Educ, Sch Engn, Shiraz, Iran in 2021.0, Cited 32.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

Catalyst-free and solvent-free three-component tandem approach can synthesize 2-amino-4H-chromene scaffolds by Knoevenagel-Michael cyclocondensation of aryl aldehydes, malononitrile, and resorcinol via visible light irradiation as a green promoter at room temperature. The significant advantages of the present protocol include energy-effectiveness, catalyst-free, excellent yields, solvent-free, operational simplicity, and high atom-economy, commercially accessible inexpensive preliminary substances, so it meets some features of sustainable and green chemistry.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Mohamadpour, F or concate me.. SDS of cas: 120-14-9

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 120-14-9. Recently I am researching about HYDROGEN TRANSFER HYDROGENOLYSIS; N-DOPED CARBON; BIO-OIL; NONOXIDATIVE DEHYDROGENATION; ETHANOL DEHYDROGENATION; MECHANISTIC INSIGHTS; VERATRYL ALCOHOL; PD; AU; NANOPARTICLES, Saw an article supported by the National Key R&D Program of China [2017YFD0601003]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2019M662927]. Published in ELSEVIER in AMSTERDAM ,Authors: Zhang, HC; Liu, Y; Fu, SY; Deng, YL. The CAS is 120-14-9. Through research, I have a further understanding and discovery of 3,4-Dimethoxybenzaldehyde

Upgrading of lignin derived bio-oil is an essential step for producing sustainable bio-based chemicals and fuel. Taken into account that alpha hydroxyl is the abundant functional group in lignin, high effective and selective catalytic alcoholysis for cleaving the C-alpha-OH linkages would be desirable. However, an in-depth understanding of the reaction mechanisms involved in the cleavage of C-aromatic-C-alpha and C-alpha-O bonds over a novel catalyst is still needed. Herein, we report an efficient liquid-phase hydrogen transfer strategy for the selective hydrodeoxygenation of a non-phenolic lignin model compound, 3,4-dimethoxybenzyl (veratryl) alcohol, under mild conditions. By employing iso-propanol as solvent and H-donor, and palladium nanoparticles immobilized on nitrogen-doped carbon (Pd/CNX) as efficient multifunctional catalyst, veratryl alcohol dehydroxylation exhibited almost 100% conversion along with very high selectivity for 1,2-dimethoxy-benzene (46%) and 3,4-dimethoxytoluene (54%). Compared with other Pd catalysis, the Pd/CNX has excellent catalytic performances and exhibits higher selectivity for 3,4-dimethoxytoluene under incorporation with 1% HCOOH at 220 degrees C. The proportion of Pd (0) significantly increases in Pd/CNX catalyst when introduced into N precursor because of its highly dispersed Pd NPs and preventing the reoxidation of Pd (0). The dehydrogenation reaction occurred through the hydrogen generation of a secondary alcohol. Then, the C-alpha-OH and C-aromatic-C-alpha bonds of veratryl alcohol were selectively cleaved by catalytic transfer hydrogenolysis. The alcoholysis mechanism is supported by dispersion-corrected density functional theory computations. (C) 2020 Elsevier B.V. All rights reserved.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Zhang, HC; Liu, Y; Fu, SY; Deng, YL or concate me.. SDS of cas: 120-14-9

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Simple practical method for synthesis of trisubstituted imidazoles: an efficient copper catalyzed multicomponent reaction WOS:000667711300005 published article about LACTIM-LACTAM TAUTOMERISM; PHOTOPHYSICAL PROPERTIES; SUBSTITUTED IMIDAZOLES; SPECTROSCOPIC APPROACH; ANTIFUNGAL AGENTS; IONIC LIQUIDS; GREEN; OXIDATION; HYDROGEN; SYSTEM in [Kadu, Vikas D.; Mali, Ganesh A.; Khadul, Siddheshwar P.; Kothe, Gokul J.] Punyashlok Ahilyadevi Holkar Solapur Univ, Sch Chem Sci, Solapur 413255, Maharashtra, India in 2021.0, Cited 59.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9. Computed Properties of C9H10O3

A rapid practical process has been developed for synthesis of 2,4,5-trisubstituted-imidazoles in excellent yields up to 95% from readily available starting materials. In this CuI catalyzed synthesis, trisubstituted imidazoles were afforded in short reaction times, wherein the substrate scope is well explored with benzoin as well as benzil reacting with different aldehydes in the presence of ammonium acetate as the nitrogen source.

Computed Properties of C9H10O3. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Kadu, VD; Mali, GA; Khadul, SP; Kothe, GJ or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Safety of 3,4-Dimethoxybenzaldehyde. I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article 3,7-bis-benzylidene hydrazide ciprofloxacin derivatives as promising antiproliferative dual TOP I & TOP II isomerases inhibitors published in 2021, Reprint Addresses Abdel-Aziz, M (corresponding author), Menia Univ, Fac Pharm, Dept Med Chem, Al Minya 61519, Egypt.; Abuo-Rahma, GEDA (corresponding author), Deraya Univ, Fac Pharm, Dept Pharmaceut Chem, New Minia, Minia, Egypt.. The CAS is 120-14-9. Through research, I have a further understanding and discovery of 3,4-Dimethoxybenzaldehyde.

We report herein design and synthesis of a new series of 3,7-bis-benzylidenes of ciprofloxacin. Most of the target compounds revealed good cytotoxic activity; the most potent 4e and 4i achieved strong broad spectrum antiproliferative activity with comparable activity to Doxorubicin with IC50 (M-mu) of 1.21 +/- 0.02, 0.87 +/- 0.04, 1.21 +/- 0.02; 0.41 +/- 0.02, 0.57 +/- 0.06, 1.31 +/- 0.04 and 1.26 +/- 0.01, 1.79 +/- 0.04, 0.63 +/- 0.01 against leukemia cancer cell line HL-60 (TB), colon cancer cell line HCT-116 and breast cancer cell line MCF7, respectively. Moreover, the most potent derivative 4i induced apoptosis at G2/M phase Investigating the mechanism of action of compounds 4e, 4 h and 4i exhibited promising dual TOP I alpha and TOP IIB % inhibition comparable to Camptothecin and Etoposide; respectively. Docking of 4e, 4 h and 4i into the active site of topo I and II proteins compared to Camptothein and Etoposide revealed acceptable binding score and augmented enzyme assay data. Hence, 4e and 4i are promising targeted antiproliferative dual acting TOP I alpha TOP IIB inhibitors that require further optimization.

Safety of 3,4-Dimethoxybenzaldehyde. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Samir, M; Ramadan, M; Abdelrahman, MH; Abdelbaset, MS; Abourehab, MAS; Abdel-Aziz, M; Abuo-Rahma, GEDA or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Product Details of 120-14-9. Authors Chu, PC; Wu, YC; Chen, CY; Hung, YS; Chang, CS in FUTURE SCI LTD published article about in [Chu, Po-Chen] China Med Univ, Dept Cosmeceut, Taichung 40402, Taiwan; [Chu, Po-Chen] China Med Univ, Grad Inst Cosmeceut, Taichung 40402, Taiwan; [Chu, Po-Chen; Chang, Chih-Shiang] China Med Univ, Drug Dev Ctr, Taichung 40402, Taiwan; [Wu, Yu-Chieh; Chen, Chien-Yu; Hung, Yu-Syuan; Chang, Chih-Shiang] China Med Univ, Sch Pharm, Coll Pharm, Taichung 40402, Taiwan in 2021, Cited 35. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

Aim: Tumor cells adapt to hypoxic microenvironments by releasing the key transcription factor HIF-1 alpha, which promotes angiogenesis, glycolytic phenotype, metastasis and erythropoiesis, allowing proliferation amid low oxygen levels. Therefore, therapeutic targeting of HIF-1 alpha represents a viable strategy for cancer therapy. Methods & Results: The authors synthesized a series of novel tetrahydroquinazoline derivatives in six steps and demonstrated that their development had a unique ability to suppress HIF-1 alpha expression through proteasomal degradation. Conclusion: Among these compounds, CDMP-TQZ (8bf) exhibited the highest antiproliferative potency in human cancer cells, in part through downregulation of HIF-1 alpha.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Chu, PC; Wu, YC; Chen, CY; Hung, YS; Chang, CS or concate me.. Product Details of 120-14-9

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Direct Access for the Regio- and Stereoselective Synthesis of N-Alkenylpyrazoles and Chromenopyrazoles WOS:000618540600019 published article about ONE-POT SYNTHESIS; REGIOSELECTIVE SYNTHESIS; FACILE SYNTHESIS; PYRAZOLES; HYDRAZONES; ALKYNES; TOSYLHYDRAZONES; DERIVATIVES; HYDRAZIDES; COMPLEXES in [Kurma, Siva Hariprasad; Bhimapaka, China Raju] CSIR Indian Inst Chem Technol, Dept Organ Synth & Proc Chem, Hyderabad 500007, India; [Kurma, Siva Hariprasad; Bhimapaka, China Raju] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India; [Sridhar, Balasubramanian] CSIR Indian Inst Chem Technol, Dept Analyt & Struct Chem, Hyderabad 500007, India in 2021.0, Cited 61.0. SDS of cas: 120-14-9. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

A highly regio- and stereoselective method was developed for the preparation of N-alkenylpyrazoles and chromenopyrazoles by the reaction of N-tosylhydrazones and salicyl N-tosylhydrazones with alkynes under neat conditions in the presence of La(OTf)(3). The present study was found to be efficient and convenient for direct access to N-alkenylpyrazoles and chromenopyrazoles through C-C, C-N, and C-O bond forming reactions. Structure assignment of N-alkenylpyrazole compound 5c was confirmed by X-ray analysis.

SDS of cas: 120-14-9. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Kurma, SH; Sridhar, B; Bhimapaka, CR or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article A novel method of temporary solidification and extraction of underwater fragile relics in their original state WOS:000589895000001 published article about IN-SITU PRESERVATION; CULTURAL-HERITAGE; CONSOLIDANT; CONSERVATION; MENTHOL in [Chen, Xue-Qiang; Zhang, Bingjian] Zhejiang Univ, Dept Cultural Heritage & Museol, Hangzhou 310028, Peoples R China; [Chen, Xue-Qiang] Ningbo Univ Finance & Econ, Cultural Property Protect Ctr, Ningbo 315175, Peoples R China; [Zhang, Zhiguo] Natl Ctr Underwater Cultural Heritage, Beijing 100192, Peoples R China in 2021.0, Cited 22.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9. COA of Formula: C9H10O3

Fragile cultural relics at underwater archaeological sites are difficult to preserve in situ over long time periods due to the effects of a complex and constantly changing surrounding environment. Thus, extracting the relics from water and preserving them in a controllable environment is of primary importance. In this paper, the technology of temporary reinforcement and extraction of underwater fragile relics with veratraldehyde followed by a process of secondary temporary reinforcement using polyethylene glycol (PEG) was studied. After investigating the melting temperature and permeability of PEGs with different molecular weights, we found that PEG-3000 is an excellent candidate as the secondary reinforcing agent for the extracted relics. In the laboratory, combined with veratraldehyde and polypropylene-fiber cloth as temporary underwater strengthening materials, and selected dispersed beaded jewelry and a broken three-dimensional crock as our research subject, we carried out an entire retrieval process-temporary stabilization and secondary temporary reinforcement, to systematically evaluate the technological aspects of safely excavating fragile underwater relics in the original state. After being extracted from water and subjected to secondary temporary reinforcement using PEG-3000, the beaded jewelry and broken crock retained their underwater shape and arrangement completely. The use of secondary reinforcing agent prevents the removal process of veratraldehyde and enclosed sediment from affecting the state of the relics.

COA of Formula: C9H10O3. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Chen, XQ; Zhang, BJ; Zhang, ZG or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles