Category: 120-14-9

An article Structure-activity relationship and biological evaluation of berberine derivatives as PCSK9 down-regulating agents WOS:000663790900001 published article about HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA; HIGH CARDIOVASCULAR RISK; LDL; DEGRADATION; INHIBITION; EVOLOCUMAB; EXPRESSION; EFFICACY; THERAPY; SAFETY in [Fan, Tian-Yun; Yang, Yu-Xin; Zeng, Qing-Xuan; Wang, Xue-Lei; Wei, Wei; Guo, Xi-Xi; Zhao, Li-Ping; Song, Dan-Qing; Wang, Yan-Xiang; Wang, Li; Hong, Bin] Chinese Acad Med Sci & Peking Union Med Coll, Inst Med Biotechnol, Beijing 10050, Peoples R China in 2021, Cited 31. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9. SDS of cas: 120-14-9

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a secreted protein and its deficiency markedly enhanced the survival rate of patient with cardiovascular diseases (CVDs). Forty berberine (BBR) derivatives were synthesized and evaluated for their activities on down-regulating the transcription of PCSK9 in HepG2 cells, taking BBR as the lead. Structure-activity relationship (SAR) analysis revealed that 2,3-dimethoxy moiety might be beneficial for activity. Among them, 9k displayed the most potent activity with IC50 value of 9.5 +/- 0.5 mu M, better than that of BBR. Also, it significantly decreased PCSK9 protein level at cellular level, as well as in the liver and serum of mice in vivo. Furthermore, 9k markedly increased LDLR expression and LDL-C clearance via downregulating PCSK9 protein. The mechanism of action of 9k is targeting HNF1 alpha and/or Sp1 cluster modulation upstream of PCSK9, a different one from BBR. Therefore, 9k might have the potential to be a novel PCSK9 transcriptional inhibitor for the treatment of atherosclerosis, worthy for further investigation.

SDS of cas: 120-14-9. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Fan, TY; Yang, YX; Zeng, QX; Wang, XL; Wei, W; Guo, XX; Zhao, LP; Song, DQ; Wang, YX; Wang, L; Hong, B or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about MULTICOMPONENT SYNTHESIS; DERIVATIVES; EFFICIENT; CATALYST; MILD, Saw an article supported by the . Published in ELSEVIER in AMSTERDAM ,Authors: Tabassum, S; Devi, KRS; Govindaraju, S. The CAS is 120-14-9. Through research, I have a further understanding and discovery of 3,4-Dimethoxybenzaldehyde. Safety of 3,4-Dimethoxybenzaldehyde

The investigation presents a straightforward synthesis of fifteen 1,4-dihydropyrano[2,3-c]pyrazoles using ZnO@PEG nanocatalyst in ethanol via Multicomponent approach under the influence of ultrasound. The present methodology successively tolerates a variety of functional groups and offers several advantages such as excellent yields without chromatographic purification, milder reaction conditions, shorter reaction times, and the use of an environmentally benign reusable catalyst. Ecstatically, the reaction was successfully scaled to gram level ascertaining the wider applicability of ZnO@PEG nanoparticles in multicomponent reactions. (C) 2019 Elsevier Ltd. All rights reserved.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Tabassum, S; Devi, KRS; Govindaraju, S or concate me.. Safety of 3,4-Dimethoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Kayamba, F; Malimabe, T; Ademola, IK; Pooe, OJ; Kushwaha, ND; Mahlalela, M; van Zyl, RL; Gordon, M; Mudau, PT; Zininga, T; Shonhai, A; Nyamori, VO; Karpoormath, R in ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER published article about MOLECULAR-DYNAMICS; ASSAY in [Kayamba, Francis; Kushwaha, Narva Deshwar; Mahlalela, Mavela; Karpoormath, Rajshekhar] Univ KwaZulu Natal, Coll Hlth Sci, Dept Pharmaceut Chem, ZA-4000 Durban, South Africa; [Malimabe, Teboho; van Zyl, Robyn L.] Univ Witwatersrand, Fac Hlth Sci, Dept Pharm & Pharmacol, Pharmacol Div, ZA-2193 Johannesburg, South Africa; [Malimabe, Teboho; van Zyl, Robyn L.] Univ Witwatersrand, Fac Hlth Sci, WITS Res Inst Malaria WRIM, ZA-2193 Johannesburg, South Africa; [Ademola, Idowu Kehinde; Gordon, Michelle] Univ KwaZulu Natal, Coll Hlth Sci, Sch Lab Med & Med Sci, ZA-4000 Durban, South Africa; [Pooe, Ofentse Jacob] Univ KwaZulu Natal, Sch Life Sci, Discipline Biochem, ZA-4000 Durban, South Africa; [Mudau, Pertunia T.; Zininga, Tawanda] Univ Venda, Sch Math & Nat Sci, Dept Biochem, ZA-0950 Thohoyandou, South Africa; [Zininga, Tawanda; Shonhai, Addmore] Stellenbosch Univ, Dept Biochem, ZA-7600 Stellenbosch, South Africa; [Nyamori, Vincent O.] Univ KwaZulu Natal, Sch Chem & Phys, Westville Campus, ZA-4000 Durban, South Africa in 2021, Cited 43. Quality Control of 3,4-Dimethoxybenzaldehyde. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

Presently, artemisinin-based combination therapy (ACT) is the first-line therapy of Plasmodium falciparum malaria. With the emergence of malaria parasites that are resistant to ACT, alternative antimalarial therapies are urgently needed. In line with this, we designed and synthesised a series of novel N-(7chloroquinolin-4-yl)-N’-(4,6-diphenylpyrimidin-2-yl)alkanediamine hybrids (6a-7c) and evaluated their inhibitory activity against the NF54 chloroquine-susceptible strain as a promising class of antimalarial compounds. The antiplasmodial screening revealed that seven analogues showed promising to good activity with half-maximal inhibitory concentration ( IC50) = 0.32 mu Me4.30 mM. Compound 7a with 1,4-diamine butyl linker and 4-hydroxyl phenyl on fourth and sixth position of pyrimidine core showed the most prominent activity with an IC50 value of 0.32 +/- 0.06 mM, with a favourable safety profile of 9.79 to human kidney epithelial (HEK293) cells. The remaining six analogues showed moderate activity with IC50 values ranging from 7.50 mM to 83.01 mM. We further investigated the binding affinities of the molecules to two essential cytosolic P. falciparum heat shock protein 70 homologues; PfHsp70-1 and PfHsp70-z. Compound 7a exhibited the highest binding affinity for both PfHsp70s with K-D in a lower nanomolar range (4.4-11.4 nM). Furthermore, molecular docking revealed that compounds 6, 6k, 7b and 7a exhibited better fitness in PfHsp70-1 with compound 7a showing the highest and lowest binding scores of similar to 9.8 kcal/mol. Therefore, we speculate that PfHsp70-1 is one of the targets of these inhibitors. The bioisoteric replacement of the groups at phenyl ring at the fourth and sixth position of the pyrimidine core had a constructive association with antiplasmodial activity. The promising antiplasmodial activity of the synthesised analogues illustrates how crucial molecular hybridisation is as a strategy in the development of quinoline-pyrimidine hybrids as prospective antiprotozoal agents. (C) 2021 Elsevier Masson SAS. All rights reserved.

Quality Control of 3,4-Dimethoxybenzaldehyde. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Kayamba, F; Malimabe, T; Ademola, IK; Pooe, OJ; Kushwaha, ND; Mahlalela, M; van Zyl, RL; Gordon, M; Mudau, PT; Zininga, T; Shonhai, A; Nyamori, VO; Karpoormath, R or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In 2021.0 EUR J ORG CHEM published article about ALCOHOLS; FLUORINE; OXALATES in [Zemtsov, Artem A.; Lunkov, Sergey S.; Levin, Vitalij V.; Dilman, Alexander D.] ND Zelinskii Inst Organ Chem, Leninsky Prosp 47, Moscow 119991, Russia; [Lunkov, Sergey S.] Moscow MV Lomonosov State Univ, Dept Chem, Leninskie Gory 1-3, Moscow 119991, Russia in 2021.0, Cited 39.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9. SDS of cas: 120-14-9

A method for the synthesis of trifluoromethyl-substituted dithiocarbamates from aldehydes is described. The reaction involves nucleophilic trifluoromethylation, derivatization of the silyloxy-group with pentafluoropyridine, and substitution of the fluorinated pyridinyloxy group by dithiocarbamate anion. The substitution step is performed in the presence of 12-phenyl-12H-benzo[b]phenothiazine and copper cyanide under irradiation of 400 nm LED.

SDS of cas: 120-14-9. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Zemtsov, AA; Lunkov, SS; Levin, VV; Dilman, AD or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: 120-14-9. Authors Kumari, M; Tahlan, S; Narasimhan, B; Ramasamy, K; Lim, SM; Shah, SAA; Mani, V; Kakkar, S in BMC published article about in [Kumari, Mukesh; Tahlan, Sumit; Narasimhan, Balasubramanian; Kakkar, Saloni] Maharshi Dayanand Univ, Fac Pharmaceut Sci, Rohtak 124001, Haryana, India; [Ramasamy, Kalavathy; Lim, Siong Meng; Shah, Syed Adnan Ali] Univ Teknol MARA UiTM, Fac Pharm, Bandar Puncak Alam 42300, Selangor Darul, Malaysia; [Ramasamy, Kalavathy; Lim, Siong Meng] Univ Teknol MARA UiTM, Collaborat Drug Discovery Res CDDR Grp, Pharmaceut Life Sci Community Res, Shah Alam 40450, Selangor Darul, Malaysia; [Shah, Syed Adnan Ali] Univ Teknol MARA UiTM, Atta Ur Rahman Inst Nat Prod Discovery AuRIns, Puncak Alam Campus, Bandar Puncak Alam 42300, Selangor Darul, Malaysia; [Mani, Vasudevan] Qassim Univ, Dept Pharmacol & Toxicol, Coll Pharm, Buraydah 51452, Saudi Arabia in 2021.0, Cited 27.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

Background Triazole is an important heterocyclic moiety that occupies a unique position in heterocyclic chemistry, due to its large number of biological activities. It exists in two isomeric forms i.e. 1,2,4-triazole and 1,2,3-triazole and is used as core molecule for the design and synthesis of many medicinal compounds. 1,2,4-Triazole possess broad spectrum of therapeutically interesting drug candidates such as analgesic, antiseptic, antimicrobial, antioxidant, anti-urease, anti-inflammatory, diuretics, anticancer, anticonvulsant, antidiabetic and antimigraine agents. Methods The structures of all synthesized compounds were characterized by physicochemical properties and spectral means (IR and NMR). The synthesized compounds were evaluated for their in vitro antimicrobial activity against Gram-positive (B. subtilis), Gram-negative (P. aeruginosa and E. coli) bacterial and fungal (C. albicans and A. niger) strains by tube dilution method using ciprofloxacin, amoxicillin and fluconazole as standards. In-vitro antioxidant and anti-urease screening was done by DPPH assay and indophenol method, respectively. The in-vitro anticancer evaluation was carried out against MCF-7 and HCT116 cancer cell lines using 5-FU as standards. Results, discussion and conclusion The biological screening results reveal that the compounds T-5 (MICBS, EC = 24.7 mu M, MICPA, (CA) = 12.3 mu M) and T-17 (MICAN = 27.1 mu M) exhibited potent antimicrobial activity as comparable to standards ciprofloxacin, amoxicillin (MICCipro = 18.1 mu M, MICAmo = 17.1 mu M) and fluconazole (MICFlu = 20.4 mu M), respectively. The antioxidant evaluation showed that compounds T-2 (IC50 = 34.83 mu g/ml) and T-3 (IC50 = 34.38 mu g/ml) showed significant antioxidant activity and comparable to ascorbic acid (IC50 = 35.44 mu g/ml). Compounds T-3 (IC50 = 54.01 mu g/ml) was the most potent urease inhibitor amongst the synthesized compounds and compared to standard thiourea (IC50 = 54.25 mu g/ml). The most potent anticancer activity was shown by compounds T-2 (IC50 = 3.84 mu M) and T-7 (IC50 = 3.25 mu M) against HCT116 cell lines as compared to standard 5-FU (IC50 = 25.36 mu M).

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Kumari, M; Tahlan, S; Narasimhan, B; Ramasamy, K; Lim, SM; Shah, SAA; Mani, V; Kakkar, S or concate me.. Recommanded Product: 120-14-9

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 120-14-9. In 2021 RSC ADV published article about ONE-POT; MAGNETIC NANOPARTICLES; CLAISEN REARRANGEMENT; DERIVATIVES; EFFICIENT; GLYCALS; DRUGS; DECONTAMINATION; HETEROCYCLES; ANTICANCER in [Torabi, Morteza; Yarie, Meysam; Zolfigol, Mohammad Ali] Buali Sina Univ, Fac Chem, Dept Organ Chem, Hamadan 6517838683, Hamadan, Iran; [Rouhani, Shamila; Msagati, Titus A. M.] Univ South Africa, Coll Sci Engn & Technol, Inst Nanotechnol & Water Sustainabil iNanoWS, ZA-1709 Johannesburg, South Africa; [Azizi, Shohreh; Maaza, Malik] Univ South Africa, Coll Grad Studies, UNESCO UNISA Africa Chair Nanosci & Nanotech, POB 392, Pretoria, South Africa; [Azizi, Shohreh] iThemba LABS Natl Res Fdn, Nanosci African Network NANOAFNET, 1 Old Faure Rd,POB 722, ZA-7129 Western Cape, South Africa; [Olomola, Temitope O.] Obafemi Awolowo Univ, Dept Chem, Ife 220005, Nigeria; [Msagati, Titus A. M.] Nelson Mandela African Inst Sci & Technol, Sch Life Sci & Bioengn, POB 447, Arusha, Tanzania in 2021, Cited 96. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9.

In the present study, we reported the synthesis of a novel quinoline-based dendrimer-like ionic liquid. After characterization of the mentioned ionic liquid with suitable techniques such as Fourier transform infrared spectroscopy (FT-IR), energy dispersive X-ray spectroscopy (EDX), elemental mapping, thermogravimetric analysis (TGA) and derivative thermogravimetry (DTG), its catalytic performance was investigated in the synthesis of new pyridines with sulfonamide moiety via a cooperative vinylogous anomeric-based oxidation mechanism under mild reaction conditions. All target molecules were achieved in short reaction times and high yields.

SDS of cas: 120-14-9. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Torabi, M; Yarie, M; Zolfigol, MA; Rouhani, S; Azizi, S; Olomola, TO; Maaza, M; Msagati, TAM or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Quality Control of 3,4-Dimethoxybenzaldehyde. I found the field of Chemistry very interesting. Saw the article BCl3 Catalyzed, Solvent Free Protocol for the Synthesis of Dihydropyrano[3,2-b] Chromenediones published in 2021, Reprint Addresses Mathapati, SR (corresponding author), Shri Madhavrao Patil Mahavidyalaya, Dept Chem, Murum 413605, India.; Mathapati, SR (corresponding author), Dr BAM Univ, Aurangabad, Maharashtra, India.. The CAS is 120-14-9. Through research, I have a further understanding and discovery of 3,4-Dimethoxybenzaldehyde.

Solvent free synthesis of dihydropyrano[3,2-b]chromenediones was formulated via multicomponent reactions of kojic acid, dimedone and several substituted aromatic aldehydes catalyzed with BCl3. Reactions progressed efficiently and the corresponding heterocyclic products were obtained in good to high yields within short period. The developed protocol is one of the better and efficient alternative methods for the synthesis of dihydropyrano[3,2-b]chromenediones. The simple reaction procedure, easy separation of products, radially available catalyst are certain benefits of this reported protocol.

Quality Control of 3,4-Dimethoxybenzaldehyde. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Suryawanshi, VB; Momin, KI; Dawle, JK; Mathapati, SR or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: C9H10O3. Recently I am researching about SOLVENT-FREE; CHEMOSELECTIVE ACETALIZATION; EFFICIENT CATALYST; HIGHLY EFFICIENT; ACID CATALYSTS; ALDEHYDES; ACETALS; MILD; KETALIZATION, Saw an article supported by the Science and Technology Commission of Shanghai MunicipalityScience & Technology Commission of Shanghai Municipality (STCSM) [14DZ1900102]; Fundamental Research Funds for the Central University [WY1113007]. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Wang, D; Cao, FR; Lu, GY; Ren, JM; Zeng, BB. The CAS is 120-14-9. Through research, I have a further understanding and discovery of 3,4-Dimethoxybenzaldehyde

A novel PVP-I catalyzed acetalizations/transacetalizations of carbonyl compounds has been developed processing with a mild and easy handling fashion. Different types of Acyclic and cyclic acetals were prepared from carbonyl compounds or their acetals successfully. Further applications of newly developed catalytic combination were testified. This protocol featured with simplicity of operation, mild reaction condition, short reaction time, recyclable of catalyst and broad substrates scope with excellent yields. (c) 2021 Elsevier Ltd. All rights reserved.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Wang, D; Cao, FR; Lu, GY; Ren, JM; Zeng, BB or concate me.. HPLC of Formula: C9H10O3

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 120-14-9. Authors Tan, E; Nannini, LJ; Stoica, O; Echavarren, AM in AMER CHEMICAL SOC published article about in [Tan, Eric; Nannini, Leonardo J.; Stoica, Otilia; Echavarren, Antonio M.] Inst Chem Res Catalonia ICIQ, Tarragona 43007, Spain; [Stoica, Otilia] Univ Rovira & Virgili, Dept Quim Analit & Quim Organ, Tarragona 43007, Spain in 2021.0, Cited 87.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

The Rh(III)-catalyzed ortho-alkynylation of benzaldehydes is enabled by the transient formation of an imine as a directing group. A broad scope of substrates was obtained under mild reaction conditions, granting access to mono- and dialkynylated products. The functionalization of readily available building blocks allowed the development of modular syntheses of dibenzopentalenes, isoquinolines, indoles, and indolines.

SDS of cas: 120-14-9. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Tan, E; Nannini, LJ; Stoica, O; Echavarren, AM or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

I found the field of Chemistry very interesting. Saw the article Synthesis, structure, characterization and biological evaluation of 3-substituted 1-pyridin-2-ylimidazo[1,5-a]pyridine-based copper(I)-phosphine complexes for anticancer drug screening published in 2021. COA of Formula: C9H10O3, Reprint Addresses Velusamy, M (corresponding author), North Eastern Hill Univ, Dept Chem, Shillong 793022, Meghalaya, India.; Murali, M (corresponding author), Natl Coll Autonomous, Dept Chem, Coordinat & Bioinorgan Chem Res Lab, Tiruchirappalli 620001, Tamil Nadu, India.. The CAS is 120-14-9. Through research, I have a further understanding and discovery of 3,4-Dimethoxybenzaldehyde

Copper(I) complexes of the types [Cu(N-N)(PPh3)(2)]NO3(LC41-LC44) and [Cu(N-N)(PPh3)(NO3)] (LC45) carrying 3-substituted 1-pyridine-2-ylimidazo[1,5-a]pyridine (N-N) derivatives and triphenylphosphine (PPh3) ligands have been prepared. The synthesized copper(I)-phosphine complexes were fully characterized by NMR, IR, ESI-MS and UV-visible spectroscopy as well as by cyclic voltammetry. Selected structures such as LC42, LC43 and LC45 were additionally analysed by single-crystal X-ray method, which show that copper(I) centre adopts a highly distorted tetrahedral geometry. The(1)H and(13)C NMR spectral data of the complexes throw light on the nature of metal-ligand bonding. They display d pi-pi* metal-to-ligand charge transfer (MLCT) transition and show quasireversible Cu-I/Cu(II)metal oxidation. Among the copper(I)-phosphine complexes, LC41-LC44 exhibit moderate cytotoxicity (IC50: 24 h, 67-74 mu M; 48 h, 58-70 mu M) against human lung epithelial adenocarcinoma A549 cells, whereas LC45 displays the best activity (IC50: 24 h, 42 mu M; 48 h, 34 mu M) for A549 cancer cell line, which is better than that of the commercial antitumor drug cisplatin. All the complexes also displayed excellent selectivity by being relatively inactive against the human lung epithelial L132 normal cell line with selectivity index (SI) values ranging from 3.4 to 7.4. The complexes block cell cycle progression of A549 cells in G(0)/G(1)phase. FACSVerse analyses are suggestive of reactive oxygen species (ROS) generation and apoptotic cell death induced by the LC41, LC43 and LC45. The induction of apoptosis in A549 cells was shown by Annexin V with propidium iodide (PI) and 4 ‘,6-diamidino-2-phenylindole (DAPI) staining methods and established the ability of LC41, LC43 and LC45 to accumulate in the cell nuclei.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Pathaw, L; Khamrang, T; Selvakumaran, B; Murali, M; Prakash, PA; Jaabir, MSM; Velusamy, M or concate me.. COA of Formula: C9H10O3

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles