Category: 120-14-9

Category: indole-building-block. In 2021.0 ANGEW CHEM INT EDIT published article about CONJUGATED DIENES; ENANTIOSELECTIVE 1,2-DIFUNCTIONALIZATION; INTERMOLECULAR 1,2-DIAMINATION; REGIOSELECTIVE DIAMINATION; PALLADIUM; ALKENES; OLEFINS; ALKYL; ISOTHIOCYANATES; CHEMISTRY in [Guo, Weisi; Wang, Qian; Zhu, Jieping] Ecole Polytech Fed Lausanne, Inst Chem Sci & Engn, Lab Synth & Nat Prod, EPFL,SB,ISIC,LSPN, BCH 5304, CH-1015 Lausanne, Switzerland; [Guo, Weisi] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, 53 Zhengzhou Rd, Qingdao, Peoples R China in 2021.0, Cited 86.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9.

Selective three-component 1,2-diamination of 1,3-dienes with concurrent introduction of two orthogonally protected amino groups remains unknown despite its significant synthetic potential. We report herein that reaction of conjugated dienes with N-aminopyridinium salts and TMSNCS affords 1,2-aminoisothiocyanation products in a highly chemo- and regio-selective manner under mild photoredox catalytic conditions. Mechanistic studies indicate that the facile isomerization of allyl thiocyanates to allyl isothiocyanates under photocatalytic conditions is responsible for the selective formation of the observed products. The mild isomerization protocol is expected to find applications in the synthesis of allyl isothiocyanates in a broad sense.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Guo, WS; Wang, Q; Zhu, JP or concate me.. Category: indole-building-block

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Direct Access for the Regio- and Stereoselective Synthesis of N-Alkenylpyrazoles and Chromenopyrazoles WOS:000618540600019 published article about ONE-POT SYNTHESIS; REGIOSELECTIVE SYNTHESIS; FACILE SYNTHESIS; PYRAZOLES; HYDRAZONES; ALKYNES; TOSYLHYDRAZONES; DERIVATIVES; HYDRAZIDES; COMPLEXES in [Kurma, Siva Hariprasad; Bhimapaka, China Raju] CSIR Indian Inst Chem Technol, Dept Organ Synth & Proc Chem, Hyderabad 500007, India; [Kurma, Siva Hariprasad; Bhimapaka, China Raju] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India; [Sridhar, Balasubramanian] CSIR Indian Inst Chem Technol, Dept Analyt & Struct Chem, Hyderabad 500007, India in 2021.0, Cited 61.0. Computed Properties of C9H10O3. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

A highly regio- and stereoselective method was developed for the preparation of N-alkenylpyrazoles and chromenopyrazoles by the reaction of N-tosylhydrazones and salicyl N-tosylhydrazones with alkynes under neat conditions in the presence of La(OTf)(3). The present study was found to be efficient and convenient for direct access to N-alkenylpyrazoles and chromenopyrazoles through C-C, C-N, and C-O bond forming reactions. Structure assignment of N-alkenylpyrazole compound 5c was confirmed by X-ray analysis.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Kurma, SH; Sridhar, B; Bhimapaka, CR or concate me.. Computed Properties of C9H10O3

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

COA of Formula: C9H10O3. Authors Reihani, N; Kiyani, H in BENTHAM SCIENCE PUBL LTD published article about in [Reihani, Neda; Kiyani, Hamzeh] Damghan Univ, Sch Chem, POB 36716-41167, Damghan, Iran; [Kiyani, Hamzeh] Shahrekord Univ, Fac Sci, Dept Chem, Shahrekord, Iran in 2021.0, Cited 67.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

An efficient synthesis of 4-arylidene-3-alkylisoxazole-5(4H)-ones has been implemented via the three-component cyclocondensation of aryl(heteroaryl)aldehydes with hydroxylamine hydrochloride and beta-ketoesters. The potassium 2,5-dioxoimidazolidin-1-ide has been introduced as the new organocatalyst to facilitate this heterocyclization. In the current process, three starting materials, including substituted benzaldehydes/heterocyclic aromatic aldehydes, hydroxylamine hydrochloride, and ethyl acetoacetate/propyl acetoacetate/butyryl acetoacetate have been successfully used to synthesize the number of substituted isoxazole-5-(4H)-ones in good to high yields in ethylene glycol as a green reaction medium at 80 degrees C. The low catalyst loading is also a main advantage over some reported catalysts.

COA of Formula: C9H10O3. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Reihani, N; Kiyani, H or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article An insight into the superior performance of ZnO@PEG nanocatalyst for the synthesis of 1,4-dihydropyrano[2,3-c]pyrazoles under ultrasound WOS:000655645000014 published article about MULTICOMPONENT SYNTHESIS; DERIVATIVES; EFFICIENT; CATALYST; MILD in [Tabassum, Sumaiya] Surana Coll, Dept Chem, South End Rd, Basavanagudi 560004, Bengaluru, India; [Devi, Sunaja K. R.] CHRIST Deemed Univ, Dept Chem, Bengaluru 560029, India; [Govindaraju, Santhosh] CHRIST Deemed Univ, Sch Engn & Technol, Dept Sci & Humanities, Mysore Rd, Bengaluru 560074, India in 2021.0, Cited 23.0. Application In Synthesis of 3,4-Dimethoxybenzaldehyde. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

The investigation presents a straightforward synthesis of fifteen 1,4-dihydropyrano[2,3-c]pyrazoles using ZnO@PEG nanocatalyst in ethanol via Multicomponent approach under the influence of ultrasound. The present methodology successively tolerates a variety of functional groups and offers several advantages such as excellent yields without chromatographic purification, milder reaction conditions, shorter reaction times, and the use of an environmentally benign reusable catalyst. Ecstatically, the reaction was successfully scaled to gram level ascertaining the wider applicability of ZnO@PEG nanoparticles in multicomponent reactions. (C) 2019 Elsevier Ltd. All rights reserved.

Application In Synthesis of 3,4-Dimethoxybenzaldehyde. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Tabassum, S; Devi, KRS; Govindaraju, S or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Triethylammonium Hydrogen Sulfate [Et3NH][HSO4]-Catalyzed Rapid and Efficient Multicomponent Synthesis of Pyrido[2,3-d]pyrimidine and Pyrazolo[3,4-b]pyridine Hybrids WOS:000677481800042 published article about ONE-POT SYNTHESIS; IONIC LIQUIDS; PYRAZOLE DERIVATIVES; TEMPERATURE; SOLVENTS; DESIGN; AGENTS; ACID in [Jadhav, Chetan; Nipate, Amol; Chate, Asha; Gill, Charansingh] Dr Babasaheb Ambedkar Marathwada Univ, Dept Chem, Aurangabad 431004, Maharashtra, India in 2021.0, Cited 55.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9. Quality Control of 3,4-Dimethoxybenzaldehyde

An operationally simple, one-pot multicomponent reaction has been developed for the assembly of pyrido[2,3-d]pyrimidine and pyrazolo[3,4-b]pyridine derivatives (4a-4am) in excellent yields (92-94%) with high purity. The reactions were easy to perform simply by mixing of electron-rich amino heterocycles (including aminouracils and aminopyrazoles), aldehyde, and acyl acetonitrile in the presence of [Et3NH][HSO4] under solvent-free conditions. The remarkable feature of the present approach is that the ionic liquid possesses dual solvent-catalytic engineering capability. Results of this study revealed that 1 mmol of the ionic liquid catalyst under solvent-free conditions at 60 degrees C is the best reaction parameter for the construction of fused pyridine and pyrimidine derivatives in excellent yields. The present methodology showed good results under gram-scale conditions, thereby indicating its applicability in industrial as well as academic settings in the near future.

Quality Control of 3,4-Dimethoxybenzaldehyde. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Jadhav, C; Nipate, A; Chate, A; Gill, C or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Synthesis and Characterization of Magnetic Functionalized Ni and Cu Nano Catalysts and Their Application in Oxidation, Oxidative Coupling and Various Multi-Component Reactions WOS:000604191500004 published article about ONE-POT SYNTHESIS; RECYCLABLE CATALYST; EFFICIENT CATALYST; 5-SUBSTITUTED 1H-TETRAZOLES; SELECTIVE OXIDATION; HYDROGEN-PEROXIDE; IRON-OXIDE; NANOPARTICLES; SULFIDES; COMPLEX in [Hajjami, Maryam] Bu Ali Sina Univ, Dept Organ Chem, Fac Chem, Hamadan 6517838683, Hamadan, Iran; [Sheikhaei, Shiva; Gholamian, Fatemeh; Yousofvand, Zakieh] Ilam Univ, Fac Sci, Dept Chem, POB 69315516, Ilam, Iran in 2021.0, Cited 47.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9. SDS of cas: 120-14-9

Two magnetic nano catalysts of nickel and copper, Fe3O4@SiO2@DOP-BenPyr-M(II), (M=Ni and Cu) have been synthesized. These catalysts were applied as recoverable, efficient and new heterogeneous catalysts for the high yielding and room temperature one-pot procedure of selective oxidation of sulfides to sulfoxides and oxidative coupling of thiols to disulfides. In addition, the catalytic activity of Fe3O4@SiO2@DOP-BenPyr-Ni(II) was investigated as heterogeneous nanocatalyst for synthesis of 2,3-dihydroquinazolin-4(1H)-ones, 5-substituted 1H-tetrazoles and polyhydroquinolines. The synthesized catalysts were characterized by FT-IR, TGA, XRD, VSM, EDX, ICP and SEM techniques. These catalysts were recovered by an external magnet and reused several times without significant loss of catalytic efficiency. [GRAPHICS] .

SDS of cas: 120-14-9. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Hajjami, M; Sheikhaei, S; Gholamian, F; Yousofvand, Z or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Metal-free multicomponent synthesis and in vitro antioxidant activity of indolylpyrazolopyrimidines WOS:000647318700001 published article about ANTIINFLAMMATORY ACTIVITY; FUNCTIONALIZATION; INDOLE; NANOCOMPOSITES; CYTOTOXICITY; INHIBITORS; EXTRACT; PDE1 in [Nadiveedhi, Maheshwara Reddy; Shaik, Mahammad Sadik; Krishnammagari, Suresh Kumar; Cirandur, Suresh Reddy] Sri Venkateswara Univ, Dept Chem, Tirupati 51750, Andhra Pradesh, India in 2021.0, Cited 50.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9. Application In Synthesis of 3,4-Dimethoxybenzaldehyde

Multisubstituted indolylpyrazolopyrimidines were synthesized in good yields with base promoted one-pot multicomponent system from aldehyde, ketone, and indolylpyrazolamine. Milder and cost-effective conditions are the highlights of the present protocol. Among the synthesized compounds (4a-j) 4b, 4c, 4e, and 4f have shown significant better in vitro antioxidant activity compared to standard ascorbic acid.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Nadiveedhi, MR; Shaik, MS; Krishnammagari, SK; Cirandur, SR or concate me.. Application In Synthesis of 3,4-Dimethoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about RESISTANT STAPHYLOCOCCUS-AUREUS; DIVISION PROTEIN FTSZ; IN-VITRO; INHIBITORS; CYTOKINESIS; BACTERIA; INSIGHTS, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81973179, 81673284]; Key Project of Major Project of New and Old Kinetic Energy Conversion of Shandong Province. Published in ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER in ISSY-LES-MOULINEAUX ,Authors: Song, D; Zhang, N; Zhang, PP; Zhang, N; Chen, WJ; Zhang, L; Guo, T; Gu, XT; Ma, ST. The CAS is 120-14-9. Through research, I have a further understanding and discovery of 3,4-Dimethoxybenzaldehyde. COA of Formula: C9H10O3

With the increasing incidence of antibiotic resistance, new antibacterial agents having novel mechanisms of action hence are in an urgent need to combat infectious diseases caused by multidrug-resistant (MDR) pathogens. Four novel series of substituted 9-arylalkyl-10-methylacridinium derivatives as FtsZ inhibitors were designed, synthesized and evaluated for their antibacterial activities against various Gram-positive and Gram-negative bacteria. The results demonstrated that they exhibited broad-spectrum activities with substantial efficacy against MRSA and VRE, which were superior or comparable to the berberine, sanguinarine, linezolid, ciprofloxacin and vancomycin. In particular, the most promising compound 15f showed rapid bactericidal properties, which avoid the emergence of drug resistance. However, 15f showed no inhibitory effect on Gram-negative bacteria but biofilm formation study gave possible answers. Further target identification and mechanistic studies revealed that 15f functioned as an effective FtsZ inhibitor to alter the dynamics of FtsZ self-polymerization, which resulted in termination of the cell division and caused cell death. Further cytotoxicity and animal studies demonstrated that 15f not only displayed efficacy in a murine model of bacteremia in vivo, but also no significant hemolysis to mammalian cells. Overall, this compound with novel skeleton could serve as an antibacterial lead of FtsZ inhibitor for further evaluation of drug-likeness. (C) 2021 Elsevier Masson SAS. All rights reserved.

COA of Formula: C9H10O3. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Song, D; Zhang, N; Zhang, PP; Zhang, N; Chen, WJ; Zhang, L; Guo, T; Gu, XT; Ma, ST or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Application In Synthesis of 3,4-Dimethoxybenzaldehyde. Authors Caleffi, GS; Brum, JDC; Costa, AT; Domingos, JLO; Costa, PRR in AMER CHEMICAL SOC published article about in [Caleffi, Guilherme S.; Brum, Juliana de O. C.; Costa, Angela T.; Costa, Paulo R. R.] Univ Fed Rio de Janeiro, Inst Pesquisas Prod Nat, Lab Quim Bioorgan, BR-21941902 Rio De Janeiro, Brazil; [Brum, Juliana de O. C.] Inst Mil Engn, BR-22290270 Rio De Janeiro, Brazil; [Domingos, Jorge L. O.] Univ Estado Rio de Janeiro, Inst Quim, Dept Quim Organ, BR-20550900 Rio De Janeiro, Brazil in 2021.0, Cited 72.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

3-Arylidenechroman-4-ones and 2-arylidene-1-tetralones are hydrogenated to cis-benzylic alcohols in dr’s and er’s up to 99:1 via a C=C and C=O one-pot reduction in the presence of 2-5 mol % Noyori-Ikariya-type Ru-II chiral complexes and HCO2Na as a hydrogen source under asymmetric transfer hydrogenation-dynamic kinetic resolution (ATH-DKR) conditions. The oxidation of theses substrates resulted in the enantioselective synthesis of the natural homoisoflavanone dihydrobonducellin and its carba-analogues.

Application In Synthesis of 3,4-Dimethoxybenzaldehyde. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Caleffi, GS; Brum, JDC; Costa, AT; Domingos, JLO; Costa, PRR or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Liu, ZQ; Li, SN; Zeng, QS; Liu, YJ; You, JM; Ying, AG in ELSEVIER published article about in [Liu, Zhong-Qiu; Li, Sheng-Nan; Zeng, Qing-Shuai; Liu, Yu-Jing; You, Jin-Mao; Ying, An-Guo] Qufu Normal Univ, Coll Chem & Chem Engn, Key Lab Life Organ Anal, Qufu 273165, Shandong, Peoples R China; [Ying, An-Guo] Taizhou Univ, Sch Pharmaceut & Chem Engn, Taizhou 318000, Zhejiang, Peoples R China in 2021, Cited 44. SDS of cas: 120-14-9. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

The preparation of mesoporous poly(ionic liquid)s (MPILs) is critically fundamental for the design of heterogeneous catalysts, whereas traditional methods are difficult to obtain these materials with both well-defined mesoporous structure and unique functionality. Here, HClO4-functionalized MPILs with well-defined mesoporous structure were successfully fabricated, in which the alkene-modified Fe3O4 nanoparticles as structural reinforcer play a vital role for mesoporous structure formation. The MPILs were characterized by N-2 adsorption/desorption, scanning electron microscope (SEM), transmission Electron Microscope (TEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), and vibration sample magnetometry (VSM), and the results confirm that MPILs possess moderate surface area, well-defined mesoporosity, abundant active ionic centers, as well as efficient magnetic recovery. The resulting MPILs show excellent catalytic activity for condensation reaction and Knoevenagel condensation. The kinetic study reveals that the excellent catalytic activity of MPILs is attributed to the synergistic catalysis of mesoporous confinement effect and hydrogen proton from MPILs, albeit with mass transfer resistance produced by mesoporous channels. Further, the catalyst can be recovered using an external magnetic field and reused at least 10 times without a considerable decrease in its catalytic activity. Finally, alkene-modified Fe3O4 nanoparticle-mediated mesoporous construction promotes a textural engineering approach to the development of novel mesoporous materials for other applications.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Liu, ZQ; Li, SN; Zeng, QS; Liu, YJ; You, JM; Ying, AG or concate me.. SDS of cas: 120-14-9

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles