Category: 123-11-5

Name: 4-Methoxybenzaldehyde. Authors Roozifar, M; Hazeri, N; Niya, HF in WILEY published article about in [Roozifar, Majid; Hazeri, Nourallah; Faroughi Niya, Homayoun] Univ Sistan & Baluchestan, Fac Sci, Dept Chem, POB 98135-674, Zahedan, Iran in 2021, Cited 47. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

In this study, three eco-friendly, efficient, and convenient protocols have been reported for one-pot synthesis of 2,4,6-triaryl pyridine, 2-amino-3-cyanopyridine, and polyhydroquinoline derivatives using salicylic acid as a catalyst under solvent-free condition. The reported protocols offer several significant advantages such as the application of a nontoxic, neutral, and cheap catalyst, environmentally friendly conditions, the easy isolation of products by filtering, short reaction times, simple methodology, and good yields.

About 4-Methoxybenzaldehyde, If you have any questions, you can contact Roozifar, M; Hazeri, N; Niya, HF or concate me.. Name: 4-Methoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Oxygen Bridged Bimetallic CuMoO4 Nanocatalyst for Benzylic Alcohol Oxidation; Mechanism and DFT Study WOS:000641292700001 published article about CATALYZED SELECTIVE OXIDATION; AEROBIC OXIDATION; HYDROGEN-PEROXIDE; C-N; COPPER; METAL; ALDEHYDES; NANOPARTICLES; COMPLEXES; EFFICIENT in [Behera, Pradyota Kumar; Choudhury, Prabhupada; Sahu, Santosh Kumar; Sahu, Rashmi Ranjan; Rout, Laxmidhar] Berhampur Univ, Dept Chem, Berhampur 760007, Orissa, India; [Rout, Laxmidhar] IISER, Dept Chem, Berhampur 760010, Odisha, India; [Harvat, Alisha N.; McNulty, Caitlin; Stitgen, Abigail; Scanlon, Joseph] Ripon Coll, Ripon, WI 54971 USA; [Kar, Manoranjan] IIT Patna, Patna 801106, Bihar, India in 2021, Cited 113. Application In Synthesis of 4-Methoxybenzaldehyde. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

Though concept of oxygen bridged bimetallic catalyst for organic reaction is not well understood. Herein, we have tried to explain the concept by experimental as well as its support by full DFT study. We report here a competent protocol for dehydrogenative oxidation of benzylic alcohol using an oxygen bridged bimetallic CuMoO4 nano catalyst. Careful demonstration reveals that oxidation is not effective either with mono-metallic Cu (II) or Mo(VI); instead combination of both the metals through the oxygen bridge [Cu-O-Mo] unexpectedly and interestingly catalyzed the reaction efficiently. The new concept is strongly supported by computational DFT study. DFT study reveals dehydrogenative oxidation is preferred at copper centre over molybdenum and aromatic benzyl alcohols are greatly stabilised. Interaction barrier energy of monometallic CuO and MoO3 catalyst is much higher than bimetallic CuMoO4. Hydrogen transfer has larger barrier heights for CuO (31.5 kcal/mol) and MoO3 (40.3 kcal/mol) than bimetallic CuMoO4.

Welcome to talk about 123-11-5, If you have any questions, you can contact Behera, PK; Choudhury, P; Sahu, SK; Sahu, RR; Harvat, AN; McNulty, C; Stitgen, A; Scanlon, J; Kar, M; Rout, L or send Email.. Application In Synthesis of 4-Methoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Application In Synthesis of 4-Methoxybenzaldehyde. Karimi, M; Mohebali, H; Sadeghi, S; Safarifard, V; Mahjoub, A; Heydari, A in [Karimi, Meghdad; Mohebali, Haleh; Sadeghi, Samira; Mahjoub, Alireza; Heydari, Akbar] Tarbiat Modares Univ, Chem Dept, POB 14155-4838, Tehran, Iran; [Safarifard, Vahid] Iran Univ Sci & Technol, Dept Chem, Tehran 1684613114, Iran published Additive-free aerobic C-H oxidation through a defect-engineered Ce-MOF catalytic system in 2021, Cited 76. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

Ce-UiO-66 MOF, namely cerium-organic framework was prepared through a fast and efficient method under ultrasonic radiation. After preparation, it was identified using some different microscopic and spectroscopic techniques such as PXRD, FT-IR, TG/DTA, BET, BJH, and FE-SEM. The catalytic activity of Ce-UiO-66 MOF was checked in aerobic oxidation of methyl arenas, alcohols and styrene derivatives in a sustainable circumstance with no additives. Moreover, its catalytic activity was surveyed influenced by a number of variables in the ultrasonic synthesis method. Some parameters such as solvent, base, temperature, amount of the catalyst and time were also tested to optimize the aerobic oxidation reaction. After the 10th run, the recycled Ce-MOF showed an acceptable efficiency, which proved its high reusability and stability under optimized conditions. Furthermore, the Ce-UiO-66 was investigated structurally by PXRD method which demonstrated the catalyst stability after the aerobic oxidation reaction.

Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.. Application In Synthesis of 4-Methoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

I found the field of Biochemistry & Molecular Biology; Biophysics; Endocrinology & Metabolism; Physiology very interesting. Saw the article Synthesis of novel tris-chalcones and determination of their inhibition profiles against some metabolic enzymes published in 2021. Quality Control of 4-Methoxybenzaldehyde, Reprint Addresses Burmaoglu, S (corresponding author), Erzincan Binali Yildirim Univ, Tercan Vocat High Sch, TR-24800 Erzincan, Turkey.. The CAS is 123-11-5. Through research, I have a further understanding and discovery of 4-Methoxybenzaldehyde

In this study, we report the synthesis of novel tris-chalcones and testing of human carbonic anhydrase I, and II isoenzymes (hCA I, and hCA II), acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and alpha-glycosidase (alpha-Gly) inhibitors for the development of novel chalcone structures towards for treatment of some diseases. The compounds demonstrated K-i values between 13.6 +/- 1.1 and 50.0 +/- 17.1 nM on hCA I, 9.9 +/- 0.8 and 39.5 +/- 15.1 nM on hCA II, 3.1 +/- 0.2 and 20.1 +/- 1.9 nM on AChE, 4.9 +/- 0.4 and 14.7 +/- 5.2 nM on BChE and 3.9 +/- 0.2 and 22.4 +/- 10.7 nM on alpha-Gly enzymes. The results revealed that novel tris-chalcones can have promising drug potential for glaucoma, leukaemia, epilepsy; Alzheimer’s disease that was associated with the high enzymatic activity of hCA I, hCA II, AChE, and BChE enzymes.

Quality Control of 4-Methoxybenzaldehyde. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Application In Synthesis of 4-Methoxybenzaldehyde. Authors Simeonova, R; Zheleva, D; Valkova, I; Stavrakov, G; Philipova, I; Atanasova, M; Doytchinova, I in MDPI published article about in [Simeonova, Rumyana; Zheleva, Dimitrina; Valkova, Iva; Stavrakov, Georgi; Atanasova, Mariyana; Doytchinova, Irini] Med Univ Sofia, Fac Pharm, Sofia 1000, Bulgaria; [Stavrakov, Georgi; Philipova, Irena] Bulgarian Acad Sci, Inst Organ Chem, Ctr Phytochem, Sofia 1113, Bulgaria in 2021, Cited 61. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

The acetylcholinesterase (AChE) inhibitors are the main drugs for symptomatic treatment of neurodegenerative disorders like Alzheimer’s disease. A recently designed, synthesized and tested hybrid compound between the AChE inhibitor galantamine (GAL) and the antioxidant polyphenol curcumin (CU) showed high AChE inhibition in vitro. Here, we describe tests for acute and short-term toxicity in mice as well as antioxidant tests on brain homogenates measured the levels of malondialdehide (MDA) and glutathione (GSH) and in vitro DPPH, ABTS, FRAP and LPO inhibition assays. Hematological and serum biochemical analyses were also performed. In the acute toxicity tests, the novel AChE inhibitor given orally in mice showed LD50 of 49 mg/kg. The short-term administration of 2.5 and 5 mg/kg did not show toxicity. In the ex vivo tests, the GAL-CU hybrid performed better than GAL and CU themselves; in a dose of 5 mg/kg, it demonstrates 25% reduction in AChE activity, as well as a 28% and 73% increase in the levels of MDA and GSH, respectively. No significant changes in blood biochemical data were observed. The antioxidant activity of 4b measured ex vivo was proven in the in vitro tests. In the ABTS assay, 4b showed radical scavenging activity 10 times higher than the positive control butylhydroxy toluol (BHT). The GAL-CU hybrid is a novel non-toxic AChE inhibitor with high antioxidant activity which makes it a prospective multitarget drug candidate for treatment of neurodegenerative disorders.

Application In Synthesis of 4-Methoxybenzaldehyde. Welcome to talk about 123-11-5, If you have any questions, you can contact Simeonova, R; Zheleva, D; Valkova, I; Stavrakov, G; Philipova, I; Atanasova, M; Doytchinova, I or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Cui, PL; Zhang, D; Guo, XM; Ji, SJ; Jiang, QM in TAYLOR & FRANCIS INC published article about in [Cui, Peng-Lei; Guo, Xiu-Min; Ji, Shu-Jing; Jiang, Qing-Mei] Hebei Agr Univ, Coll Sci, Baoding, Peoples R China; [Zhang, Di] Hebei Agr Univ, Coll Food Sci & Technol, Baoding, Peoples R China in 2021, Cited 28. Safety of 4-Methoxybenzaldehyde. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

A series of novel thiouracil derivatives 9 containing an oxadiazole moiety have been synthesized by structural modification of a lead SecA inhibitor, 2. These compounds have been evaluated for their antibacterial activities against Bacillus amyloliquefaciens, Staphylococcus aureus and Bacillus subtilis. Among them, compounds 9g and 9n exhibited promising antibacterial activities against the tested strains. Compound 9g was also tested for its inhibitory activities against SecA ATPase, and the IC50 value of compound 9g was 19.9 mu g/mL, lower than that of compound 2 (20.8 mu g/mL). Molecular docking work indicates that compound 9g likely occupies the pocket formed by SecA IRA2 and NBD domain.

Safety of 4-Methoxybenzaldehyde. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Rathod, VN; Bansode, ND; Thombre, PB; Lande, MK in [Rathod, Vaishali N.; Bansode, Nilam D.; Thombre, Premkumar B.; Lande, Machhindra K.] Dr Babasaheb Ambedkar Marathwada Univ, Dept Chem, Aurangabad 431004, Maharashtra, India published Efficient one-pot synthesis of polyhydroquinoline derivatives through the Hantzsch condensation using IRMOF-3 as heterogeneous and reusable catalyst in 2021, Cited 39. COA of Formula: C8H8O2. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

A mesoporous Zn-based 2-amino terephthalate metal organic framework (IRMOF-3) catalyst was prepared using the solvothermal method. The synthesized catalyst was characterized by powder X-ray diffraction (XRD), thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDAX), and Brunauer-Emmett-Teller surface area analysis (BET). It was applied as an effective heterogeneous catalyst for the synthesis of one-pot four-component polyhydroquinoline derivatives via the Hantzsch condensation. The present method offers several advantages over other reported methods such as easy separation, mild reaction condition, and excellent yield of desired product. Furthermore, the catalyst can be reused without loss in activity.

COA of Formula: C8H8O2. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Safety of 4-Methoxybenzaldehyde. Authors Gomes, LR; Low, JN; Wardell, JL in ELSEVIER published article about in [Gomes, Ligia R.] Univ Fernando Pessoa, FP ENAS Fac Ciencias Saude, Escola Super Saude UFP, Rua Carlos da Maia 296, P-4200150 Porto, Portugal; [Gomes, Ligia R.] Univ Porto, Dept Quim & Bioquim, REQUIMTE, LAQV,Fac Ciencias, Rua Campo Alegre 687, P-4169007 Porto, Portugal; [Low, John N.; Wardell, James L.] Univ Aberdeen, Dept Chem, Meston Walk AB24 3UE, Old Aberdeen, Scotland; [Wardell, James L.] Fundacao Oswaldo Cruz, Inst Tecnol Farmacos & Farmanguinhos, BR-21041250 Rio De Janeiro, RJ, Brazil in 2021, Cited 33. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

The crystal structures, Hirshfeld surface analysis and PIXEL calculations are reported for (E)-3-(4-methoxyphenyl)-1-(2-hydroxy-5-isoproproxyphenyl)prop-2-en-1-one, 1, and (E)-3-(3-methoxy-4-isopropoxyphenyl)-1-(2-hydroxy-4,6-diisoproproxyphenyl)prop-2-en-1-one, 2. Different sets of C-H…O, C-H…pi, off-set, face-to-face pi…pi and/or C=O…pi intermolecular interactions are displayed by each compound. Due to the bulk of the isoproproxy unit and the consequent steric hindrance in forming aggregates in the solid state, compounds 1 and 2 exhibit larger interplanar angles than do corresponding chalcones with methoxy units. The total stabilization energies of the crystal packing, E-tot distributed as Coulombic (E-coul), polarization (E-pol), dispersion (E-disp), and repulsion (E-rep) have been computed by PIXEL. For compound 1, six motifs (molecule pairs) and for compound 2, with two independent molecules in the asymmetric unit, thirteen motifs are identified by the PIXEL calculations to have energies, -E-tot, above the cut-offvalue of 10 kJ.mol(-1). For each of these motifs, the largest contributor to the E-tot value is the E-disp term, irrespective of the type(s) of interaction(s) connecting the two molecules, if any, in the motifs. (C) 2021 Elsevier B.V. All rights reserved.

Safety of 4-Methoxybenzaldehyde. Welcome to talk about 123-11-5, If you have any questions, you can contact Gomes, LR; Low, JN; Wardell, JL or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Nope, E; Sathicq, AG; Martinez, JJ; Rojas, H; Romanelli, G in ELSEVIER published article about ONE-POT SYNTHESIS; BIGINELLI-TYPE REACTION; MG-AL HYDROTALCITES; SOLVENT-FREE; HETEROGENEOUS CATALYSTS; EFFICIENT SYNTHESIS; IONIC LIQUID; SOLID BASE; MECHANISM; CONDENSATION in [Nope, Eliana; Sathicq, Angel G.; Romanelli, Gustavo] Univ Nacl La Plata, Ctr Invest & Desarrollo Ciencias Aplicadas Dr Jor, CONICET, CINDECA,CCT La Plata,CIC,PBA, Calle 47 257,B1900AJK, La Plata, Argentina; [Martinez, Jose J.; Rojas, Hugo] Univ Pedag & Tecnol Colombia UPTC, Fac Ciencias, Escuela Ciencias Quim, Ave Cent Norte, Tunja, Boyaca, Colombia; [Romanelli, Gustavo] Univ Nacl La Plata, Fac Ciencias Agr & Forestales, Catedra Quim Organ, Ctr Invest Sanidad Vegetal CISaV, Calles 60 & 119 S-N,B1904AAN, La Plata, Argentina in 2021.0, Cited 61.0. Quality Control of 4-Methoxybenzaldehyde. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

Uracil compounds participate in a wide range of biological activities; however, reports on their synthesis using heterogeneous catalysts are scarce. In this work, the multicomponent synthesis of uracil derivatives assisted by layered double hydroxides (LDH) was studied under green chemistry conditions. The incorporation of Ni2+ or Co2+ was successfully performed by co-precipitation method. The yields to uracil derivatives are associated with the presence of weak basic sites and a better interaction of the reagents when the reaction is carried out in solvent-free conditions. The reaction pathway involves the formation of an enone between benzaldehyde and ethyl cyanoacetate, and subsequent reaction with urea, which is assisted by the presence of a basic catalyst. The scope of this synthesis is illustrated with nine examples.

Welcome to talk about 123-11-5, If you have any questions, you can contact Nope, E; Sathicq, AG; Martinez, JJ; Rojas, H; Romanelli, G or send Email.. Quality Control of 4-Methoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Pathaw, L; Khamrang, T; Selvakumaran, B; Murali, M; Prakash, PA; Jaabir, MSM; Velusamy, M in WILEY published article about RUTHENIUM(II) POLYPYRIDYL COMPLEXES; COPPER(I) COMPLEXES; IN-VITRO; CATALYTIC-PROPERTIES; OXIDATIVE STRESS; HIGHLY EFFICIENT; CU(I) COMPLEXES; CANCER-CELLS; PHOTOSENSITIZERS; SERIES in [Pathaw, Larica; Velusamy, Marappan] North Eastern Hill Univ, Dept Chem, Shillong 793022, Meghalaya, India; [Khamrang, Themmila] CI Coll, Dept Chem, Bishnupur, Manipur, India; [Selvakumaran, Balasubramaniam; Murali, Mariappan] Natl Coll Autonomous, Dept Chem, Coordinat & Bioinorgan Chem Res Lab, Tiruchirappalli 620001, Tamil Nadu, India; [Arul Prakash, Pitchan; Mohamed Jaabir, Mohamed Sultan] Natl Coll Autonomous, Dept Biotechnol & Microbiol, Tiruchirappalli, India in 2021, Cited 70. COA of Formula: C8H8O2. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

Copper(I) complexes of the types [Cu(N-N)(PPh3)(2)]NO3(LC41-LC44) and [Cu(N-N)(PPh3)(NO3)] (LC45) carrying 3-substituted 1-pyridine-2-ylimidazo[1,5-a]pyridine (N-N) derivatives and triphenylphosphine (PPh3) ligands have been prepared. The synthesized copper(I)-phosphine complexes were fully characterized by NMR, IR, ESI-MS and UV-visible spectroscopy as well as by cyclic voltammetry. Selected structures such as LC42, LC43 and LC45 were additionally analysed by single-crystal X-ray method, which show that copper(I) centre adopts a highly distorted tetrahedral geometry. The(1)H and(13)C NMR spectral data of the complexes throw light on the nature of metal-ligand bonding. They display d pi-pi* metal-to-ligand charge transfer (MLCT) transition and show quasireversible Cu-I/Cu(II)metal oxidation. Among the copper(I)-phosphine complexes, LC41-LC44 exhibit moderate cytotoxicity (IC50: 24 h, 67-74 mu M; 48 h, 58-70 mu M) against human lung epithelial adenocarcinoma A549 cells, whereas LC45 displays the best activity (IC50: 24 h, 42 mu M; 48 h, 34 mu M) for A549 cancer cell line, which is better than that of the commercial antitumor drug cisplatin. All the complexes also displayed excellent selectivity by being relatively inactive against the human lung epithelial L132 normal cell line with selectivity index (SI) values ranging from 3.4 to 7.4. The complexes block cell cycle progression of A549 cells in G(0)/G(1)phase. FACSVerse analyses are suggestive of reactive oxygen species (ROS) generation and apoptotic cell death induced by the LC41, LC43 and LC45. The induction of apoptosis in A549 cells was shown by Annexin V with propidium iodide (PI) and 4 ‘,6-diamidino-2-phenylindole (DAPI) staining methods and established the ability of LC41, LC43 and LC45 to accumulate in the cell nuclei.

COA of Formula: C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Pathaw, L; Khamrang, T; Selvakumaran, B; Murali, M; Prakash, PA; Jaabir, MSM; Velusamy, M or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles