Category: 123-11-5

I found the field of Biochemistry & Molecular Biology; Chemistry; Pharmacology & Pharmacy very interesting. Saw the article Microwave-assisted Synthesis of Novel Pyrazole Derivatives and their Biological Evaluation as Anti-Bacterial Agents published in 2021. SDS of cas: 123-11-5, Reprint Addresses Hatamjafari, F; Pourshamsian, K (corresponding author), Islamic Azad Univ, Dept Chem, Tonekabon Branch, Tonekabon, Iran.. The CAS is 123-11-5. Through research, I have a further understanding and discovery of 4-Methoxybenzaldehyde

Aims and Objectives: Microwave-assisted condensation of acetophenone 1 and aromatic aldehydes 2 gave chalcone analogs 3, which were cyclized to pyrazole derivatives 6a-f via the reaction with hydrazine hydrate and oxalic acid in the presence of the catalytic amount of acetic acid in ethanol. Materials and Methods: The structural features of the synthesized compounds were characterized by melting point, FT-IR, H-1, C-13 NMR and elemental analysis. Results: The antibacterial activities of the synthesized pyrazoles were evaluated against three gram-positive bacteria, such as Enterococcus durans, Staphylococcus aureus, Bacillus subtilis and two gram-negative bacteria such as Escherichia coli and Salmonella typhimurium. Conclusion: All the synthesized pyrazoles showed relatively high antibacterial activity against S. aureus strain, and none of them demonstrated antibacterial activity against E. coli.

Welcome to talk about 123-11-5, If you have any questions, you can contact Khodadad, H; Hatamjafari, F; Pourshamsian, K; Sadeghi, B or send Email.. SDS of cas: 123-11-5

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Ultrasound-assisted solvent-free synthesis of 3, 4-dihydropyrimidin-2(1H)-ones/thiones using polyindole as a recyclable catalyst WOS:000568456200001 published article about ONE-POT SYNTHESIS; IMPROVED PROTOCOL CONDITIONS; CALCIUM-CHANNEL BLOCKERS; BIGINELLI REACTION; EFFICIENT CATALYST; REUSABLE CATALYST; HETEROPOLY ACID; BROMIDE; DIHYDROPYRIMIDINONES; ESTERS in [Handore, Kalpana N.; Chabukswar, Vasant V.; Pawar, Digamber] Savitribai Phule Pune Univ, Dept Chem, Nowrosjee Wadia Coll, Pune 411001, Maharashtra, India; [Dallavalle, Sabrina] Univ Milan, Dept Food Environm & Nutr Sci, Milan, Italy in 2021, Cited 33. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5. Name: 4-Methoxybenzaldehyde

This paper describes the synthesis of polyindole by chemical oxidative polymerization using copper chloride as oxidant. Polyindole was characterized by various spectroscopic techniques like FT-IR, XRD, FESEM, and TGA. The XRD pattern confirms the semi-crystalline nature of polyindole. An efficient, solvent-free, ultrasound-assisted synthesis of biologically active 3,4-dihydropyrimidin-2(1 H)-one/thiones (DHPM) derivatives is reported by using polyindole as a recyclable catalyst. The advantages of this method are mild reaction conditions, short reaction time, excellent yields with high purity and low loading of catalyst. Polyindole can be used several times without loss of significant catalytic activity as compared to the other reported catalysts. Factors affecting on the rate of reaction, like use of ultrasonication, temperature, solvent, amount, and recyclability of catalyst have also been studied.

Name: 4-Methoxybenzaldehyde. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: 123-11-5. Authors Reddy, GM; Garcia, JR; Subbaiah, MV; Wen, JC in WILEY published article about in [Reddy, Guda Mallikarjuna] Ural Fed Univ, Chem Engn Inst, Ekaterinburg 620002, Russia; [Garcia, Jarem Raul] Univ Ponta Grossa, Dept Chem, Av Carlos Cavalcanti,4748 Campus Uvaranas,Bloco L, BR-84030900 Ponta Grossa, Parana, Brazil; [Subbaiah, Munagapati Venkata; Wen, Jet-Chau] Natl Yunlin Univ Sci & Technol, Res Ctr Soil & Water Resources & Nat Disaster Pre, 123,Sect 3,Univ Rd, Touliu 640, Yunlin, Taiwan; [Wen, Jet-Chau] Natl Yunlin Univ Sci & Technol, Dept Safety Hlth & Environm Engn, Touliu, Taiwan in 2021, Cited 51. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

Benzothiazole-tethered pyranopyrazoles derivatives were prepared via environmentally favorable conditions, which included eco-friendly catalyst, ethanol-water solvent, one-pot reaction, and atom- and step-economy procedures. Excellent yield of the products was observed. Besides, all products were screened for their antimicrobial behavior. From the biological results, it was seen that most of the compounds possessed high to moderate antimicrobial properties. Compound 6a gave prominent antimicrobial property followed by 6d, 6l, and 6n. In addition, computer-aided studies of the active compounds were also conducted. In this, selected compounds were docked into the intercalation site of DNA of the DNA-gyrase complex. From these results, the highest binding energy of -10.1 kcal/mol was for 6a against DNA-gyrase. This is the first eco-friendly synthetic method for the preparation of benzothiazole-pyranopyrazoles and the synthetic effort in this study may serve as a model for additional environmentally benign reactions. The biological results may prompt further studies related to antibiotic drugs.

Recommanded Product: 123-11-5. Welcome to talk about 123-11-5, If you have any questions, you can contact Reddy, GM; Garcia, JR; Subbaiah, MV; Wen, JC or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Computed Properties of C8H8O2. Authors Ghobadifard, M; Safaei, E; Radovanovic, PV; Mohebbi, S in ROYAL SOC CHEMISTRY published article about in [Ghobadifard, Mahdieh; Safaei, Elham; Mohebbi, Sajjad] Univ Kurdistan, Dept Chem, Sanandaj 6617715175, Iran; [Ghobadifard, Mahdieh; Radovanovic, Pavle V.] Univ Waterloo, Dept Chem, 200 Univ Ave W, Waterloo, ON, Canada; [Ghobadifard, Mahdieh; Mohebbi, Sajjad] Univ Kurdistan, Res Ctr Nanotechnol, Sanandaj 6617715175, Iran in 2021, Cited 74. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

We investigated the photocatalytic performance of a magnetic nanohybrid of CoFe2O4 and TiO2 hetero-nanostructures (TiO2/CoFe2O4) conjugated with zinc tetrakis carboxyphenyl porphyrin (ZnTCPP) for controlled oxidation of alcohols to aldehydes under visible light. The photocatalyst was prepared by nucleating titania on pre-formed CoFe2O4 nanoparticles, generating anatase TiO2/CoFe2O4 hetero-nanostructures upon annealing at 450 degrees C. Then, they were conjugated with ZnTCPP resulting in ZnTCPP-TiO2/CoFe2O4 nanohybrid materials, which were characterized in detail by different structural and spectroscopic methods. The ZnTCPP-TiO2/CoFe2O4 nanostructures have an average size of 21 nm and show ferromagnetic behavior with a magnetization saturation of 47 emu g(-1), a remanence of 22 emu g(-1), and a coercivity of ca. 1000 Oe. The photocatalytic conversion of alcohols up to 87% under visible light was achieved by using this hybrid nanomaterial. Such a high catalytic performance can be related to the low charge recombination rate of the ZnTCPP-TiO2/CoFe2O4 nanostructures. The magnetic hybrid nanostructures reported in this work have excellent potential as visible light photocatalysts with advantages of high efficiency, selectivity, stability, and easy separation.

Computed Properties of C8H8O2. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

I found the field of Chemistry very interesting. Saw the article Combining photoredox catalysis and oxoammonium cations for the oxidation of aromatic alcohols to carboxylic acids published in 2021. SDS of cas: 123-11-5, Reprint Addresses Leadbeater, NE (corresponding author), Univ Connecticut, Dept Chem, 55 North Eagleville Rd, Storrs, CT 06269 USA.. The CAS is 123-11-5. Through research, I have a further understanding and discovery of 4-Methoxybenzaldehyde

A methodology is reported for converting alcohols to the corresponding carboxylic acids. A dual catalytic system involving a merger of photoredox catalysis and 4-acetamido-TEMPO is employed to carry out this oxidation process. (C) 2020 Elsevier Ltd. All rights reserved.

Welcome to talk about 123-11-5, If you have any questions, you can contact Nandi, J; Hutcheson, EL; Leadbeater, NE or send Email.. SDS of cas: 123-11-5

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Quality Control of 4-Methoxybenzaldehyde. Authors Soto, M; Gotor-Fernandez, V; Rodriguez-Solla, H; Baratta, W in WILEY-V C H VERLAG GMBH published article about in [Soto, Martin; Gotor-Fernandez, Vicente; Rodriguez-Solla, Humberto] Univ Oviedo, Dept Quim Organ & Inorgan, Ave Julian Claveria 8, E-33006 Oviedo, Spain; [Baratta, Walter] Univ Udine, Dipartimento Sci Agroalimentari Ambientali & Anim, Via Cotonoficio 108, I-33100 Udine, Italy in 2021.0, Cited 45.0. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

The transfer hydrogenation of flavanones and ortho-hydroxychalcones catalyzed by ruthenium pincer complexes RuCl(CNNPh)(disphosphine) has allowed the synthesis of ortho-hydroxy 1,3-diarypropanols in 80-88 % yield, under mild reaction conditions and short reaction times (1 h) in 2-propanol. The amount of the co-catalyst NaOiPr has been found crucial for the selective reduction of flavanones to ortho-hydroxy 1,3-diarypropanols vs. flavan-4-ols. Preliminary results show that with pincer catalysts bearing (S,R)-Josiphos, flavanone is reduced to the corresponding (S)-alcohol in moderate conversion (36 %) and up to 92 % ee.

Welcome to talk about 123-11-5, If you have any questions, you can contact Soto, M; Gotor-Fernandez, V; Rodriguez-Solla, H; Baratta, W or send Email.. Quality Control of 4-Methoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 123-11-5. In 2021 EUR J MED CHEM published article about DRUG DISCOVERY; LEISHMANIA; DESIGN; DOCKING; ANTIBACTERIAL; METHOTREXATE; SYSTEM; TARGET in [Bibi, Maria; Farooq, Umar; Ullah, Azmat; Khan, Farhan A.; Rashid, Umer] COMSATS Univ Islamabad, Dept Chem, Abbottabad Campus, Abbottabad 22060, Khyber Pakhtunk, Pakistan; [Qureshi, Naveeda Akhter; Shaheen, Nargis] Quaid I Azam Univ, Dept Anim Sci, Islamabad 45320, Pakistan; [Sadiq, Abdul] Univ Malakand, Fac Biol Sci, Dept Pharm, Dir L 18000, KP, Pakistan; [Hassan, Abbas] Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan; [Asghar, Irfa; Umer, Duaa] COMSATS Univ Islamabad, Dept Biotechnol, Abbottabad Campus, Abbottabad 22060, Khyber Pakhtunk, Pakistan; [Salman, Muhammad] Natl Inst Hlth NIH, Dept Microbiol, Islamabad 45320, Pakistan; [Bibi, Ahtaram] Kohat Univ Sci & Technol, Fac Phys Sci, Dept Chem, Kohat 26000, Kp, Pakistan in 2021, Cited 42. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

To tackle leishmaniasis, search for efficient therapeutic drug targets should be pursued. Dihydrofolate reductase (DHFR) is considered as a key target for the treatment of leishmaniasis. In current study, we are interested in the design and synthesis of selective antifolates targeting DHFR from L. major. We focused on the development of new antifolates based on 3,4-dihydropyrimidine-2-one and 5-(3,5-dimethoxybenzyl)pyrimidine-2,4-diamine motif. Structure activity relationship (SAR) studies were performed on 4-phenyl ring of dihydropyrimidine (26-30) template. While for 5-(3,5-dimethoxybenzyl) pyrimidine-2,4-diamine, the impact of different amino acids (valine, tryptophan, phenylalanine, and glutamic acid) and two carbon linkers were explored (52-59). The synthesized compounds were assayed against LmDHFR. Compound 59 with the IC50 value of 0.10 mu M appeared as potent inhibitors of L. major. Selectivity for parasite DHFR over human DHFR was also determined. Derivatives 55-59 demonstrated excellent selectivity for LmDHFR. Highest selectivity for LmDHFR was shown by compounds 56 (SI = 84.5) and 58 (SI = 87.5). Compounds Antileishmanial activity against L. major and L. donovani promastigotes was also performed. To explore the interaction pattern of the synthesized compounds with biological macromolecules, the docking studies were carried out against homology modelled LmDHFR and hDHFR targets. (C) 2020 Elsevier Masson SAS. All rights reserved.

SDS of cas: 123-11-5. Welcome to talk about 123-11-5, If you have any questions, you can contact Bibi, M; Qureshi, NA; Sadiq, A; Farooq, U; Hassan, A; Shaheen, N; Asghar, I; Umer, D; Ullah, A; Khan, FA; Salman, M; Bibi, A; Rashid, U or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Computed Properties of C8H8O2. Authors Sarkar, TK; Saraswat, V; Mitra, RK; Obot, IB; Yadav, M in ELSEVIER published article about in [Sarkar, Tarun Kanti; Saraswat, Vandana; Mitra, Ranjeet Kumar; Yadav, Mahendra] Indian Inst Technol ISM, Dept Chem, Dhanbad 826004, Bihar, India; [Obot, I. B.] King Fahd Univ Petr & Minerals, Ctr Res Excellence Corros, Res Inst, Dhahran 31261, Saudi Arabia in 2021, Cited 82. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

Present investigation focused on to study the corrosion inhibition capabilities of pyrimidine derivatives; MPA [4,6-bis(4-methoxyphenyl) pyrimidin-2-amine] and CPA [4,6-bis(4-chlorophenyl) pyrimidin-2-amine] for oil well/tubing steel (N80 steel) in 15 % HCl solution. Corrosion inhibition efficiency of both inhibitors increases on increasing the concentration and decreases on increasing the temperature. The studied organic compounds show excellent corrosion mitigation properties with highest efficiency of 99.5 % for MPA and 94.7 % for CPA at a considerably low dosage of 250 mu M L-1. Adsorption of both inhibitors obeyed Langmuir adsorption isotherm and nature of adsorption is mixed type adsorption. Potentiodynamic polarization studies showed that both the compounds adsorb at the cathodic and anodic sites of the substrate surface to mitigate corrosion process and both inhibitors act as mixed type corrosion inhibitor. The surface study uninhibited and inhibited sample was done through SEM, EDX, AFM, FT-IR and XPS analysis and suggested the formation of protective layer of inhibitor molecules on the N80 steel surface to mitigate its corrosion. The theoretical analysis (DFT and Monte Carlo simulations) of both inhibitors correlates the experimental findings.

Welcome to talk about 123-11-5, If you have any questions, you can contact Sarkar, TK; Saraswat, V; Mitra, RK; Obot, IB; Yadav, M or send Email.. Computed Properties of C8H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Mechanistic Studies on Photoinduced Catalytic Olefin Migration Reactions at the Pd(II) Centers of a Porous Crystal, Metal-Macrocycle Framework WOS:000600657000001 published article about ORGANIC FRAMEWORKS; HYDROGEN STORAGE; ISOMERIZATION; DIMERIZATION; ADSORPTION; ETHYLENE in [Yonezawa, Hirotaka; Han, Mengying; Tashiro, Shohei; Shionoya, Mitsuhiko] Univ Tokyo, Grad Sch Sci, Dept Chem, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1130033, Japan; [Shiraogawa, Takafumi; Ehara, Masahiro] Inst Mol Sci, Okazaki, Aichi 4448585, Japan; [Shiraogawa, Takafumi; Ehara, Masahiro] SOKENDAI, Okazaki, Aichi 4448585, Japan in 2021.0, Cited 47.0. Formula: C8H8O2. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

Porous crystals with well-defined active metal centers on the pore surface have high potential as heterogeneous metal catalysts. We have recently demonstrated that a porous molecular crystal, metal-macrocycle framework (MMF), catalyzes olefin migration reactions by photoactivation of its (PdCl2)-Cl-II moieties exposed on the crystalline channel surface. Herein we report a mechanistic study of the photoinduced olefin migration reactions at the Pd-II active centers of MMF. Several experiments, including a deuterium scrambling study, revealed that olefin migration is catalyzed via an alkyl mechanism by in situ generated Pd-H species on the channel surface during photoirradiation. This proposed mechanism was further supported by DFT and ONIOM calculations.

Welcome to talk about 123-11-5, If you have any questions, you can contact Yonezawa, H; Shiraogawa, T; Han, MY; Tashiro, S; Ehara, M; Shionoya, M or send Email.. Formula: C8H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Formula: C8H8O2. Authors Asressu, KH; Chan, CK; Wang, CC in AMER CHEMICAL SOC published article about in [Asressu, Kesatebrhan Haile; Chan, Chieh-Kai; Wang, Cheng-Chung] Acad Sinica, Inst Chem, Taipei 115, Taiwan in 2021.0, Cited 67.0. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

We developed a facile and green one-pot synthetic method for substituted 1,3,5-triaryl-1,5-diketones by Claisen-Schmidt condensation following Michael addition reaction of aryl ketones and aryl aldehydes under a transition-metal-free condition. This convenient one-pot synthetic strategy has several advantages, including being transition-metal-free, having no extra additives or reagents, having a broad substrate scope, having a high isolated yield, having a minimum amount of base employment, having a shorter reaction time, use of cheap starting materials, cost-effectiveness, and being environment friendly. Some of the chemical structures of 1,5-diketones were confirmed by X-ray single-crystal diffraction analysis. The application of 1,5-diketones was demonstrated in the preparation of 2,4,6-triaryl pyridine derivatives under a catalyst-free system using ammonium acetate as a nitrogen source.

Welcome to talk about 123-11-5, If you have any questions, you can contact Asressu, KH; Chan, CK; Wang, CC or send Email.. Formula: C8H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles