Category: 123-11-5

Jarrahi, M; Tayebee, R; Maleki, B; Salimi, A in [Jarrahi, Mahbube; Tayebee, Reza; Maleki, Behrooz] Hakim Sabzevari Univ, Sch Sci, Dept Chem, Sabzevar 9617976487, Iran; [Salimi, Alireza] Ferdowsi Univ Mashhad, Fac Sci, Dept Chem, Mashhad, Razavi Khorasan, Iran published One-pot multicomponent green LED photoinduced synthesis of chromeno[4,3-b]chromenes catalyzed by a new nanophotocatalyst histaminium tetrachlorozincate in 2021, Cited 57. Recommanded Product: 123-11-5. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

Histaminium tetrachlorozincate nanoparticles are prepared, characterized and applied as an effective and recoverable photocatalyst in the one-pot, green and multi-component synthesis of various chromenes by the reaction of dimedone and/or 1,3-cyclohexanedione, arylaldehyde and 4-hydroxycoumarin in high yields under solventless conditions at ambient temperature. This new catalyst is characterized by FT-IR, XRD, EDX, NMR, SEM and TEM techniques. The incorporation of histaminium ions into the framework of ZnCl42- significantly affected the photocatalytic activity of tetrachlorozincate such that good reusability and recyclability are attained. Moreover, reactive species such as O-2(-) and hydroxyl radicals have proved to be active species in the presented photocatalytic reaction. In addition, the hot filtration test confirms enough stability of the photocatalyst and no significant leaching and destruction of the framework in the course of the reaction. The major advantages of the presented methodology include easy work-up, cost effectiveness, nontoxic nature, broad substrate scope, 100% atom economy, ease of separation, and environment friendly reaction conditions. Finally, the catalyst could be reused many times without significant loss of activity.

Recommanded Product: 123-11-5. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Jarrahi, M; Tayebee, R; Maleki, B; Salimi, A or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Product Details of 123-11-5. Authors Obe, FO; Davis, RA; Spurlock, J; Barnes, MMG; Lindvall, T; Wendorf, MS; Delach, C; Ferrence, GM; Standard, JM; Hitchcock, SR in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Obe, Fatima Olayemi; Davis, Ryan A.; Spurlock, Jennifer; Barnes, Morgan M. Grunloh; Lindvall, Tyler; Wendorf, Micah S.; Delach, Christina; Ferrence, Gregory M.; Standard, Jean M.; Hitchcock, Shawn R.] Illinois State Univ, Dept Chem, Normal, IL 61790 USA in 2021.0, Cited 32.0. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

A series of Ephedra based oxadiazinones have been prepared, acylated, and examined in the asymmetric conjugate addition reaction with Grignard reagents in the presence of copper(I) bromide-dimethyl sulfide complex. The highest diastereoselectivity that was obtained in the conjugate addition reaction was observed with the (1R,2S)-ephedrine based N-4-methyloxadiazinone (5:1 d.r.) favoring the formation of the (S)-configuration of the conjugate addition product. Efforts to enhance the level of diaster-eoselection via increasing the steric volume of the stereo-directing N-4-substituent of the oxadiazinone (N-4- = p-methoxyphenyl or -isopropyl) led to an observed decrease in the level of diastereoselection. A computational study was conducted to examine the conformations adopted by the N-4-methyloxadiazinone vs. the N-4-isopropyl-oxadiazinone that yielded the lower diastereoselectivity. An argument is made for the stereoelectronic properties of the N-4-substituent being the cause of both the moderate diastereoselectivity and the unexpected facial preference for the conjugate addition. (C) 2021 Elsevier Ltd. All rights reserved.

Product Details of 123-11-5. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Obe, FO; Davis, RA; Spurlock, J; Barnes, MMG; Lindvall, T; Wendorf, MS; Delach, C; Ferrence, GM; Standard, JM; Hitchcock, SR or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Catalytic Photoredox Allylation of Aldehydes Promoted by a Cobalt Complex WOS:000603454300001 published article about CARBONYL-COMPOUNDS; ASYMMETRIC ALLYLATION; ALLYLIC ACETATES; METAL-COMPLEXES; EFFICIENT; HALIDES; FUNCTIONALIZATION; TRANSFORMATIONS; IMINES in [Gualandi, Andrea; Rodeghiero, Giacomo; Moreno-Cabrerizo, Cristina; Foucher, Charles; Marchini, Marianna; Ceroni, Paola; Giorgio Cozzi, Pier] Alma Mater Studiorum Univ Bologna, Dipartimento Chim G Ciamician, Via Selmi 2, I-40126 Bologna, Italy; [Rodeghiero, Giacomo; Perciaccante, Rossana; Jansen, Thomas Paul] Cyanagen Srl, Via Stradelli Guelfi 40-C, I-40138 Bologna, Italy; [Moreno-Cabrerizo, Cristina] Univ Alicante, Fac Ciencias, Dept Quim Organ, E-03080 Alicante, Spain; [Moreno-Cabrerizo, Cristina] Univ Alicante, Fac Ciencias, Ctr Innovac Quim Avanzada ORFEO CINQA, E-03080 Alicante, Spain; [Foucher, Charles] Ecole Natl Super Chim Paris, 11 Rue Pierre & Marie Curie, F-75231 Paris 05, France in 2021, Cited 70. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5. Recommanded Product: 123-11-5

The preparation of homoallylic alcohols by addition of organometallic allyl compounds to carbonyls is an important strategy in organic chemistry. Allylating organometallic cobalt species can be generated employing stoichiometric quantities of Zn acting as reductant. To avoid the employment of stoichiometric amount of Zn, we have developed an allylation reaction of aromatic and aliphatic aldehydes promoted by photoredox catalysis in the presence of a cobalt complex, and we present herein a full account of our research. In the presence of the abundant CoBr2 (10 mol %), 4,4 ‘-di-tert-butyl-2,2 ‘-dipyridyl (dtbbpy, 10 mol %), allyl acetate (3 equiv.), [Ir(dtbbpy)(ppy)(2)]PF6 (ppy=2-phenylpyridine, 2 mol %), and N,N-diisopropylethylamine (4 equiv.), an allylation of aldehydes is taking place, in moderate to good yields. Substrates scope, limitations, and photophysical investigations of this new process are reported.

About 4-Methoxybenzaldehyde, If you have any questions, you can contact Gualandi, A; Rodeghiero, G; Perciaccante, R; Jansen, TP; Moreno-Cabrerizo, C; Foucher, C; Marchini, M; Ceroni, P; Cozzi, PG or concate me.. Recommanded Product: 123-11-5

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Salimi, M; Esmaeli-nasrabadi, F; Sandaroos, R in [Salimi, Mehri; Esmaeli-nasrabadi, Farzaneh; Sandaroos, Reza] Univ Birjand, Fac Sci, Dept Chem, POB 97175-615, Birjand, Iran published Effective and selective aerobic oxidation of primary and secondary alcohols using CoFe2O4@HT@Imine-Cu(II)and TEMPO in the air atmosphere in 2021, Cited 54. Computed Properties of C8H8O2. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

In this study, we present a versatile and easy procedure for modifying a cobalt ferrite nanoparticle step by step. A new nanocatalyst was prepared via Cu(II)immobilized onto CoFe2O4@HT@Imine. The catalyst was fully characterized by Fourier-transform infrared (FT-IR), energy-dispersive X-ray spectroscopy (EDX), field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), and vibrating sample magnetometer (VSM) analyses. The current procedure as a green protocol offers benefits including a simple operational method, an excellent yield of products, mild reaction conditions, minimum chemical wastes, and short reaction times. Without any significant reduction in the catalytic performance, up to five recyclability cycles of the catalyst were obtained. The optimization results suggest that the best condition in the oxidation of benzyl alcohol derivatives is 0.003 g of the CoFe2O4@HT@Imine-Cu(II)catalyst, TEMPO, at 70 degrees C under solvent-free condition and air.

Computed Properties of C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Salimi, M; Esmaeli-nasrabadi, F; Sandaroos, R or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

I found the field of Chemistry very interesting. Saw the article KSCN and K2CO3 mediated one-pot synthesis of cyclopropanyl coumarin derivatives published in 2021.0. Formula: C8H8O2, Reprint Addresses Shivashankar, K (corresponding author), Bangalore Univ, Dept Chem, Cent Coll Campus, Bangalore, Karnataka, India.. The CAS is 123-11-5. Through research, I have a further understanding and discovery of 4-Methoxybenzaldehyde

A novel and efficient one-pot method has been developed for the synthesis of cyclopropanes by the cyclization of 4-bromomethylcoumrains, benzaldehydes and active methylene groups in 1:1 acetonitrile and water solvent in the presence of KSCN and K2CO3 as a catalyst at room temperature for 2-5 h. The significant attraction of this procedure is environmentally benign, simple procedure, the ready accessibility of the catalyst, excellent yield and mild reaction conditions. The structure of the target molecule (4b) was confirmed by X-ray diffraction. [GRAPHICS] .

Formula: C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Imrankhan, M; Shivashankar, K or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Haghighi, AJ; Mokhtari, J; Karimian, K in SPRINGER published article about CONDENSATION; CARBENES in [Haghighi, Ali Javaheri; Mokhtari, Javad] Islamic Azad Univ, Dept Chem, Sci & Res Branch, Tehran, Iran; [Karimian, Khashayar] Univ Tehran, Inst Biochem & Biophys, POB 13145-1384, Tehran, Iran in 2021, Cited 21. Category: indole-building-block. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

N-PEGylated-thiazolium salt is used as efficient catalyst for the benzoin condensation. The catalyst was synthesized by reaction of activated polyethylene glycol 10,000 (PEG-10000) with 4-methyl-5-thiazoleethanol (sulfurol). Reaction mixture undergoes temperature-assisted phase transition and catalyst separated by simple filtration. After reaction course, catalyst can be recycled and reused without any apparent loss of activity which makes this process cost effective and hence ecofriendly. Synthesized benzoins and acyloins by this method have been characterized on the basis of melting point and(1)H-NMR spectral studies. [GRAPHICS] .

Category: indole-building-block. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Haghighi, AJ; Mokhtari, J; Karimian, K or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Microwave-assisted hydrodistillation of the essential oil from AlgerianPimpinella anisumseeds WOS:000560016600001 published article about FRUIT ESSENTIAL OIL; ANISEED PIMPINELLA-ANISUM; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; CHEMICAL-COMPOSITION; ROSEMARY LEAVES; CARBON-DIOXIDE; KINETIC-DATA; EXTRACTION; L. in [Boumahdi, Yamina; Moghrani, Houria; Nasrallah, Noureddine; Maachi, Rachida] USTHB, Fac Mech Engn & Proc Engn, Lab React Engn, PB 32 El Alia, Algiers 16111, Algeria; [Ouarek, Salima] Algerian Res & Dev Ctr, Grp Saidal, Lab Microbiol, Route Baraki, Algiers, Algeria in 2021, Cited 63. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5. SDS of cas: 123-11-5

Essential oils (EOs) from anise seeds (Pimpinella anisum) collected in the Algerian region were extracted by microwave-assisted hydrodistillation (MAHD) and hydrodistillation (HD). The oil yield (%), chemical composition, energetic consumption and the antimicrobial properties were evaluated of the obtained EO. The yields obtained by both processes were 2.81 +/- 0.01% for 90 minutes and 3.30 +/- 0.05% for 330 minutes for MAHD and HD, respectively. The determination of the chemical composition of EOs by GC-MS revealed the presence of a majority compound,trans-anethole 81.52% and 91.31% for MAHD and HD, respectively. The other main compounds present in the oils for MAHD and HD were, respectively: methyl chavicol (estragole) (0.63%-1.39%),cis-anethole (0.23%-0.34%), anisaldehyde (1.1%-1.57%), anisyl methyl ketone (0.28%-0.13%),trans-methyl isoellgenol (0.31%-0.17%),gamma-himachalene (0.5%-0.36%),trans-pseudoisoeugenyl 2-methylbutyrate (6.53%-2.53%) and epoxy-pseudoisoeugenyl 2-methylbutyrate (2.01%-0.56%). The EO obtained by MAHD detected other compounds, fenchone 0.41%, limonene 0.68%,cis-jasmolacatone extra C 0.41%,trans-isolongifolanone 0.2% and alpha-himachalene 0.16%. The energetic consumption by MAHD was significantly less than HD. Theoretical data from mathematical modelling were compared with practical data, and the coefficient of determination was between 0.93 and 0.97. The sensibility of bacterial strains to the essential oil obtained by MAHD is marked relatively to that obtained by HD, and for the sensibility of fungal strains, it was conserved. The MAHD process revealed a good yield of anise seeds EOs while reducing extraction time and energetic consumption. The EO extracted by this process revealed the presence of other compounds while improving antibacterial activity.

SDS of cas: 123-11-5. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Boumahdi, Y; Moghrani, H; Nasrallah, N; Ouarek, S; Maachi, R or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Chu, PC; Wu, YC; Chen, CY; Hung, YS; Chang, CS in FUTURE SCI LTD published article about in [Chu, Po-Chen] China Med Univ, Dept Cosmeceut, Taichung 40402, Taiwan; [Chu, Po-Chen] China Med Univ, Grad Inst Cosmeceut, Taichung 40402, Taiwan; [Chu, Po-Chen; Chang, Chih-Shiang] China Med Univ, Drug Dev Ctr, Taichung 40402, Taiwan; [Wu, Yu-Chieh; Chen, Chien-Yu; Hung, Yu-Syuan; Chang, Chih-Shiang] China Med Univ, Sch Pharm, Coll Pharm, Taichung 40402, Taiwan in 2021, Cited 35. Computed Properties of C8H8O2. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

Aim: Tumor cells adapt to hypoxic microenvironments by releasing the key transcription factor HIF-1 alpha, which promotes angiogenesis, glycolytic phenotype, metastasis and erythropoiesis, allowing proliferation amid low oxygen levels. Therefore, therapeutic targeting of HIF-1 alpha represents a viable strategy for cancer therapy. Methods & Results: The authors synthesized a series of novel tetrahydroquinazoline derivatives in six steps and demonstrated that their development had a unique ability to suppress HIF-1 alpha expression through proteasomal degradation. Conclusion: Among these compounds, CDMP-TQZ (8bf) exhibited the highest antiproliferative potency in human cancer cells, in part through downregulation of HIF-1 alpha.

Computed Properties of C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Chu, PC; Wu, YC; Chen, CY; Hung, YS; Chang, CS or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Ren, SJ; Fu, JH; Cheng, DP; Li, XN; Xu, XL in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Ren, Shujian; Fu, Jiahui; Li, Xiaonian; Xu, Xiaoliang] Zhejiang Univ Technol, Coll Chem Engn, Hangzhou 310014, Peoples R China; [Cheng, Dongping] Zhejiang Univ Technol, Coll Pharmaceut Sci, Hangzhou 310014, Peoples R China in 2021.0, Cited 109.0. Recommanded Product: 123-11-5. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

Induced by visible light, a green approach for the highly substituted trifluoromethyl olefins has been developed by using alkyl boronic acid as a carbon radical precursor and the Boc-modified trifluoromethylated Baylis-Hillman adduct (BMTBHA) as an acceptor. This method starts from 1,1-disubstituted olefins without the external stoichiometric oxidant. (C) 2021 Elsevier Ltd. All rights reserved.

About 4-Methoxybenzaldehyde, If you have any questions, you can contact Ren, SJ; Fu, JH; Cheng, DP; Li, XN; Xu, XL or concate me.. Recommanded Product: 123-11-5

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Computed Properties of C8H8O2. In 2020 J IRAN CHEM SOC published article about BIOLOGICAL EVALUATION; SCHIFF-BASE; DNA-BINDING; METAL-COMPLEXES; ANTIBACTERIAL; AGENTS; IDENTIFICATION; NANOCOMPOSITE; PYRIMIDINES; ANALOGS in [Arshad, Mohammad] Shaqra Univ, Dept Basic Sci, Coll Med, Al Dawadmi, Saudi Arabia in 2020, Cited 67. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

An adequate enhancement in the development of resistance by microbial pathogens against the available chemotherapeutic agents prompted us to find out some new chemotherapeutic agents with significant therapeutic effect as antimicrobials. The present study reported the designing of 6-(1H-indol-3-yl)-4,5 ‘-bipyrimidine-2-amine (2) and its Schiff’s bases (3-12), and the computational studies were performed to assess properties (drug likeness and physicochemical). The computationally bioactive compounds (1-12) were then followed for synthesis, characterization, antimicrobial therapeutic effect and percent viability of cells. The antimicrobial therapeutic effect was obtained by disk diffusion method, in terms of zone of inhibition and minimum inhibitory concentration against the gram-positive and gram-negative bacteria [S. aureus (ATCC-25923), S. epidermidis (ATCC-29887)], [E. coli (ATCC-25922), P. mirabilis (ATCC-25933)]. The antimicrobial screening findings reveled that all the compounds (1-12) possessed very good activity and strongly recommended the computational results. The antibiotic ciprofloxacin and the solvent DMSO were used as positive and negative control in the study. The percent viability of the cells was observed using HepG2 cells by MTT assay and noticed that the percent viability of the cells was found in the range 93-97% at lowest concentration 3.125 mu M while 73-77% at the highest 100 mu M. All the compounds (1-12) and ciprofloxacin were then applied for molecular docking assessment to estimate the H-bonding with the residues of GlcN-6-P-synthase, and the findings revealed that significant H-bonding was observed with the binding affinity in the range of – 8.4 to 6.7 kcal/mol and – 7.6 to 6.0 kcal/mol, respectively. Graphic abstract

About 4-Methoxybenzaldehyde, If you have any questions, you can contact Arshad, M or concate me.. Computed Properties of C8H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles