Category: 123-11-5

Dejardin, C; Renou, A; Maddaluno, J; Durandetti, M in [Dejardin, Claire; Renou, Amaury; Maddaluno, Jacques; Durandetti, Muriel] Normandie Univ, UNIROUEN, INSA Rouen, CNRS,Lab COBRA UMR 6014 & FR 3038, F-76000 Rouen, France published Nickel-Catalyzed Electrochemical Cyclization of Alkynyl Aryl Iodide and the Domino Reaction with Aldehydes in 2021, Cited 42. Recommanded Product: 4-Methoxybenzaldehyde. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

An intramolecular carbometallation of a triple bond promoted by electrochemistry and mediated by nickel catalysis is described. This domino process transforms various aryl halides bearing a propargyl chain into substituted heterocycles in one single operation, with high stereoselectivities and in good to high yields. This reaction, characterized by a cyclic voltammetry set of experiments, proceeds following a syn-exo-dig cyclization process. When run at 80 degrees C, vinylbenzofuranes that are suitable substrates for cycloaddition reactions are obtained.

Recommanded Product: 4-Methoxybenzaldehyde. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Dejardin, C; Renou, A; Maddaluno, J; Durandetti, M or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Mehta, J; Aryal, P; Reddy, VP in WILEY-V C H VERLAG GMBH published article about METAL-FREE; NUCLEOPHILIC TRIFLUOROMETHYLATION; ASYMMETRIC-SYNTHESIS; KETONES; AMINES; IMINES in [Mehta, Jatin; Aryal, Puspa; Prakash Reddy, V.] Missouri Univ Sci & Technol, Dept Chem, Rolla, MO 65409 USA in 2021, Cited 39. Category: indole-building-block. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

The C(sp(2)-H)-trifluoromethylation of hydrazones would give access to the alpha-trifluoromethylated hydrazones that can serve as intermediates in the synthesis of pharmaceutically interesting fluorinated compounds. Herein, we demonstrate the Cu-catalyzed C(sp(2)-H)-trifluoromethylation of the aldehyde hydrazones using the readily available and cost effective Langlois reagent (sodium trifluoromethanesulfinate). This reaction is broadly applicable to a series of aromatic aldehyde N-aminomorpholine hydrazones to give the corresponding C(sp(2))-trifluoromethyl hydrazones in moderate to high yields. The reaction generally tolerates a series of electron-releasing as well as electron-withdrawing substituents on the aromatic ring.

About 4-Methoxybenzaldehyde, If you have any questions, you can contact Mehta, J; Aryal, P; Reddy, VP or concate me.. Category: indole-building-block

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Product Details of 123-11-5. Authors Kargar, S; Elhamifar, D; Zarnegaryan, A in ELSEVIER published article about in [Kargar, Shiva; Elhamifar, Dawood; Zarnegaryan, Ali] Univ Yasuj, Dept Chem, Yasuj 7591874831, Iran in 2021, Cited 83. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

A novel ionic liquid modified graphene oxide supported Mo-complex [GO@IL/MoO2(acae)(2)] was successfully prepared, characterized and its catalytic application was investigated. The GO@IL/MoO2(acae)(2) catalyst was prepared through the surface modification of graphene oxide with alkyl imidazolium chloride followed by treatment with molybdenyl acetylacetonate. The GO@IL/MoO2(acae)(2) catalyst was characterized by using FT-IR, PXRD, TGA, EDX, and SEM analyses. This catalyst showed high activity in the green production of pyrazolo[b] phthalazine dione derivatives under ultrasonic conditions. The designed catalyst was effectively recovered and successfully reused at least eight times without significant loss in its efficiency.

Product Details of 123-11-5. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Kargar, S; Elhamifar, D; Zarnegaryan, A or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Heteroleptic copper(I) complexes as energy transfer photocatalysts for the intermolecular [2+2] photodimerization of chalcones, cinnamates and cinnamamides WOS:000650994000030 published article about CYCLOBUTANE; CYCLOADDITION; PHOTOCYCLOADDITION; DERIVATIVES; REDUCTION; FLOW in [Wu, Qing-An; Ren, Chen-Chao; Chen, Feng; Wang, Tian-Qi; Zhang, Yu; Luo, Shu-Ping] Zhejiang Univ Technol, State Key Lab Breeding Base Green Chem Synth Tech, Chaowang Rd 18, Hangzhou 310014, Peoples R China; [Liu, Xue-Fen] Hangzhou Normal Univ, Qianjiang Coll, Hangzhou 310006, Peoples R China; [Chen, Jian-Bin] Qilu Univ Technol, Sch Chem & Chem Engn, Shandong Prov Key Lab Mol Engn, Shandong Acad Sci, Jinan 250353, Peoples R China in 2021.0, Cited 41.0. Formula: C8H8O2. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

The [2 + 2] photodimerization of chalcones, cinnamates and cinnamamides can be effectively catalyzed by heteroleptic copper(I) complexes. The reactions were carried out under mild reaction conditions and the products were obtained in 20-72% yield under visible light irradiation. The copper-based photocatalyst comprised of the rigid phenanthroline ligand with substituents at the 2,9-positions and the 4,7-positions showed high activity in the photodimerization via an energy transfer pathway. (C) 2021 Elsevier Ltd. All rights reserved.

About 4-Methoxybenzaldehyde, If you have any questions, you can contact Wu, QA; Ren, CC; Chen, F; Wang, TQ; Zhang, Y; Liu, XF; Chen, JB; Luo, SP or concate me.. Formula: C8H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Rao, RN; Chanda, K in ROYAL SOC CHEMISTRY published article about in [Rao, Ramdas Nishanth; Chanda, Kaushik] Vellore Inst Technol, Sch Adv Sci, Dept Chem, Vellore 632014, Tamil Nadu, India in 2021, Cited 30. Computed Properties of C8H8O2. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

An expeditious microwave assisted one-pot sequential route to synthesize pyrido fused imidazo[4,5-c]quinolines via the Pictet-Spengler cyclization strategy has been developed. In this study, substituted 2-amino pyridines are condensed with 2-bromo-2 ‘-nitroacetophenone to generate imidazo[1,2-a]pyridines with nitro group functionality at C-2 position. Reduction of nitro group to its amine congener in green media followed by the Pictet-Spengler cyclization strategy with substituted aldehydes led to the formation of new C-C and C-N bonds in a one-pot sequential manner. The cyclization proceeds through the CO(carbonyl)-C(H) cleavage of the aldehyde group via oxidative cross-coupling, transamination, cyclization and aromatization steps. Low cost reagents and a green solvent were used to facilitate the architecturally beautiful pyrido fused imidazo[4,5-c]quinoline scaffolds in high yields. The key features of this synthetic protocol are the use of microwave-assisted mild reaction conditions, one-pot sequential pathway, broad substrate scope and green media, which make it feasible for the synthesis of fused polyheterocycles. Moreover, the synthetic manipulation proceeded well with heteroaromatic and aliphatic aldehydes also in good yields.

Computed Properties of C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Rao, RN; Chanda, K or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Category: indole-building-block. In 2021 ORG BIOMOL CHEM published article about ASSISTED ONE-POT; MULTICOMPONENT SYNTHESIS; ULTRASOUND; WATER; NANOPARTICLES; DERIVATIVES; SCAFFOLDS; CHEMISTRY; PYRAZOLE; DESIGN in [Nazeri, Mohammad Taghi; Shaabani, Ahmad; Notash, Behrouz] Shahid Beheshti Univ, Fac Chem, GC, POB 19396-4716, Tehran, Iran; [Shaabani, Ahmad] RUDN Univ, Peoples Friendship Univ Russia, 6 Miklukho Maklaya St, Moscow 117198, Russia in 2021, Cited 74. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

Small-ring heterocycles comprising pyrrole and pyrazole are well known for their rich biological properties. In this article, an efficient green sonochemical approach was designed for the synthesis of novel, fully substituted pyrroles connected to pyrazole scaffolds via a one-pot, four-component isocyanide-based sequential reaction. This reaction was carried out using various 5-amino-pyrazoles, aldehydes, dialkyl acetylenedicarboxylates and isocyanides for the synthesis of fully functionalized pyrroles with high chemoselectivity in the presence of a catalytic amount of PTSA center dot H2O, in good to excellent yields under ultrasound irradiation. This waste-free (-H2O) reaction exhibited a high atom economy and step economy via creating four new bonds, including two C-N and two C-C bonds, and the formation of two five-member heterocycles which are connected in a single operation. The mechanism of this four-component domino process involved sequential imination-dipolar cyclization-[1,5]-H shift reactions. The synthesized compounds possess interesting fluorescence features, and the bioactive scaffolds might attract great interest in the fields of clinical diagnostics and biomedical research in the future.

Category: indole-building-block. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Nazeri, MT; Shaabani, A; Notash, B or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about NONFERROUS METALS; CARBON-STEEL; M HCL; ADSORPTION; BEHAVIOR; COMPOUND; DFT, Saw an article supported by the AICTE, New Delhi; TEQIP-II of VSSUT, Burla, India. Published in ELSEVIER in AMSTERDAM ,Authors: Upadhyay, A; Purohit, AK; Mahakur, G; Dash, S; Kar, PK. The CAS is 123-11-5. Through research, I have a further understanding and discovery of 4-Methoxybenzaldehyde. Formula: C8H8O2

Corrosion inhibition of mild steel (MS) by a series of 4-aminoantipyrine-based Schiff base has been studied in 1 N HCl aqueous medium adopting electrochemical method at different concentration (10(-2)-10(-5) M) and temperature (303-333 K). All of the inhibitors were found to be dominated by cathodic/anodic in nature (mixed type). Electrochemical impedence and polarization studies were in agreement with each other. The surface morphology (smoothness and roughness) was characterized by SEM, which indicates the formation of protective layer on the MS surface. The substituents on the Schiff bases influence their corrosion inhibition properties. Schiff bases having -OCH3, -OH and -NMe2 substituents exhibit more inhibition tendency as compared to other substituents. The role of cross conjugation in electron donating as well as accepting properties by heteroatom (N, O) and pi-electrons in corrosion inhibition was clearly observed from DFT calculations. Monolayer formation on the MS surface has been confirmed from the Langmuir isotherm fitting. Thermodynamic modeling has been done to understand the nature of adsorption. The values of Delta G (>-30 kJ/mol/K) indicate the existence of both physical and chemical interactions between the Schiff base molecules and metal surface. (C) 2021 Elsevier B.V. All rights reserved.

Formula: C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Upadhyay, A; Purohit, AK; Mahakur, G; Dash, S; Kar, PK or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Effects of anise, clove and thyme essential oils supplementation on rumen fermentation, blood metabolites, milk yield and milk composition in lactating goats WOS:000612162700024 published article about VITRO GAS-PRODUCTION; BERRY ESSENTIAL OILS; RUMINAL FERMENTATION; NUTRIENT DIGESTIBILITY; MICROBIAL FERMENTATION; GROWTH-PERFORMANCE; CONTINUOUS-CULTURE; DAIRY-COWS; METHANE EMISSION; LIPID-SYNTHESIS in [El-Essawy, Abeer M.; Abdel-Wahed, A. M.; Abdou, Ahlam R.] Desert Res Ctr, Anim & Poultry Nutr Dept, Cairo 11753, Egypt; [Anele, U. Y.] North Carolina Agr & Tech State Univ, Greensboro, NC 27411 USA; [Khattab, I. M.] Matrouh Univ, Fac Desert & Environm Agr, Dept Anim & Fish Prod, Matrouh 51744, Egypt in 2021.0, Cited 76.0. Category: indole-building-block. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

The present study evaluated the effects of essential oil (EO) from anise (AO), clove (CO) and thyme (TO) on the performance of lactating Shame goats. Eight lactating Shame goats with average body weight 34.90 +/- 0.9 kg and 3 years old were randomly assigned to four treatments in a duplicated 4 x 4 Latin square design, with four periods of 22 days. In each period, the goats were adapted to the treatments for 15 days and the remaining 7 days was used for sample collection. Goats were fed a basal diet without supplementation (control) or supplemented with anise (AO), thyme (TO) or clove (CO) at a daily dose of 2 mL/head/d. Feed intake was not affected by EO supplementations. Digestibility of organic matter, ether extract and acid detergent fibre was higher (P < 0.05) with EO supplementations when compared with the control. Supplementations of EO had no effect on milk (g/d) yield, protein and lactose, as well as the composition (g/kg) of protein and lactose. Fat yield (g/d) and fat content (g/kg) were greater (P < 0.05) in EO supplemented goats versus those on the control diet. Compared with control, ruminal ammonia-N was not affected whereas, ruminal pH was increased (P = 0.02) with EO supplementations. Rumen total volatile fatty acid concentration and molar proportion of acetate (C2) were higher (P < 0.05) in goats fed CO and TO compared to control, whereas propionate (C3) and butyrate (C4) and C2:C3 proportions were unchanged with EO inclusion. With the exception of a decrease (P = 0.05) in blood urea nitrogen (BUN) with EO supplementations, other blood parameters were not affected. Milk C8 and C12 fatty acids (FA) were lower (P < 0.05) with EO supplementations compared with control. Composition of unsaturated and monounsaturated FA was higher (P < 0.05) and polyunsaturated FA was decreased (P < 0.05) with EO supplementations compared with control. Proportions of C18:1 n-9 C18:3 n-3 and n-3 FA were increased (P < 0.05) and proportions of C18:3 n-6 C20:4 n-6 and n-6 FA were decreased (P < 0.05) in goats fed EO compared to the control group. Overall, all three EOs tested in this study had beneficial effects on digestion, rumen fermentation parameters and milk composition including milk FA profile. Supplementation of CO and TO tended to increase PUFA concentration in the milk which supports their recommendation in the diet of lactating ruminants. Category: indole-building-block. About 4-Methoxybenzaldehyde, If you have any questions, you can contact El-Essawy, AM; Anele, UY; Abdel-Wahed, AM; Abdou, AR; Khattab, IM or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In 2021 ACS CATAL published article about NITROGEN-HETEROCYCLES; ELECTRONIC-STRUCTURES; COMPLEXES; OXIDATION; HYDROGENATION; REACTIVITY in [Das, Siuli; Mondal, Rakesh; Chakraborty, Gargi; Guin, Amit Kumar; Paul, Nanda D.] Indian Inst Engn Sci & Technol, Dept Chem, Howrah 711103, India; [Das, Abhishek] Indian Assoc Cultivat Sci, Sch Chem Sci, Kolkata 700032, India in 2021, Cited 79. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5. Category: indole-building-block

Herein we report an exclusively ligand-centered redox controlled approach for the dehydrogenation of a variety of N-heterocycles using a Zn(II)-stabilized azo-anion radical complex as the catalyst. A simple, easy-to-prepare, and bench-stable Zn(II)-complex (1b) featuring the tridentate arylazo pincer, 2-((4-chlorophenyl)diazenyl)-1,10-phenanthroline, in the presence of zinc-dust, undergoes reduction to form the azo-anion radical species [1b]which efficiently dehydrogenates various saturated N-heterocycles such as 1,2,3,4-tetrahydro-2-methylquinoline, 1,2,3,4-tetrahydro-isoquinoline, indoline, 2-phenyl-2,3-dihydro-1H-benzoimidazole, 2,3-dihydro-2-phenylquinazolin-4(1H)-one, and 1,2,3,4-tetrahydro-2-phenylquinazolines, among others, under air. The catalyst has further been found to be compatible with the cascade synthesis of these N-heterocycles via dehydrogenative coupling of alcohols with other suitable coupling partners under air. Mechanistic investigation reveals that the dehydrogenation reactions proceed via a one-electron hydrogen atom transfer (HAT) pathway where the zinc-stabilized azo-anion radical ligand abstracts the hydrogen atom from the organic substrate(s), and the whole catalytic cycle proceeds via the exclusive involvement of the ligand-centered redox events where the zinc acts only as the template.

Category: indole-building-block. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Das, S; Mondal, R; Chakraborty, G; Guin, AK; Das, A; Paul, ND or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Computed Properties of C8H8O2. Authors Kratky, M; Svrckova, K; Vu, QA; Stepankova, S; Vinsova, J in MDPI published article about in [Kratky, Martin; Vu, Quynh Anh; Vinsova, Jarmila] Charles Univ Prague, Dept Organ & Bioorgan Chem, Fac Pharm Hradec Kralove, Akad Heyrovskeho 1203, Hradec Kralove 50005, Czech Republic; [Svrckova, Katarina; Stepankova, Sarka] Univ Pardubice, Fac Chem Technol, Dept Biol & Biochem Sci, Studentska 573, Pardubice 53210, Czech Republic in 2021, Cited 31. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

Based on the broad spectrum of biological activity of hydrazide-hydrazones, trifluoromethyl compounds, and clinical usage of cholinesterase inhibitors, we investigated hydrazones obtained from 4-(trifluoromethyl)benzohydrazide and various benzaldehydes or aliphatic ketones as potential inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). They were evaluated using Ellman’s spectrophotometric method. The hydrazide-hydrazones produced a dual inhibition of both cholinesterase enzymes with IC50 values of 46.8-137.7 mu M and 19.1-881.1 mu M for AChE and BuChE, respectively. The majority of the compounds were stronger inhibitors of AChE; four of them (2-bromobenzaldehyde, 3-(trifluoromethyl)benzaldehyde, cyclohexanone, and camphor-based 2o, 2p, 3c, and 3d, respectively) produced a balanced inhibition of the enzymes and only 2-chloro/trifluoromethyl benzylidene derivatives 2d and 2q were found to be more potent inhibitors of BuChE. 4-(Trifluoromethyl)-N’-[4-(trifluoromethyl)benzylidene]benzohydrazide 2l produced the strongest inhibition of AChE via mixed-type inhibition determined experimentally. Structure-activity relationships were identified. The compounds fit physicochemical space for targeting central nervous systems with no apparent cytotoxicity for eukaryotic cell line together. The study provides new insights into this CF3-hydrazide-hydrazone scaffold.

Computed Properties of C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Kratky, M; Svrckova, K; Vu, QA; Stepankova, S; Vinsova, J or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles