Category: 150-19-6

An article Single-step benzene hydroxylation by cobalt(ii) catalysts via a cobalt(iii)-hydroperoxo intermediate WOS:000530288800020 published article about LIQUID-PHASE HYDROXYLATION; HYDROGEN-PEROXIDE; HYDROPEROXO COMPLEX; DONOR LIGANDS; PHENOL; OXIDATION; REACTIVITY; OXYGENATION; ACTIVATION; MECHANISM in [Anandababu, Karunanithi; Muthuramalingam, Sethuraman; Mayilmurugan, Ramasamy] Madurai Kamaraj Univ, Sch Chem, Bioinorgan Chem Lab Phys Chem, Madurai 625021, Tamil Nadu, India; [Velusamy, Marappan] North Eastern Hill Univ, Dept Chem, Shillong 793022, Meghalaya, India in 2020.0, Cited 46.0. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6. SDS of cas: 150-19-6

The cobalt(ii) complexes of 4N tetradentate ligands have been synthesized and characterized as the catalysts for phenol synthesis in a single step. The molecular structure of the complexes showed a geometry in between square pyramidal and trigonal bipyramidal (tau, 0.49-0.88) with Co-N-amine and Co-N-Py bond distances of 2.104-2.254 angstrom and 2.043-2.099 angstrom, respectively. The complexes exhibited a Co2+/Co3+ redox potential around 0.489-0.500 V vs. Ag/Ag+ in acetonitrile. The complexes catalyzed hydroxylation of benzene using H2O2 (30%) and afforded phenol selectively as the major product. A maximum yield of phenol up to 29% and turnover number (TON) of 286 at 60 degrees C, and a yield of 19% and TON of 191 at 25 degrees C are achieved. This is the highest catalytic performance reported using cobalt(ii) complexes as catalysts to date. This aromatic hydroxylation presumably proceeded via a cobalt(iii)-hydroperoxo species, which was characterized by ESI-MS, and vibrational and electronic spectral methods. The formation of key intermediate [(L)Co-III(OOH)](2+) was accompanied by the appearance of the characteristic O -> Co(iii) ligand to metal charge transfer (LMCT) transition around 488-686 nm and vibration modes at 832 cm(-1) (O-OH) and 564 cm(-1) (Co-O). The geometry of one of the catalytically active intermediates was optimized by DFT and its spectral properties were calculated by TD-DFT calculations. These data are comparable to the experimental observations. The kinetic isotope effect (KIE) values (0.98-1.07) support the involvement of cobalt-bound oxygen species as a key intermediate. Isotope-labeling experiments using (H2O2)-O-18 showed an 89% incorporation of O-18, revealing that H2O2 is the main oxygen supplier for phenol formation from benzene. The catalytic efficiencies of cobalt complexes are tuned by ligand architectures via their geometrical configurations and steric properties.

SDS of cas: 150-19-6. About m-Methoxyphenol, If you have any questions, you can contact Anandababu, K; Muthuramalingam, S; Velusamy, M; Mayilmurugan, R or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Aota, Y; Doko, Y; Kano, T; Maruoka, K in WILEY-V C H VERLAG GMBH published article about TRANSITION-METAL-FREE; ASYMMETRIC-SYNTHESIS; ENANTIOSELECTIVE CONSTRUCTION; FLUORINATED ALCOHOLS; CROSS-COUPLINGS; CYCLOADDITION REACTIONS; PRIVILEGED STRUCTURES; NAZAROV CYCLIZATION; QUATERNARY CENTER; NATURAL-PRODUCTS in [Aota, Yusuke; Doko, Yuki; Kano, Taichi; Maruoka, Keiji] Kyoto Univ, Grad Sch Sci, Dept Chem, Sakyo Ku, Kyoto 6068502, Japan; [Maruoka, Keiji] Kyoto Univ, Grad Sch Pharmaceut Sci, Sakyo Ku, Kyoto 6068501, Japan; [Maruoka, Keiji] Guangdong Univ Technol, Sch Chem Engn & Light Ind, Guangzhou 510006, Peoples R China in 2020, Cited 164. SDS of cas: 150-19-6. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6

Nucleophilic addition to the oxy-allyl cation intermediate has emerged as a promising methodology for functionalization of the alpha-position of carbonyl compounds in an umpolung fashion. However, a structure of available carbon nucleophiles to trap the catalytically generated oxy-allyl cation has been limited to highly nucleophilic ones. Herein, we report the Bronsted acid-catalyzed alpha-arylation of ketones employing less explored phenolic nucleophiles as carbon nucleophiles in the oxy-allyl cation catalysis, affording ketones bearing an all carbon quaternary center at the alpha-position.

SDS of cas: 150-19-6. About m-Methoxyphenol, If you have any questions, you can contact Aota, Y; Doko, Y; Kano, T; Maruoka, K or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Synthesis of Novel 6-Aryloxy-4-chloro-2-phenylpyrimidines as Fungicides and Herbicide Safeners WOS:000575417400054 published article about ANTIFUNGAL ACTIVITY; DESIGN; PYRIMETHANIL; DERIVATIVES; INHIBITOR in [Deng, Xile; Zheng, Wenna; Jin, Can; Bai, Lianyang] Hunan Acad Agr Sci, Hunan Agr Biotechnol Res Inst, Key Lab Biol & Control Weeds, Changsha 410125, Peoples R China in 2020, Cited 68. Recommanded Product: m-Methoxyphenol. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6

Fenclorim is a commercial herbicide safener with fungicidal activity used for chloroacetanilide herbicides, which might be suitable as a lead compound for screening novel fungicides. However, little has been reported so far on the structure-activity relationship of fungicidal activities of fenclorim or its analogues. Here, a series of 4-chloro-6-substituted phenoxy-2-phenylpyrimidine derivatives was synthesized by a substructure splicing route using fenclorim as a lead compound. The structures of synthesized derivatives were characterized by H-1 NMR, C-13 NMR, and HRMS. Their fungicidal and herbicide safening activities were then evaluated. The results revealed that compound 11 had the best fungicidal activity against Sclerotinia sclerotiorum and Thanatephorus cucumeris, which was better than that of the control pyrimethanil. Moreover, compounds 3, 5, and 25 exhibited excellent safening activities against fresh weight, plant height, and root length, respectively. Such activities were significantly improved when compared to fenclorim. In summary, these findings look promising for the preparation of new fungicides and herbicide safeners based on the structure of fenclorim.

Recommanded Product: m-Methoxyphenol. About m-Methoxyphenol, If you have any questions, you can contact Deng, XL; Zheng, WN; Jin, C; Bai, LY or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Hydrodeoxygenation of Guaiacol to Phenol over Ceria-Supported Iron Catalysts WOS:000608850500023 published article about VAPOR-PHASE HYDRODEOXYGENATION; TOTAL-ENERGY CALCULATIONS; MODEL COMPOUNDS; SELECTIVE HYDRODEOXYGENATION; MOSSBAUER-SPECTROSCOPY; FE CATALYSTS; BIO-OIL; LIGNIN; REDUCTION; HYDROGENATION in [Li, Congcong; Nakagawa, Yoshinao; Tomishige, Keiichi] Tohoku Univ, Sch Engn, Dept Appl Chem, Sendai, Miyagi 9808579, Japan; [Tamura, Masazumi] Osaka City Univ, Adv Res Inst Nat Sci & Technol, Res Ctr Artificial Photosynth, Osaka 5588585, Japan; [Nakayama, Akira] Univ Tokyo, Grad Sch Engn, Dept Chem Syst Engn, Tokyo 1138656, Japan; [Nakagawa, Yoshinao; Tomishige, Keiichi] Tohoku Univ, Res Ctr Rare Met & Green Innovat, Sendai, Miyagi 9808579, Japan in 2020.0, Cited 82.0. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6. Computed Properties of C7H8O2

Guaiacol, one of the main components and a model compound of lignin-derived bio-oil, was transformed into phenol and methylated phenols over a series of supported iron catalysts under atmospheric pressure. CeO2 support was superior to other conventional supports in view of the activity of supported iron catalysts. The effect of iron loading amount on CeO2 supports showed a linear relationship with an iron loading amount up to 3 wt %, which corresponded to monolayer coverage, and then it was almost constant with a further increase of the iron content. The Fe/CeO2 catalyst with 3 wt % iron loading (Fe(3)/CeO2) had higher stability than the catalysts with higher iron loadings. The optimal Fe(3)/CeO2 catalyst showed a 56% phenol yield and an 87% sum yield of phenol and methylated phenols at 673 K under guaiacol/N-2/H-2 = 1/45/135 flow with W/F = 1.0 g.h.mol(total)(-1). The X-ray diffraction (XRD), diffuse reflectance UV-visible (DRUV-vis), Raman, and X-ray absorption spectroscopy (XAS) characterizations confirmed that the FeOx species were finely dispersed on the Fe/CeO2 catalyst with <= 3 wt % iron, and higher iron loadings led to formation of Fe2O3 particles in calcined catalysts. Although other supported iron catalysts with 3 wt % iron loading also contained dispersed FeOx species, the reducibility of Fe/CeO2 was higher than that of other supported iron catalysts, which might be related to the higher activity. The XAS characterization of spent catalysts showed that the stable Fe(3)/CeO2 catalyst contained only Fe3+ and Fe2+ species during the reaction, while in the Fe(10)/CeO2 catalyst, the reduction of iron proceeded to a greater extent and Fe3C crystals grew during the reaction. The structure of this monolayer Fe(3)/CeO2 was further characterized by extended X-ray absorption fine structure (EXAFS) and density functional theory (DFT) calculations. Rather than a two-dimensional Fe oxide sheet, a structure composed of dispersed Fe4O6 clusters is suggested for monolayer coverage. The coordinatively unsaturated site (CUS) in the interface between FeOx and reducible CeO2 is suggested to be the active site. Computed Properties of C7H8O2. About m-Methoxyphenol, If you have any questions, you can contact Li, CC; Nakagawa, Y; Tamura, M; Nakayama, A; Tomishige, K or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about SOLVENT-FREE SYNTHESIS; SOLID SULFONIC-ACID; DERIVATIVES; EFFICIENT; SBA-15; DESIGN, Saw an article supported by the Consejo Nacional de Ciencia y Tecnologia in MexicoConsejo Nacional de Ciencia y Tecnologia (CONACyT) [364826]. Published in ELSEVIER in AMSTERDAM ,Authors: Gonzalez-Carrillo, G; Gonzalez, J; Emparan-Legaspi, MJ; Lino-Lopez, GJ; Aguayo-Villarreal, IA; Ceballos-Magana, SG; Martinez-Martinez, FJ; Muniz-Valencia, R. The CAS is 150-19-6. Through research, I have a further understanding and discovery of m-Methoxyphenol. Recommanded Product: m-Methoxyphenol

Coumarins and their synthetic derivatives are extensively used as base chemicals in diverse industrial applications in the fields of pharmaceutics, cosmetics, and agrochemicals, among others. Due to the growing number of applications, the need for new methods of coumarins synthesis has gained importance worldwide. In this sense, the use of propylsulfonic acid supported in FDU-5 (FDU-5-Pr-SO3H) as a catalyst for the synthesis of coumarins via Pechmann condensation in solvent free medium was investigated. FDU-5-Pr-SO3H was synthesized by co-condensation of MPTES and TEOS. FDU-5-Pr-SO3H was used as catalyst for the synthesis of 7-hydroxy-4-methylcoumarin and reaction conditions were optimized. The optimization process involved the study of the influence of the catalyst load, Resorcinol:EAA molar ratio, reaction temperature and reaction time. The optimal conditions were: catalyst load of 1.65 mol %, reactants molar ratio of 1:1.5, temperature 130 degrees C and 60 min of reaction time. Under these conditions, the FDU-5-Pr-SO3H material showed excellent yield (96.5%) and turn over frequency (59 h(-1)). Finally, the synthetized material was assessed as a catalyst with other phenolic compounds with ethyl acetoacetate and with ethyl benzoylacetate. The obtained products were isolated and identified by comparison of their spectral data with those reported in literature; from these results can be concluded that the catalyst is active with a wide range of phenolic substrates.

About m-Methoxyphenol, If you have any questions, you can contact Gonzalez-Carrillo, G; Gonzalez, J; Emparan-Legaspi, MJ; Lino-Lopez, GJ; Aguayo-Villarreal, IA; Ceballos-Magana, SG; Martinez-Martinez, FJ; Muniz-Valencia, R or concate me.. Recommanded Product: m-Methoxyphenol

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about TRANSITION-METAL-FREE; ASYMMETRIC-SYNTHESIS; ENANTIOSELECTIVE CONSTRUCTION; FLUORINATED ALCOHOLS; CROSS-COUPLINGS; CYCLOADDITION REACTIONS; PRIVILEGED STRUCTURES; NAZAROV CYCLIZATION; QUATERNARY CENTER; NATURAL-PRODUCTS, Saw an article supported by the . Product Details of 150-19-6. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Aota, Y; Doko, Y; Kano, T; Maruoka, K. The CAS is 150-19-6. Through research, I have a further understanding and discovery of m-Methoxyphenol

Nucleophilic addition to the oxy-allyl cation intermediate has emerged as a promising methodology for functionalization of the alpha-position of carbonyl compounds in an umpolung fashion. However, a structure of available carbon nucleophiles to trap the catalytically generated oxy-allyl cation has been limited to highly nucleophilic ones. Herein, we report the Bronsted acid-catalyzed alpha-arylation of ketones employing less explored phenolic nucleophiles as carbon nucleophiles in the oxy-allyl cation catalysis, affording ketones bearing an all carbon quaternary center at the alpha-position.

About m-Methoxyphenol, If you have any questions, you can contact Aota, Y; Doko, Y; Kano, T; Maruoka, K or concate me.. Product Details of 150-19-6

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

COA of Formula: C7H8O2. Recently I am researching about NITROALKENES; ALKYLATION; INDOLES; IONS; NAPHTHOLS; COMPLEX; ETHERS, Saw an article supported by the National Science FoundationNational Science Foundation (NSF) [CHE-0847358, CHE-1363375]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Mesa, KM; Hibbard, HA; Franz, AK. The CAS is 150-19-6. Through research, I have a further understanding and discovery of m-Methoxyphenol

Sodium tetrakis[3,5-bis(trifluoromethyl)-phenyl]borate (NaBArF) demonstrates catalytic activity for Friedel-Crafts addition reactions of phenolic and other aromatic nucleophiles to trans-beta-nitrostyrene. Solubility studies demonstrate a chelating effect between the Na+ cation and the nitro group of trans-beta-nitrostyrene as the basis for catalytic activation. Mechanistic studies are presented, including a comparison with other sodium salts, additive effects, and reaction progress kinetics analysis using F-19 NMR spectroscopy.

COA of Formula: C7H8O2. About m-Methoxyphenol, If you have any questions, you can contact Mesa, KM; Hibbard, HA; Franz, AK or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Saka, ET; Kahriman, N in ELSEVIER SCIENCE SA published article about THIN-FILMS; COBALT PHTHALOCYANINE; ZINC PHTHALOCYANINE; CYCLOHEXENE OXIDATION; SELECTIVE OXIDATION; SUBSTITUTED CO(II); FE(II); 2,6-DI-TERT-BUTYLPHENOL; AUTOXIDATION; DEGRADATION in [Saka, Ece Tugba; Kahriman, Nuran] Karadeniz Tech Univ, Fac Sci, Dept Chem, TR-61080 Trabzon, Turkey in 2019.0, Cited 43.0. Application In Synthesis of m-Methoxyphenol. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6

Phenols from various man-made activities pose threats to public health and aquatic ecosystems. A number of technologies (e.g., adsorption, oxidation, and biological methods) have been proposed and tested to remove phenolic compounds from different sources. Among these technologies, oxidation process is considered one of the most efficient tools for abating phenolic compounds because of low cost, easy scalability, and ecofriendly production. In this work, we aim to synthesize and characterize potential catalysts (Co(II) and Cu(II) phthalocyanines 6 and 7) for phenolic compounds oxidation. Different parameters influenced the oxidation process were determined and phenolic compounds oxidize to the less harmful products with high conversion and yield in the presence of Co(II) and Cu(II) phthalocyanine catalysts. (c) 2019 Elsevier B.V. All rights reserved.

Application In Synthesis of m-Methoxyphenol. About m-Methoxyphenol, If you have any questions, you can contact Saka, ET; Kahriman, N or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

I found the field of Chemistry; Science & Technology – Other Topics; Materials Science; Physics very interesting. Saw the article Synthesis of Polystyrene-Based Cationic Nanomaterials with Pro-Oxidant Cytotoxic Activity on Etoposide-Resistant Neuroblastoma Cells published in 2021.0. Safety of m-Methoxyphenol, Reprint Addresses Alfei, S (corresponding author), Univ Genoa, Dept Pharm, Viale Cembrano, I-16148 Genoa, Italy.. The CAS is 150-19-6. Through research, I have a further understanding and discovery of m-Methoxyphenol

Drug resistance is a multifactorial phenomenon that limits the action of antibiotics and chemotherapeutics. Therefore, it is essential to develop new therapeutic strategies capable of inducing cytotoxic effects circumventing chemoresistance. In this regard, the employment of natural and synthetic cationic peptides and polymers has given satisfactory results both in microbiology, as antibacterial agents, but also in the oncological field, resulting in effective treatment against several tumors, including neuroblastoma (NB). To this end, two polystyrene-based copolymers (P5, P7), containing primary ammonium groups, were herein synthetized and tested on etoposide-sensitive (HTLA-230) and etoposide-resistant (HTLA-ER) NB cells. Both copolymers were water-soluble and showed a positive surface charge due to nitrogen atoms, which resulted in protonation in the whole physiological pH range. Furthermore, P5 and P7 exhibited stability in solution, excellent buffer capacity, and nanosized particles, and they were able to reduce NB cell viability in a concentration-dependent way. Interestingly, a significant increase in reactive oxygen species (ROS) production was observed in both NB cell populations treated with P5 or P7, establishing for both copolymers an unequivocal correlation between cytotoxicity and ROS generation. Therefore, P5 and P7 could be promising template macromolecules for the development of new chemotherapeutic agents able to fight NB chemoresistance.

Safety of m-Methoxyphenol. About m-Methoxyphenol, If you have any questions, you can contact Alfei, S; Marengo, B; Valenti, GE; Domenicotti, C or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 150-19-6. Authors Zhao, RN; Zhou, Z; Liu, JX; Wang, X; Zhang, Q; Li, D in AMER CHEMICAL SOC published article about in [Zhao, Ruinan; Zhou, Zhong; Liu, Jixiang; Wang, Xia; Zhang, Qian; Li, Dong] Hubei Univ Technol, Sch Mat & Chem Engn, Wuhan 430068, Peoples R China in 2020.0, Cited 77.0. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6

An efficient silver-catalyzed para-selective amination and aminative dearomatization of phenols with azodicarboxylates was developed. It afforded the para-aminophenols or amino cyclohexadieneones from free phenols depending on whether it has a para-substituent. The reaction proceeded smoothly in water under simple and mild conditions, giving the highly selective products in good yields within a short reaction time. It also showed broad substrate scope and good functional group compatibility.

About m-Methoxyphenol, If you have any questions, you can contact Zhao, RN; Zhou, Z; Liu, JX; Wang, X; Zhang, Q; Li, D or concate me.. SDS of cas: 150-19-6

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles