Category: 150-19-6

An article Synthesis of chiral alpha-substituted alpha-amino acid and amine derivatives through Ni-catalyzed asymmetric hydrogenation WOS:000532243000017 published article about SYNERGISTIC CU/PD CATALYSIS; ENANTIOSELECTIVE SYNTHESIS; AZOMETHINE YLIDES; 1,3-DIPOLAR CYCLOADDITION; ARYLBORONIC ACIDS; KETIMINE ESTERS; LIGANDS; ALKYLATION; AMINATION; ARYLATION in [Liu, Gongyi; Zhang, Xianghe; Cong, Hengjiang; Zhang, Xumu; Dong, Xiu-Qin] Wuhan Univ, Suzhou Inst, Coll Chem & Mol Sci,Minist Educ, Key Lab Biomed Polymers,Engn Res Ctr Organosilico, Wuhan 430072, Hubei, Peoples R China; [Wang, Heng; Zhang, Xumu] Southern Univ Sci & Technol, Dept Chem, Shenzhen Grubbs Inst, Shenzhen 518055, Guangdong, Peoples R China in 2020.0, Cited 91.0. Quality Control of m-Methoxyphenol. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6

Highly efficient Ni-catalyzed asymmetric hydrogenation of cyclic N-sulfonyl ketimino esters was, for the first time, successfully developed, providing various chiral alpha-monosubstituted alpha-amino acid derivatives with excellent results (97-99% yields, 90 to >99% ee). Cyclic N-sulfonyl ketimines were also hydrogenated well to afford chiral amine derivatives with 98-99% yields and 97 to >99% ee. The gram-scale asymmetric hydrogenation was performed well with 85% yield and 99% ee using only 0.2 mol% catalyst.

Quality Control of m-Methoxyphenol. About m-Methoxyphenol, If you have any questions, you can contact Liu, GY; Zhang, XH; Wang, H; Cong, HJ; Zhang, XM; Dong, XQ or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Computed Properties of C7H8O2. Catinella, G; Mattio, LM; Musso, L; Arioli, S; Mora, D; Beretta, GL; Zaffaroni, N; Pinto, A; Dallavalle, S in [Catinella, Giorgia; Mattio, Luce M.; Musso, Loana; Arioli, Stefania; Mora, Diego; Pinto, Andrea; Dallavalle, Sabrina] Univ Milan, Dept Food Environm & Nutr Sci DeFENS, Via Celoria 2, Milan 20133, Italy; [Beretta, Giovanni Luca; Zaffaroni, Nadia] Fdn IRCCS Ist Nazl Tumori, Dept Appl Res & Technol Dev, Mol Pharmacol Unit, Via Amadeo 42, Milan, Italy published Structural Requirements of Benzofuran Derivatives Dehydro-delta- and Dehydro-epsilon-Viniferin for Antimicrobial Activity Against the Foodborne Pathogen Listeria monocytogenes in 2020.0, Cited 24.0. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6.

In a recent study, we investigated the antimicrobial activity of a collection of resveratrol-derived monomers and dimers against a series of foodborne pathogens. Out of the tested molecules, dehydro-delta-viniferin and dehydro-epsilon-viniferin emerged as the most promising derivatives. To define the structural elements essential to the antimicrobial activity against the foodborne pathogen L. monocytogenes Scott A as a model Gram-positive microorganism, the synthesis of a series of simplified benzofuran-containing derivatives was carried out. The systematic removal of the aromatic moieties of the parent molecules allowed a deeper insight into the most relevant structural features affecting the activity. While the overall structure of compound 1 could not be altered without a substantial loss of antimicrobial activity, the structural simplification of compound 2 (minimal inhibitory concentration (MIC) 16 mu g/mL, minimal bactericidal concentration (MBC) >512 mu g/mL) led to the analogue 7 with increased activity (MIC 8 mu g/mL, MBC 64 mu g/mL).

Computed Properties of C7H8O2. About m-Methoxyphenol, If you have any questions, you can contact Catinella, G; Mattio, LM; Musso, L; Arioli, S; Mora, D; Beretta, GL; Zaffaroni, N; Pinto, A; Dallavalle, S or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Category: indole-building-block. In 2020 ORG CHEM FRONT published article about SUZUKI-MIYAURA; ALKYL-HALIDES; ASYMMETRIC 1,4-ADDITION; ADDRESSING CHALLENGES; OXIDATIVE ADDITION; GRIGNARD-REAGENTS; CHLORIDES; TOSYLATES; BROMIDES; SECONDARY in [Lee, Hang Wai; So, Chau Ming; Yuen, On Ying; Wong, Wing Tak; Kwong, Fuk Yee] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Kowloon, Hong Kong, Peoples R China; [Lee, Hang Wai; So, Chau Ming; Wong, Wing Tak] Hong Kong Polytech Univ, Shenzhen Res Inst SZRI, Shenzhen, Peoples R China; [Yuen, On Ying; Kwong, Fuk Yee] Chinese Univ Hong Kong, Dept Chem, Shatin, Peoples R China in 2020, Cited 72. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6.

The first palladium-catalyzed cross-coupling reaction of aryl/heteroaryl and alkenyl mesylates and tosylates with aryl titanium as the multi-functional reagent is reported. Using the catalyst system of Pd(OAc)(2) associated with the new NMe2-CM-Phos (L14), a broad range of electron-rich, electron-neutral, electron-deficient, and sterically hindered aryl/heteroaryl and alkenyl mesylates and tosylates are well coupled with aryl titanium reagents to give the corresponding products in good to excellent yields. The catalyst loading down to 0.2 mol% Pd and the reaction time shortening to 10 min can be achieved. The reaction can be easily scaled up to the gram scale without diminishing the product yield.

About m-Methoxyphenol, If you have any questions, you can contact Lee, HW; So, CM; Yuen, OY; Wong, WT; Kwong, FY or concate me.. Category: indole-building-block

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Xu, JC; Chen, JJ; Gao, F; Xie, SG; Xu, XH; Jin, Z; Yu, JQ in [Xu, Jiancong; Chen, Jingjing; Gao, Feng; Xie, Shuguang; Xu, Xiaohua; Jin, Zhong] Nankai Univ, Coll Chem, State Key Lab, Tianjin 300071, Peoples R China; [Xu, Jiancong; Chen, Jingjing; Gao, Feng; Xie, Shuguang; Xu, Xiaohua; Jin, Zhong] Nankai Univ, Coll Chem, Inst Elementoorgan Chem, Tianjin 300071, Peoples R China; [Xu, Xiaohua; Jin, Zhong] Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China; [Yu, Jin-Quan] Scripps Res Inst, Dept Chem, 10550 North Torrey Pines Rd, La Jolla, CA 92037 USA published Sequential Functionalization of meta-C-H and ipso-C-O Bonds of Phenols in 2019, Cited 48. COA of Formula: C7H8O2. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6.

The use of a template as a linchpin motif in directed remote C-H functionalization is a versatile yet relatively underexplored strategy. We have developed a template-directed approach to realizing one-pot sequential palladium-catalyzed meta-selective C-H olefination of phenols, and nickel-catalyzed ipso-C-O activation and arylation. Thus, this bifunctional template converts phenols to synthetically useful 1,3-disubstituted arenes.

About m-Methoxyphenol, If you have any questions, you can contact Xu, JC; Chen, JJ; Gao, F; Xie, SG; Xu, XH; Jin, Z; Yu, JQ or concate me.. COA of Formula: C7H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Redox-neutral photocatalytic strategy for selective C-C bond cleavage of lignin and lignin models via PCET process WOS:000497954900006 published article about PRIMARY ALCOHOL OXIDATION; VISIBLE-LIGHT; ORGANIC FRAMEWORKS; RADICAL CATIONS; CARBON-CARBON; DEPOLYMERIZATION; HYDROGENOLYSIS; TRANSFORMATION; DEGRADATION; BIOMASS in [Wang, Yinling; Liu, Yue; He, Jianghua; Zhang, Yuetao] Jilin Univ, Coll Chem, State Key Lab Supramol Struct & Mat, Changchun 130012, Jilin, Peoples R China in 2019, Cited 62. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6. Recommanded Product: m-Methoxyphenol

It remains challenging to achieve the selective cleavage of C-C bonds in lignin or lignin model compounds to produce aromatic products in high yield and selectivity. We have developed a redox-neutral photocatalytic strategy to accomplish this goal in both beta-O-4 and beta-1 lignin models at room temperature (RT) via proton-coupled electron transfer (PCET) process without any pretreatments of substrate, by adjusting the alkalinity of base to obtain a lignin models/base PCET pair with a bond dissociation free energy close to 102 kcal/mol. Without breaking down C-beta-C-gamma bond and any C-O bonds, this PCET method is 100% atom economy and produces exclusive C-alpha-C-beta bond cleavage products, such as benzaldehydes (up to 97%) and phenyl ethers (up to 96%), in high to excellent yields and selectivities. Preliminary studies indicated that the PCET strategy is also effective for the depolymerization of native lignin at RT, thus providing significantly important foundation to the depolymerization of lignin. (C) 2019 Science China Press. Published by Elsevier B.V. and Science China Press. All rights reserved.

Recommanded Product: m-Methoxyphenol. About m-Methoxyphenol, If you have any questions, you can contact Wang, YL; Liu, Y; He, JH; Zhang, YT or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about H BOND FUNCTIONALIZATION; FRIEDEL-CRAFTS REACTION; C-H; SYNTHETIC APPLICATIONS; ARYL; ALKYLATION; NAPHTHOLS; ACCESS; CHLORINATION; METHYLATION, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21971066, 21772042]; Science and Technology Commission of Shanghai MunicipalityScience & Technology Commission of Shanghai Municipality (STCSM) [18JC1412300]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Tang, ZQ; Li, DD; Yue, YD; Peng, D; Liu, L. The CAS is 150-19-6. Through research, I have a further understanding and discovery of m-Methoxyphenol. Recommanded Product: m-Methoxyphenol

We have developed a Bronsted acid catalysed highly ortho-selective functionalization of free phenols with readily available N,O-acetals under mild conditions, furnishing various corresponding aminomethylated phenol products in moderate to excellent yields. The salient features of this transformation include mild conditions, good substrate scope, excellent ortho-selectivity, high efficiency, and ease of further transformation.

About m-Methoxyphenol, If you have any questions, you can contact Tang, ZQ; Li, DD; Yue, YD; Peng, D; Liu, L or concate me.. Recommanded Product: m-Methoxyphenol

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Selective functionalisation of aromatic alcohols with supramolecularly regulated gold(i) catalysts WOS:000544472100005 published article about H BOND FUNCTIONALIZATION; ASYMMETRIC HYDROFORMYLATION; INSERTION; PHENOLS; LIGAND; APPROXIMATION; REACTIVITY; COMPLEXES; PRODUCTS; ORIGINS in [Carreras, Lucas; Vidal-Ferran, Anton] Inst Chem Res Catalonia ICIQ, Av Paisos Catalans 16, Tarragona 43007, Spain; [Franconetti, Antonio; Frontera, Antonio] Univ Illes Balears, Dept Quim, Crta Valldemossa Km 7-5, Palma De Mallorca 07122, Spain; [Grabulosa, Arnald; Vidal-Ferran, Anton] Univ Barcelona, Dept Inorgan & Organ Chem, Sect Inorgan Chem, Carrer Marti i Franques 1-11, Barcelona 08028, Spain; [Vidal-Ferran, Anton] ICREA, Pg Lluis Co 23, Barcelona 08010, Spain in 2020.0, Cited 64.0. Recommanded Product: 150-19-6. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6

Phosphite-based Au(i) catalytic systems containing an array of structurally diverse polyether-based regulation sites were designed and synthesised. These catalysts have been successfully tested in the Au(i)-catalysed C-H functionalisation of phenols and related derivatives with gold-carbenes derived from diazo compounds. Regulation of the steric congestion around the catalytic Au(i) centreviaion-dipole interactions with an external regulation agent led to an enhancement of both the activity and selectivity of the reaction. This new approach in supramolecular gold(i) catalysis has been applied to the derivatisation of an array of substituted phenols and related substrates and to the preparation of an advanced synthetic intermediate of the anticancer agent tamoxifen. The effects of the regulation agent on the selectivity and yield of the reaction have been studied and rationalised using DFT-D calculations.

About m-Methoxyphenol, If you have any questions, you can contact Carreras, L; Franconetti, A; Grabulosa, A; Frontera, A; Vidal-Ferran, A or concate me.. Recommanded Product: 150-19-6

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Pictet-Spengler condensations using 4-(2-aminoethyl)coumarins WOS:000558066500020 published article about RESISTANT PROSTATE-CANCER; ANDROGEN RECEPTOR; DIHYDROTESTOSTERONE; TARGET; INHIBITORS; ANDROSTANEDIOL; DEHYDROGENASES; IDENTIFICATION; TESTOSTERONE; BIOCHEMISTRY in [Sviripa, Vitaliy M.; Williams, Alexander H.; Zhan, Chang-Guo] Univ Kentucky, Coll Pharm, Dept Pharmaceut Sci, Lexington, KY 40536 USA; [Sviripa, Vitaliy M.; Begley, Kristin L.; Wyrebek, Przemyslaw; Kril, Liliia M.; Balia, Andrii G.; Zhan, Chang-Guo; Watt, David S.] Univ Kentucky, Coll Pharm, Ctr Pharmaceut Res & Innovat, Lexington, KY 40536 USA; [Sviripa, Vitaliy M.; Liu, Chunming; Watt, David S.] Univ Kentucky, Lucille Parker Markey Canc Ctr, Lexington, KY 40536 USA; [Fiandalo, Michael, V; Mohler, James L.] Roswell Pk Comprehens Canc Ctr, Dept Expt Therapeut, Buffalo, NY 14263 USA; [Begley, Kristin L.; Wyrebek, Przemyslaw; Kril, Liliia M.; Balia, Andrii G.; Liu, Chunming; Watt, David S.] Univ Kentucky, Coll Med, Dept Mol & Cellular Biochem, Lexington, KY 40536 USA; [Parkin, Sean R.] Univ Kentucky, Coll Arts & Sci, Dept Chem, Lexington, KY 40506 USA; [Subramanian, Vivekanandan] Univ Kentucky, Coll Pharm, NMR Ctr, Lexington, KY 40536 USA; [Chen, Xi] South Cent Univ Nationalities, Coll Chem & Mat Sci, Wuhan 430074, Peoples R China; [Mohler, James L.] Roswell Pk Comprehens Canc Ctr, Dept Urol, Buffalo, NY 14263 USA in 2020.0, Cited 57.0. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6. Product Details of 150-19-6

Androgen-deprivation therapy (ADT) is only a palliative measure, and prostate cancer invariably recurs in a lethal, castration-resistant form (CRPC). Prostate cancer resists ADT by metabolizing weak, adrenal androgens to growth-promoting 5 alpha-dihydrotestosterone (DHT), the preferred ligand for the androgen receptor (AR). Developing small-molecule inhibitors for the final steps in androgen metabolic pathways that utilize 17-oxidoreductases required probes that possess fluorescent groups at C-3 and intact, naturally occurring functionality at C-17. Application of the Pictet-Spengler condensation to substituted 4-(2-aminoethyl)coumarins and 5 alpha-androstane-3-ones furnished spirocyclic, fluorescent androgens at the desired C-3 position. Condensations required the presence of activating C-7 amino orN,N-dialkylamino groups in the 4-(2-aminoethyl)coumarin component of these condensation reactions. Successful Pictet-Spengler condensation, for example, of DHT with 9-(2-aminoethyl)-2,3,6,7-tetrahydro-1H,5H,11H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11-one led to a spirocyclic androgen, (3R,5S,10S,13S,17S)-17-hydroxy-10,13-dimethyl-1,2,2 ‘,3 ‘,4,5,6,7,8,8 ‘,9,9 ‘,10,11,12,12 ‘,13,13 ‘,14,15,16,17-docosahydro-7 ‘ H,11 ‘ H-spiro-[cyclopenta[a]phenanthrene-3,4 ‘-pyrido[3,2,1-ij]pyrido[4 ‘,3 ‘:4,5]pyrano[2,3-f]quinolin]-5 ‘(1 ‘ H)-one. Computational modeling supported the surrogacy of the C-3 fluorescent DHT analog as a tool to study 17-oxidoreductases for intracrine, androgen metabolism.

Product Details of 150-19-6. About m-Methoxyphenol, If you have any questions, you can contact Sviripa, VM; Fiandalo, MV; Begley, KL; Wyrebek, P; Kril, LM; Balia, AG; Parkin, SR; Subramanian, V; Chen, X; Williams, AH; Zhan, CG; Liu, CM; Mohler, JL; Watt, DS or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: m-Methoxyphenol. Recently I am researching about ASYMMETRIC CATALYSIS; SALEN, Saw an article supported by the . Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Lamb, KJ; Dowsett, MR; North, M; Parker, RR; Whitwood, AC. The CAS is 150-19-6. Through research, I have a further understanding and discovery of m-Methoxyphenol

The synthesis of novel tetrahydroquinoxalines by a metal induced one-electron reductive cyclisation of salophen ligands was found to occur when a salophen ligand was treated with chromium(ii) chloride or decamethylcobaltocene.

About m-Methoxyphenol, If you have any questions, you can contact Lamb, KJ; Dowsett, MR; North, M; Parker, RR; Whitwood, AC or concate me.. Recommanded Product: m-Methoxyphenol

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about ELECTROPHILIC DISPLACEMENT-REACTIONS; CATALYZED AEROBIC DEHYDROGENATION; HX-REDUCTIVE-ELIMINATION; CONJUGATE ADDITION; ANTIOXIDANT ACTIVITY; EFFICIENT SYNTHESIS; MOLECULAR-OXYGEN; HECK REACTION; FLAVONOIDS; KETONES, Saw an article supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) – Ministry of Science, ICT & Future Planning [NRF-2016R1A2B4015169]. Product Details of 150-19-6. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Yoo, HS; Son, SH; Cho, YY; Lee, SJ; Jang, HJ; Kim, YM; Kim, DH; Kim, NY; Park, BY; Lee, YS; Kim, NJ. The CAS is 150-19-6. Through research, I have a further understanding and discovery of m-Methoxyphenol

A total of 47 flavanones were expediently synthesized via one-pot beta-arylation of chromanones, a class of simple ketones possessing chemically unactivated beta sites, with arylboronic acids via tandem palladium(II) catalysis. This reaction provides a novel route to various flavanones, including natural products such as naringenin trimethyl ether, in yields up to 92%.

Product Details of 150-19-6. About m-Methoxyphenol, If you have any questions, you can contact Yoo, HS; Son, SH; Cho, YY; Lee, SJ; Jang, HJ; Kim, YM; Kim, DH; Kim, NY; Park, BY; Lee, YS; Kim, NJ or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles