Category: 150-76-5

An article Electrochemical phosphorylation of arenols and anilines leading to organophosphates and phosphoramidates WOS:000655187900001 published article about SECONDARY PHOSPHINE OXIDES; FLAME-RETARDANT; ESTERIFICATION; ALCOHOLS; AMINES; THIOLS in [Zhong, Zijian; Xu, Pan; Zhou, Aihua] Jiangsu Univ, Sch Pharm, Xuefu Rd 301, Zhenjiang 212013, Jiangsu, Peoples R China in 2021.0, Cited 36.0. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5. Product Details of 150-76-5

A practical phosphorylation for generating organophosphates and phosphoramidates via electrochemical dehydrogenative cross-coupling of P(O)H compounds with arenols and anilines is disclosed. This method involves using inorganic iodide salts as both redox catalysts and electrolytes in an undivided cell without the addition of oxidants or bases. A preliminary mechanistic study suggests that radicals are not involved in this process. This method is green and eco-friendly and has good functional group tolerance, high yields and broad substrate scope, with the potential for practical synthesis.

Product Details of 150-76-5. About Mequinol, If you have any questions, you can contact Zhong, ZJ; Xu, P; Zhou, AH or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In 2021 BIOORG MED CHEM LETT published article about ANTIINFLAMMATORY ACTIVITY; DERIVATIVES; COUMARIN; ANTICANCER; DESIGN; VITRO; ACID in [Nesaragi, Aravind R.; Kamble, Ravindra R.; Kodasi, Barnabas; Hoolageri, Swati R.; Bayannavar, Praveen K.] Karnatak Univ, Dept Studies Chem, Dharwad 580003, Karnataka, India; [Dixit, Shruti; Vootla, Shyamkumar] Karnatak Univ, Dept Biotechnol & Microbiol, Dharwad 580003, Karnataka, India; [Dasappa, Jagadeesh Prasad] Mangalore Univ, Dept Chem, Mangalagangothri 574199, Konaje, India; [Joshi, Shrinivas D.] SETs Coll Pharm, Dept Pharmaceut Chem, Novel Drug Design & Discovery Lab, Dharwad 580002, Karnataka, India; [Kumbar, Vijay M.] Maratha Mandals NGH Inst Dent Sci & Res Ctr, Cent Res Lab, Belagavi 590010, India in 2021, Cited 24. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5. HPLC of Formula: C7H8O2

A modest, competent and green synthetic procedure for novel coumarinyl-1,3,4-oxadiazolyl-2mercaptobenzoxazoles 8i-t has been reported. Analysis of the docked (PDB ID: 5IKR; A-Chain) poses of the compounds illustrated that they adopt identical conformations to the extremely selective COX-2 inhibitor. The biological outcomes as well as computational study suggested that the compounds originated to have elevated resemblance towards COX-2 enzyme than COX-1. The compounds 8i, 8l, 8q, 8r, 8s and 8t emerged as most potent and selective COX-2 inhibitors in contrast with Mefenamic acid. The selectivity index of 8l, 8n and 8r was respectively found to be 33.95, 20.25 and 24.98 which manifested their high selectivity against COX-2. Interestingly, the compounds which were active as COX-2 inhibitors were also active as antioxidant agents.

About Mequinol, If you have any questions, you can contact Nesaragi, AR; Kamble, RR; Dixit, S; Kodasi, B; Hoolageri, SR; Bayannavar, PK; Dasappa, JP; Vootla, S; Joshi, SD; Kumbar, VM or concate me.. HPLC of Formula: C7H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Nickel- and Palladium-Catalyzed Cross-Coupling of Aryl Fluorosulfonates and Phosphites: Synthesis of Aryl Phosphonates WOS:000609907500001 published article about SULFURYL FLUORIDE; BOND FORMATION; PHENOLS; ACIDS; ESTERS; SUFEX in [Zhang, Guofu; Wang, Jing; Guan, Chenfei; Ding, Chengrong] Zhejiang Univ Technol, Coll Chem Engn, Hangzhou 310014, Peoples R China; [Zhao, Yiyong] Zhejiang Ecol Environm Low Carbon Dev Ctr, Hangzhou 310012, Peoples R China in 2021, Cited 34. Computed Properties of C7H8O2. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5

The synthesis of aryl phosphonates via nickel and palladium-catalyzed cross-coupling of aryl fluorosulfonates and phosphites is described. The products were obtained in good to excellent yields under mild conditions with broad functional group compatibility, employing either Pd(OAc)(2) and DPEPhos or the readily available NiCl2(dme) and Xantphos as catalytic systems. Noteworthily, the present C(sp(2))-P bond formation method could be applied to the direct conversion of phenols to the corresponding aryl phosphonates in one pot via reaction of phenols with SO2F2 and subsequent palladium-catalyzed cross-coupling.

Computed Properties of C7H8O2. About Mequinol, If you have any questions, you can contact Zhang, GF; Wang, J; Guan, CF; Zhao, YY; Ding, CR or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about DNA CLEAVAGE; ANTITUBERCULAR AGENTS; PYRIMIDINE HYBRIDS; SCAFFOLD, Saw an article supported by the UGC New Delhi, IndiaUniversity Grants Commission, India [F117.1/201617/RGNF-2015-17-SC-MAH-26074/(SAIII/Website)]; UGC-SWRO, Bangalore [F.2070-MRP/15-16/KAKA056/UGC-SWRO]. Published in ELSEVIER in AMSTERDAM ,Authors: Mane, SG; Reddy, DS; Katagi, KS; Kumar, A; Munnolli, RS; Kadam, NS; Akki, MC; Nagarajaiah, H; Joshi, SD. The CAS is 150-76-5. Through research, I have a further understanding and discovery of Mequinol. SDS of cas: 150-76-5

In this work, a series of new 8-[(substituted 2-oxo-2H-chromen-4-yOmethyl]-8-azaspiro[4.5]decane-7,9-dione derivatives (1a – 1l) is synthesized and characterized by H-1 NMR, C-13 NMR, FT-IR, GC-MS and elemental analysis. In addition, the structure of compound 1k has been elucidated using single crystal X-ray diffraction techniques. The synthesized compounds are screened for their anticancer and anti-TB activity. Preliminary anticancer results showed that compounds (1a- 1l) exhibit moderate to potent activity against MDA-MB-231, A549, HT-29 and Hela cancer cell lines. Compound if exhibited the most potent activity against MDA-MB-231cell line with IC50 value of 9.05 mu M concentration, compound lg and 1h showed potent activity against A549 cell line with IC50 value of 7.05 and 13.31 mu M concentration respectively. Compound 1j showed good cytotoxicity against Hela cell line with IC50 of 16.14 mu M, whereas, compound 1l is found to be moderately active against HT-29 cell line with IC50 of 18.07 mu M. Anti-tubercular activity revealed that compound 1c, 1d, 1g, 1h and 1j have significant activity against MTBH(37)Rv strain with MIC 0.78, 1.56, 0.19, 0.39 and 0.78 mu g/mL respectively. Further, to investigate the mechanism of anti-TB activity and detailed intermolecular interactions between the synthesized compounds, molecular docking studies are performed. (C) 2020 Elsevier B.V. All rights reserved.

About Mequinol, If you have any questions, you can contact Mane, SG; Reddy, DS; Katagi, KS; Kumar, A; Munnolli, RS; Kadam, NS; Akki, MC; Nagarajaiah, H; Joshi, SD or concate me.. SDS of cas: 150-76-5

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Category: indole-building-block. In 2021.0 J MOL LIQ published article about THERMOTROPIC LIQUID-CRYSTALS; MESOPHASE BEHAVIOR; SIDE-CHAIN; BENZOTHIAZOLE MESOGEN; AZOBENZENE; IMPACT; ORIENTATION; BENZOATES; MONOMERS; SERIES in [Kamal, Salwa J.; Mahmud, H. N. M. Ekramul; Abdullah, Iskandar] Univ Malaya, Fac Sci, Dept Chem, Kuala Lumpur 50603, Malaysia; [Salleh, Noordini M.; Velayutham, Thamil Selvi; Zahid, N. Idayu] Univ Malaya, Ctr Fundamental & Frontier Sci Nanostruct Self As, Fac Sci, Dept Chem, Kuala Lumpur 50603, Malaysia; [Gopal, Sanjeev R.; Velayutham, Thamil Selvi] Univ Malaya, Fac Sci, Low Dimens Mat Res Ctr, Dept Phys, Kuala Lumpur 50603, Malaysia; [Kamal, Salwa J.] Imam Abdulrahman Bin Faisal Univ, Coll Sci, Dept Chem, POB 1982, Dammam 31441, Saudi Arabia in 2021.0, Cited 46.0. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5.

The effect of introducing a lateral methyl substituent and the two different alkoxy terminal groups on the mesophase behavior of three-benzene-ring molecular core of azo-ester compounds bearing 2-methylbutoxy unit on the opposite terminal side (C1-C6) were explored. Their structures were confirmed by several spectroscopic techniques (Fourier transform infrared spectroscopy, H-1 and C-13 nuclear magnetic resonance spectroscopy). The mesomorphic properties of these compounds were studied by differential scanning calorimetry, polarized optical microscopy, and small- and wide-angle X-ray scattering. Except for the un-substituted terminals (C1 and C4), all other derivatives are liquid crystalline, exhibiting enantiotropic nematic liquid crystal phase. The alteration of the alkoxy chain length from methoxy to butoxy at the phenyl ester terminal group (ring A) for each set of laterally-neat and laterally methyl-substituted mesogens decreases the nematic temperature range. A decrease in the mesophase temperature range is also observed when a lateral methyl substituent is incorporated into phenylazo ring of the mesogenic core (ring C). Optical study demonstrated that their absorption spectra are identical in shape due to the structural similarities of the mesogenic core. The corresponding fluorescence spectra exhibited blue-emission with the laterally methyl substituted compounds having a relatively higher fluorescence intensity compared to that of its laterally un-substituted analogues. Furthermore, the laterally methyl-substituted derivatives were subjected to the planar alignment and their dielectric and electro-optic properties were investigated. The nematic phase of the aligned samples shows antiferroelectric switching behavior with spontaneous polarization, P-s similar to 5 mu C/cm(2). (C) 2021 Elsevier B.V. All rights reserved.

About Mequinol, If you have any questions, you can contact Kamal, SJ; Salleh, NM; Mahmud, HNME; Abdullah, I; Gopal, SR; Velayutham, TS; Zahid, NI or concate me.. Category: indole-building-block

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Quality Control of Mequinol. In 2021 EUR J ORG CHEM published article about SULFURYL FLUORIDE; BOND FORMATION; PHENOLS; ACIDS; ESTERS; SUFEX in [Zhang, Guofu; Wang, Jing; Guan, Chenfei; Ding, Chengrong] Zhejiang Univ Technol, Coll Chem Engn, Hangzhou 310014, Peoples R China; [Zhao, Yiyong] Zhejiang Ecol Environm Low Carbon Dev Ctr, Hangzhou 310012, Peoples R China in 2021, Cited 34. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5.

The synthesis of aryl phosphonates via nickel and palladium-catalyzed cross-coupling of aryl fluorosulfonates and phosphites is described. The products were obtained in good to excellent yields under mild conditions with broad functional group compatibility, employing either Pd(OAc)(2) and DPEPhos or the readily available NiCl2(dme) and Xantphos as catalytic systems. Noteworthily, the present C(sp(2))-P bond formation method could be applied to the direct conversion of phenols to the corresponding aryl phosphonates in one pot via reaction of phenols with SO2F2 and subsequent palladium-catalyzed cross-coupling.

About Mequinol, If you have any questions, you can contact Zhang, GF; Wang, J; Guan, CF; Zhao, YY; Ding, CR or concate me.. Quality Control of Mequinol

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: 150-76-5. Authors Meng, HF; Yang, F; Chen, MJ; Chen, C; Zhu, BL in ROYAL SOC CHEMISTRY published article about in [Meng, Haifang; Yang, Fang; Chen, Mengjia; Chen, Chen; Zhu, Bolin] Tianjin Normal Univ, Coll Chem, Tianjin Key Lab Struct & Performance Funct Mol, Tianjin 300387, Peoples R China in 2021.0, Cited 37.0. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5

We have developed a Rh(iii)-catalyzed C-H alkenylation reaction of the N,N-bidentate chelating compound 2-(1H-pyrazol-1-yl)pyridine with alkenes via rollover cyclometalation. Mono- and dialkenyl-substituted 2-(1H-pyrazol-1-yl)pyridines could be selectively synthesized in moderate to good yields by tuning the reaction conditions. Further synthetic transformations were conducted to demonstrate the synthetic potential of our products.

About Mequinol, If you have any questions, you can contact Meng, HF; Yang, F; Chen, MJ; Chen, C; Zhu, BL or concate me.. Recommanded Product: 150-76-5

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Quality Control of Mequinol. Authors Wu, JY; Hu, ZJ; Sung, HL in ROYAL SOC CHEMISTRY published article about in [Wu, Jing-Yun; Hu, Zhi-Jia] Natl Chi Nan Univ, Dept Appl Chem, Nantou 545, Taiwan; [Sung, Hui-Ling] Natl Taiwan Normal Univ, Div Preparatory Programs Overseas Chinese Student, New Taipei 244, Taiwan in 2021.0, Cited 74.0. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5

A dinuclear molecular cadmium phosphonate, [Cd-2(H(4)tpmm)(2)(Hpybim)(2)(H2O)(4))center dot 2H(2)O (1.2H(2)O), emitting strong luminescence in both solid-state and suspension phases was synthesized by the reaction of Cd(ClO4)(2), 2,4,6-tris(phosphotylmethyl)mesitylene (H(6)tpmm), and 2-(2-pyridyl)benzimidazole (Hpybim) via the slow diffusion of reactants. Complex 1.2H(2)O showed very poor solubility but high chemical stability in common organic solvents and H2O. Furthermore, 1.2H(2)O also revealed good thermal stability upon heating to 325 degrees C. Luminescence detection on a series of phenolic analytes within 5 min response time showed that bisphenol AF (BPAF) and bisphenol B (BPB) significantly reduced the luminescence intensity of 1.2H(2)O in water, with the quenching efficiencies of 77 and 71%, respectively, while bisphenol Z (BPZ) moderately quenched the luminescence of 1.2H(2)O in water by 52%. The Stern-Volmer quenching constant, K-sv, and the limit of detection (LOD) were determined to be 1931 M-1 and 12.8 mu M for BPAF, 515 M-1 and 14.6 01 for BPB, and 2269 M-1 and 3.0 mu M for BPZ. In addition, 1.2H(2)O behaving as a luminescence sensor has an exclusive detection for BPAF, BPB, and BPZ over a wide range of interfering phenolic analytes, with the exception of dopamine toward BPB. This work demonstrates a highly waterstable molecular cadmium phosphonate suitable for the luminescence detection of bisphenols, endocrinedisrupting chemicals, especially BPAF and BPB, in water.

Quality Control of Mequinol. About Mequinol, If you have any questions, you can contact Wu, JY; Hu, ZJ; Sung, HL or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Phosphate linkers with traceable cyclic intermediates for self-immolation detection and monitoring WOS:000607300900006 published article about PROTECTING GROUPS; PKA VALUES; PHENOLS; MECHANISMS; CHEMISTRY; PRODRUG in [Prochazkova, Eliska; Straka, Michal] Czech Acad Sci, Inst Organ Chem & Biochem, Prague 16610, Czech Republic; [Simon, Petr; Baszczynski, Ondrej] Charles Univ Prague, Fac Sci, Prague 12843, Czech Republic; [Filo, Juraj; Majek, Michal; Cigan, Marek] Comenius Univ, Fac Nat Sci, Dept Organ Chem, Bratislava 84215, Slovakia in 2021.0, Cited 29.0. Computed Properties of C7H8O2. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5

Self-immolation (SI) is the key principle of ProTide nucleotide prodrugs such as remdesivir, which is currently used to treat COVID-19 patients. Developing novel tailor-made SI systems requires new analytical methods for the detection and monitoring of SI. We developed a robust method for SI analysis using novel phosphate-based SI linkers with NMR traceable cyclic intermediates to distinguish SI from alternative fragmentation pathways and to monitor cargo release in real time.

Computed Properties of C7H8O2. About Mequinol, If you have any questions, you can contact Prochazkova, E; Simon, P; Straka, M; Filo, J; Majek, M; Cigan, M; Baszczynski, O or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: C7H8O2. In 2021.0 ORG LETT published article about CROSS-COUPLING REACTION; ARYL ETHERS; ACIDS in [Pein, Wesley L.; Wiensch, Eric M.; Montgomery, John] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA in 2021.0, Cited 52.0. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5.

The conversion of silyloxyarenes to boronic acid pinacol esters via nickel catalysis is described. In contrast to other borylation protocols of inert C-O bonds, the method is competent in activating the carbon-oxygen bond of silyloxyarenes in isolated aromatic systems lacking a directing group. The catalytic functionalization of benzyl silyl ethers was also achieved under these conditions. Sequential cross-coupling reactions were achieved by leveraging the orthogonal reactivity of silyloxyarenes, which could then be functionalized subsequently.

About Mequinol, If you have any questions, you can contact Pein, WL; Wiensch, EM; Montgomery, J or concate me.. HPLC of Formula: C7H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles