Category: 2208-59-5

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, is researched, Molecular C12H9N3, CAS is 2208-59-5, about A novel two-dimensional cadmium(II) complex: poly[diaquatris(μ4-cyclohexane-1,4-dicarboxylato)bis[2-(pyridin-4-yl)-1H-benzimidazole]tricadmium(II), the main research direction is crystal structure cadmium pyridinylbenzimidazole cyclohexanedicarboxylato aqua trinuclear complex; mol structure cadmium pyridinylbenzimidazole cyclohexanedicarboxylato aqua trinuclear complex; hydrogen bond cadmium pyridinylbenzimidazole cyclohexanedicarboxylato aqua trinuclear complex; pi stacking cadmium pyridinylbenzimidazole cyclohexanedicarboxylato aqua trinuclear complex; cadmium pyridinylbenzimidazole cyclohexanedicarboxylato aqua trinuclear complex thermal emission property; cadmium complex; crystal structure; dicarboxylate; metal-organic framework; two-dimensional coordination polymer.Computed Properties of C12H9N3.

The title compound, [Cd3(C8H10O4)3(C12H9N3)2(H2O)2]n or [Cd3(chdc)3(4-PyBIm)2(H2O)2]n, was synthesized hydrothermally from the reaction of Cd(CH3COO)2·2H2O with 2-(pyridin-4-yl)-1H-benzimidazole (4-PyBIm) and cyclohexane-1,4-dicarboxylic acid (1,4-chdcH2). The asym. unit consists of one and a half CdII cations, one 4-PyBIm ligand, one and a half 1,4-chdc2- ligands and one coordinated water mol. The central CdII cation, located on an inversion center, is coordinated by six carboxylate O atoms from six 1,4-chdc2- ligands to complete an elongated octahedral coordination geometry. The two terminal rotationally sym. CdII cations each exhibits a distorted pentagonal-bipyramidal geometry, coordinated by one N atom from 4-PyBIm, five O atoms from three 1,4-chdc2- ligands and one O atom from an aqua ligand. The 1,4-chdc2- ligands possess two conformations, i.e. e,e-trans-chdc2- and e,a-cis-chdc2-. The cis-1,4-chdc2- ligands bridge the CdII cations to form a trinuclear {Cd3}-based chain along the b axis, while the trans-1,4-chdc2- ligands further link adjacent one-dimensional chains to construct an interesting two-dimensional network.

After consulting a lot of data, we found that this compound(2208-59-5)Computed Properties of C12H9N3 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, is researched, Molecular C12H9N3, CAS is 2208-59-5, about Acidic properties of benzimidazoles and substituent effects. IV. Relationship between the acidities of N’-(substituted phenyl)arylamidines and ring closures to imidazole, the main research direction is benzimidazole substituent effect acidity; amidine aryl cyclization substituent effect; phenylenediamine cyclocondensation pyridinecarboxylic acid; LFER acidity benzimidazole pyridyl.Product Details of 2208-59-5.

Benzimidazoles I (R = H, Me, Cl, MeO, NO2; R1 = Ph, pyridinyl) were prepared by cyclocondensation of 1,2-(H2N)2C6H3R with R1CO2H in polyphosphoric acid at 170-80° or by cyclocondensation of 1,2-(H2N)2C6H3R with R1Me in the presence of S. Alternatively, I were also prepared by cyclization of amidines RC6H4NHC(:NH)R1 (II) by successive treatment with aqueous NaOCl and then with Na2CO3. Cyclization of II (R = C-3 substituted) by the latter method gave mixtures of C-7 and C-5 substituted benzimidazoles which were separated by crystallization Acidities of II increased with increasing electron withdrawing power of R, and, as the acidity of II increased, yields of I from cyclization of II decreased. Acidities of C-7 substituted I were correlated by the Taft equation with ρ = 0.45, whereas acidities of C-5 substituted I (R1 = pyridyl) were correlated by the Hammett equation with ρ = 1.3.

After consulting a lot of data, we found that this compound(2208-59-5)Product Details of 2208-59-5 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 2208-59-5. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, is researched, Molecular C12H9N3, CAS is 2208-59-5, about Visible-light-promoted synthesis of benzimidazoles. Author is Park, Sehyun; Jung, Jaehun; Cho, Eun Jin.

A simple and environmentally friendly synthetic method for benzimidazoles, which are important structural motifs in many applications owing to their various biol. functions, was developed. The reaction of o-phenylenediamine and a variety of aliphatic/aromatic aldehydes in methanol proceeds at room temperature with only natural sources, mol. oxygen and visible light.

After consulting a lot of data, we found that this compound(2208-59-5)SDS of cas: 2208-59-5 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Crystal Growth & Design called Anion-Controlled Assembly of Silver(I) Complexes of Multiring Heterocyclic Ligands: A Structural and Photophysical Study, Author is Kundu, Nabanita; Audhya, Anandalok; Abtab, Sk Towsif Md; Ghosh, Sanjib; Tiekink, Edward R. T.; Chaudhury, Muktimoy, which mentions a compound: 2208-59-5, SMILESS is C1(C2=CC=NC=C2)=NC3=CC=CC=C3N1, Molecular C12H9N3, Safety of 2-(Pyridin-4-yl)-1H-benzo[d]imidazole.

Four multiring heterocyclic ligands with benzimidazole (L1 and L3) and benzothiazole nuclei (L2 and L4) are reported. Their silver(I) complexes involving a variety of anions (both organic and inorganic) have been prepared by the process of self-assembly and structurally characterized by single-crystal x-ray diffraction analyses. Discrete metallocyclic complexes [Ag(L3)(X)]2 (X = NO3-, 3a; cis-HOOCCH:CHCOO-, 3b; 0.5SiF62-, 3c) and [Ag(L4)(Y)]2 (Y = NO3-, 4a; CF3SO3-, 4b) have been formed with the ligands L3 and L4, resp., where the pyridine nitrogen atom N1 is in the 3-position as against the coordination polymers [Ag(L1)(H2O)(NO3)]n, 1a, [Ag(L1)(CF3COO)]n, 1b and {2[Ag(L2)2(ClO4)].0.5.C2H5OH}n 2a, and [Ag(L2)2(cis-HOOCCH:CHCOO)]n, 2b, with the ligands L1 and L2, resp., in which the N1 atom occupies the 4-position in the pyridine ring. In addition to the primary ligands (L1-L4), the counteranions also have a dominant influence on the overall structures of these compounds Secondary bonding interactions, namely, hydrogen bonding, π···π-stacking, and C-H···π interactions, are also proven effective in shaping the dimensionalities of the solid state structures. Thus, a zigzag chain structure of 1a mediated by a nitrate anion generates a more complicated double layer structure in 1b where trifluoroacetate has replaced nitrate as the counterion. Discrete 12-membered metallocycles in 3a-3c generate 2-D arrays of flat (3a) and undulating topologies (3b and 3c), depending upon the type of their associated anions. Metallocycles 4a and 4b have less complicated structures compared to those of 3a-3c because of the replacement of NH by S in the heterocyclic ring, thereby reducing the hydrogen-bonding potential in the primary ligand in going from L3 to L4. In the solid state, the complexes show enhanced phosphorescence at 77 K with triplet lifetime in the range of 0.5-0.8 s, much shorter than those for the free ligands (2.3 – 3.3 s) because of increased spin-orbit coupling introduced by the coordinated Ag+ ion. This heavy-atom effect also has a causative influence in shortening the fluorescence lifetimes of these compounds

The article 《Anion-Controlled Assembly of Silver(I) Complexes of Multiring Heterocyclic Ligands: A Structural and Photophysical Study》 also mentions many details about this compound(2208-59-5)Safety of 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, you can pay attention to it, because details determine success or failure

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: 2208-59-5. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, is researched, Molecular C12H9N3, CAS is 2208-59-5, about Prototropic equilibria of 2-pyridylbenzimidazoles in aqueous solution. Author is Novo, Mercedes; Mosquera, Manuel; Rodriguez Prieto, Flor.

The acid-base behavior of 2-(n’-pyridyl)benzimidazoles (n’ = 2,3,4) and some Me derivatives was studied in aqueous solution over a wide range of acidity; interesting features with respect to competition in protonation between the benzimidazole N3 and the pyridyl N were observed along with the existence of the corresponding 2 monocations in equilibrium in the case of n’ = 4. The influence of pH on the electronic absorption spectra of all these compounds was studied to identify the ground-state species present as a function of acidity and to obtain the acidity constants of the various prototropic equilibrium occurring in the wide range of acidity studied.

The article 《Prototropic equilibria of 2-pyridylbenzimidazoles in aqueous solution》 also mentions many details about this compound(2208-59-5)HPLC of Formula: 2208-59-5, you can pay attention to it, because details determine success or failure

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Luminescent humidity sensors based on porous Ln3+-MOFs, published in 2012, which mentions a compound: 2208-59-5, mainly applied to luminescent humidity sensor porous lanthanide metal organic framework, Formula: C12H9N3.

Two new types of luminescence-based Ln3+-MOF humidity sensors were reported. The humidity sensing is successfully realized by controlling O-H oscillators on the Ln3+ emitters through host-guest H-bonding interactions.

After consulting a lot of data, we found that this compound(2208-59-5)Formula: C12H9N3 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, is researched, Molecular C12H9N3, CAS is 2208-59-5, about Syntheses, Structures, and Photoluminescent Properties of Three Silver(I) Coordination Polymers with 2-(4-Pyridyl)benzimidazole. Author is Xia, Chang-Kun; Lu, Can-Zhong; Zhang, Quan-Zheng; He, Xiang; Zhang, Jian-Jun; Wu, Ding-Ming.

Three Ag(I) coordination polymers, [Ag2(PyBIm)2(H2O)2]SO4·H2O (1), [Ag3(PyBIm)3(μ2-SO4)(HSO4)]·3H2O (2), and [Ag2(PyBIm)2(μ2-SO4)]·4H2O (3) [PyBIm = 2-(4-pyridyl)benzimidazole] were synthesized by hydrothermal methods. The Ag(I) atoms in 1-3 are all three coordinated, bridged by PyBIm ligands via NPy and NBIm donor atoms into a 1-dimensional zigzag chain based on the [Ag2(PyBIm)2]2+ unit. The sulfate groups are not coordinated in 1, while they act as bridging ligands in 2 and 3; with the help of μ2-SO4, such zigzag chains are linked into a belt with a ternary-chain structural motif in 2, however, in 3, a two-dimensional network is observed All the complexes display room-temperature photoluminescence in the visible region, which may be assigned to metal-to-ligand charge transfer.

After consulting a lot of data, we found that this compound(2208-59-5)Recommanded Product: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, is researched, Molecular C12H9N3, CAS is 2208-59-5, about Ultrafast excited state intermolecular proton transfer dynamics of 2-(4′-Pyridyl)benzimidazole inside the nanocavity of reverse micelles.Recommanded Product: 2208-59-5.

The effect of AOT reverse micelle on the excited state prototropism of 2-(4′-pyridyl)benzimidazole (4PBI) have been explored by steady-state and time-resolved fluorescence spectroscopy. It has been observedthat the effect AOT reverse micelle is remarkably different form the CTAB reverse micelle on the photophysics of 4PBI. The ESPT dynamics in AOT reverse micelle approaches to bulk water at higher water concentrationwhereas no ESPT is observedin CTAB reverse micelle even at high w0 value. In AOT reverse micelle, 4PBI can penetrate the interfacial wall and undergo ESPT processes. This process might be initiated by the electrostatic interaction between the neg.charged interface of AOT reverse micelle and pos.charged monocation ca.tautomer, which is selectively stabilized. In addition, no such possibility is observedin CTAB reverse micelle. The ESPT dynamics of dye was found to be slowed down inside the AOT reverse micelle. The observedslow ESPT dynamics in reverse micelle compared to bulk water is mainly attributed to the slow hydrogen-bonded network dynamics of water mols.inside the nanopools of AOT reverse micelle.

After consulting a lot of data, we found that this compound(2208-59-5)Recommanded Product: 2208-59-5 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Quality Control of 2-(Pyridin-4-yl)-1H-benzo[d]imidazole. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, is researched, Molecular C12H9N3, CAS is 2208-59-5, about Cobalt-mediated synthesis of 2-(4-pyridyl)benzimidazole. X-ray structures of Co[2-(4-pyridyl)benzimidazole]2(H2O)2(NO3)2 and [Co(isonicotinate)(4-pyridinium carboxylate)(H2O)(NO3)]∞. Author is Wang, Zhiyong; Wilson, Scott R.; Foxman, Bruce M.; Lin, Wenbin.

We have observed an unusual example of cobalt-mediated cyclization of 4-pyridinecarboxaldehyde and 2-nitroaniline to afford 2-(4-pyridyl)benzimidazole under hydro(solvo)thermal conditions. Reaction of Co(NO3)2·6H2O with 4-pyridinecarboxaldehyde and 2-nitroaniline in ethanol at 120° gave a cobalt(II) coordination compound, Co[2-(4-pyridyl)benzimidazole]2(H2O)2(NO3)2 (I). In contrast, when the hydro(solvo)thermal reaction was carried out between Co(NO3)2·6H2O and isonicotinic acid in the presence of 2-nitroaniline at 110°, a one-dimensional Co(II) coordination polymer with the formula of [Co(isonicotinate)(4-pyridinium carboxylate)(H2O)(NO3)]∞ (II) resulted. The x-ray single crystal structures of both I and II are described. Interestingly, the isonicotinic acid in II exists as a 4-pyridinium carboxylate tautomer, and the pyridinium hydrogen atom forms a very strong hydrogen bond to the carboxylate oxygen of the 4-pyridinium carboxylate on an adjacent metal center. I forms a three-dimensional polymeric network through hydrogen bonding interactions, while II exists as a 2-D bilayer polymeric network through hydrogen bonding interactions.

After consulting a lot of data, we found that this compound(2208-59-5)Quality Control of 2-(Pyridin-4-yl)-1H-benzo[d]imidazole can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole( cas:2208-59-5 ) is researched.Recommanded Product: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole.Yang, Yan; Zeng, Ming-Hua; Zhang, Lai-Jun; Liang, Hong published the article 《A zinc(II) coordination polymer, [Zn4(o-bda)4(p-pbim)4]n, with strong blue fluorescence》 about this compound( cas:2208-59-5 ) in Journal of Coordination Chemistry. Keywords: zinc pyridylbenzimidazole phenylenediacetato polymeric complex preparation structure; crystal structure zinc pyridylbenzimidazole phenylenediacetato polymeric complex; fluorescence zinc pyridylbenzimidazole phenylenediacetato polymeric complex. Let’s learn more about this compound (cas:2208-59-5).

A zinc(II) coordination polymer, [Zn4(o-bda)4(p-pbim)4]n (1) (p-pbim = 4-pyridylbenzimidazole, o-bda2- = o-phenylenediacetic acid dianion), has been synthesized by hydrothermal method and characterized by elemental anal., IR, TG, photoluminescence and X-ray single crystal diffraction. Complex 1 crystallizes in a monoclinic system and space group P21/n, with a = 14.231(3) Å, b = 16.257(4) Å, c = 16.794(4) Å, β = 100.262(1)°, and Z = 8; R1 for 6475 observed reflections [I > 2σ(I)] was 0.0420. Complex 1 shows a bi-chain structure fabricated by the tetranuclear zinc unit. Two zinc(II) ions are five coordinate with distorted trigonal-bipyramid geometry and the other two zinc(II) ions are four coordinate with distorted tetrahedral geometry. Complex 1 builds the 1-D bi-chain structure with two different sub-rings A and B, which are 32-member and 14-member rings, resp. There exists a 2-D supramol. network linked by hydrogen-bonding interactions (2.695 and 2.807 Å). A 3-D supramol. network is further constructed by non-covalent interactions between the 1-D bi-chain structure. The TG/DTG shows that the chain skeleton is thermally stable to 356°C. Blue fluorescent emission of the complex was determined at 404 nm in the solid state with short decay lifetime of 1.67 ns.

Although many compounds look similar to this compound(2208-59-5)Recommanded Product: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, numerous studies have shown that this compound(SMILES:C1(C2=CC=NC=C2)=NC3=CC=CC=C3N1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles