2208-59-5 | - Page 7 of 8 - Indole Building Blocks

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From this literature《Self-assembled tetranuclear metallacyclic chair using orthogonal tritopic acceptors, angular ditopic donors, and bischelating bridging motifs》,we know some information about this compound(2208-59-5)Category: indole-building-block, but this is not all information, there are many literatures related to this compound(2208-59-5).

Shankar, Bhaskaran; Rajakannu, Palanisamy; Kumar, Surendra; Gupta, Deepak; Kannan, Tharanikkarasu; Sathiyendiran, Malaichamy published an article about the compound: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole( cas:2208-59-5,SMILESS:C1(C2=CC=NC=C2)=NC3=CC=CC=C3N1 ).Category: indole-building-block. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:2208-59-5) through the article.

A self-assembled neutral tetrarhenium mol. chair, [((OC)3Re(μ-CA)Re(CO)3)2(μ-EpBim)2] (H2CA = chloranilic acid, EpBim = 2-(4-pyridyl)-1-ethylbenzimidazole), was prepared using orthogonal tritopic acceptors, angular ditopic N-donors (∼ 80°), and linear bis-chelating bridging donors in a 1-step process.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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From this literature《Benzazoles from Aliphatic Amines and o-Amino/Mercaptan/Hydroxyanilines: Elemental Sulfur as a Highly Efficient and Traceless Oxidizing Agent》,we know some information about this compound(2208-59-5)Safety of 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, but this is not all information, there are many literatures related to this compound(2208-59-5).

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Nguyen, Thanh Binh; Ermolenko, Ludmila; Dean, William A.; Al-Mourabit, Ali researched the compound: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole( cas:2208-59-5 ).Safety of 2-(Pyridin-4-yl)-1H-benzo[d]imidazole.They published the article 《Benzazoles from Aliphatic Amines and o-Amino/Mercaptan/Hydroxyanilines: Elemental Sulfur as a Highly Efficient and Traceless Oxidizing Agent》 about this compound( cas:2208-59-5 ) in Organic Letters. Keywords: benzazole preparation alkylamine aniline coupling sulfur oxidizing agent. We’ll tell you more about this compound (cas:2208-59-5).

A novel remarkably simple solvent-free and catalyst-free synthesis of benzazoles from alkylamines and o-hydroxy/amino/mercaptan anilines using elemental sulfur as traceless oxidizing agent has been developed.

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From this literature《Quantitative structure-activity relationships (QSAR) of smooth muscle relaxation and 2-substituted, benzimidazole derivatives》,we know some information about this compound(2208-59-5)HPLC of Formula: 2208-59-5, but this is not all information, there are many literatures related to this compound(2208-59-5).

HPLC of Formula: 2208-59-5. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, is researched, Molecular C12H9N3, CAS is 2208-59-5, about Quantitative structure-activity relationships (QSAR) of smooth muscle relaxation and 2-substituted, benzimidazole derivatives. Author is Buyukbingol, Erdem; Safak, Cihat; Ozturk, Yusuf; Sahin, M. Fethi.

A series of the 2-substituted benzimidazole derivatives were tested for smooth muscle relaxation activity in rats. The pD2 and potency values were then analyzed in terms of hydrophobic (logP), electronic (dipole moment), and stereochem. (νw) factors by linear and multiple regression anal. The activity is depended parabolically on logP with the 2 other factors involved in the regression model. A correlation of pD2 with dipole moment was observed In all other model attempts the nonsignificant correlation led to suggest that mol. shape and size of the compounds would be unimportant in their smooth muscle relaxation activity in term of νw.

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From this literature《Influence of the molecular structure on the inhibitor properties of benzimidazole derivatives on mild steel corrosion in 1 M hydrochloric acid》,we know some information about this compound(2208-59-5)HPLC of Formula: 2208-59-5, but this is not all information, there are many literatures related to this compound(2208-59-5).

HPLC of Formula: 2208-59-5. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, is researched, Molecular C12H9N3, CAS is 2208-59-5, about Influence of the molecular structure on the inhibitor properties of benzimidazole derivatives on mild steel corrosion in 1 M hydrochloric acid. Author is Popova, A.; Christov, M.; Deligeorgiev, T..

Six benzimidazole derivatives were investigated as corrosion inhibitors for mild steel in 1 M HCl by using gravimetric and polarization techniques. The inhibitor efficiency depended on the concentration and on structure of the mols. The results were interpreted by using an adsorption model based on inhibitor adsorption in the form of non-protonated and protonated mols. Five of the six examined compounds adsorbed according to the Frumkin adsorption isotherm. An attempt was made to find a correlation between the inhibition efficiency and some parameters of the electronic structure of the mol., like induction and resonance effects of the substituents and ionization potential. A correlation also was attempted between the inhibition efficiency and some parameters of the chem. structure of the mol., like the mol. area and others. No simple correlation was found.

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There is still a lot of research devoted to this compound(SMILES：C1(C2=CC=NC=C2)=NC3=CC=CC=C3N1)Reference of 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, and with the development of science, more effects of this compound(2208-59-5) can be discovered.

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy called Research on differences between 2-(2′-pyridyl)benzimidazole and 2-(4′-pyridyl)benzimidazole based on terahertz time-domain spectroscopy, Author is Song, Maojiang; Yang, Fei; Liu, Liping; Su, Caixia, which mentions a compound: 2208-59-5, SMILESS is C1(C2=CC=NC=C2)=NC3=CC=CC=C3N1, Molecular C12H9N3, Reference of 2-(Pyridin-4-yl)-1H-benzo[d]imidazole.

Due to the important pharmaceutical activities of benzimidazole derivatives, the differences between 2-(2′-pyridyl)benzimidazole and 2-(4′-pyridyl)benzimidazole were researched by terahertz time-domain spectroscopy and d. functional theory systematically. Although the only difference between their mol. configurations is the different arrangement of nitrogen on pyridine ring, 2PBI and 4PBI have large differences in their exptl. absorption spectra in the range of 0.2-2.5 THz, such as the amount, amplitude and frequency position of absorption peaks. The validity of these results was confirmed by the theor. results simulated using d. functional theory. The possible reasons of these differences originate from the different dihedral angles between benzimidazole ring and pyridine ring and the different hydrogen-bonding interactions within crystal cell.

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There is still a lot of research devoted to this compound(SMILES：C1(C2=CC=NC=C2)=NC3=CC=CC=C3N1)SDS of cas: 2208-59-5, and with the development of science, more effects of this compound(2208-59-5) can be discovered.

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Benzimidazole derivatives》. Authors are Novelli, Armando.The article about the compound:2-(Pyridin-4-yl)-1H-benzo[d]imidazolecas:2208-59-5,SMILESS:C1(C2=CC=NC=C2)=NC3=CC=CC=C3N1).SDS of cas: 2208-59-5. Through the article, more information about this compound (cas:2208-59-5) is conveyed.

The preparation of benzimidazoles related to pharmacologically active substances is described. The Mannich reaction takes place with 2-substituted benzimidazoles. 2-Benzylbenzimidazole (5.62 g.) in 50 cc. MeOH and 2.4 g. morpholine (I) in 25 cc. MeOH chilled and treated dropwise with 2.4 g. of 38% CH2O (II) yielded on crystallization of the product from C6H6 6 g. 1-morpholinomethyl-2-benzylbenzimidazole, C19H21N3O, m. 118-20°. Similarly, condensation of 6.3 g. (p-nitrobenzyl)benzimidazole in 90 cc. MeOH with 2 g. I in 25 cc. MeOH with dropwise addition of 2.4 g. II in 20 cc. MeOH produced 4 g. (46%) 1-morpho-linomethyl-2-(p-nitrobenzyl)benzimidazole, m. 210°. Refluxing 5 g. o-C6H4(NH2)2 and 10 g. isonicotinic acid (III) with 30 cc./HCl (d. 1.19) and 20 cc. H2O 12 hrs. at 130-50° gave 3-6 g. (40%) 2-(4-pyridyl)benzimidazole, m. 219-20° Similar condensation of 7.5 g. of 4,5,1,2-Me2C6H2(NH2)2 with 12 g. III in HCl 20 hrs. at 150-70° yielded 4 g. (30%) 5,6-dimethyl-2-(4-pyridyl)benzimidazole, m. 239-40°.

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There is still a lot of research devoted to this compound(SMILES：C1(C2=CC=NC=C2)=NC3=CC=CC=C3N1)Synthetic Route of C12H9N3, and with the development of science, more effects of this compound(2208-59-5) can be discovered.

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Excited-State Behavior of 2-(4′-Pyridyl)benzimidazole in Aqueous Solution: Proton-Transfer Processes and Dual Fluorescence, published in 1995-10-05, which mentions a compound: 2208-59-5, mainly applied to excited state reaction pyridylbenzimidazole proton transfer; photolysis pyridylbenzimidazole proton transfer, Synthetic Route of C12H9N3.

The excited-state acid-base behavior of 2-(4′-pyridyl)benzimidazole in aqueous solution has been studied over a wide range of acidity by UV absorption and fluorescence spectroscopy. The species detected in the lowest electronically excited singlet state turned out to be identical to those of the ground state: the anion A, the neutral mol. N, the monocation C protonated at the benzimidazole N3, the monocation T protonated at the pyridyl nitrogen, and the dication D. Nevertheless, the strong increase in the basicity of the pyridyl nitrogen atom in the excited state induces different excited-state proton-transfer processes. The dual fluorescence of 4PBI at neutral pH is explained by the protonation of N* to give T*. On the basis of the steady-state data together with the fluorescence decay measurements at several acidities, a mechanism is proposed to explain the acid-base behavior of 4PBI in the first excited singlet state.

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There is still a lot of research devoted to this compound(SMILES：C1(C2=CC=NC=C2)=NC3=CC=CC=C3N1)HPLC of Formula: 2208-59-5, and with the development of science, more effects of this compound(2208-59-5) can be discovered.

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 2208-59-5, is researched, SMILESS is C1(C2=CC=NC=C2)=NC3=CC=CC=C3N1, Molecular C12H9N3Journal, Zeitschrift fuer Anorganische und Allgemeine Chemie called Hydrothermal Synthesis of Five New Coordination Polymers Based on Benzophenone-2, 4′-dicarboxylic Acid and N-Donor Spacers, Author is Xu, Jiakun; Sun, Xiaochun; Fan, Yuhua; Sun, Mi; Bi, Caifeng, the main research direction is zinc nickel benzophenonedicarboxylate coordination polymer preparation fluorescence; crystal structure zinc nickel benzophenonedicarboxylate coordination polymer.HPLC of Formula: 2208-59-5.

Five new coordination polymers, [[Ni2(L)2(4,4′-bipy)3]·H2O]n (1), [Ni2(L)2(O)(bpp)2]n (2), [Zn(L)(bib)0.5]n (3), [Zn(L)(PyBIm)]n (4), and [Zn3(L)2(OH)(Im)]n (5) [H2L = benzophenone-2,4′-dicarboxylic acid, 4,4′-bipy = 4,4′-bipyridine, bpp = 1,3-bis(4-pyridyl)propane, PyBIm = 2-(4-pyridyl)benzimidazole, and Im = imidazole] were synthesized under hydrothermal conditions. Structure determination revealed that compound 1 is a 3-dimensional network and exhibits a 4-connected metal-organic framework with (42.63.8) topol., whereas compounds 2, 3, 4, and 5 are two-dimensional layer structures. In compounds 2-4, dinuclear metal clusters are formed through carboxylic groups. In compound 5, trinuclear metal clusters are formed through μ3-OH and carboxylic groups. The carboxylic groups exhibit three coordination modes in compounds 1-5: monodentately, bidentate-chelating, and bis-monodentately. Also, the luminescent properties for compounds 3, 4, and 5 were studied.

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There is still a lot of research devoted to this compound(SMILES：C1(C2=CC=NC=C2)=NC3=CC=CC=C3N1)Computed Properties of C12H9N3, and with the development of science, more effects of this compound(2208-59-5) can be discovered.

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Crystal Growth & Design called A Series of Inorganic-Organic Hybrid Composite Solids Based on Molybdenum Oxide Chains, Author is Chen, Li-Juan; He, Xiang; Xia, Chang-Kun; Zhang, Quan-Zheng; Chen, Jiu-Tong; Yang, Wen-Bin; Lu, Can-Zhong, which mentions a compound: 2208-59-5, SMILESS is C1(C2=CC=NC=C2)=NC3=CC=CC=C3N1, Molecular C12H9N3, Computed Properties of C12H9N3.

Six inorganic-organic compounds based on [MoxOy]n- chains, [Ag2(quinoxaline)2Mo4O13] (1), [Cu2(DMPz)2Mo4O13] (2) (DMPz = 2,5-dimethylpyrazine), [Cu2(4-PBIM)2Mo4O13] (3) [4-PBIM = 2-(4-pyridyl)benzimidazole], [Cu(OPBIM)(H2O) Mo3O10]·H2O (4) [OPBIM = 2-(2-ol-3-pyridinio)benzimidazole], [Co(3-HPBIM)2 (H2O)2Mo6O20] (5) [3-HPBIM = 2-(3-pyridyl)benzimidazolium], [Ni(3-HPBIM)2(H2O)2Mo6O20] (6), were hydrothermally synthesized and characterized by single-crystal x-ray diffraction. Compounds 1 and 2 represent the 1st two examples of three-dimensional frameworks constructed from [Mo8O26]n4n- anion chains integrated by M-L polymeric cation chains. Compounds 3 and 4 reveal the peripheral decorated [Mo8O26]n4n- and [Mo3O10]n2n- 1-dimensional chains, resp. The isostructural compounds 5 and 6 feature two-dimensional networks formed from [Mo3O10]2n4n- infinite chains linked by [Co(3-HPBIM)2]4+ fragments. The molybdate chains in compounds 1-3 and 4-6 represent three isomeric forms of [Mo8O26]n4n- and two [Mo3O10]n2n- chains, resp.

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There is still a lot of research devoted to this compound(SMILES：C1(C2=CC=NC=C2)=NC3=CC=CC=C3N1)Name: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, and with the development of science, more effects of this compound(2208-59-5) can be discovered.

Name: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, is researched, Molecular C12H9N3, CAS is 2208-59-5, about 1-Methyl-4-(1-methyl-1H-benzimidazol-2-yl)pyridinium iodide. Author is Wang, Fang-Ming.

The cation of 1-methyl-4-(1-methyl-1H-benzimidazol-2-yl)pyridinium iodide, C14H14N3+·I-, is nonplanar, the dihedral angle between the benzimidazole and the 1-methylpyridinium planes being 37.4(2)°. The crystal structure is stabilized by weak π-π stacking interactions, the centroid-centroid distances between 1-methylimidazole and benzimidazole planes being 3.678(4) Å. Crystallog. data are given.