Category: 98-17-9

An article Design, Synthesis, and Herbicidal Activity of Novel Diphenyl Ether Derivatives Containing Fast Degrading Tetrahydrophthalimide WOS:000526399200005 published article about 6 LEAF VEGETABLES; PROTOPORPHYRINOGEN; RESIDUE in [Zhao, Li-Xia; Jiang, Mao-Jun; Hu, Jia-Jun; Zou, Yue-Li; Cheng, Yuan; Ren, Tao; Gao, Shuang; Fu, Ying; Ye, Fei] Northeast Agr Univ, Coll Sci, Dept Appl Chem, Harbin 150030, Peoples R China in 2020, Cited 42. The Name is 3-(Trifluoromethyl)phenol. Through research, I have a further understanding and discovery of 98-17-9. HPLC of Formula: C7H5F3O

To seek new protoporphyrinogen oxidase (PPO) inhibitors with better biological activity, a series of novel diphenyl ether derivatives containing tetrahydrophthalimide were designed based on the principle of substructure splicing and bioisomerization. PPO inhibition experiments exhibited that 6c is the most potential compound, with the half-maximal inhibitory concentration (IC50) value of 0.00667 mg/L, showing 7 times higher activity than Oxyfluorfen (IC50 = 0.0426 mg/L) against maize PPO and similar herbicidal activities to Oxyfluorfen in weeding experiments in greenhouses and field weeding experiments. In view of the inspected bioactivities, the structure-activity relationship (SAR) of this series of compounds was also discussed. Crop selection experiments demonstrate that compound 6c is safe for soybeans, maize, rice, peanuts, and cotton at a dose of 300 g ai/ha. Accumulation analysis experiments showed that the accumulation of 6c in some crops (soybeans, peanuts, and cotton) was significantly lower than Oxyfluorfen. Current work suggests that compound 6c may be developed as a new herbicide candidate in fields.

HPLC of Formula: C7H5F3O. About 3-(Trifluoromethyl)phenol, If you have any questions, you can contact Zhao, LX; Jiang, MJ; Hu, JJ; Zou, YL; Cheng, Y; Ren, T; Gao, S; Fu, Y; Ye, F or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Yang, S; Xiong, MF; Tian, WQ; Zhang, H; Xiao, XY; Liu, HY; Chang, CK in [Yang, Shuang; Xiong, Ming-Feng; Tian, Wan-Qun; Zhang, Hao; Xiao, Xin-Yan; Liu, Hai-Yang] South China Univ Technol, Dept Chem, Key Lab Funct Mol Engn Guangdong Prov, Guangzhou 510641, Peoples R China; [Chang, Chi-Kwong] Michigan State Univ, Dept Chem, E Lansing, MI 48824 USA published Construction of C-O bond via cross-dehydrogenative coupling of sp [3] C-H bond with phenols catalyzed by copper porphyrin in 2020, Cited 42. Name: 3-(Trifluoromethyl)phenol. The Name is 3-(Trifluoromethyl)phenol. Through research, I have a further understanding and discovery of 98-17-9.

Copper porphyrin-catalyzed construction of ether bond by cross-dehydrogenative coupling of sp [3] C-H bond with phenols bearing electron-withdrawing groups (EWG) was described for the first time. A broad range of substrates afforded different acetals in moderate to excellent yields with good functional group tolerance. The developed method is not only suitable for phenol substrates with ortho-directing groups, but also suitable for those phenol without ortho-directing groups. Significantly, a high turnover number (TON) up to 7300 was achieved in gram-level test. (C) 2020 Elsevier Ltd. All rights reserved.

About 3-(Trifluoromethyl)phenol, If you have any questions, you can contact Yang, S; Xiong, MF; Tian, WQ; Zhang, H; Xiao, XY; Liu, HY; Chang, CK or concate me.. Name: 3-(Trifluoromethyl)phenol

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about TERMINAL ALKYNES; CATALYZED 1,2-ADDITION; RADICAL-ADDITION; SULFONYLATION; GENERATION; EFFICIENT; INSERTION; SULFONES; IODIDES, Saw an article supported by the CSIR-UGCCouncil of Scientific & Industrial Research (CSIR) – IndiaUniversity Grants Commission, India; CSIR-Network projectCouncil of Scientific & Industrial Research (CSIR) – India [BSC0102/BSC0108]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Ansari, MY; Kumar, N; Kumar, A. The CAS is 98-17-9. Through research, I have a further understanding and discovery of 3-(Trifluoromethyl)phenol. Recommanded Product: 3-(Trifluoromethyl)phenol

The first regioselective phenoxysulfonylation of alkynes with sodium sulfinate and phenol catalyzed by I-2/base has been uncovered. This metal-free, one-pot alkyne difunctionalization process provides various (Z)-beta-phenoxy vinylsulfones under mild reaction conditions. A variety of terminal as well as internal alkynes and sodium sulfinates and a wide range of phenols/thiophenols and naphthols are viable in this transformation. Green protocol and wide substrate scope are the remarkable characteristics of this multicomponent procedure.

Recommanded Product: 3-(Trifluoromethyl)phenol. About 3-(Trifluoromethyl)phenol, If you have any questions, you can contact Ansari, MY; Kumar, N; Kumar, A or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about ARYLBORONIC ACIDS; IPSO-HYDROXYLATION; ROOM-TEMPERATURE; PHENOLS; MILD; CONVERSION; CATALYSIS; LIGAND; ESTERS; O-2, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21867011]. Quality Control of 3-(Trifluoromethyl)phenol. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Yin, WY; Pan, XZ; Leng, WX; Chen, J; He, HF. The CAS is 98-17-9. Through research, I have a further understanding and discovery of 3-(Trifluoromethyl)phenol

Molecular oxygen is the most important green-oxidant due to its excellent properties. However, the effective utilization of molecular oxygen remains a major challenge in modern chemistry. Herein, we report the development a rapid, green and efficient microwave-assisted protocol for the air oxidation of boronic acids to phenols and alcohols under transition metal-free conditions. In the presence of KOH and DMSO, high yields of the expected phenols and alcohol were obtained with microwave-assistance, and a variety of functional groups were tolerated in this procedure. Notably, this transition metal-free method represents a breakthrough in both organic synthesis and green chemistry for the oxidative hydroxylation of boronic acids to phenols and alcohols.

Quality Control of 3-(Trifluoromethyl)phenol. About 3-(Trifluoromethyl)phenol, If you have any questions, you can contact Yin, WY; Pan, XZ; Leng, WX; Chen, J; He, HF or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

I found the field of Chemistry very interesting. Saw the article Lewis Acid-Activated Reactions of Silyl Ketenes for the Preparation of alpha-Silyl Carbonyl Compounds published in 2019. Recommanded Product: 98-17-9, Reprint Addresses Pentzer, EB (corresponding author), Texas A&M Univ, Dept Mat Sci & Engn, 3003 TAMU, College Stn, TX 77843 USA.; Pentzer, EB (corresponding author), Texas A&M Univ, Dept Chem, 3003 TAMU, College Stn, TX 77843 USA.. The CAS is 98-17-9. Through research, I have a further understanding and discovery of 3-(Trifluoromethyl)phenol

Silyl-substituted ketenes are attractive molecular building blocks due to their stability and ease of storage, as opposed to unstable alkyl and aryl ketenes. To better understand the reactivity of silyl ketenes and, in turn, their use in the preparation of highly functionalized small molecules, the reaction of silyl ketenes with different nucleophiles was studied. The addition of alcohol, amine, or thiol nucleophiles to the central carbon of silyl ketene, followed by proton transfer afforded alpha-silyl ester, amide, or thio-ester, respectively. Catalytic amounts of Lewis acid greatly increase the rate of the reaction, and the impact of nucleophile, Lewis acid, and silyl substituent are evaluated. The small molecules produced from these reactions give insight into the use of silyl ketenes as building blocks for complex molecular structures.

About 3-(Trifluoromethyl)phenol, If you have any questions, you can contact Mitchell, SM; Xiang, Y; Matthews, R; Arnburgey, AM; Pentzer, EB or concate me.. Recommanded Product: 98-17-9

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Quality Control of 3-(Trifluoromethyl)phenol. Wu, YB; Xiao, L; Mao, CL; Zang, ZL; Zhou, CH; Cai, GX in [Wu, Yun-Bin; Xiao, Lin; Mao, Chun-Li; Zang, Zhong-Lin; Zhou, Cheng-He; Cai, Gui-Xin] Southwest Univ, Key Lab Luminescent & Real Time Analyt Chem, Minist Educ,Sch Chem & Chem Engn, Key Lab Appl Chem Chongqing Municipal,Inst Bioorg, Chongqing 400715, Peoples R China; [Cai, Gui-Xin] Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China published Regio- and Stereoselective Synthesis of Enynyl-Aryl Ethers Enabled by Copper/Iodide Tandem Catalysis in 2019, Cited 82. The Name is 3-(Trifluoromethyl)phenol. Through research, I have a further understanding and discovery of 98-17-9.

An approach to preparing enynyl-aryl ethers from phenols and phenylacetylenes is described. This method without extra ligands, overcoming the favored Glaser-Hay dimerization of alkyne, features a wide substrate scope (38 examples including endofolliculina and indole) and the merits of high atom and step economy, good regio- and stereoselectivity (Z-isomers major) in moderate to good isolated yields. Mechanistic studies show that the reaction is enabled by distinctive copper/iodide tandem catalysis.

About 3-(Trifluoromethyl)phenol, If you have any questions, you can contact Wu, YB; Xiao, L; Mao, CL; Zang, ZL; Zhou, CH; Cai, GX or concate me.. Quality Control of 3-(Trifluoromethyl)phenol

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Enantioselective Synthesis of 3,3 ‘-Disubstituted 2-Amino-2 ‘-hydroxy-1,1 ‘-binaphthyls by Copper-Catalyzed Aerobic Oxidative Cross-Coupling WOS:000620194400001 published article about ASYMMETRIC CATALYSIS; BINOL; DERIVATIVES; 2-NAPHTHOL; ACTIVATION; LIGANDS; ACID in [Zhao, Xiao-Jing; Li, Zi-Hao; Ding, Tong-Mei; Tian, Jin-Miao; Tu, Yong-Qiang; Wang, Ai-Fang; Xie, Yu-Yang] Shanghai Jiao Tong Univ, Shanghai Key Lab Mol Engn Chiral Drugs, Frontiers Sci Ctr Transformat Mol, Sch Chem & Chem Engn, Shanghai 200240, Peoples R China; [Tu, Yong-Qiang] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China; [Tu, Yong-Qiang] Lanzhou Univ, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China in 2021, Cited 70. COA of Formula: C7H5F3O. The Name is 3-(Trifluoromethyl)phenol. Through research, I have a further understanding and discovery of 98-17-9

A challenging direct asymmetric catalytic aerobic oxidative cross-coupling of 2-naphthylamine and 2-naphthol, using a novel Cu-I/SPDO system, has been successfully developed for the first time. Enantioenriched 3,3 ‘-disubstituted NOBINs were achieved and could be readily derived to divergent chiral ligands and catalysts. This reaction features high enantioselectivities (up to 96 % ee) and good yields (up to 80 %). The DFT calculations suggest that the F-H interactions between CF3 of L17 and H-1,8 of 2-naphthol, and the pi-pi stacking between the two coupling partners could play vital roles in the enantiocontrol of this cross-coupling reaction.

About 3-(Trifluoromethyl)phenol, If you have any questions, you can contact Zhao, XJ; Li, ZH; Ding, TM; Tian, JM; Tu, YQ; Wang, AF; Xie, YY or concate me.. COA of Formula: C7H5F3O

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 98-17-9. Authors Ning, L; Wang, SM; Du, L; Guo, BY; Zhang, JJ; Lu, HZ; Dong, YH in ROYAL SOC CHEMISTRY published article about in [Ning, Lei; Wang, Simin; Guo, Bingyi; Zhang, Jianjun; Lu, Huizhe; Dong, Yanhong] China Agr Univ, Dept Chem, Beijing 100193, Peoples R China; [Ning, Lei; Wang, Simin; Guo, Bingyi; Zhang, Jianjun; Lu, Huizhe; Dong, Yanhong] China Agr Univ, Innovat Ctr Pesticide Res, Beijing 100193, Peoples R China; [Du, Lin] China Agr Univ, Coll Agron & Biotechnol, Beijing 100193, Peoples R China in 2021, Cited 41. The Name is 3-(Trifluoromethyl)phenol. Through research, I have a further understanding and discovery of 98-17-9

A series of azamacrolides containing the carbamate or urea moiety were synthesized and evaluated for their fungicidal activities against several agriculturally important pathogens. In addition, they were investigated for their ability to inhibit quorum sensing in Agrobacterium tumefaciens. The results showed that most of the derivatives had moderate to high fungicidal activities against the tested fungi, especially towards Sclerotinia sclerotiorum. Additionally, D16-19 could be used as a potential broad-spectrum fungicide while D16-4 exhibited a fungicidal activity (EC50 = 1.87 mg L-1) similar to that of carbendazim (EC50 = 1.34 mg L-1) against S. sclerotiorum. The three-dimensional Quantitative Structure-Activity Relationship (3D-QSAR) models were also established based on the experimental results and they would provide valuable information for further optimization. Moreover, D16-17 not only showed a better fungicidal activity against S. sclerotiorum but also had the highest ability to inhibit quorum sensing. These findings suggested that some azamacrolide compounds hold potential for the development of novel fungicides or inhibitors of quorum sensing.

SDS of cas: 98-17-9. About 3-(Trifluoromethyl)phenol, If you have any questions, you can contact Ning, L; Wang, SM; Du, L; Guo, BY; Zhang, JJ; Lu, HZ; Dong, YH or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Electrochemical Reductive Smiles Rearrangement for C-N Bond Formation WOS:000455285800003 published article about H FUNCTIONALIZATION; OXIDATIVE AMINATION; ELECTRON-TRANSFER; AMIDYL RADICALS; METAL; GENERATION; CLEAVAGE; ETHERS; ELECTROSYNTHESIS; HETEROARENES in [Chang, Xihao; Zhang, Qinglin; Guo, Chang] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Anhui, Peoples R China in 2019, Cited 77. The Name is 3-(Trifluoromethyl)phenol. Through research, I have a further understanding and discovery of 98-17-9. Safety of 3-(Trifluoromethyl)phenol

A conceptually new and synthetically valuable radical Smiles rearrangement reaction is reported under undivided electrolytic conditions. This protocol employs an entirely new strategy for the electrochemical radical Smiles rearrangement. Remarkably, an amidyl radical generated from the cleavage of the N-O bond under reductive electrolytic conditions plays a crucial role in this transformation. Various hydroxylamine derivatives bearing different substituents are suitable in this electrochemical transformation, furnishing the corresponding amides in up to 86% yield.

About 3-(Trifluoromethyl)phenol, If you have any questions, you can contact Chang, XH; Zhang, QL; Guo, C or concate me.. Safety of 3-(Trifluoromethyl)phenol

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Biomimetic synthesis and anti-inflammatory evaluation of violacin A analogues WOS:000656969600006 published article about III POLYKETIDE SYNTHASE; NF-KAPPA-B; METABOLITES; MECHANISM; OXIDASE in [Wu, Wenxi; Mu, Yu; Liu, Bo; Wang, Zixuan; Guan, Peipei; Han, Li; Huang, Xueshi] Northeastern Univ, Coll Life & Hlth Sci, Inst Microbial Pharmaceut, Shenyang 110819, Peoples R China; [Jiang, Mingguo] Guangxi Univ Nationalities, Sch Marine Sci & Biotechnol, Guangxi Key Lab Polysaccharide Mat & Modificat, Nanning 530008, Peoples R China in 2021, Cited 25. The Name is 3-(Trifluoromethyl)phenol. Through research, I have a further understanding and discovery of 98-17-9. Category: indole-building-block

Violacin A, a chromanone derivative, isolated from a fermentation broth of Streptomyces violaceoruber, has excellent anti-inflammatory potential. Herein, a biogenetically modeled approach to synthesize violacin A and twenty-five analogues was described, which involved the preparation of aromatic polyketide precursor through Claisen condensation and its spontaneous cyclization. The inhibitory effect on nitric oxide (NO) production of all synthetic molecules was evaluated by lipopolysaccharide (LPS)-induced Raw264.7 cells. The results revealed that introduction of aliphatic amine moieties on C-7 obviously improved the anti-inflammation effect of violacin A, and also the aromatic ether instead of ketone group at side chain was favorable to increase the activity. Among them, analogue 7a and 16d were screened as the most effective anti-inflammatory candidates. Molecular mechanism research revealed that 7a and 16d acquired anti-inflammatory ability due to the inhibition of NF-KB signaling pathway.

About 3-(Trifluoromethyl)phenol, If you have any questions, you can contact Wu, WX; Mu, Y; Liu, B; Wang, ZX; Guan, PP; Han, L; Jiang, MG; Huang, XS or concate me.. Category: indole-building-block

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles