Category: 99-93-4

Product Details of 99-93-4. In 2020.0 CERAM INT published article about BISMUTH OXYHALIDES; DEGRADATION; NANOCOMPOSITES; FABRICATION; PERFORMANCE; HETEROJUNCTION; THICKNESS in [Jiang, Zao; Yin, Xiuyu; Xu, Longjun; Liu, Chenglun; Wang, Hailong] Chongqing Univ, State Key Lab Coal Mine Disaster Dynam & Control, Chongqing 400044, Peoples R China; [Liu, Chenglun] Chongqing Univ, Coll Chem & Chem Engn, Chongqing 400044, Peoples R China; [Xiao, Chu] Army Logist Univ PLA, Chongqing 401331, Peoples R China in 2020.0, Cited 38.0. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4.

In this wok, a novel Bi24O31Br10/nano-ZnO composite photocatalyst has been synthesized with solvothermal method. The photocatalytic ability of the composite photocatalyst is estimated through degrading Rhodomine B (RhB) under visible light. The RhB degradation rate exceeds 90% in 40 min for the Bi24O31Br10/nano-ZnO (5%) composite, showing the most remarkable photocatalytic abilities. The excellent photocatalytic performance can be explained by the successful detachment and motion of photo-induced electrons (e(-)) and holes (h(+)) in the composite photocatalyst. Additionally, a probable photo-catalytic principle of the Bi24O31Br10/nano-ZnO composite for RhB degradation is discussed. This study could provide an original visible light driven photocatalyst on efficiently purifying dye wastewaters.

Product Details of 99-93-4. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Name: 4′-Hydroxyacetophenone. Authors Sprakel, LMJ; Bargeman, G; Sanchez, LG; Schuur, B in WILEY published article about in [Sprakel, Lisette M. J.; Schuur, B.] Univ Twente, Fac Sci & Technol, Sustainable Proc Technol Grp, Drienerlolaan 5,Meander 221, NL-7522 NB Enschede, Netherlands; [Bargeman, G.] Nouryon Chem BV, Res Dev & Innovat, Expert Capabil Grp, Zutphenseweg 10,POB 70, NL-7400 AA Deventer, Netherlands; [Bargeman, G.; Sanchez, Lara G.] Univ Twente, Fac Sci & Technol, Membrane Sci & Technol Cluster, Drienerlolaan 5, NL-7522 NB Enschede, Netherlands in 2021.0, Cited 20.0. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4

BACKGROUND Although phenol is a key intermediate in the plastics and polycarbonate industry, it is also a toxic component that requires removal from dilute aqueous streams, potentially by liquid-liquid extraction (LLX). For LLX, cumene is suggested as a solvent as it is already present in processes in the polycarbonate industry. For the recovery of cumene from phenol by distillation, knowledge on vapor-liquid equilibrium (VLE) behavior is important, in combination with how this is affected by other components possibly present as an impurity or explicitly added as a solvent. This was investigated in this work. RESULTS The binary cumene-phenol system shows a tangent pinch in the binary VLE diagram. Addition of a range of impurities and solvents showed that hydrogen bond accepting compounds strongly improve the relative volatility of the mixture, whereas dodecane, not capable of forming hydrogen bonds, has a negative effect on the relative volatility. CONCLUSION Addition of polar components with hydrogen bonding abilities, i.e. ketones or ethers, affected the relative volatility of cumene over phenol the most positively. Combining two types of components results in similar effects, and clear synergistic effects could not be shown based on current VLE measurements. Addition of an apolar component in combination with polar components with hydrogen abilities had only a minor effect on the relative volatility. (c) 2021 The Authors. Journal of Chemical Technology and Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry (SCI).

Name: 4′-Hydroxyacetophenone. Welcome to talk about 99-93-4, If you have any questions, you can contact Sprakel, LMJ; Bargeman, G; Sanchez, LG; Schuur, B or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: C8H8O2. Safabakhsh, T; Daraei, H; Saha, N; Khodakarim, S in [Safabakhsh, Tahereh] Isfahan Univ Med Sci, Int Educ Ctr, Esfahan, Iran; [Daraei, Hasti] Shahid Beheshti Univ Med, Sch Publ Hlth & Safety, Student Res Comm, Tehran, Iran; [Saha, Narottam] Univ Queensland, Sustainable Minerals Inst, Ctr Mined Land Rehabil, Brisbane, Qld, Australia; [Khodakarim, Soheila] Shahid Beheshti Univ Med Sci, Sch Publ Hlth & Safety, Dept Epidemiol, Tehran, Iran published Degradation of Bisphenol A from aqueous solutions using Fe3O4 as a persulfate activator in 2019.0, Cited 28.0. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4.

The present study investigated the degradation of bisphenol A (BPA) from aqueous solution using Fe3O4/persulfate process. The effects of pH (3, 5, 7 and 11), persulfate (PS) concentrations (1, 2, 5 and 10 mM), Fe3O4 magnetic nanoparticle doses (0.5, 1, 1.5 and 2 g/L), and contact time (5, 10, 20 and 30 min) on BPA removal were examined. The effect of all factors was significant (p < 0.05), and the optimal conditions were: pH value of 3, Fe3O4 dose of 2 g/L, BPA concentration of 0.1 mg/L, and contact time of 30 min. The BPA removal efficiency under optimal conditions was 98%. The results of this work indicate that Fe3O4 nanoparticles can be used as an effective catalyst and adsorbent for the removal of BPA from water and industrial wastewater. Analysis of by-products of BPA using GC-MS detected the presence of compounds with lower molecular weights (4-hydroxyacetophenone, 4-isopropenylphenol, benzoquinone and succinic acid) relative to BPA. HPLC of Formula: C8H8O2. About 4′-Hydroxyacetophenone, If you have any questions, you can contact Safabakhsh, T; Daraei, H; Saha, N; Khodakarim, S or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article A bioinformatics investigation into molecular mechanism of Yinzhihuang granules for treating hepatitis B by network pharmacology and molecular docking verification WOS:000548306700001 published article about CELL-CYCLE; HEPATOCELLULAR-CARCINOMA; DRUG CLASSIFICATION; VIRUS; UPDATE; KINASE; GENES; CDK6; INFECTION; VISUALIZATION in [Zhang, Jingyuan; Liu, Xinkui; Zhou, Wei; Wu, Jiarui; Guo, Siyu; Jia, Shanshan; Liu, Yingying; Zhang, Xiaomeng; Wang, Miaomiao] Beijing Univ Chinese Med, Beijing 100102, Peoples R China; [Cheng, Guoliang; Li, Bingbing] State Key Lab Gener Manufacture Technol Chinese T, Linyi 276000, Shandong, Peoples R China in 2020.0, Cited 81.0. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4. Computed Properties of C8H8O2

Yinzhihuang granules (YZHG) is a patented Chinese medicine for the treatment of hepatitis B. This study aimed to investigate the intrinsic mechanisms of YZHG in the treatment of hepatitis B and to provide new evidence and insights for its clinical application. The chemical compounds of YZHG were searched in the CNKI and PUBMED databases, and their putative targets were then predicted through a search of the SuperPred and Swiss Target Prediction databases. In addition, the targets of hepatitis B were obtained from TTD, PharmGKB and DisGeNET. The abovementioned data were visualized using Cytoscape 3.7.1, and network construction identified a total of 13 potential targets of YZHG in the treatment of hepatitis B. Molecular docking verification showed that CDK6, CDK2, TP53 and BRCA1 might be strongly correlated with hepatitis B treatment. Furthermore, GO and KEGG analyses indicated that the treatment of hepatitis B by YZHG might be related to positive regulation of transcription, positive regulation of gene expression, the hepatitis B pathway and the viral carcinogenesis pathway. Network pharmacology intuitively shows the multicomponent, multitarget and multichannel pharmacological effects of YZHG in the treatment of hepatitis B and provides a scientific basis for its mechanism of action.

Welcome to talk about 99-93-4, If you have any questions, you can contact Zhang, JY; Liu, XK; Zhou, W; Cheng, GL; Wu, JR; Guo, SY; Jia, SS; Liu, YY; Li, BB; Zhang, XM; Wang, MM or send Email.. Computed Properties of C8H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Zhang, H; He, YL; Lai, LD; Yao, G; Lai, B in [Zhang, Heng; He, Yongli; Lai, Leiduo; Lai, Bo] Sichuan Univ, State Key Lab Hydraul & Mt River Engn, Coll Architecture & Environm, Chengdu 610065, Peoples R China; [Zhang, Heng; He, Yongli; Lai, Leiduo; Yao, Gang; Lai, Bo] Sichuan Univ, Sino German Ctr Water & Hlth Res, Chengdu 610065, Peoples R China; [Yao, Gang] Rhein Westfal TH Aachen, Inst Environm Engn, Aachen, Germany published Catalytic ozonation of Bisphenol A in aqueous solution by Fe3O4-MnO2 magnetic composites: Performance, transformation pathways and mechanism in 2020.0, Cited 45.0. HPLC of Formula: C8H8O2. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4.

In this study, Fe3O4-MnO2 magnetic composites were prepared and used as catalyst for the catalytic ozonation of BPA in aqueous solution. First, characterization results proved that Fe3O4-MnO2 magnetic composites were prepared successfully. Meanwhile, the advantage of Fe3O4-MnO2/O-3 system was demonstrated by control experiments. The degradation efficiency of BPA in Fe3O4-MnO2 process reached 97.0% under the conditions: Fe3O4-MnO2 = 100 mg/L, O-3 flow rate = 100 mL/min, initial solution pH = 7.0. In addition, the effects of catalyst dosage, O-3 flow rate and initial solution pH on the degradation of BPA were studied respectively. Moreover, the recyclability and stability of Fe3O4-MnO2 magnetic composites were also investigated. The results showed that Fe3O4-MnO2 magnetic composites have high catalytic activity, stability and recyclability for BPA degradation. Furthermore, the degradation intermediates of BPA were detected and the degradation pathways of BPA were proposed comprehensively. Finally, the possible reaction mechanism of Fe3O4-MnO2/O-3 process was proposed. In brief, all the results confirmed that the Fe3O4-MnO2/O-3 process was a simple, nonhazardous, efficient and promising technology for the degradation of BPA in aqueous solution.

HPLC of Formula: C8H8O2. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about COLCHICINE BINDING; TUBULIN INHIBITORS; COMBRETASTATIN; POTENT; SITE; CHALCONOIDS; CANCER, Saw an article supported by the Research Council of Mazandaran University of Medical Sciences, Sari, Iran [2572]. Recommanded Product: 4′-Hydroxyacetophenone. Published in ACADEMIC PRESS INC ELSEVIER SCIENCE in SAN DIEGO ,Authors: Ansari, M; Shokrzadeh, M; Karima, S; Rajaei, S; Hashemi, SM; Mirzaei, H; Fallah, M; Emami, S. The CAS is 99-93-4. Through research, I have a further understanding and discovery of 4′-Hydroxyacetophenone

Several flexible and rigid analogs of 4H-1,2,4-triazoles (compounds 8a-g and 9a-g) bearing trimethoxyphenyl pharmacophoric unit, were designed and synthesized as potential anticancer agents. The in vitro cytotoxic assay indicated that both flexible and rigid analogs (8 and 9, respectively) can potentially inhibit the growth of cancerous cells (A549, MCF7, and SKOV3), with IC50 values less than 5.0 mu M. Furthermore, compounds 10a-l as regional isomers of compounds 9 exhibited remarkable cytotoxic activity with IC50 values ranging from 0.30 to 5.0 mu M. The rigid analogs 9a, 10h and 10k were significantly more potent than etoposide against MCF7, SKOV3 and A549 cells, respectively. These compounds showed high selectivity towards cancer cells over normal cells, as they had no significant cytotoxicity against L929 cells. In addition, the representative compounds 9a and 10h could inhibit the tubulin polymerization at micro-molar levels. By determining changes in the colchicine-tubulin fluorescence, it was suggested that compound 10h could bind to the tubulin at the colchicine pocket. The molecular docking study further confirmed the inhibitory activity of promising compounds 9a, 10h and 10k on tubulin polymerization through binding to the colchicine-binding site.

Recommanded Product: 4′-Hydroxyacetophenone. Welcome to talk about 99-93-4, If you have any questions, you can contact Ansari, M; Shokrzadeh, M; Karima, S; Rajaei, S; Hashemi, SM; Mirzaei, H; Fallah, M; Emami, S or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Stereoselective Formation of beta-O-4 Structures Mimicking Softwood Lignin Biosynthesis: Effects of Solvent and the Structures of Quinone Methide Lignin Models WOS:000473251400005 published article about THREO FORMS; ERYTHRO/THREO RATIO; STEREO-PREFERENCE; DIASTEREOMERS; REACTIVITY; OXIDATION; DEGRADATION; DELIGNIFICATION; HARDWOOD; SPRUCE in [Zhu, Xuhai; Yokoyama, Tomoya; Matsumoto, Yuji] Univ Tokyo, Grad Sch Agr & Life Sci, Dept Biomat Sci, Wood Chem Lab,Bunkyo Ku, Tokyo 1138657, Japan; [Akiyama, Takuya] Forestry & Forest Prod Res Inst, Dept Forest Resource Chem, Wood Chem Lab, 1 Matsunosato, Tsukuba, Ibaraki 3058687, Japan in 2019.0, Cited 41.0. Recommanded Product: 99-93-4. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4

p-Quinone methide (QM) is formed as an intermediate during lignin biosynthesis. The aromatization of the QM by the attack of a nucleophile at the a-position of its side chain generates a phenolic hydroxy group in a growing polymer and creates stereoisomeric forms in the side chain. A series of beta-O-4-aryl ether QMs was reacted with water at 25 degrees C to replicate the formation of p-hydro)ryphenyl (H) and guaiacyl (C) beta-O-4 structures in plant cell walls. Water addition occurred in 3-methoxy-substituted QMs (G-type QMs) with half-lives (t(1/2)) between 13 and 15 min, at pH 7, in 50% water solution (dioxane water, 1:1). The rate increased as the water concentration increased to 99% (t(1/2), 1.2-1.4 min). Similar solvent effects were observed for more reactive nonsubstituted QMs (H-type QMs with t(1/2) of <1 min). Consequently, t(1/2) of the H-type QMs was shorter than that of the G-type QMs under every solvent condition. Upon increasing the water concentration, the variation in the erythro/threo ratios of the four dimeric beta-O-4 products increased. Interestingly, the effect of pH on the stereopreference, which was observed in 50% water solution, was small and became imperceptible as the water concentration increased to 99%, suggesting that the effect of the solvent, as well as the effect of the pH, plays an important role in understanding the reaction conditions in cell walls during lignin biosynthesis. The threo isomer was preferentially formed in the four dimeric beta-O-4 structures, which is inconsistent with the structural features of compression wood lignin rich in H-units. However, the erythro-selective formation was attained in an H-type QM at every pH studied (pH 3.5-7) by introducing a biphenyl structure into the beta-etherified ring moiety. Recommanded Product: 99-93-4. Welcome to talk about 99-93-4, If you have any questions, you can contact Zhu, XH; Akiyama, T; Yokoyama, T; Matsumoto, Y or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Wu, YM; Tang, CR; Rui, RM; Yang, LM; Ding, W; Wang, JY; Li, YM; Lai, CC; Wang, YP; Luo, RH; Xiao, WL; Zhang, HB; Zheng, YT; He, YP in INST MATERIA MEDICA, CHINESE ACAD MEDICAL SCIENCES published article about REVERSE-TRANSCRIPTASE INHIBITORS; ANTI-HIV-1 ACTIVITY; DABOS; DISCOVERY; DESIGN; FAMILY in [Wu, Yumeng; Rui, Ruomei; Ding, Wei; Wang, Jiangyuan; Li, Yiming; Wang, Yueping; Xiao, Weilie; Zhang, Hongbing; He, Yanping] Yunnan Univ, Sch Chem Sci & Technol, Key Lab Med Chem Nat Resources, Minist Educ & Yunnan Prov, Kunming 650091, Yunnan, Peoples R China; [Tang, Chengrun; Yang, Liumeng; Luo, Ronghua; Zheng, Yongtang] Chinese Acad Sci, Natl Kunming High Level Biosafety Res Ctr Nonhuma, Key Lab Bioact Peptides Yunnan Prov,Key Lab Anim, Kunming Inst Zool,KIZ CUHK Joint Lab Bioresources, Kunming 650223, Yunnan, Peoples R China; [Lai, Christopher C.] NCI, Chem Biol Lab, Ctr Canc Res, NIH, Frederick, MD 21702 USA; [Tang, Chengrun] Kunming Med Univ, Sch Pharmaceut Sci, Kunming 650500, Yunnan, Peoples R China; [Tang, Chengrun] Kunming Med Univ, Yunnan Key Lab Pharmacol Nat Prod, Kunming 650500, Yunnan, Peoples R China in 2020.0, Cited 40.0. Product Details of 99-93-4. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4

A series of 2-(((5-akly/aryl-1H-pyrazol-3-yl)methyl)thio)-5-alkyl-6-(cyclohexylmethyl)-pyrimidin-4(3H)-ones were synthesized and their anti-HIV-1 activities were evaluated. Most of these compounds were highly active against wild-type (WT) HIV-1 strain (IIIB) with EC50 values in the range of 0.0038-0.4759 mmol/L. Among those compounds, I-11 had an EC50 value of 3.8 nmol/L and SI (selectivity index) of up to 25,468 indicating excellent activity against WT HIV-1. In vitro anti-HIV-1 activity and resistance profile studies suggested that compounds I-11 and I-12 displayed potential anti-HIV-1 activity against laboratory adapted strains and primary isolated strains including different subtypes and tropism strains (EC(50)s range from 4.3 to 63.6 nmol/L and 18.9-219.3 nmol/L, respectively). On the other hand, it was observed that those two compounds were less effective with EC50 values of 2.77 and 4.87 mmol/L for HIV-1A(17) (K103N + Y181C). The activity against reverse transcriptase (RT) was also evaluated for those compounds. Both I-11 and I-12 obtained sub-micromolar IC50 values showing their potential in RT inhibition. The pharmacokinetics examination in rats indicated that compound I-11 has acceptable pharmacokinetic properties and bioavailability. Preliminary structure-activity relationships and molecular modeling studies were also discussed. (C) 2020 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.

Product Details of 99-93-4. Welcome to talk about 99-93-4, If you have any questions, you can contact Wu, YM; Tang, CR; Rui, RM; Yang, LM; Ding, W; Wang, JY; Li, YM; Lai, CC; Wang, YP; Luo, RH; Xiao, WL; Zhang, HB; Zheng, YT; He, YP or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: 99-93-4. Zhang, XL; Sheng, SR; Pan, Y; Huang, ZZ; Liu, XL in [Zhang, Xiao-Lan; Sheng, Shou-Ri; Pan, Yang; Huang, Zhen-Zhong; Liu, Xiao-Ling] Jiangxi Normal Univ, Minist Educ, Key Lab Funct Small Organ Mol, Nanchang 330022, Jiangxi, Peoples R China published Organosoluble, low dielectric constant and highly transparent fluorinated pyridine-containing poly(ether imide)s derived from new diamine: 4-(4-trifluoromethyl)phenyl-2,6-bis[4-(4-amino-2-trifluoromethylphenoxy)phenyl]pyridine in 2019.0, Cited 31.0. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4.

A new aromatic diamine, 4-(4-trifluoromethyl)phenyl-2,6-bis[4-(4-amino-2-trifluoromethylphenoxy)phenyl]pyridine, was synthesized by a modified Chichibabin reaction of 4-(4-nitro-2-trifluoromethylphenoxy)acetophenone with 4-triflouromethylbenzaldehyde, followed by catalytic reduction. A series of fluorinated pyridine-containing aromatic poly(ether imide)s (PEIs) were prepared from the diamine monomer with various aromatic dianhydrides via conventional two-step thermal imidization method. The resulting PEIs had inherent viscosities values of 0.68-0.90 dL/g, and could be cast and thermally converted into transparent, flexible, and tough polymer films. These PEIs were predominantly amorphous, had good solubility in common solvents such as NMP, DMAc and m-cresol at room temperature, and displayed excellent thermal stability with the glass transition temperatures of 258-315 degrees C, the temperatures at 5% weight loss of 550-585 degrees C, and the residue of higher than 55% at 750 degrees C in nitrogen. Moreover, the PEIs films showed outstanding mechanical properties with tensile strengths of 74.8-103.5 MPa, tensile moduli of 1.08-1.45 GPa, and elongations at break of 10.6-24.4%. These PEIs also exhibited low dielectric constants of 2.81-2.98 (1 MHz) and water uptake 0.39-0.68%, as well as high optical transparency with the UV cutoff wavelength in the 350-378 nm range and the wavelength of 80% transparency in the range of 412-510 nm. [GRAPHICS] . A series of fluorinated pyridine-containing poly( ether imide) s derived from a new diamine 4-( 4-trifluoromethyl) phenyl-2,6-bis[ 4-( 4-amino-2-trifluoromethylphenoxy) phenyl] pyridine with various dianhydrides were investigated. The resulting polymers exhibited improved solubility, high optical transparency and low dielectric constants, combined with good thermal and mechanical properties.

Recommanded Product: 99-93-4. Welcome to talk about 99-93-4, If you have any questions, you can contact Zhang, XL; Sheng, SR; Pan, Y; Huang, ZZ; Liu, XL or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Bisphenol A degradation pathway and associated metabolic networks in Escherichia coli harboring the gene encoding CYP450 WOS:000524462500016 published article about CYTOCHROME-P450; BIODEGRADATION; CELLS; AMPG in [Wang, Wenxin; Qin, Huaming; Long, Yan; Ye, Jinshao] Jinan Univ, Sch Environm, Guangdong Key Lab Environm Pollut & Hlth, Guangzhou 510632, Peoples R China; [Yu, Henan] Guangdong Ocean Engn Technol Sch, Guangzhou 510320, Peoples R China; [Qu, Yanfen] Zhongji Ecol Sci & Technol Co Ltd, Guangzhou 511443, Peoples R China in 2020.0, Cited 40.0. Recommanded Product: 99-93-4. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4

Although bisphenol A (BPA) can be transformed by CYP450, the metabolic networks involved in regulating the transformation processes are not clear. In this study, Escherichia coli. harboring the gene encoding CYP450 was used as a model to elucidate the BPA degradation pathway and the associated metabolic network using a proteomic approach. The results showed that CYP450 promotes the transformation of BPA, generating 1,2-bis(4-hydroxyphenyl)-2-propanol and 2,2-bis(4-hydroxyphenyl)-1-propanol, with hydroquinone and 4-(2-hydroxypropan-2-yl)phenol formed in another pathway. The DNA adducts formed by 1,4-benzoquinone were reduced, and CYP450 played a positive role in cellular homeostasis by promoting the transformation of BPA and mismatch repair. An increase in the synthesis of cell membrane lipids was observed after dislodging BPA. BPA disturbed folate metabolism by decreasing the abundance of dihydrofolate reductase, which inhibited microbial metabolism in the absence of CYP450. The findings of this study revealed the molecular mechanism associated with the metabolic network responsible for pollutant tolerance and degradation.

Recommanded Product: 99-93-4. Welcome to talk about 99-93-4, If you have any questions, you can contact Wang, WX; Yu, HN; Qin, HM; Long, Y; Ye, JS; Qu, YF or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles